Thomas DeCoursey

Professor

Rush University

Affiliations

Department Of Molecular Biophysics And Physiology

Rush University

Thomas Decoursey is currently serving as a Molecular Biophysics And Physiology Professor at Rush University.

Honors

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Experiences

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Education

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Thomas DeCoursey

Rush University

Professor

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physiology electrophysiology membrane biology cell biology cellular physiology molecular biology immunology neurophysiology signal transduction molecular physiology cell signaling redox biology proton channels oxidative stress immune responses human physiology proton transfer phagocytes neurons free radical biology membrane transport voltage-gated proton channels voltage-gated proton channel biophysical review cell physiology reactive oxygen species human neutrophils hyperpolarization (biology) biological chemistry mammalian biology vascular biology protein science cellular immune responses human eosinophils nadph oxidase proton channel animal physiology cellular biochemistry bioenergetics redox signaling neurotransmission ion channels membrane science neuropsychopharmacology adaptive immune system proton-exchange membrane mammalian physiology cardiovascular physiology physiological research bioluminescence selectivity filter liver physiology applied physiology experimental biology path dependence amphiphilic system neurochemistry translational physiology experimental pharmacology bioelectrochemistry anesthetic mechanism voltage-gated h+ currents hydrogen ion currents electron currents in vivo systems dimensioning and tolerancing thermally activated delayed fluorescence intermittently connected device dependently typed programming lymphatic system molecular regulation inhibitory activity voltage-gated potassium channel voltage-gated potassium channels nadph oxidase reveals voltage dependence

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Practical Guide to Voltage Gated Proton Channels With Special Focus on Their Role in the Phagocyte Respiratory Burst. (2026)

Biophysical Properties of Somatic Cancer Mutations in the S4 Transmembrane Segment of the Human Voltage-Gated Proton Channel Hhv1. Biomolecules (2025)

Interaction With Stomatin Directs Human Proton Channels Into Cholesterol-Dependent Membrane Domains. Biophysical Journal (2024)

cholesterol-dependent membrane domainsmembrane transportcell biologycell signalingproteinlipid interactionmembrane proteinsbiochemistrymembrane biologylipid movementlipidsmolecular physiologycellular biochemistry

Interior Ph-Sensing Residue of Human Voltage-Gated Proton Channel Hv1 is Histidine 168. Biophysical Journal (2024)

biophysicsbioelectronicsinterior ph-sensing residueproton transferelectrophysiologyhistidine 168biochemistryhyperpolarization (biology)

Proton Reactions: From Basic Science to Biomedical Applications. Biophysical Journal (2024)

Cholesterol Affects Voltage-Gated Proton Channels Indirectly. Biophysical Journal (2023)

voltage-gated proton channelsmembrane transportclinical lipidologyelectrophysiologybiochemistrymembranesphysiologylipids

Human Proton Channels Accumulate in Cholesterol Dependent Membrane Domains via Direct Interaction With Stomatin. bioRxiv (Cold Spring Harbor Laboratory) (2023)

membrane transportcell biologyhuman proton channelsproteinlipid interactionmembrane proteinsbiochemistrymembrane biologylipid movementphysiologylipidsdirect interactioncellular physiologymolecular physiologycellular biochemistry

Ion Channels in Immune Cells. (2023)

Transcendent Aspects of Proton Channels. Annual Review of Physiology (2023)

Don’t Dodge Retraction of Fraudulent Papers. Nature (2022)