Faculty

Institution

Unit

Venue

Timothy Hoffman

Professor

University of Missouri

Affiliations

School of Medicine

Department of Medicine

Timothy Hoffman is currently serving as a Medicine Professor at University of Missouri.

Honors

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Experiences

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Education

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Timothy Hoffman

University of Missouri

Professor

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radiation oncology oncology pharmacology nuclear medicine cancer research medicine tumor targeting cancer imaging medical imaging prostate cancer radiology cancer treatment medicinal research drug discovery peptides cancer biology radiation anti-cancer agents biomedical imaging receptors drug targeting medicinal chemistry nuclear science coordination chemistry cancer care radiation therapy pharmacotherapy peptide science cellular therapy radiation biology radiopharmaceutical therapy transition metal chemistry colorectal cancer protein science enzyme inhibition bioconjugation molecular cancer animal science biomarker target radiation chemistry biological evaluation melanoma peptide engineering endocrine oncology gastrointestinal oncology inorganic synthesis pharmaceutical sciences radiation application clinical radiation oncology oncologic imaging cancer genomics vivo evaluation radiochemical investigations synthetic chemistry nuclear engineering computed tomography peptide synthesis specific targeting peptide receptor positron emission tomography neurochemistry hepatocellular carcinoma drug development pharmaceutical chemistry breast oncology positron-emission tomography imaging peptide conjugates gastrin-releasing peptide receptors melanoma therapy receptor-avid peptide conjugates pet imaging human colon cancers guanylin receptors therapeutic radiopharmaceuticals bombesin receptor novel series

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 3392: Generation and Characterization of Transgenic Oncopig Model for Lung Cancer. Cancer Research (2024)

Kirtan JoshiNagabhishek SirpuAmanda SchmelzleRavikanth PoonooruBenjamin NelsonPradeep SubramanyamColleen GarrettMariana SponchiadoSarah SchlinkSamantha GerbJesse PorterDae KimJeffrey KuninJeffrey BryanTimothy HoffmanBhanu TeluguJussuf KaifiSatyanarayana Rachagani

dermatologygenitourinary cancersthoracic oncologytransgenic oncopig modelgeneticstumor biologylung cancercancer researchcancer treatmentradiation oncologymedicinal researchrespiratory medicinecellular therapycancer carecancer biologyclinical researchcancer geneticscancer genomicsoncology

Benefits and Opportunities of the Transgenic Oncopig Cancer Model. Trends in cancer (2024)

Kirtan JoshiBhanu P. TeluguRandall S. PratherJeffrey N. BryanTimothy J. HoffmanJussuf T. KaifiSatyanarayana Rachagani

oncologymedicinegenetics

Characterization of a Bronchoscopically Induced Transgenic Lung Cancer Pig Model for Human Translatability. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Kirtan JoshiKanve N. SuvileshNagabhishek Sirpu NateshYariswamy ManjunathJared CoberlySarah SchlinkJeffrey R. KuninRandall S. PratherKristin WhitworthBenjamin NelsonJeffrey N. BryanTimothy HoffmanMojgan GolzyMurugesan RajuEmma TeixeiroBhanu P. TeluguJussuf T. KaifiSatyanarayana Rachagani

biomedical engineeringhuman translatabilitylung cancer

PIGS: Large Animal Preclinical Cancer Models. World Journal of Oncology (2024)

Kirtan JoshiTejas KatamAkshata HegdeJianlin ChengRandall S. PratherKristin WhitworthKevin WellsJeffrey N. BryanTimothy HoffmanBhanu P. TeluguJussuf T. KaifiSatyanarayana Rachagani

global healthanimal scienceoncology

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

biophysicscrystal structurescrystal researchdeposited datasetstructural chemistryccdc 2157502crystal engineeringcrystallographystructure determinationstructure elucidationchemistrychemical structurecrystal diffraction study

Synthesis and Preclinical Evaluation of a Novel Fluorine-18 Labeled Small-Molecule Pet Radiotracer for Imaging of Cxcr3 Receptor in Mouse Models of Atherosclerosis. EJNMMI Research (2023)

Santosh R. AlluriYusuke HigashiAshley BerendzenLaurel A. GrisantiLisa D. WatkinsonKamlendra SinghTimothy J. HoffmanTerry CarmackElizabeth A. DevannyMiles TannerKun-Eek Kil

tissue imagingpharmacologybiomedical imagingvascular biologytumor biologycell biologyatherosclerosisradiologymouse modelspreclinical evaluationnovel imaging methodsreceptorsmedical imagingmedicinal researchmolecular imagingmolecular basistherapeutic imagingprotein sciencesmall-molecule pet radiotracercancer imagingmolecular evidence

Low-Intensity Blast Induces Acute Glutamatergic Hyperexcitability in Mouse Hippocampus Leading to Long-Term Learning Deficits and Altered Expression of Proteins Involved in Synaptic Plasticity and Serine Protease Inhibitors. Neurobiology of Disease (2022)

Shanyan ChenHeather R. SiedhoffHua ZhangPei LiuAshley BalderramaRunting LiCatherine JohnsonC. Michael GreenliefBastijn KoopmansTimothy HoffmanRalph G. DePalmaDe-Pei LiJiankun CuiZezong Gu

neural scienceneuroanatomymolecular neurobiologyneurosciencelong-term learning deficitsneurophysiologygeneticsneuroinflammationserine protease inhibitorsclinical neurosciencemolecular neuroscienceglutamatergic hyperexcitabilitysynaptic plasticitybrain functionneurologymouse hippocampuscognitive neurosciencebrain injurymammalian biology

A New, Second Generation Trithiol Bifunctional Chelate for 72,77 as: Trithiol(B)-(Ser) 2 -Rm2. Bioconjugate Chemistry (2021)

Firouzeh Najafi KhosroshahiYutian FengLi MaSimon ManringTammy L. RoldFabio A. GallazziSteven P. KelleyMary F. EmbreeHeather M. HennkensTimothy J. HoffmanSilvia S. Jurisson

bioconjugationchemical synthesisorganic synthesisbiochemistry

Abstract 5344: Treatment Efficacy of 212Pb-Rm2 Targeted Alpha Therapy in Human Prostate Cancer Cell Lines: An in Vitro Investigation. Cancer Research (2020)

Tammy L. RoldNkemakonam C. OkoyeThomas P. QuinnTimothy J. Hoffman

radiation oncologycancer cellstumor targetingtreatment efficacydrug targetingmedicinal researchprostate cancercellular therapycancer researchpharmacologytherapeutic targetstherapeutic efficacyclinical researchurologycancer treatmentcancer careoncologycancer biology

Abstract 5346: Preclinical Evaluation of Maximum Tolerated Dose (Mtd) Following Single Dose Administration of 212Pb-Rm2. Cancer Research (2020)

Tammy L. RoldElisabeth A. DevannyNkemakonam C. OkoyeThomas P. QuinnTimothy J. Hoffman

radiation oncologysingle dose administrationcancer researchpreclinical evaluationmedicinecancer careoncologycancer biology

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Timothy Hoffman

Professor

University of Missouri

Affiliations

School of Medicine

Department of Medicine

Timothy Hoffman is currently serving as a Medicine Professor at University of Missouri.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Timothy Hoffman

University of Missouri

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 3392: Generation and Characterization of Transgenic Oncopig Model for Lung Cancer. Cancer Research (2024)

Benefits and Opportunities of the Transgenic Oncopig Cancer Model. Trends in cancer (2024)

Kirtan JoshiBhanu P. TeluguRandall S. PratherJeffrey N. BryanTimothy J. HoffmanJussuf T. KaifiSatyanarayana Rachagani

oncologymedicinegenetics

Characterization of a Bronchoscopically Induced Transgenic Lung Cancer Pig Model for Human Translatability. bioRxiv (Cold Spring Harbor Laboratory) (2024)

biomedical engineeringhuman translatabilitylung cancer

PIGS: Large Animal Preclinical Cancer Models. World Journal of Oncology (2024)

Kirtan JoshiTejas KatamAkshata HegdeJianlin ChengRandall S. PratherKristin WhitworthKevin WellsJeffrey N. BryanTimothy HoffmanBhanu P. TeluguJussuf T. KaifiSatyanarayana Rachagani

global healthanimal scienceoncology

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

Synthesis and Preclinical Evaluation of a Novel Fluorine-18 Labeled Small-Molecule Pet Radiotracer for Imaging of Cxcr3 Receptor in Mouse Models of Atherosclerosis. EJNMMI Research (2023)

Santosh R. AlluriYusuke HigashiAshley BerendzenLaurel A. GrisantiLisa D. WatkinsonKamlendra SinghTimothy J. HoffmanTerry CarmackElizabeth A. DevannyMiles TannerKun-Eek Kil

Shanyan ChenHeather R. SiedhoffHua ZhangPei LiuAshley BalderramaRunting LiCatherine JohnsonC. Michael GreenliefBastijn KoopmansTimothy HoffmanRalph G. DePalmaDe-Pei LiJiankun CuiZezong Gu

A New, Second Generation Trithiol Bifunctional Chelate for 72,77 as: Trithiol(B)-(Ser) 2 -Rm2. Bioconjugate Chemistry (2021)

Firouzeh Najafi KhosroshahiYutian FengLi MaSimon ManringTammy L. RoldFabio A. GallazziSteven P. KelleyMary F. EmbreeHeather M. HennkensTimothy J. HoffmanSilvia S. Jurisson

bioconjugationchemical synthesisorganic synthesisbiochemistry

Abstract 5344: Treatment Efficacy of 212Pb-Rm2 Targeted Alpha Therapy in Human Prostate Cancer Cell Lines: An in Vitro Investigation. Cancer Research (2020)

Tammy L. RoldNkemakonam C. OkoyeThomas P. QuinnTimothy J. Hoffman

Abstract 5346: Preclinical Evaluation of Maximum Tolerated Dose (Mtd) Following Single Dose Administration of 212Pb-Rm2. Cancer Research (2020)

Tammy L. RoldElisabeth A. DevannyNkemakonam C. OkoyeThomas P. QuinnTimothy J. Hoffman

radiation oncologysingle dose administrationcancer researchpreclinical evaluationmedicinecancer careoncologycancer biology

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5
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10 / page

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cancer imaging

oncology

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