Faculty

Institution

Unit

Venue

Wayne Harding

Associate Professor

CUNY--Hunter College

Affiliations

Chemistry

Wayne Harding is currently serving as a Chemistry Associate Professor at Cuny--Hunter College.

Honors

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Experiences

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Education

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Wayne Harding

CUNY--Hunter College

Associate Professor

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pharmacology medicinal chemistry biochemistry chemical synthesis organic synthesis bioorganic chemistry natural products receptors medicine natural product research pharmacological research synthetic chemistry drug discovery organic process research biomolecular engineering medicinal research pharmaceutical chemistry phytochemistry natural product synthesis receptor (biochemistry) phytotherapy research organic chemistry frontier pharmacotherapy microwave synthesis phytochemicals mechanisms of action experimental pharmacology neoclerodane diterpenes salvia divinorum analytical chemistry coordination chemistry protein science transition metal chemistry clinical chemistry enzyme inhibition plant science polyhedron sustainable chemistry structural chemistry selective separation functional modification molecular docking colorectal cancer derivative (chemistry) synthesis methods non-peptide ligand enantioselective synthesis heterocycle chemistry heterocyclic opioid use disorder pharmacological agents pharmacokinetics phytopharmacology pharmacological studies herb-drug interactions secondary metabolites body fluids selective modification synthetic studies furan ring homology modeling molecular docking studies first application flexible congeners molecular modeling investigations acetylcholinesterase inhibitor enzyme kinetics sar study labdane diterpenes leonotis leonurus central nervous system neuropsychiatric disorders drug abuse

Notable Scholarly Works

Notable Federal Grants

Collaborators

Aporphinoid Antagonists of 5-Ht2A Receptors: Further Evaluation of Ring a Substituents and the Size of Ring C. Chem Biol Drug Des (2014)

aporphinoid antagonistsreceptors5-ht2a receptorsring creceptor (biochemistry)pharmacological researchmedicinal chemistrypharmacologymolecular pharmacologynon-peptide ligandmedicinal researchallergy

Evaluation of Structural Effects on 5-Ht(2A) Receptor Antagonism by Aporphines: Identification of a New Aporphine With 5-Ht(2A) Antagonist Activity. Bioorg. Med. Chem. Lett. (2014)

receptorsreceptor (biochemistry)pharmacological researchmechanisms of actionantagonist activityexperimental pharmacologybiochemistrypharmacologyreceptor antagonismtherapeutic targetsnew aporphinedrug discoverypharmacotherapy

A New Route to Azafluoranthene Natural Products via Direct Arylation. European J Org Chem (2013)

organic process researchsustainable chemistrychemistryorganic chemistrybiomolecular engineeringchemical synthesisnatural productsnew routesynthetic chemistrysynthesis methodsorganic synthesisnatural product researchnatural product synthesisorganic chemistry frontier

Facile Synthesis of 4,5,6A,7-Tetrahydrodibenzo[De,G]Chromene Heterocycles and Their Transformation to Phenanthrene Alkaloids. Tetrahedron (2013)

organic process researchheterocycle chemistrychemistryorganic chemistrychemical synthesischromene heterocyclessynthetic chemistryorganic synthesispharmacologyfacile synthesisheterocyclicstructural chemistry

Leonurenones a–C: Labdane Diterpenes From Leonotis Leonurus. Phytochemistry (2012)

Fang HeCharlotte LindqvistWayne W. Harding

chemistrynatural productsbotanyphytochemistrylabdane diterpenesplant sciencephytochemicalsleonotis leonurus

Cytotoxicity of Aporphines in Human Colon Cancer Cell Lines Hct-116 and Caco-2: An Sar Study. Bioorganic & Medicinal Chemistry Letters (2011)

Shashikanth PonnalaSandeep ChaudharyAntonio González-SarriasNavindra P. SeeramWayne W. Harding

colorectal cancermedicineoncologymedicinal chemistrybioorganic chemistrybiochemistrypharmacologysar study

New Aporphinoid 5-Ht2A and 1A Antagonists via Structural Manipulations of Nantenine. Bioorg Med Chem (2011)

new aporphinoidreceptorsstructural manipulationsreceptor (biochemistry)neuropharmacologypharmacological researchmechanisms of actionbiochemistrypharmacologymolecular pharmacologypharmacotherapymedicinal research

Affinity of Aporphines for the Human 5-Ht2A Receptor: Insights From Homology Modeling and Molecular Docking Studies. Bioorganic & Medicinal Chemistry (2010)

Stevan PecicPooja MakkarSandeep ChaudharyBoojala V. ReddyHernan A. NavarroWayne W. Harding

receptorsmedicinemolecular docking studiesmedicinal chemistrymolecular dockingbioorganic chemistrybiochemistrypharmacologyhomology modelingdrug discovery

Nantenine as an Acetylcholinesterase Inhibitor: Sar, Enzyme Kinetics and Molecular Modeling Investigations. Journal of Enzyme Inhibition and Medicinal Chemistry (2010)

Stevan PecicMarie A. McAnuffWayne W. Harding

medicineacetylcholinesterase inhibitormolecular modeling investigationsmedicinal chemistrypharmacologyenzyme inhibitionenzyme kinetics

Synthesis of C-Homoaporphines via Microwave-Assisted Direct Arylation. Tetrahedron (2010)

Sandeep ChaudharyWayne W. Harding

microwave synthesischemical synthesismicrowave-assisted direct arylationpolyhedronbiochemistryorganic synthesis

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Wayne Harding

Associate Professor

CUNY--Hunter College

Affiliations

Chemistry

Wayne Harding is currently serving as a Chemistry Associate Professor at Cuny--Hunter College.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Wayne Harding

CUNY--Hunter College

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Aporphinoid Antagonists of 5-Ht2A Receptors: Further Evaluation of Ring a Substituents and the Size of Ring C. Chem Biol Drug Des (2014)

aporphinoid antagonistsreceptors5-ht2a receptorsring creceptor (biochemistry)pharmacological researchmedicinal chemistrypharmacologymolecular pharmacologynon-peptide ligandmedicinal researchallergy

Evaluation of Structural Effects on 5-Ht(2A) Receptor Antagonism by Aporphines: Identification of a New Aporphine With 5-Ht(2A) Antagonist Activity. Bioorg. Med. Chem. Lett. (2014)

A New Route to Azafluoranthene Natural Products via Direct Arylation. European J Org Chem (2013)

Facile Synthesis of 4,5,6A,7-Tetrahydrodibenzo[De,G]Chromene Heterocycles and Their Transformation to Phenanthrene Alkaloids. Tetrahedron (2013)

Leonurenones a–C: Labdane Diterpenes From Leonotis Leonurus. Phytochemistry (2012)

Fang HeCharlotte LindqvistWayne W. Harding

chemistrynatural productsbotanyphytochemistrylabdane diterpenesplant sciencephytochemicalsleonotis leonurus

Cytotoxicity of Aporphines in Human Colon Cancer Cell Lines Hct-116 and Caco-2: An Sar Study. Bioorganic & Medicinal Chemistry Letters (2011)

Shashikanth PonnalaSandeep ChaudharyAntonio González-SarriasNavindra P. SeeramWayne W. Harding

colorectal cancermedicineoncologymedicinal chemistrybioorganic chemistrybiochemistrypharmacologysar study

New Aporphinoid 5-Ht2A and 1A Antagonists via Structural Manipulations of Nantenine. Bioorg Med Chem (2011)

Affinity of Aporphines for the Human 5-Ht2A Receptor: Insights From Homology Modeling and Molecular Docking Studies. Bioorganic & Medicinal Chemistry (2010)

Stevan PecicPooja MakkarSandeep ChaudharyBoojala V. ReddyHernan A. NavarroWayne W. Harding

receptorsmedicinemolecular docking studiesmedicinal chemistrymolecular dockingbioorganic chemistrybiochemistrypharmacologyhomology modelingdrug discovery

Nantenine as an Acetylcholinesterase Inhibitor: Sar, Enzyme Kinetics and Molecular Modeling Investigations. Journal of Enzyme Inhibition and Medicinal Chemistry (2010)

Stevan PecicMarie A. McAnuffWayne W. Harding

medicineacetylcholinesterase inhibitormolecular modeling investigationsmedicinal chemistrypharmacologyenzyme inhibitionenzyme kinetics

Synthesis of C-Homoaporphines via Microwave-Assisted Direct Arylation. Tetrahedron (2010)

Sandeep ChaudharyWayne W. Harding

microwave synthesischemical synthesismicrowave-assisted direct arylationpolyhedronbiochemistryorganic synthesis

1
2
10 / page