Faculty

Institution

Unit

Venue

Willard W. Sharp

Associate Professor of Medicine

University of Chicago

Affiliations

Pritzker School of Medicine

Medicine

Willard W. Sharp is currently serving as a Medicine Associate Professor of Medicine at University of Chicago.

Honors

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Experiences

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Education

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Willard W. Sharp

University of Chicago

Associate Professor of Medicine

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cardiology emergency medicine physiology respiratory medicine cardiac arrest resuscitation pharmacology membrane biology cardiovascular research mitochondrial function electrophysiology mammalian biology cardiovascular physiology cell biology vascular biology circulatory physiology cellular physiology molecular physiology redox biology applied physiology molecular medicine veterinary medicine cardiovascular disease animal physiology reperfusion injury cardiopulmonary resuscitation emergency management gene expression human physiology mitochondrial fission therapeutic hypothermia cardioprotection murine model biomechanics liver physiology cardiomyopathy cardiovascular function rna biology pulmonary arterial hypertension respiratory neurobiology oxygen sensing cellular biochemistry molecular cell biology cell physiology cellular biology diastolic function protein function heme homeostasis cardiac muscle doxorubicin-induced cardiomyopathy mechanical regulation critical care nurse avian medicine treatment and prevention renal function novel therapies therapeutic efficacy cell biomechanics medical genetics ischemic syndrome cardiovascular toxicity cost issue phytochemistry plant immunity phytopharmacology cellular immune responses cell migration diastolic dysfunction myocardial ischemia-reperfusion injury therapeutic benefits female rats mechanical forces focal adhesion cardiac myocytes mitochondrial dna damage pulmonary hypertension right ventricular dysfunction

Notable Scholarly Works

Notable Federal Grants

Collaborators

Acute Ischemic Stroke in a Marathon Runner: Last Known Well at Mile 22 Case Report. Prehospital Emergency Care (2025)

Katie L. TatarisWillard W. SharpGeorge T. ChiampasAmeera S. Haamid

intensive careresuscitationstrokeemergency careacute ischemic strokeacute carecritical careprehospital caremarathon runneremergency medicine

Arnt-Dependent Hif-2α Signaling Protects Cardiac Microvascular Barrier Integrity and Heart Function Post-Myocardial Infarction. Communications Biology (2025)

Karim UllahLizhuo AiYan LiLifeng LiuQin ZhangKaichao PanZainab HumayunLin PiaoAlbert SitikovQiong ZhaoQiaozhu SuWillard SharpYun FangDavid WuJames K. LiaoRongxue Wu

myocardial infarctioncardiologycardiovascular functioncell signalingsystems biologybiologyvascular biologycardiovascular researchmolecular biologymicrovascular dysfunction

Divergent Ventilatory Responses During Opioid-Induced Respiratory Depression in Response to Repeated Fentanyl Use. American Journal of Physiology-Lung Cellular and Molecular Physiology (2025)

Karan G. RaiChinwendu U. NwakuduCaroline C. SzujewskiBrigitte M. BroweGia E. FisherWillard W. SharpAndrew K. TrybaAlfredo J. Garcia

pulmonary pharmacologyopioid-induced respiratory depressionsubstance use disordersdivergent ventilatory responsesrespiratory medicinephysiologyfentanyl usemolecular physiology

Rediscovery of Acute Lung Injury in Cardiac Arrest: Breathing Fresh Air Into a Neglected Component of the Post-Cardiac Arrest Syndrome. Resuscitation (2025)

Willard W SharpLin Piao

resuscitationcardiopulmonary resuscitationacute lung injurypost-cardiac arrest syndromebreathing fresh aircardiac arrestemergency medicine

A Novel Preclinical Model of Fentanyl-Induced Cardiorespiratory Collapse to Investigate Resuscitation Outcomes. Physiology (2024)

Lin PiaoYonghu FangAlfredo J. GarciaWillard Sharp

resuscitationcardiologyresuscitation outcomesfentanyl-induced cardiorespiratory collapsehuman physiologyrespiratory medicinephysiologycritical careneurophysiologynovel preclinical modelrespiration (physiology)emergency medicine

Assessment of an Organizational Effort to Increase Emergency Medicine Faculty on National Institutes of Health Study Sections. Academic Emergency Medicine (2024)

Christian D. PulciniDavid J. BartonMichael CassaraJoshua J. DavisStephanie C. DeMasiEdward J. DurantNidhi GargColin GreinederMelissa McMillianJames H. PaxtonMichael A. PuskarichJody A. VogelAmbrose H. WongWillard W. Sharp

emergency medicine facultymedical educationorganizational efforthealth study sectionsnational institutesemergency medicine

Hands Free Pulse Checks: The Future of Cpr. Resuscitation (2024)

Willard W SharpDavid G Beiser

resuscitationcritical care

T32 Programs in Emergency Medicine: A Report From the Acep ‐ Saem Federal Research Funding Workgroup. Academic Emergency Medicine (2024)

Patrick J. MaherRichard RothmanRobert NeumarJeremy BrownWillard SharpCharles CairnsGabor D. KelenAmy KajiJody A. VogelLynne D. Richardson

emergency department administrationcritical emergency medicineemergency careemergency managementemergency medical servicespublic healthclinical researchemergency medicine

Abstract 211: Targeting the Mitochondrial Fission Protein Dynamin Related Protein 1 to Mitigate Oxygen Toxicity Following Cardiac Arrest. Circulation (2023)

Lin PiaoYong-hu FangRongxue Rosie WuRobert HamanakaGokhan MutluAlfredo J GarciaStephen L ArcherWillard Sharp

resuscitationcardiologyoxygen toxicityphysiologymitochondrial fission proteincardiac arresttoxicologyemergency medicine

Abstract P2127: A Novel Arnt Dependent Hif2A Singling in Protecting Against Cardiac Microvascular Endothelial Barrier Dysfunction Following Myocardial Infarction. Circulation Research (2023)

Karim Karim UllahLizhuo AiYan LiLifeng LiuKaichao PanZainab HumayunAlbert SitikovQiaozhu SuQiong ZhaoWillard W SharpYun FangDavid WuJames K LiaoRongxue R Wu

myocardial infarctionhematologycirculatory physiologyinflammationcardiologycardiovascular functioncardiovascular physiologyimmunologypharmacologyvascular biologyrespiratory medicinenephrologycardiovascular researchpreventive medicineendothelial dysfunctionhealth sciencescardiovascular diseasemicrovascular dysfunction

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Willard W. Sharp

Associate Professor of Medicine

University of Chicago

Affiliations

Pritzker School of Medicine

Medicine

Willard W. Sharp is currently serving as a Medicine Associate Professor of Medicine at University of Chicago.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Willard W. Sharp

University of Chicago

Associate Professor of Medicine

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Acute Ischemic Stroke in a Marathon Runner: Last Known Well at Mile 22 Case Report. Prehospital Emergency Care (2025)

Katie L. TatarisWillard W. SharpGeorge T. ChiampasAmeera S. Haamid

intensive careresuscitationstrokeemergency careacute ischemic strokeacute carecritical careprehospital caremarathon runneremergency medicine

Arnt-Dependent Hif-2α Signaling Protects Cardiac Microvascular Barrier Integrity and Heart Function Post-Myocardial Infarction. Communications Biology (2025)

Karim UllahLizhuo AiYan LiLifeng LiuQin ZhangKaichao PanZainab HumayunLin PiaoAlbert SitikovQiong ZhaoQiaozhu SuWillard SharpYun FangDavid WuJames K. LiaoRongxue Wu

myocardial infarctioncardiologycardiovascular functioncell signalingsystems biologybiologyvascular biologycardiovascular researchmolecular biologymicrovascular dysfunction

Divergent Ventilatory Responses During Opioid-Induced Respiratory Depression in Response to Repeated Fentanyl Use. American Journal of Physiology-Lung Cellular and Molecular Physiology (2025)

Karan G. RaiChinwendu U. NwakuduCaroline C. SzujewskiBrigitte M. BroweGia E. FisherWillard W. SharpAndrew K. TrybaAlfredo J. Garcia

pulmonary pharmacologyopioid-induced respiratory depressionsubstance use disordersdivergent ventilatory responsesrespiratory medicinephysiologyfentanyl usemolecular physiology

Rediscovery of Acute Lung Injury in Cardiac Arrest: Breathing Fresh Air Into a Neglected Component of the Post-Cardiac Arrest Syndrome. Resuscitation (2025)

Willard W SharpLin Piao

resuscitationcardiopulmonary resuscitationacute lung injurypost-cardiac arrest syndromebreathing fresh aircardiac arrestemergency medicine

A Novel Preclinical Model of Fentanyl-Induced Cardiorespiratory Collapse to Investigate Resuscitation Outcomes. Physiology (2024)

Lin PiaoYonghu FangAlfredo J. GarciaWillard Sharp

Assessment of an Organizational Effort to Increase Emergency Medicine Faculty on National Institutes of Health Study Sections. Academic Emergency Medicine (2024)

emergency medicine facultymedical educationorganizational efforthealth study sectionsnational institutesemergency medicine

Hands Free Pulse Checks: The Future of Cpr. Resuscitation (2024)

Willard W SharpDavid G Beiser

resuscitationcritical care

T32 Programs in Emergency Medicine: A Report From the Acep ‐ Saem Federal Research Funding Workgroup. Academic Emergency Medicine (2024)

Patrick J. MaherRichard RothmanRobert NeumarJeremy BrownWillard SharpCharles CairnsGabor D. KelenAmy KajiJody A. VogelLynne D. Richardson

emergency department administrationcritical emergency medicineemergency careemergency managementemergency medical servicespublic healthclinical researchemergency medicine

Abstract 211: Targeting the Mitochondrial Fission Protein Dynamin Related Protein 1 to Mitigate Oxygen Toxicity Following Cardiac Arrest. Circulation (2023)

Lin PiaoYong-hu FangRongxue Rosie WuRobert HamanakaGokhan MutluAlfredo J GarciaStephen L ArcherWillard Sharp

resuscitationcardiologyoxygen toxicityphysiologymitochondrial fission proteincardiac arresttoxicologyemergency medicine

Abstract P2127: A Novel Arnt Dependent Hif2A Singling in Protecting Against Cardiac Microvascular Endothelial Barrier Dysfunction Following Myocardial Infarction. Circulation Research (2023)

Karim Karim UllahLizhuo AiYan LiLifeng LiuKaichao PanZainab HumayunAlbert SitikovQiaozhu SuQiong ZhaoWillard W SharpYun FangDavid WuJames K LiaoRongxue R Wu

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