Faculty

Institution

Unit

Venue

Vivek K. Unni, M.D., Ph.D.

Oregon Health & Science University

Affiliations

Biostatistics Shared Resources

Institute Of Knight Cancer

OHSU School of Medicine

Cancer Early Detection Advanced Research Center (Cedar)

Department Of Cell, Developmental And Cancer Biology

Department Of Pediatrics

Division Of Oncological Sciences

Center Of Cancer Early Detection Advanced Research (Cedar)

Institute Of Knight Cancer

Center Of Knight Cancer

Department of Medicine

Division Of Hematology/Medical Oncology

Department Of Pediatrics

Division Of Neurology

Flow Cytometry Shared Resource

Institute Of Knight Cancer

Cancer Early Detection Advanced Research Center (Cedar)

Institute Of Knight Cancer

Division Of Oncological Sciences

Institute Of Knight Cancer

Department Of Cell, Developmental And Cancer Biology

Institute Of Knight Cancer

Division Of Hematology/Medical Oncology

Institute Of University Knight Cancer

Jungers Center For Neurosciences Research

Oregon Health & Science University

NoneVivek K. Unni, M.d., Ph.d. is currently serving as a Biostatistics Shared Resources faculty at Oregon Health & Science University.

Honors

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Experiences

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Education

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Vivek K. Unni, M.D., Ph.D.

Oregon Health & Science University

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neuroscience neurodegenerative diseases molecular neurodegeneration parkinson's disease degenerative pathology neurology cell biology molecular neuroscience degenerative disease genetics molecular neurobiology dna repair neurogenetics neuroscience of aging movement disorders molecular cell biology cellular neurobiology protein misfolding mouse model neuropathology mammalian biology autophagy clinical neuroscience experimental neuropathology neuroinflammation knockout mice genome instability neuroanatomy neurons protein science brain tumor research vascular biology nucleic acids biomedical imaging sex-dependent manner proteome research neurosurgery medicinal research experimental medicine biological chemistry protein function key site cancer genetics neural science neurotransmission brain pathology tissue imaging brain imaging intracellular trafficking brain mapping novel imaging methods neuroregeneration auto-tuning genetic disorders protein genetics neurological disorders neuroimaging biomarkers osmoregulation molecular microbiology protein transport cell trafficking radiation biology autophagy-lysosomal pathway ubiquitin-proteasome system distinct roles altered phosphate export lewy body disorders progressive aggregation lewy inclusion-bearing neurons selective degeneration alpha-synuclein mouse model retrograde axonal spread lewy pathology pre-formed fibril injection mouse cortex stable expression translational research pediatric urology child neurology molecular psychiatry pediatrics medicine rheumatology diagnosis neurodevelopmental disorders huntington's disease scleroderma

Notable Scholarly Works

Notable Federal Grants

Collaborators

0417 Preclinical Model to Test Potential Therapeutics to Prevent Phenoconversion of Rem Sleep Behavior Disorder to Parkinson’s Disease After Neurotrauma. SLEEP (2025)

neurologypharmacologypsychopharmacologypreclinical modelparkinson's diseaseclinical neuroscienceneuropharmacologysleepsleep disorderstranslational psychiatrymovement disordersmolecular neurodegenerationtest potential therapeuticsprevent phenoconversionneuroscienceneurodegenerative diseases

Alpha-Synuclein Knockout Impairs Melanoma Development and Alters Dna Damage Repair in the Tg3 Mouse Model in a Sex-Dependent Manner. Frontiers in Oncology (2025)

carcinogenesisdevelopmental biologygerm cellssex-dependent mannertg3 mouse modelknockout micemolecular neurodegenerationdna repairneurodegenerative diseasescell biology

Alpha-Synuclein Regulates Nucleolar Dna Double-Strand Break Repair in Melanoma. Science Advances (2025)

carcinogenesismelanomamolecular cancermolecular cell biologyphotocarcinogenesisnucleic acidsmolecular biologymolecular neurodegenerationoncogenesdna repairdna replicationgenome instabilitycell biology

The Christchurch Point Mutation in Mouse Apoe Reduces Aβ-Induced Tau and α-Synuclein Pathologies. bioRxiv (Cold Spring Harbor Laboratory) (2025)

mouse apoeprotein misfoldingparkinson's diseasemolecular neuroscienceaβ-induced tauknockout micemolecular biologymolecular neurodegenerationdegenerative pathologydegenerative diseasealzheimer's diseasemutagenesis (molecular biology technique)neurodegenerative diseaseschristchurch point mutationcell biology

Alpha-Synuclein Modulates the Repair of Genomic Dna Double-Strand Breaks in a Dna-Pkcs-Regulated Manner. Neurobiology of Disease (2024)

dna-pkcs-regulated mannerparkinson's diseasegeneticsmolecular cell biologymolecular biologymolecular neurodegenerationdegenerative pathologydegenerative diseasedna repairneurodegenerative diseasesgenome instabilitycell biology

Alpha-Synuclein Regulates the Repair of Genomic Dna Double-Strand Breaks in a Dna-Pk Cs -Dependent Manner. bioRxiv (Cold Spring Harbor Laboratory) (2024)

parkinson's diseasegeneticsmolecular cell biologymolecular biologymolecular geneticsmolecular neurodegenerationdegenerative pathologydna repairdegenerative diseaseneurodegenerative diseasesgenome instabilitycell biology

Aquaporin-4 Mis-Localization Slows Glymphatic Clearance of α-Synuclein and Promotes α-Synuclein Pathology and Aggregate Propagation. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Molly BraunMatthew J SimonJay JangKeith SandersonJustyna SwierzMathew SevaoAlexandra B PincusAllison J SchaserJonathan E ElliottMiranda M LimVivek K UnniAbigail G SchindlerC. Dirk KeeneCaitlin S LatimerJeffrey Iliff

pathogenesisosmoregulationcell signalingdegenerative pathologymolecular microbiologyvascular biologyprotein transportmolecular cell biologymembrane biologyneurodegenerative diseasesnucleic acidscell traffickingaggregate propagationmembrane proteinsmolecular neurodegenerationglymphatic clearanceimmunologymicrobiologybrain tumor researcha-synuclein pathologyneuroscience

Association of Melanoma and Incidence of Parkinson’s Disease: A Cohort Study in Us Veterans. Innovation in Aging (2024)

melanomaepidemiologyparkinson's diseaseskin cancerhealth sciences

Effects of Paraquat, Dextran Sulfate Sodium, and Irradiation on Behavioral and Cognitive Performance and the Gut Microbiome in A53T and A53T-L444P Mice. Genes (2024)

Ariel ChaklaiAbigail O’NeilShrey GoelNick MargoliesDestine KrenikRuby PerezKat KesslerElizabeth StaltontallHong Ki (Eric) YoonMontzerrat PantojaKeaton StagamanKristin KasschauVivek UnniRobert DuvoisinThomas SharptonJacob Raber

microbiomegene therapygenomicsgene expressiondextran sulfate sodiumradiation oncologyradiation biologygeneticsmammalian biologygene functionradiationgut microbiomeneurosciencecognitive performance

Polo-Like Kinase Inhibition Leads to Neuroprotection of Neurons Bearing Alpha-Synuclein Lewy Body-Like Inclusions in Vivo. PubMed (2024)

cell signalingparkinson's diseasemolecular neuroscienceneuroprotectionmolecular neurobiologypolo-like kinase inhibitionexperimental neuropathologydegenerative pathologymolecular neurodegenerationdegenerative diseaseautophagyneuroscienceneurodegenerative diseasescell biology

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Vivek K. Unni, M.D., Ph.D.

Oregon Health & Science University

Affiliations

Biostatistics Shared Resources

Institute Of Knight Cancer

OHSU School of Medicine

Cancer Early Detection Advanced Research Center (Cedar)

Department Of Cell, Developmental And Cancer Biology

Department Of Pediatrics

Division Of Oncological Sciences

Center Of Cancer Early Detection Advanced Research (Cedar)

Institute Of Knight Cancer

Center Of Knight Cancer

Department of Medicine

Division Of Hematology/Medical Oncology

Department Of Pediatrics

Division Of Neurology

Flow Cytometry Shared Resource

Institute Of Knight Cancer

Cancer Early Detection Advanced Research Center (Cedar)

Institute Of Knight Cancer

Division Of Oncological Sciences

Institute Of Knight Cancer

Department Of Cell, Developmental And Cancer Biology

Institute Of Knight Cancer

Division Of Hematology/Medical Oncology

Institute Of University Knight Cancer

Jungers Center For Neurosciences Research

Oregon Health & Science University

NoneVivek K. Unni, M.d., Ph.d. is currently serving as a Biostatistics Shared Resources faculty at Oregon Health & Science University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Vivek K. Unni, M.D., Ph.D.

Oregon Health & Science University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

0417 Preclinical Model to Test Potential Therapeutics to Prevent Phenoconversion of Rem Sleep Behavior Disorder to Parkinson’s Disease After Neurotrauma. SLEEP (2025)

Alpha-Synuclein Knockout Impairs Melanoma Development and Alters Dna Damage Repair in the Tg3 Mouse Model in a Sex-Dependent Manner. Frontiers in Oncology (2025)

carcinogenesisdevelopmental biologygerm cellssex-dependent mannertg3 mouse modelknockout micemolecular neurodegenerationdna repairneurodegenerative diseasescell biology

Alpha-Synuclein Regulates Nucleolar Dna Double-Strand Break Repair in Melanoma. Science Advances (2025)

The Christchurch Point Mutation in Mouse Apoe Reduces Aβ-Induced Tau and α-Synuclein Pathologies. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Alpha-Synuclein Modulates the Repair of Genomic Dna Double-Strand Breaks in a Dna-Pkcs-Regulated Manner. Neurobiology of Disease (2024)

Alpha-Synuclein Regulates the Repair of Genomic Dna Double-Strand Breaks in a Dna-Pk Cs -Dependent Manner. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Aquaporin-4 Mis-Localization Slows Glymphatic Clearance of α-Synuclein and Promotes α-Synuclein Pathology and Aggregate Propagation. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Association of Melanoma and Incidence of Parkinson’s Disease: A Cohort Study in Us Veterans. Innovation in Aging (2024)

melanomaepidemiologyparkinson's diseaseskin cancerhealth sciences

Effects of Paraquat, Dextran Sulfate Sodium, and Irradiation on Behavioral and Cognitive Performance and the Gut Microbiome in A53T and A53T-L444P Mice. Genes (2024)

microbiomegene therapygenomicsgene expressiondextran sulfate sodiumradiation oncologyradiation biologygeneticsmammalian biologygene functionradiationgut microbiomeneurosciencecognitive performance

Polo-Like Kinase Inhibition Leads to Neuroprotection of Neurons Bearing Alpha-Synuclein Lewy Body-Like Inclusions in Vivo. PubMed (2024)

1
2
3
4
10 / page