Faculty

Institution

Unit

Venue

Wade Gibson

Professor

Johns Hopkins University

Affiliations

School of Medicine

Pharmacology & Molecular Sciences

Wade Gibson is currently serving as a Pharmacology & Molecular Sciences Professor at Johns Hopkins University.

Honors

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Experiences

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Education

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Wade Gibson

Johns Hopkins University

Professor

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virology epidemiology molecular biology virus research viral genetics molecular virology viral evolution cell biology structural biology human cytomegalovirus gene expression virus-host interactions biochemistry protein science general virology protein assembly mammalian biology virus transmission avian biology toxicology virus structure viral structural protein inhalation toxicology food toxicology major capsid protein simian cytomegalovirus cytomegalovirus assemblin enzymes membrane biology protein structure proteomics biological chemistry g protein-coupled receptor viral replication protein phosphorylation protein expression herpesvirus maturational proteinase virus particles virion proteins cytomegalovirus-infected cells proteinase precursor virus production proteolytic activity stem cell research bone research redox biology vascular biology liver physiology clinical microbiology computational imaging machine vision biomedical imaging additive manufacturing multiple scale real world evidence sample introduction intermediate representation abstract interpretation viral diagnostics nuclear organization integrative biology molecular basis molecular evidence genetic basis venomics rna biology protein transport host specificity drug development virus gene gene function multiple forms multiple capsid forms human strains noninfectious virion-like particle major polypeptides

Notable Scholarly Works

Notable Federal Grants

Collaborators

Nelfinavir Inhibits Maturation and Export of Herpes Simplex Virus 1. Journal of Virology (2014)

Nene N. KaluPrashant J. DesaiCourtney M. ShirleyWade GibsonPhillip A. DennisRichard F. Ambinder

gene expressionvirus-host interactionsepidemiologygeneral virologyvirologyviral evolutionvirus transmission

Recovery of an Hmwp/Hmwbp (Pul48/Pul47) Complex From Virions of Human Cytomegalovirus: Subunit Interactions, Oligomer Composition, and Deubiquitylase Activity. Journal of Virology (2014)

Jennifer A. TullmanMary-Elizabeth HarmonMichael DelannoyWade Gibson

oligomer compositionvirus-host interactionsepidemiologygene vectorsubunit interactionsvirologyviral evolutionhuman cytomegalovirusvirus transmissiondeubiquitylase activity

Cytomegalovirus Assemblin and Precursor. Handbook of Proteolytic Enzymes (2012)

Wade Gibson

virologymicrobiologyvirus phylogenycytomegalovirus assemblin

Cytomegalovirus Capsid Protease: Biological Substrates Are Cleaved More Efficiently by Full-Length Enzyme (Pul80A) Than by the Catalytic Domain (Assemblin). Journal of Virology (2011)

Steve M. FernandesEdward J. BrignoleKanchan TaoriWade Gibson

immunologyfull-length enzymecatalytic domainvirologybiological substratescytomegalovirus capsid protease

Cleavage Specificity of the Ul48 Deubiquitinating Protease Activity of Human Cytomegalovirus and the Growth of an Active-Site Mutant Virus in Cultured Cells. Journal of Virology (2009)

Eui Tae KimSe Eun OhYun-Ok LeeWade GibsonJin-Hyun Ahn

epidemiologyactive-site mutant virushost specificitymolecular virologycleavage specificityvirologyhuman cytomegaloviruscultured cellscell biology

Nuclear Localization Sequences in Cytomegalovirus Capsid Assembly Proteins (Ul80 Proteins) Are Required for Virus Production: Inactivating Nls1, Nls2, or Both Affects Replication to Strikingly Different Extents. Journal of Virology (2008)

Nang L. NguyenAmy N. LovelandWade Gibson

nuclear localization sequencesepidemiologyvirus productionvirologymolecular biologyviral replication

Structure and Formation of the Cytomegalovirus Virion. Current topics in microbiology and immunology (2008)

W. Gibson

immunologyvirus structureepidemiologyvirologyviral evolutionstructural biologymicrobiologycytomegalovirus virion

Enzymatic Activities of Human Cytomegalovirus Maturational Protease Assemblin and Its Precursor (Ppr, Pul80A) Are Comparable: Maximal Activity of Ppr Requires Self-Interaction Through Its Scaffolding Domain. Journal of Virology (2007)

Edward J. BrignoleWade Gibson

protein functionenzymatic activitiesgeneral virologyprotein structurecell biologyvirus-host interactionsmolecular virologyviral geneticsenzymesprotein sciencemedical virologyprotein engineeringimmunologyvirus researchgene expressionenzyme inhibitionvirologymolecular biologyprotein expressionscaffolding domainmaximal activity

High-Molecular-Weight Protein (Pul48) of Human Cytomegalovirus is a Competent Deubiquitinating Protease: Mutant Viruses Altered in Its Active-Site Cysteine or Histidine Are Viable. Journal of Virology (2006)

Jianlei WangAmy N. LovelandLisa M. KattenhornHidde L. PloeghWade Gibson

virus researchepidemiologymolecular virologyvirologyviral evolutionhuman cytomegalovirusmutant viruseshigh-molecular-weight proteinactive-site cysteine

The Amino-Conserved Domain of Human Cytomegalovirus Ul80A Proteins is Required for Key Interactions During Early Stages of Capsid Formation and Virus Production. Journal of Virology (2006)

Amy N. LovelandNang L. NguyenEdward J. BrignoleWade Gibson

early stagesepidemiologyamino-conserved domainvirus productionvirologymolecular biologycapsid formation

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Wade Gibson

Professor

Johns Hopkins University

Affiliations

School of Medicine

Pharmacology & Molecular Sciences

Wade Gibson is currently serving as a Pharmacology & Molecular Sciences Professor at Johns Hopkins University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Wade Gibson

Johns Hopkins University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Nelfinavir Inhibits Maturation and Export of Herpes Simplex Virus 1. Journal of Virology (2014)

Nene N. KaluPrashant J. DesaiCourtney M. ShirleyWade GibsonPhillip A. DennisRichard F. Ambinder

gene expressionvirus-host interactionsepidemiologygeneral virologyvirologyviral evolutionvirus transmission

Recovery of an Hmwp/Hmwbp (Pul48/Pul47) Complex From Virions of Human Cytomegalovirus: Subunit Interactions, Oligomer Composition, and Deubiquitylase Activity. Journal of Virology (2014)

Jennifer A. TullmanMary-Elizabeth HarmonMichael DelannoyWade Gibson

oligomer compositionvirus-host interactionsepidemiologygene vectorsubunit interactionsvirologyviral evolutionhuman cytomegalovirusvirus transmissiondeubiquitylase activity

Cytomegalovirus Assemblin and Precursor. Handbook of Proteolytic Enzymes (2012)

Wade Gibson

virologymicrobiologyvirus phylogenycytomegalovirus assemblin

Cytomegalovirus Capsid Protease: Biological Substrates Are Cleaved More Efficiently by Full-Length Enzyme (Pul80A) Than by the Catalytic Domain (Assemblin). Journal of Virology (2011)

Steve M. FernandesEdward J. BrignoleKanchan TaoriWade Gibson

immunologyfull-length enzymecatalytic domainvirologybiological substratescytomegalovirus capsid protease

Cleavage Specificity of the Ul48 Deubiquitinating Protease Activity of Human Cytomegalovirus and the Growth of an Active-Site Mutant Virus in Cultured Cells. Journal of Virology (2009)

Eui Tae KimSe Eun OhYun-Ok LeeWade GibsonJin-Hyun Ahn

epidemiologyactive-site mutant virushost specificitymolecular virologycleavage specificityvirologyhuman cytomegaloviruscultured cellscell biology

Nang L. NguyenAmy N. LovelandWade Gibson

nuclear localization sequencesepidemiologyvirus productionvirologymolecular biologyviral replication

Structure and Formation of the Cytomegalovirus Virion. Current topics in microbiology and immunology (2008)

W. Gibson

immunologyvirus structureepidemiologyvirologyviral evolutionstructural biologymicrobiologycytomegalovirus virion

Edward J. BrignoleWade Gibson

Jianlei WangAmy N. LovelandLisa M. KattenhornHidde L. PloeghWade Gibson

virus researchepidemiologymolecular virologyvirologyviral evolutionhuman cytomegalovirusmutant viruseshigh-molecular-weight proteinactive-site cysteine

The Amino-Conserved Domain of Human Cytomegalovirus Ul80A Proteins is Required for Key Interactions During Early Stages of Capsid Formation and Virus Production. Journal of Virology (2006)

Amy N. LovelandNang L. NguyenEdward J. BrignoleWade Gibson

early stagesepidemiologyamino-conserved domainvirus productionvirologymolecular biologycapsid formation

1
2
3
4
5
8
10 / page