Faculty

Institution

Unit

Venue

George R. Uhl

University of Maryland, Baltimore

Affiliations

Graduate Program in Life Sciences

School of Medicine

NoneGeorge R. Uhl is currently serving as a Graduate Program In Life Sciences faculty at University of Maryland, Baltimore.

Honors

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Experiences

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Education

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George R. Uhl

University of Maryland, Baltimore

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neuroscience pharmacology neuropharmacology genetics neurology neuropsychopharmacology molecular neuroscience addiction dopamine addiction biology medicinal research neurophysiology receptors neurochemistry mammalian biology central nervous system neurogenetics neurotransmission molecular neurobiology genomics psychopharmacology biological psychiatry pharmacological research addictive behaviors molecular psychiatry pharmacotherapy neurotransmitters substance use brain science addiction medicine protein science molecular neurodegeneration opioid use disorder tobacco control genome-wide association studies pharmacokinetics vascular biology medical genetics clinical pharmacology substance addiction receptor (biochemistry) knockout mice clinical neuroscience genome biology brain function psychiatric genetics experimental pharmacology inhibitory activity addiction treatment dopamine transporter rat brain pharmacogenomics neuropsychiatry genetic disorders cellular neurobiology nicotine smoking related lung disease neural science behavioural pharmacology neuropeptide receptors neurological function brain structure m-opioid receptors behavioral effects situ hybridization dopamine transporters methamphetamine-induced hyperlocomotion extracellular dopamine vasopressin mrna m-opioid receptor dopamine transporter mutants addiction vulnerability cessation success drug addiction immunohistochemical localization functional expression medicine neurodegenerative disorders parkinson's disease complex genetics restless leg syndrome

Notable Scholarly Works

Notable Federal Grants

Collaborators

Sex Differences in the Reduction of Hopelessness in Μ Opioid Receptor Deficient Mice by Additive Effects of Δ Opioid Receptor Agonists. The International Journal of Neuropsychopharmacology (2025)

*Yuki MoriyaYoshiyuki KasaharaMasafumi ShimadaYasufumi SakakibaraHideaki FujiiHiroshi NagaseSoichiro IdeKazutaka IkedaFrank Scott HallGeorge R UhlIchiro Sora

opioid use disorderneuropsychopharmacologyadditive effectsneuropharmacologyopioid overdosebehavioral sciences

Opioid Receptor Antagonists Reduce Motivated Wheel-Running Behavior in Mice. Behavioural Pharmacology (2024)

Nobue KitanakaKanayo AraiKaoko TakeharaF. Scott HallKazuo TomitaKento IgarashiTomoaki SatoGeorge R. UhlJunichi Kitanaka

animal behaviorpharmacologyopioid receptor antagonistsexperimental psychologymotor behaviorwheel-running behaviorneurosciencebehavioral sciences

Protein Phosphatase 2A Inhibitors: A Possible Pharmacotherapy for Benzodiazepine Dependence. Journal of Pharmacy and Pharmacology (2024)

Chisa KobayashiNobue KitanakaMasanori NakaiF Scott HallKazuo TomitaKento IgarashiTomoaki SatoGeorge R UhlJunichi Kitanaka

medicinal chemistrydrug metabolismmolecular pharmacologyapplied pharmacologyclinical pharmacologymedicinepharmacokineticspossible pharmacotherapybenzodiazepine dependencetranslational pharmacologyprotein phosphorylationtherapeutic targetspharmacological researchenzyme inhibitionpharmacologypharmacotherapydrug discoverymolecular biologymedicinal researchtreatment options

Glycogen Synthase Kinase-3 Inhibitors Block Morphine-Induced Locomotor Activation, Straub Tail, and Depression of Rearing in Mice via a Possible Central Action. Neurochemical Research (2023)

Junichi KitanakaNobue KitanakaKazuo TomitaF. Scott HallKento IgarashiGeorge R. UhlTomoaki Sato

drug treatmentmorphine-induced locomotor activationneurologyreceptor tyrosine kinasesneuropharmacologycentral nervous systemneuropsychopharmacologymammalian biologydrug targetingpharmacological researchenzyme inhibitionpharmacologystraub tailanesthetic pharmacologyneurochemistrydepressionpharmacotherapydrug discoveryneuroscienceneurophysiology

Heterozygous and Homozygous Gene Knockout of the 5-Ht1B Receptor Have Different Effects on Methamphetamine-Induced Behavioral Sensitization. Behavioural Pharmacology (2023)

Yuki MoriyaYoshiyuki KasaharaKana IshiharaFrank Scott HallYoko HaginoRené HenKazutaka IkedaGeorge R. UhlIchiro Sora

biological psychiatrybehavioural pharmacologyreceptorsneuropsychopharmacologypharmacologypsychopharmacologyhomozygous gene knockoutgeneticsdepressionneuropharmacologypharmacotherapygene functionaddictiondrug discoverymethamphetamine-induced behavioral sensitizationaddictive behaviorsbehavioral sciences

Role of Glycogen Synthase Kinase-3β in Dependence and Abuse Liability of Alcohol. Alcohol and Alcoholism (2023)

Masahiro OkaRui YoshinoNobue KitanakaF Scott HallGeorge R UhlJunichi Kitanaka

substance abusealcohol (drug)pharmacologyalcohol misusepsychiatryaddictiontoxicologyalcohol abuseabuse liabilityharm reductionhealth sciencesalcohol dependence

Selecting the Appropriate Hurdles and Endpoints for Pentilludin, a Novel Antiaddiction Pharmacotherapeutic Targeting the Receptor Type Protein Tyrosine Phosphatase D. Frontiers in Psychiatry (2023)

George R. Uhl

novel antiaddictionpsychiatric disorderstherapeutic targetspsychiatric researchpsychiatry

Are Histamine H3 Antagonists the Definitive Treatment for Acute Methamphetamine Intoxication?. Current Drug Research Reviews (2022)

Nobue KitanakaJunichi Kitanaka,F. Scott HallKoh-ichi Tanaka,Kazuo TomitaKento IgarashiNobuyoshi NishiyamaTomoaki SatoGeorge R. Uhl

immunologymedicinal chemistrymedicinepharmacologydrug treatmentpain medicineclinical evidencepharmacotherapytherapeutic targetsneuropharmacologydrug resistanceclinical researchrespiratory medicinemedicinal researchacute methamphetamine intoxicationdefinitive treatment

Glycogen Synthase Kinase-3 Inhibitors Suppress Morphine-Induced Straub’s Tail via a Centrally Acting Mechanism. Research Square (Research Square) (2022)

Junichi KitanakaNobue KitanakaKazuo TomitaF. Scott HallKento IgarashiGeorge R. UhlTomoaki Sato

medicinal chemistryneurologyenzyme inhibitionpharmacologypharmacokineticsanesthetic pharmacologypharmacotherapyneuropharmacologymolecular pharmacologydrug discoveryclinical researchaddiction biologymedicinal researchneuroscience

Role for μ-Opioid Receptor in Antidepressant Effects of δ-Opioid Receptor Agonist Knt-127. Journal of Pharmacological Sciences (2022)

Yuki MoriyaYoshiyuki KasaharaMasafumi ShimadaYasufumi SakakibaraHideaki FujiiHiroshi NagaseSoichiro IdeKazutaka IkedaF. Scott HallGeorge R. UhlIchiro Sora

pharmacologypharmacotherapyneuropharmacologym-opioid receptorantidepressant effectsclinical pharmacology

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George R. Uhl

University of Maryland, Baltimore

Affiliations

Graduate Program in Life Sciences

School of Medicine

NoneGeorge R. Uhl is currently serving as a Graduate Program In Life Sciences faculty at University of Maryland, Baltimore.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

George R. Uhl

University of Maryland, Baltimore

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Sex Differences in the Reduction of Hopelessness in Μ Opioid Receptor Deficient Mice by Additive Effects of Δ Opioid Receptor Agonists. The International Journal of Neuropsychopharmacology (2025)

*Yuki MoriyaYoshiyuki KasaharaMasafumi ShimadaYasufumi SakakibaraHideaki FujiiHiroshi NagaseSoichiro IdeKazutaka IkedaFrank Scott HallGeorge R UhlIchiro Sora

opioid use disorderneuropsychopharmacologyadditive effectsneuropharmacologyopioid overdosebehavioral sciences

Opioid Receptor Antagonists Reduce Motivated Wheel-Running Behavior in Mice. Behavioural Pharmacology (2024)

Nobue KitanakaKanayo AraiKaoko TakeharaF. Scott HallKazuo TomitaKento IgarashiTomoaki SatoGeorge R. UhlJunichi Kitanaka

animal behaviorpharmacologyopioid receptor antagonistsexperimental psychologymotor behaviorwheel-running behaviorneurosciencebehavioral sciences

Protein Phosphatase 2A Inhibitors: A Possible Pharmacotherapy for Benzodiazepine Dependence. Journal of Pharmacy and Pharmacology (2024)

Chisa KobayashiNobue KitanakaMasanori NakaiF Scott HallKazuo TomitaKento IgarashiTomoaki SatoGeorge R UhlJunichi Kitanaka

Glycogen Synthase Kinase-3 Inhibitors Block Morphine-Induced Locomotor Activation, Straub Tail, and Depression of Rearing in Mice via a Possible Central Action. Neurochemical Research (2023)

Junichi KitanakaNobue KitanakaKazuo TomitaF. Scott HallKento IgarashiGeorge R. UhlTomoaki Sato

Heterozygous and Homozygous Gene Knockout of the 5-Ht1B Receptor Have Different Effects on Methamphetamine-Induced Behavioral Sensitization. Behavioural Pharmacology (2023)

Yuki MoriyaYoshiyuki KasaharaKana IshiharaFrank Scott HallYoko HaginoRené HenKazutaka IkedaGeorge R. UhlIchiro Sora

Role of Glycogen Synthase Kinase-3β in Dependence and Abuse Liability of Alcohol. Alcohol and Alcoholism (2023)

Masahiro OkaRui YoshinoNobue KitanakaF Scott HallGeorge R UhlJunichi Kitanaka

substance abusealcohol (drug)pharmacologyalcohol misusepsychiatryaddictiontoxicologyalcohol abuseabuse liabilityharm reductionhealth sciencesalcohol dependence

Selecting the Appropriate Hurdles and Endpoints for Pentilludin, a Novel Antiaddiction Pharmacotherapeutic Targeting the Receptor Type Protein Tyrosine Phosphatase D. Frontiers in Psychiatry (2023)

George R. Uhl

novel antiaddictionpsychiatric disorderstherapeutic targetspsychiatric researchpsychiatry

Are Histamine H3 Antagonists the Definitive Treatment for Acute Methamphetamine Intoxication?. Current Drug Research Reviews (2022)

Nobue KitanakaJunichi Kitanaka,F. Scott HallKoh-ichi Tanaka,Kazuo TomitaKento IgarashiNobuyoshi NishiyamaTomoaki SatoGeorge R. Uhl

Glycogen Synthase Kinase-3 Inhibitors Suppress Morphine-Induced Straub’s Tail via a Centrally Acting Mechanism. Research Square (Research Square) (2022)

Junichi KitanakaNobue KitanakaKazuo TomitaF. Scott HallKento IgarashiGeorge R. UhlTomoaki Sato

Role for μ-Opioid Receptor in Antidepressant Effects of δ-Opioid Receptor Agonist Knt-127. Journal of Pharmacological Sciences (2022)

Yuki MoriyaYoshiyuki KasaharaMasafumi ShimadaYasufumi SakakibaraHideaki FujiiHiroshi NagaseSoichiro IdeKazutaka IkedaF. Scott HallGeorge R. UhlIchiro Sora

pharmacologypharmacotherapyneuropharmacologym-opioid receptorantidepressant effectsclinical pharmacology

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10 / page

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Johns Hopkins University

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substance abuse

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