Faculty

Institution

Unit

Venue

Vincent Hilser

Professor and Chair Department of Biology

Johns Hopkins University

Affiliations

Natural Sciences

Chemistry-Biology Interface Program

Department of Biology

Department of Biophysics

Program in Cell, Molecular, Development Biology, and Biophysics

Program in Molecular Biophysics

Krieger School of Arts and Sciences

Natural Sciences

Vincent Hilser is currently serving as a Chemistry-Biology Interface Program Professor and Chair Department of Biology at Johns Hopkins University.

Honors

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Experiences

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Education

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Vincent Hilser

Johns Hopkins University

Professor and Chair Department of Biology

You can click a keyword to filter the displayed items

biophysics protein science structural biology molecular biology biochemistry protein structure protein folding molecular biophysics enzymes structural molecular biology evolutionary biology membrane biology thermodynamics protein engineering protein evolution molecular physiology biophysical review conformational studies protein chemistry protein function theoretical biology protein phosphorylation native state ensemble polyproline ii intrinsic disorder biomolecular interactions structural bioinformatics phase separation glucocorticoid receptor nature bioenergetics molecular science redox biology protein modeling enzyme catalysis protein misfolding protein bioinformatics allosteric coupling cooperative interactions local conformational fluctuations conformational fluctuations cold denaturation allosteric ensembles native state thermodynamic mechanism ensemble modulation capillary zone electrophoresis ensemble allosteric model mitotic function biochemical sciences biological chemistry cellular physiology psychoneuroendocrinology wildlife forest ecology water science medical biophysics structural composition structural morphology structure-function enzyme kinetics molecular regulation protein mass spectrometry data exchange capillary electrophoresis behavioural physiology behavioral neuroendocrinology philosophy of biology biomedical research cancer biology surface-water hydrology terrestrial ecology surface runoff environmental geology drylands signal recognition signaling pathways

Notable Scholarly Works

Notable Federal Grants

Collaborators

Statistical Thermodynamics of the Protein Ensemble: Mediating Function and Evolution. Annual Review of Biophysics (2025)

biophysical reviewstructural molecular biologytheoretical biologymolecular biologymolecular scienceprotein foldingprotein engineeringbiophysical chemistryprotein sciencebiomolecular structuresystems biologyprotein designmolecular modellingprotein structurestatistical mechanicsmolecular biophysicsbiophysics

Cest Nmr Characterization of Functional Domain Unfolding in Adenylate Kinase. Biophysical Journal (2024)

Sarah J. BrantleyMiranda RussoAnanya K. MajumdarVincent J. Hilser

cell biologyfunctional domain unfoldingcest nmr characterizationstructural biologyprotein foldingprotein scienceneurosciencenuclear magnetic resonanceadenylate kinasebiophysics

Ensemble-Based Energetic Differences Between Protein Data Bank Structures and Alphafold2 Models. Biophysical Journal (2024)

James O. WrablMartin HilserVincent J. Hilser

ensemble-based energetic differencesstructural biologybiophysics

Impact of Environmental Factors on a Metamorphic Protein. Biophysical Journal (2024)

Marie PearceVincent J. Hilser

structural biologymetamorphic proteinmetamorphismenvironmental sciencebiophysics

Negative Inter-Domain Coupling in E. Coli Adenylate Kinase. Biophysical Journal (2024)

Anna AndrickMiranda RussoSarah J. BrantleyAnanya K. MajumdarVincent J. Hilser

biochemistrynegative inter-domain couplingstructural biologybiophysical chemistrypharmacologyprotein sciencemolecular biophysicsbiophysics

The Variable Domain From Dynamin‐Related Protein 1 Promotes Liquid–Liquid Phase Separation That Enhances Its Interaction With Cardiolipin‐Containing Membranes. Protein Science (2023)

Ammon E. PoseyKyle A. RossMehran BagheriElizabeth N. LanumMisha A. KhanChristine E. JenningsMegan C. HarwigNolan W. KennedyVincent J. HilserJames L. HardenR. Blake Hill

structural biologyliquid-liquid phase separationbiomolecular engineeringprotein engineeringprotein sciencebiomedical engineeringcardiolipin-containing membranesprotein structurebiomolecular interactionsvariable domainbiophysics

The Variable Domain From the Mitochondrial Fission Mechanoenzyme Drp1 Promotes Liquid-Liquid Phase Separation. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Ammon E. PoseyMehran BagheriKyle A. RossElizabeth N. LanumMisha A. KhanChristine M. JenningsMegan C. HarwigNolan W. KennedyVincent J. HilserJames L. HardenR. Blake Hill

membrane biologymolecular biologystructural biologyliquid-liquid phase separationphase separationprotein structurevariable domainbiological engineeringbiophysics

A Thermodynamic Atlas of Proteomes Reveals Energetic Innovation Across the Tree of Life. Molecular Biology and Evolution (2022)

Alexander F ChinJames O WrablVincent J Hilser

molecular evolutionmolecular biologythermodynamic atlasbiological evolutionevolutionary biologythermodynamicsproteomicsbiophysics

Phylogenetic Convergence of Phase Separation and Mitotic Function in the Disordered Protein Bugz. Protein Science (2022)

Alexander F. ChinYixian ZhengVincent J. Hilser

molecular biologystructural biologymitotic functionevolutionary biologyprotein sciencephase separationphylogenetic convergenceprotein structurephylogeneticsbiophysics

A Predictive Energy Landscape Model of Metamorphic Protein Conformational Specificity. bioRxiv (Cold Spring Harbor Laboratory) (2021)

James O. WrablKeila Voortman-SheetzVincent J. Hilser

biophysicsstructural biologysystems biologyprotein sciencesynthetic biologymetamorphismstructural bioinformaticsbiological engineering

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Vincent Hilser

Professor and Chair Department of Biology

Johns Hopkins University

Affiliations

Natural Sciences

Chemistry-Biology Interface Program

Department of Biology

Department of Biophysics

Program in Cell, Molecular, Development Biology, and Biophysics

Program in Molecular Biophysics

Krieger School of Arts and Sciences

Natural Sciences

Vincent Hilser is currently serving as a Chemistry-Biology Interface Program Professor and Chair Department of Biology at Johns Hopkins University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Vincent Hilser

Johns Hopkins University

Professor and Chair Department of Biology

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Statistical Thermodynamics of the Protein Ensemble: Mediating Function and Evolution. Annual Review of Biophysics (2025)

Cest Nmr Characterization of Functional Domain Unfolding in Adenylate Kinase. Biophysical Journal (2024)

Sarah J. BrantleyMiranda RussoAnanya K. MajumdarVincent J. Hilser

cell biologyfunctional domain unfoldingcest nmr characterizationstructural biologyprotein foldingprotein scienceneurosciencenuclear magnetic resonanceadenylate kinasebiophysics

Ensemble-Based Energetic Differences Between Protein Data Bank Structures and Alphafold2 Models. Biophysical Journal (2024)

James O. WrablMartin HilserVincent J. Hilser

ensemble-based energetic differencesstructural biologybiophysics

Impact of Environmental Factors on a Metamorphic Protein. Biophysical Journal (2024)

Marie PearceVincent J. Hilser

structural biologymetamorphic proteinmetamorphismenvironmental sciencebiophysics

Negative Inter-Domain Coupling in E. Coli Adenylate Kinase. Biophysical Journal (2024)

Anna AndrickMiranda RussoSarah J. BrantleyAnanya K. MajumdarVincent J. Hilser

biochemistrynegative inter-domain couplingstructural biologybiophysical chemistrypharmacologyprotein sciencemolecular biophysicsbiophysics

The Variable Domain From Dynamin‐Related Protein 1 Promotes Liquid–Liquid Phase Separation That Enhances Its Interaction With Cardiolipin‐Containing Membranes. Protein Science (2023)

Ammon E. PoseyKyle A. RossMehran BagheriElizabeth N. LanumMisha A. KhanChristine E. JenningsMegan C. HarwigNolan W. KennedyVincent J. HilserJames L. HardenR. Blake Hill

The Variable Domain From the Mitochondrial Fission Mechanoenzyme Drp1 Promotes Liquid-Liquid Phase Separation. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Ammon E. PoseyMehran BagheriKyle A. RossElizabeth N. LanumMisha A. KhanChristine M. JenningsMegan C. HarwigNolan W. KennedyVincent J. HilserJames L. HardenR. Blake Hill

membrane biologymolecular biologystructural biologyliquid-liquid phase separationphase separationprotein structurevariable domainbiological engineeringbiophysics

A Thermodynamic Atlas of Proteomes Reveals Energetic Innovation Across the Tree of Life. Molecular Biology and Evolution (2022)

Alexander F ChinJames O WrablVincent J Hilser

molecular evolutionmolecular biologythermodynamic atlasbiological evolutionevolutionary biologythermodynamicsproteomicsbiophysics

Phylogenetic Convergence of Phase Separation and Mitotic Function in the Disordered Protein Bugz. Protein Science (2022)

Alexander F. ChinYixian ZhengVincent J. Hilser

molecular biologystructural biologymitotic functionevolutionary biologyprotein sciencephase separationphylogenetic convergenceprotein structurephylogeneticsbiophysics

A Predictive Energy Landscape Model of Metamorphic Protein Conformational Specificity. bioRxiv (Cold Spring Harbor Laboratory) (2021)

James O. WrablKeila Voortman-SheetzVincent J. Hilser

biophysicsstructural biologysystems biologyprotein sciencesynthetic biologymetamorphismstructural bioinformaticsbiological engineering

1
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3
4
5
12
10 / page