Faculty

Institution

Unit

Venue

Victor R. DeFilippis

Oregon Health & Science University

Affiliations

Biostatistics Shared Resources

Institute Of Knight Cancer

OHSU School of Medicine

Cancer Early Detection Advanced Research Center (Cedar)

Department Of Cell, Developmental And Cancer Biology

Division Of Oncological Sciences

Center For Experimental Therapeutics

Center Of Cancer Early Detection Advanced Research (Cedar)

Institute Of Knight Cancer

Center Of Knight Cancer

Department of Medicine

Division Of Hematology/Medical Oncology

Division Of Pathobiology And Immunology

Flow Cytometry Shared Resource

Institute Of Knight Cancer

Cancer Early Detection Advanced Research Center (Cedar)

Institute Of Knight Cancer

Division Of Oncological Sciences

Institute Of Knight Cancer

Department Of Cell, Developmental And Cancer Biology

Institute Of Knight Cancer

Division Of Hematology/Medical Oncology

Institute Of Knight Cancer Insitute

Institute Of University Knight Cancer

OHSU Knight Cancer Institute

Oregon Health & Science University

NoneVictor R. Defilippis is currently serving as a Biostatistics Shared Resources faculty at Oregon Health & Science University.

Honors

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Experiences

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Education

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Victor R. DeFilippis

Oregon Health & Science University

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virology virus research immunology infectious diseases medical virology viral pathogenesis general virology molecular virology immune responses virus-host interactions antiviral research pathogenesis cell biology medicine antiviral responses immunity (medicine) medicinal research viral genetics vaccines viral replication infectious diseases (medical specialty) arbovirus vaccine development innate immune system pathogens vascular biology interferon response sars-cov-2 molecular cell biology cell death neglected tropical diseases cell research clinical microbiology cell transplantation clinical transplantation virus transmission viral oncology human retrovirus transplant arteriopathy heart transplantation viral persistence vaccine design host response human cytomegalovirus viral colonization lateral gene transfer avian biology avian medicine mammalian biology pathogen effector inhibitory activity parasite genomics pathogen detection pathogen characterization angiogenesis blood cells endothelial dysfunction viral evolution cell motility pathogen transmission virus epidemiology infectious disease modelling neovascularization immune dysregulation unfolded protein response placental dysfunction pregnant rhesus macaques cytomegalovirus immune evasion chikungunya virus antiviral activity anti-viral immunity aged rhesus macaques persistent viral replication endothelial cells rig-i agonists sequence-specific modifications

Notable Scholarly Works

Notable Federal Grants

Collaborators

Characterization of a Transmembrane-Activating Sting Agonist Using Genetically Humanized Mice. Cell Reports (2026)

receptorsreceptor (biochemistry)cell physiologycell biologycell signalingexperimental pharmacologymembrane biologysignal transductioncellular physiologycellular biochemistry

A Zika Virus-Like Particle Vaccine Mitigates Early Pregnancy Loss in Rhesus Macaques. bioRxiv (Cold Spring Harbor Laboratory) (2025)

maternal immunizationvaccinationvirologyvaccinesrhesus macaquesvaccine developmentreproductive immunologyinfectious diseasesmedical virologymaternal healthinfectious diseases (medical specialty)vaccine research

Characterization of a Novel Transmembrane Activating Sting Agonist Using Genetically Humanized Mice. bioRxiv (Cold Spring Harbor Laboratory) (2025)

receptorsgenetically humanized micereceptor (biochemistry)pharmacological researchmechanisms of actionmedicinal researchmembrane proteinsexperimental pharmacologybiochemistrypharmacologymembrane biologysignal transductioncellular physiologycellular biochemistry

Comparative Molecular, Innate, and Adaptive Impacts of Chemically Diverse Sting Agonists. Vaccine (2025)

receptorsreceptor (biochemistry)comparative molecularpharmacological researchchemical biologymedicinal chemistrymechanisms of actiondiverse sting agonistsbiological chemistrybiochemistrypharmacologyinsect sting allergyadaptive impactstoxins

In Silico Discovery and Mechanistic Profiling of Sting Agonists Engaging the Transmembrane Domain. European Journal of Medicinal Chemistry (2025)

biochemical sciencessilico discoverybiomolecular engineeringbiochemical interactiontransmembrane domainproteinlipid interactionmembrane proteinsbiological chemistrybiochemistrymembrane biologysting agonistsdrug discovery

4-Substituted-2-Thiazole Amides as Viral Replication Inhibitors of Alphaviruses. Journal of Medicinal Chemistry (2024)

Atefeh GarzanS. Kaleem AhmedNicole N. HaeseGauthami SulgeySamuel MedicaJessica L. SmithSixue ZhangFahim AhmadShuklendu KaryakarteLynn RasmussenVictor DeFilippisBabu TekwaniRobert BostwickMark J. SutoAlec J. HirschThomas E. MorrisonMark T. HeiseCorinne E. Augelli-SzafranDaniel N. StreblowAshish K. PathakOmar Moukha-Chafiq

antiviral researchmedicinal chemistryviral replication inhibitorspharmacologyviral replicationmedicinal research

Bystander Monocytic Cells Drive Infection-Independent Nlrp3 Inflammasome Response to Sars-Cov-2. mBio (2024)

Leon L. HsiehMonika LooneyAlexis FigueroaGuido MassaccesiGeorgia StavrakisEduardo U. AnayaFranco R. D'AlessioAlvaro A. OrdonezAndrew S. PekoszVictor R. DeFilippisPetros C. KarakousisAndrew H. KarabaAndrea L. Cox

microbiologyvirologyimmune responsescovid-19infectious diseasessars-cov-2immunologyimmunity (medicine)virus research

Mayaro Virus Pathogenesis and Immunity in Rhesus Macaques. PLoS neglected tropical diseases (2023)

virologymayaro virus pathogenesisinfectious diseasesvirus transmissionmedical virologyvirus-host interactionsinfectious diseases (medical specialty)immunologyviral pathogenesispathogenesisvirus research

Aging Alters Antiviral Signaling Pathways Resulting in Functional Impairment in Innate Immunity in Response to Pattern Recognition Receptor Agonists. GeroScience (2022)

Jennifer ConnorsBhavani TaramangalamGina CusimanoMatthew R. BellStephanie M. MattKaitlyn RunnerPeter J. GaskillVictor DeFilippisJanko Nikolich-ŽugichMichele A. KutzlerElias K. Haddad

functional impairmentinnate immunityvirus-host interactionsageingimmunologypharmacologyhealth sciences

Development of a Next-Generation Chikungunya Virus Vaccine Based on the Hydrovax Platform. PLoS Pathogens (2022)

Dawn K. SlifkaHans-Peter RauéWhitney C. WeberTakeshi F. AndohCraig N. KreklywichVictor R. DeFilippisDaniel N. StreblowMark K. SlifkaIan J. Amanna

vaccinationvaccinesvaccine developmentinfectious diseasesarbovirushydrovax platformvaccine designvirus research

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Victor R. DeFilippis

Oregon Health & Science University

Affiliations

Biostatistics Shared Resources

Institute Of Knight Cancer

OHSU School of Medicine

Cancer Early Detection Advanced Research Center (Cedar)

Department Of Cell, Developmental And Cancer Biology

Division Of Oncological Sciences

Center For Experimental Therapeutics

Center Of Cancer Early Detection Advanced Research (Cedar)

Institute Of Knight Cancer

Center Of Knight Cancer

Department of Medicine

Division Of Hematology/Medical Oncology

Division Of Pathobiology And Immunology

Flow Cytometry Shared Resource

Institute Of Knight Cancer

Cancer Early Detection Advanced Research Center (Cedar)

Institute Of Knight Cancer

Division Of Oncological Sciences

Institute Of Knight Cancer

Department Of Cell, Developmental And Cancer Biology

Institute Of Knight Cancer

Division Of Hematology/Medical Oncology

Institute Of Knight Cancer Insitute

Institute Of University Knight Cancer

OHSU Knight Cancer Institute

Oregon Health & Science University

NoneVictor R. Defilippis is currently serving as a Biostatistics Shared Resources faculty at Oregon Health & Science University.

Honors

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Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Victor R. DeFilippis

Oregon Health & Science University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Characterization of a Transmembrane-Activating Sting Agonist Using Genetically Humanized Mice. Cell Reports (2026)

receptorsreceptor (biochemistry)cell physiologycell biologycell signalingexperimental pharmacologymembrane biologysignal transductioncellular physiologycellular biochemistry

A Zika Virus-Like Particle Vaccine Mitigates Early Pregnancy Loss in Rhesus Macaques. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Characterization of a Novel Transmembrane Activating Sting Agonist Using Genetically Humanized Mice. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Comparative Molecular, Innate, and Adaptive Impacts of Chemically Diverse Sting Agonists. Vaccine (2025)

In Silico Discovery and Mechanistic Profiling of Sting Agonists Engaging the Transmembrane Domain. European Journal of Medicinal Chemistry (2025)

4-Substituted-2-Thiazole Amides as Viral Replication Inhibitors of Alphaviruses. Journal of Medicinal Chemistry (2024)

antiviral researchmedicinal chemistryviral replication inhibitorspharmacologyviral replicationmedicinal research

Bystander Monocytic Cells Drive Infection-Independent Nlrp3 Inflammasome Response to Sars-Cov-2. mBio (2024)

microbiologyvirologyimmune responsescovid-19infectious diseasessars-cov-2immunologyimmunity (medicine)virus research

Mayaro Virus Pathogenesis and Immunity in Rhesus Macaques. PLoS neglected tropical diseases (2023)

Aging Alters Antiviral Signaling Pathways Resulting in Functional Impairment in Innate Immunity in Response to Pattern Recognition Receptor Agonists. GeroScience (2022)

Jennifer ConnorsBhavani TaramangalamGina CusimanoMatthew R. BellStephanie M. MattKaitlyn RunnerPeter J. GaskillVictor DeFilippisJanko Nikolich-ŽugichMichele A. KutzlerElias K. Haddad

functional impairmentinnate immunityvirus-host interactionsageingimmunologypharmacologyhealth sciences

Development of a Next-Generation Chikungunya Virus Vaccine Based on the Hydrovax Platform. PLoS Pathogens (2022)

Dawn K. SlifkaHans-Peter RauéWhitney C. WeberTakeshi F. AndohCraig N. KreklywichVictor R. DeFilippisDaniel N. StreblowMark K. SlifkaIan J. Amanna

vaccinationvaccinesvaccine developmentinfectious diseasesarbovirushydrovax platformvaccine designvirus research

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10 / page