Trimmer, Elizabeth

Grinnell College

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Grinnell College

NoneTrimmer, Elizabeth is currently serving as a Grinnell College faculty at Grinnell College.

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Trimmer, Elizabeth

Grinnell College

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biochemistry molecular biology enzymes protein science methylenetetrahydrofolate reductase biosynthesis structural biology redox biology structural molecular biology enzyme catalysis structure-function enzyme kinetics microbiology molecular metabolism redox signaling biophysics chemical biology free radical biology biocatalysis enzymatic modification protein synthesis bacteria biophysical chemistry catalysis bioorganic chemistry biological macromolecules transition metal chemistry peptide science enzyme inhibition bacteriology bioelectrochemistry surface reactivity cellular enzymology conformational studies protein chemistry functional modification kinetic mechanism rapid-reaction studies folate activation escherichia coli folate oxidative half-reaction folate half-reaction functional role kinetic characterization mutant methylenetetrahydrofolate reductase

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 2613 Exploring a Proton Relay Mechanism Involving Glu28, His273, and Ser26 in the Folate Half-Reaction of E. Coli Methylenetetrahydrofolate Reductase (Mthfr). Journal of Biological Chemistry (2025)

Abstract 2011: A Role for Serine 26 in the Folate Half Reaction of E. Coli Methylenetetrahydrofolate Reductase (Mthfr). Journal of Biological Chemistry (2023)

Abstract 2062: Importance of Leucine 277 for Nadh Binding in Methylenetetrahydrofolate Reductase. Journal of Biological Chemistry (2023)

A Proposed Proton Relay Mechanism in Methylenetetrahydrofolate Reductase. The FASEB Journal (2020)

Kinetic Characterization of Escherichia Coli Mutant Methylenetetrahydrofolate Reductase Flavoenzymes Leu277Ala and Leu277ile. The FASEB Journal (2020)

Kinetic Characterization of Mutant Methylenetetrahydrofolate Reductase Enzymes His273Ala and His273gln. The FASEB Journal (2020)

Siyuan DuMaxwell G. TetrickRichard LiJason ChienElizabeth E. Trimmer

enzymeskinetic characterizationprotein sciencebiochemistrymolecular biologymutant methylenetetrahydrofolate reductasegenetics

A Role for Glutamine 183 in the Folate Oxidative Half-Reaction of Methylenetetrahydrofolate Reductase From Escherichia Coli. Archives of Biochemistry and Biophysics (2018)

Chong ZuoAmber L. JollyAndriana P. NikolovaDavid I. SatzerSirui CaoJeremy S. SanchezDavid P. BallouElizabeth E. Trimmer

redox signalingstructural molecular biologybiosynthesismethylenetetrahydrofolate reductaseenzymesprotein synthesismolecular biologyoxidative stressescherichia colibiochemistrystructural biologybiophysicsenzymatic modificationmetabolismfolate oxidative half-reactionmolecular metabolismprotein scienceenzyme catalysisstructure-function enzyme kineticsfree radical biologyredox biology

Mechanistic Studies of an Amine Oxidase Derived From D -Amino Acid Oxidase. Biochemistry (2017)

Construction of Escherichia Coli Plasmid Vectors Encoding Site‐Specific Methylenetetrahydrofolate Reductase Mutants (769.12). The FASEB Journal (2014)

The Minor Role of Gln 183 in the Nadh Reductive Half‐Reaction of E. Coli Methylenetetrahydrofolate Reductase (769.10). The FASEB Journal (2014)