Faculty

Institution

Unit

Venue

Thomas Huckaba

Xavier University of Louisiana

Affiliations

Department Of Institutional Advancement

Department Of Mass Communication

Department Of Pharmacy Practice

Xavier University of Louisiana

NoneThomas Huckaba is currently serving as a Institutional Advancement faculty at Xavier University of Louisiana.

Honors

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Experiences

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Education

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Thomas Huckaba

Xavier University of Louisiana

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cell biology developmental biology pharmacology genetics structural biology cytoskeleton yeast membrane biology mammalian biology gene expression diabetes diabetes therapies ophthalmology retina diabetes research movement disorders retina protein function live cell imaging botany gene therapy translational research complementary medicine pharmacotherapy oncogenes medicinal research cellular therapy musculoskeletal disorders diabetic medicine experimental medicine experimental gerontology bioenergetics nature fungal developmental biology novel therapies therapeutic efficacy clinical therapeutics systemic therapy individual therapy experimental biology disease gene identification mendelian disorder degenerative disease genetic disorders eye health ocular pathology experimental ophthalmology ocular disease in vivo systems biological function nutrient physiology mitochondrial function microvascular dysfunction diabetes mellitus biomedical research off-target effects cellular structure oocytes oogenesis molecular research enzyme specificity enzymatic modification budding yeast cable-dependent movement actin patches mitochondrial movement actin cables type ii myosin retrograde actin flow cross-bridging mechanism clinical therapy actin comet tails kinesin switch streptozotocin-induced diabetic mice protective effects actin cytoskeleton nutrient metabolism

Notable Scholarly Works

Notable Federal Grants

Collaborators

Discovery of Hiv-1 Integrase Protac Degraders With Potent Activity Against Viral Infection. SSRN Electronic Journal (2026)

hivantiviral researchpharmacologyfuture medicinal chemistryantiviral drugsbiomolecular engineeringvirologydrug discoveryhuman retrovirusviral infectionpotent activityantiviral drug developmentbiochemistry

Abstract 2110 Catalytic Function of Lysine Deacetylase 6 is Critical for Cell Motility and Cell Division. Journal of Biological Chemistry (2025)

enzyme inhibitioncatalytic functionenzyme specificitycell divisionchemical biologyenzymesmolecular metabolismbiological chemistryenzymatic modificationenzyme catalysisabstract 2110cellular enzymologycellular biochemistrybiochemistrycell biology

Lysine Deacetylases (Kdacs or Hdacs) Biological Effects Assessed by Flow Cytometry in Ht1080 Cells. Open MIND (2025)

flow cytometrybioanalysishematologylysine deacetylasesclinical biochemistrymetabolismht1080 cellsbiochemistrycell biology

Discovery of Oral Degraders of the Ros1 Fusion Protein With Potent Activity Against Secondary Resistance Mutations. Journal of Medicinal Chemistry (2024)

molecular researchoral degradersprotein functionmolecular cell biologymolecular biologydna repairros1 fusion proteinprotein sciencemutagenesis (molecular biology technique)secondary resistance mutationsbiochemistry

Lysine Deacetylase Inhibitors Have Low Selectivity in Cells and Exhibit Predominantly Off‐Target Effects. FEBS Open Bio (2024)

Kiara E. BornesMarcus A. MoodyThomas M. HuckabaMegan C. BenzEmily C. McConnellMaryam ForoozeshVan H. BarnesBridgette M. Collins‐BurowMatthew E. BurowTerry J. WattTasha B. Toro

low selectivityenzyme inhibitionpharmacologybiomedical researchbiomolecular engineeringdrug discoveryoff-target effectslysine deacetylase inhibitorsbiochemistry

Lysine Deacetylases (Kdacs or Hdacs) Biological Effects Assessed by Fixed Cell Fluorescence Microscopy in Ht1080 Cells. Open MIND (2024)

lysine deacetylasescell fluorescence microscopycell researchfluorescencemolecular biologybiomedical analysisbiological imagingbiological chemistryht1080 cellsbiochemical sciencescellular biochemistrybiochemistrymolecular imaging

Study of Ceramide-Flavone Analogs Showing Selffluorescence and Anti-Proliferation Activities. Journal of Oncology Research and Therapy (2023)

Navneet GoyalCamilla DoMiriam Hill-OdomTeresa BeamonTulasi PonnapakkamJiawang LiuJayalakshmi SridharThomas HuckabaMaryam Foroozesh

pharmacologycancer researchoncologyceramide-flavone analogscancer treatmentanti-proliferation activities

Identification of a Modulator of the Actin Cytoskeleton, Mitochondria, Nutrient Metabolism and Lifespan in Yeast. Nature Communications (2022)

Cierra N. SingEnrique J. GarciaThomas G. LipkinThomas M. HuckabaCatherine A. TsangArielle C. CoughlinEmily J. YangIstvan R. BoldoghRyo Higuchi-SanabriaLiza A. Pon

experimental gerontologylongevityin vivo systemsbioenergeticsnatureyeastbiological functionstructural biologymembrane biologymammalian biologydevelopmental biologybiomechanicsactin cytoskeletongene expressionnutrient physiologynutrient metabolismmitochondrial functiongeneticsneuroscience

Tube‐Like Structures Within the Ovarian Follicle of Hydrolagus Colliei Indicate the Early Origins of Follicle Cell Processes. Journal of Fish Biology (2020)

Lydia CrawfordHenry BartEnrique L. HaroldThomas M. HuckabaIan R. Davenport

fish biologyavian biologytube-like structuresbiologymammalian biologyreproductive biologyovarian follicledevelopmental biologystructural biologyfollicle cell processesgynecology

Computational and Biochemical Analysis of Disease-Causing Mutations at the Kinesin-Microtubule Interface. Biophysical Journal (2018)

Chelsea KellandLauren ThorntonHana AlkhafafMadhusoodanan MottamalThomas M. Huckaba

disease-causing mutationscomputational biophysicskinesin-microtubule interfacemolecular biophysicsbiophysicsbiochemical analysiscellular physiologymedical biophysicsmembrane biologystructural biologycomputational biologyprotein scienceneurosciencebiochemistrybiophysical modeling

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Thomas Huckaba

Xavier University of Louisiana

Affiliations

Department Of Institutional Advancement

Department Of Mass Communication

Department Of Pharmacy Practice

Xavier University of Louisiana

NoneThomas Huckaba is currently serving as a Institutional Advancement faculty at Xavier University of Louisiana.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Thomas Huckaba

Xavier University of Louisiana

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Discovery of Hiv-1 Integrase Protac Degraders With Potent Activity Against Viral Infection. SSRN Electronic Journal (2026)

Abstract 2110 Catalytic Function of Lysine Deacetylase 6 is Critical for Cell Motility and Cell Division. Journal of Biological Chemistry (2025)

Lysine Deacetylases (Kdacs or Hdacs) Biological Effects Assessed by Flow Cytometry in Ht1080 Cells. Open MIND (2025)

flow cytometrybioanalysishematologylysine deacetylasesclinical biochemistrymetabolismht1080 cellsbiochemistrycell biology

Discovery of Oral Degraders of the Ros1 Fusion Protein With Potent Activity Against Secondary Resistance Mutations. Journal of Medicinal Chemistry (2024)

Lysine Deacetylase Inhibitors Have Low Selectivity in Cells and Exhibit Predominantly Off‐Target Effects. FEBS Open Bio (2024)

Kiara E. BornesMarcus A. MoodyThomas M. HuckabaMegan C. BenzEmily C. McConnellMaryam ForoozeshVan H. BarnesBridgette M. Collins‐BurowMatthew E. BurowTerry J. WattTasha B. Toro

low selectivityenzyme inhibitionpharmacologybiomedical researchbiomolecular engineeringdrug discoveryoff-target effectslysine deacetylase inhibitorsbiochemistry

Lysine Deacetylases (Kdacs or Hdacs) Biological Effects Assessed by Fixed Cell Fluorescence Microscopy in Ht1080 Cells. Open MIND (2024)

Study of Ceramide-Flavone Analogs Showing Selffluorescence and Anti-Proliferation Activities. Journal of Oncology Research and Therapy (2023)

Navneet GoyalCamilla DoMiriam Hill-OdomTeresa BeamonTulasi PonnapakkamJiawang LiuJayalakshmi SridharThomas HuckabaMaryam Foroozesh

pharmacologycancer researchoncologyceramide-flavone analogscancer treatmentanti-proliferation activities

Identification of a Modulator of the Actin Cytoskeleton, Mitochondria, Nutrient Metabolism and Lifespan in Yeast. Nature Communications (2022)

Cierra N. SingEnrique J. GarciaThomas G. LipkinThomas M. HuckabaCatherine A. TsangArielle C. CoughlinEmily J. YangIstvan R. BoldoghRyo Higuchi-SanabriaLiza A. Pon

Tube‐Like Structures Within the Ovarian Follicle of Hydrolagus Colliei Indicate the Early Origins of Follicle Cell Processes. Journal of Fish Biology (2020)

Lydia CrawfordHenry BartEnrique L. HaroldThomas M. HuckabaIan R. Davenport

fish biologyavian biologytube-like structuresbiologymammalian biologyreproductive biologyovarian follicledevelopmental biologystructural biologyfollicle cell processesgynecology

Computational and Biochemical Analysis of Disease-Causing Mutations at the Kinesin-Microtubule Interface. Biophysical Journal (2018)

Chelsea KellandLauren ThorntonHana AlkhafafMadhusoodanan MottamalThomas M. Huckaba

1
2
3
10 / page