Faculty

Institution

Unit

Venue

Thomas Malek

Professor and Chairman of Microbiology and Immunology

University of Miami

Affiliations

Miller School of Medicine

Microbiology and Immunology

Thomas Malek is currently serving as a Microbiology And Immunology Professor and Chairman of Microbiology and Immunology at University of Miami.

Honors

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Experiences

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Education

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Thomas Malek

University of Miami

Professor and Chairman of Microbiology and Immunology

You can click a keyword to filter the displayed items

immunology immune responses cell signaling cell biology cytokines t-regulatory cell adaptive immune system receptors pharmacology medicine cellular immune responses hematology clinical immunology cell regulation gene expression signal transduction immunotherapy molecular immunology autoimmunity medicinal research mammalian biology innate immune system experimental medicine cellular therapy lymphocyte development cell transplantation developmental immunology immunochemistry tumor targeting cell death experimental biology clinical transplantation apoptosis molecular regulation tumor suppressors cancer treatment transplantation medicine leukemia bone marrow transplantation receptor (biochemistry) immunomodulation cell therapy cancer biology oncogenes molecular cancer molecular cell biology tolerance induction insulin signaling gene regulation immunogenetics cellular regulatory mechanism antitumor immunity cytokine receptors nod mice diabetes therapies protein science signaling pathways histocompatibility monoclonal antibodies diabetes research clinical investigation knockout mice cell growth novel therapies selective expression initial characterization lymphocyte activation functional maturation thymic development peripheral homeostasis immune regulation receptor expression lethal autoimmunity granulocyte-differentiation antigen mouse bone marrow myeloid lineage cells immune dysregulation reproductive immunology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Blimp-1 and Ceacam1 Cooperatively Regulate Human Treg Homeostasis and Function to Control Xenogeneic Gvhd. JCI Insight (2025)

immunologyg protein-coupled receptorxenogeneic gvhdcellular physiologymolecular and cellular biologymolecular cell biologyhuman treg homeostasisimmune responseshomeostatic mechanismsmolecular medicinecell biology

Growth of Human Regulatory Cd4+ T Cells is More Tightly Controlled Than Effector T Cells Due to Distinctive Molecular Programming. iScience (2025)

immunologycellular immune responsescell signalingcell researchtranscription factorsmolecular cell biologyimmune responsest-regulatory celleffector t cellsmolecular programmingcell biology

The Role of Viruses in the Glioma Tumor Microenvironment: Immunosuppressors or Primers for Anti-Tumor Immunity?. Cancers (2025)

immunologyvirus researchanti-tumor immunitygliomasmedical virologybrain tumor researchcancer immunosurveillancevirologyglioma tumor microenvironmentpathologyviral oncologyimmunotherapy

Bi-Functional Il2/Cd25/Il10 Fusion Protein Promotes Tregs, Reduces Inflammation, and is Highly Effective in Limiting Diabetes in Nod Mice. The Journal of Immunology (2024)

Alicia Santos SavioSarah WelfordThomas Malek

immunologydiabetesimmunologic mechanismsreduces inflammationchronic inflammationimmune dysregulationnod miceimmune responsesimmunopathologyhost responseinflammation

Blimp-1 and Ceacam1 Cooperate to Regulate Human Regulatory T Cell Proliferation and Function. The Journal of Immunology (2024)

Ying DingAixin YuMilos VujanacSabrina CopselAlejandro MoroLuis NiveloNicolas TchitchekMichelle RosenzwajgAlejandro VillarinoRobert LevyDavid KoatzmannThomas Malek

immunologyt-regulatory cellimmune responses

Highly Efficient Il-2-Dependent Gene Activation by a Single Wave of Il-2R Signaling in Human Regulatory T Cells. The Journal of Immunology (2024)

Milos VujanacAixin YuThomas Malek

immunologyimmunologic mechanismscell signalingt-regulatory cellimmune responsessignal transduction

Interleukin-2 Receptor Signaling Acts as a Checkpoint That Influences the Distribution of Regulatory T Cell Subsets. iScience (2024)

Acacia N ShouseAlejandro V VillarinoThomas R Malek

immunologyreceptorscellular immune responsescell signalingcytokinesmolecular biologyimmune responsest-regulatory cellsignal transductioncell biology

Interleukin-2 Signaling in the Regulation of T Cell Biology in Autoimmunity and Cancer. Immunity (2024)

Acacia N. ShouseKathryn M. LaPorteThomas R. Malek

immunologycell signalingautoimmunitysignal transductioncell regulation

Low-Dose Mil-2/Cd25 Alters the Composition and Reduces the Frequency of Autoreactive T Cell Subsets in Inflamed Islets From Nod Mice. The Journal of Immunology (2024)

Janika PõderThomas Malek

immunologyimmunologic mechanismsinflamed isletsimmune responsesnod mice

Notch1 Blockade by a Novel, Selective Anti-Notch1 Neutralizing Antibody Improves Immunotherapy Efficacy in Melanoma by Promoting an Inflamed Tme. Journal of Experimental & Clinical Cancer Research (2024)

Juliano Tiburcio de FreitasVarsha ThakurKathryn M. LaPorteVijay S. ThakurBrian FloresValentina CaicedoChioma G. E. AjaegbuGiuseppe IngrasciZoe M. LipmanKeman ZhangHong QiuThomas R. MalekBarbara Bedogni

melanomanovel therapiesimmunotherapy efficacytherapeutic efficacytumor targetingcancer researchcancer immunotherapyinflamed tmecancer treatmentimmunotherapyimmunologypharmacologycancer discoverypharmacotherapybiomolecular engineeringoncologyclinical researchmedicinal researchexperimental medicine

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Thomas Malek

Professor and Chairman of Microbiology and Immunology

University of Miami

Affiliations

Miller School of Medicine

Microbiology and Immunology

Thomas Malek is currently serving as a Microbiology And Immunology Professor and Chairman of Microbiology and Immunology at University of Miami.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Thomas Malek

University of Miami

Professor and Chairman of Microbiology and Immunology

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Blimp-1 and Ceacam1 Cooperatively Regulate Human Treg Homeostasis and Function to Control Xenogeneic Gvhd. JCI Insight (2025)

Growth of Human Regulatory Cd4+ T Cells is More Tightly Controlled Than Effector T Cells Due to Distinctive Molecular Programming. iScience (2025)

immunologycellular immune responsescell signalingcell researchtranscription factorsmolecular cell biologyimmune responsest-regulatory celleffector t cellsmolecular programmingcell biology

The Role of Viruses in the Glioma Tumor Microenvironment: Immunosuppressors or Primers for Anti-Tumor Immunity?. Cancers (2025)

immunologyvirus researchanti-tumor immunitygliomasmedical virologybrain tumor researchcancer immunosurveillancevirologyglioma tumor microenvironmentpathologyviral oncologyimmunotherapy

Bi-Functional Il2/Cd25/Il10 Fusion Protein Promotes Tregs, Reduces Inflammation, and is Highly Effective in Limiting Diabetes in Nod Mice. The Journal of Immunology (2024)

Alicia Santos SavioSarah WelfordThomas Malek

immunologydiabetesimmunologic mechanismsreduces inflammationchronic inflammationimmune dysregulationnod miceimmune responsesimmunopathologyhost responseinflammation

Blimp-1 and Ceacam1 Cooperate to Regulate Human Regulatory T Cell Proliferation and Function. The Journal of Immunology (2024)

Ying DingAixin YuMilos VujanacSabrina CopselAlejandro MoroLuis NiveloNicolas TchitchekMichelle RosenzwajgAlejandro VillarinoRobert LevyDavid KoatzmannThomas Malek

immunologyt-regulatory cellimmune responses

Highly Efficient Il-2-Dependent Gene Activation by a Single Wave of Il-2R Signaling in Human Regulatory T Cells. The Journal of Immunology (2024)

Milos VujanacAixin YuThomas Malek

immunologyimmunologic mechanismscell signalingt-regulatory cellimmune responsessignal transduction

Interleukin-2 Receptor Signaling Acts as a Checkpoint That Influences the Distribution of Regulatory T Cell Subsets. iScience (2024)

Acacia N ShouseAlejandro V VillarinoThomas R Malek

immunologyreceptorscellular immune responsescell signalingcytokinesmolecular biologyimmune responsest-regulatory cellsignal transductioncell biology

Interleukin-2 Signaling in the Regulation of T Cell Biology in Autoimmunity and Cancer. Immunity (2024)

Acacia N. ShouseKathryn M. LaPorteThomas R. Malek

immunologycell signalingautoimmunitysignal transductioncell regulation

Low-Dose Mil-2/Cd25 Alters the Composition and Reduces the Frequency of Autoreactive T Cell Subsets in Inflamed Islets From Nod Mice. The Journal of Immunology (2024)

Janika PõderThomas Malek

immunologyimmunologic mechanismsinflamed isletsimmune responsesnod mice

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Similar Faculty Members

Bellur S Prabhakar

Institution

University of Illinois Chicago

cellular therapy

immune response

Ivan P. Maillard

Institution

University of Pennsylvania

developmental biology

haematopoiesis

Glen N. Barber, Ph.D

Institution

University of Miami

microbial infection

immunology

Harvey Cantor

Institution

Harvard University

t-regulatory cell

pathology

Randolph J. Noelle

Institution

Dartmouth College

cellular therapy

immune response

Kai Wucherpfennig

Institution

Harvard University

immunology

immune responses

Jenny Ting

Institution

University of North Carolina at Chapel Hill

gene discovery

innate immune system

Edgar Engleman

Institution

Stanford University

cellular therapy

immune response

Jianzhu Chen

Institution

Massachusetts Institute of Technology

human diseases

nanoparticle research

David Rawlings

Institution

University of Washington

clinical immunology

transplant infectious disease