Faculty

Institution

Unit

Venue

Thomas Biederer

Senior Scientist

Tufts University

Affiliations

Graduate School of Biomedical Sciences

Neuroscience

Thomas Biederer is currently serving as a Graduate School Of Biomedical Sciences Senior Scientist at Tufts University.

Honors

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Experiences

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Education

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Thomas Biederer

Tufts University

Senior Scientist

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neuroscience systems neuroscience neurology neurophysiology cellular neurobiology developmental biology molecular neuroscience cognitive neuroscience molecular biology neurons developmental neurobiology neuroanatomy neural circuits molecular neurobiology protein science developmental cognitive neuroscience neurochemistry cell adhesion neural science neurotransmission mammalian biology brain science visual science developmental cell nutritional neuroscience brain circuitry molecular neurodegeneration molecular regulation structural plasticity visual pathways cortical remodeling brain function neurodynamics synaptic adhesion molecule biological chemistry biomedical imaging cellular physiology ophthalmology retina molecular cell biology molecular physiology neuropsychopharmacology brain organization cell regulation genome-wide association studies genotype-phenotype association optical imaging endocrine research photoreceptor cells retina gene function synaptic cleft impulsive personality mouse striatum critical period syncam 1 coordination chemistry science advance translational psychiatry knowledge bases protein genetics medical genetics synchronization protocol transcription regulation protein expression psychiatric genetics nanobiotechnology expert-curated knowledge base synapse assembly autism spectrum disorders molecular cytogenetic analysis l-histidine decarboxylase transcellular nanoalignment synaptic function synaptic active zones alternative splicing rim-binding proteins

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Compendium of Human Gene Functions Derived From Evolutionary Modelling. Nature (2025)

Marc FeuermannHuaiyu MiPascale GaudetAnushya MuruganujanSuzanna E. LewisDustin EbertTremayne MushayahamaSuzanne A. AleksanderJames BalhoffSeth CarbonJ. Michael CherryHarold J. DrabkinNomi L. HarrisDavid P. HillRaymond LeeColin LogieSierra MoxonChristopher J. MungallPaul W. SternbergKimberly Van AukenJolene RamseyDeborah A. SiegeleRex L. ChisholmPetra FeyMichelle GiglioSuvarna NadendlaGiulia AntonazzoHelen AttrillNicholas H. BrownPhani V. GarapatiSteven MarygoldSaadullah H. AhmedPraoparn AsanitthongDiana Luna BuitragoMeltem N. ErdolMatthew C. GageSiyao HuangMohamed Ali KadhumKan Yan Chloe LiMiao LongAleksandra MichalakAngeline PesalaArmalya PritazahraShirin C. C. SaverimuttuRenzhi SuQianhan XuRuth C. LoveringJudith BlakeKaren ChristieLori CorbaniMary E. DolanLi NiDmitry SitnikovCynthia SmithManuel Lera-RamirezKim RutherfordValerie WoodPeter D’EustachioWendy M. DemosJeffrey L. De PonsMelinda R. DwinellG. Thomas HaymanMary L. KaldunskiAnne E. KwitekStanley J. F. LaulederkindJennifer R. SmithMarek A. TutajMahima VediShur-Jen WangStacia R. EngelKalpana KarraStuart R. MiyasatoRobert S. NashMarek S. SkrzypekShuai WengEdith D. WongTilmann AchselMaria Andres-AlonsoClaudia BagniÀlex BayésThomas BiedererNils BroseJohn Jia En ChuaMarcelo P. CobaL. Niels CornelisseJaime de Juan-SanzHana L. GoldschmidtEckart D. GundelfingerRichard L. HuganirCordelia ImigReinhard JahnHwajin JungPascal S. KaeserEunjoon KimFrank KoopmansMichael R. KreutzNoa LipsteinHarold D. MacGillavryPeter S. McPhersonVincent O’Connor

molecular geneticsevolutionary modellingneurosciencetheoretical biologybiological functiongene expressiondevelopmental biologyhuman gene functionsevolutionary anthropologyquantitative geneticsadaptationmolecular evolutiongenome biologysystematicsmolecular evidencefunctional genomicsgenetic basisregulatory network modellinggene functionanthropology

High-Content Image-Based Pooled Screens Reveal Regulators of Synaptogenesis. Cell Reports (2025)

developmental biologysystems neurosciencescreens reveal regulatorsdevelopmental neurobiologycellular neurobiologyneuronsmolecular neurosciencedevelopmental systemdevelopmental cellneurosciencecell research

A Complex of the Lipid Transport Er Proteins Tmem24 and C2Cd2 With Band 4.1 at Cell–Cell Contacts. The Journal of Cell Biology (2024)

Ben JohnsonMaria IulianoTuKiet T. LamThomas BiedererPietro V. De Camilli

membrane transportprotein transportcell biologyprotein scienceprotein structuremembrane proteinspharmacologymembrane biologycell and molecular biologycell-cell contactsmolecular biologyprotein functionstructural biology

Cortical Synaptic Vulnerabilities Revealed in a α-Synuclein Aggregation Model of Parkinson′S Disease. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Saroj SahAndrew D. SauerbeckJyoti GuptaDayana Pérez-AcuñaJacob E. ReiberDreson L. RussellThomas M. GoralskiMichael X. HendersonLaura A. Volpicelli-DaleyMichael J. HigleyTerrance T. KummerThomas Biederer

a-synuclein aggregation modelsystems neurosciencecognitive sciencecellular neurobiologyneural sciencebrain circuitryneuroscienceparkinson's diseasecentral nervous systembrain modelingcomputational neuroscienceneurologycognitive neurosciencecortical synaptic vulnerabilities

Transcardial Perfusion in Mice for Synaptic Evaluation and Quantification by Imaging Nanostructure (Sequin) Analysis V1. (2024)

Saroj Kumar SahThomas Biederer

transcardial perfusionsynaptic evaluationbiological imagingneuroscience

Transient Impairment in Microglial Function Causes Sex-Specific Deficits in Synaptic Maturity and Hippocampal Function in Mice Exposed to Early Adversity. Brain Behavior and Immunity (2024)

Sahabuddin AhmedBaruh PolisSumit JamwalBasavaraju G. SanganahalliZoe MacDowell KaswanRafiad IslamDana KimChristian BowersLauryn GiulianoThomas BiedererFahmeed HyderArie Kaffman

developmental neurobiologyneurosciencebrain-immune interactionmammalian biologydevelopmental cognitive neurosciencecognitive neurosciencenervous systembrain mechanismsanimal behaviorearly adversitybehavioral sciencesbehavioral neurosciencecognitive sciencebrain functionhippocampal functionneurological functionsynaptic maturitymicroglial functionpsychoneuroimmunologyneuropsychological rehabilitationneuroscience of agingsex-specific deficitsneuroimmunology

Cadm2 is Implicated in Impulsive Personality and Numerous Other Traits by Genome- and Phenome-Wide Association Studies in Humans and Mice. Translational Psychiatry (2023)

Sandra Sanchez-RoigeMariela V. JenningsHayley H. A. ThorpeJazlene E. MallariLieke C. van der WerfSevim B. BianchiYuye HuangCalvin LeeTravis T. MallardSamuel A. BarnesJin Yi WuAmanda M. Barkley-LevensonEly C. BoussatyCedric E. SnethlageDanielle SchaferZeljana BabicBoyer D. WintersKatherine E. WattersThomas BiedererStella AslibekyanAdam AutonElizabeth BabalolaRobert K. BellJessica BielenbergKatarzyna BrycEmily BullisDaniella CokerGabriel Cuellar PartidaDevika DhamijaSayantan DasTeresa FilshteinKipper Fletez-BrantWill FreymanKarl HeilbronPooja M. GandhiBarry HicksDavid A. HindsEthan M. JewettYunxuan JiangKatelyn KukarKeng-Han LinMaya LoweJey C. McCreightMatthew H. McIntyreSteven J. MichelettiMeghan E. MorenoJoanna L. MountainPriyanka NandakumarElizabeth S. NoblinJared O’ConnellAaron A. PetrakovitzG. David PoznikMorgan SchumacherAnjali J. ShastriJanie F. SheltonJingchunzi ShiSuyash ShringarpureVinh TranJoyce Y. TungXin WangWei WangCatherine H. WeldonPeter WiltonAlejandro HernandezCorinna WongChristophe Toukam TchakoutéJames MackillopDavid N. StephensSarah L. ElsonPierre FontanillasJibran Y. KhokharJared W. YoungAbraham A. Palmer

geneticsmolecular geneticshuman geneticspsychiatric geneticspopulation geneticsstatistical geneticstranslational psychiatryneurosciencegenotype-phenotype associationneurogeneticsimpulsive personalitymolecular biologygenome-wide association studies

Concerted Roles of Lrrtm1 and Syncam 1 in Organizing Prefrontal Cortex Synapses and Cognitive Functions. Nature Communications (2023)

Karen Perez de ArceAdema RibicDhrubajyoti ChowdhuryKatherine WattersGarth J. ThompsonBasavaraju G. SanganahalliElizabeth T. C. LippardAstrid RohlmannStephen M. StrittmatterMarkus MisslerFahmeed HyderThomas Biederer

prefrontal cortex synapsessystems neurosciencecognitive functionsbrain organizationneurosciencecentral nervous systemcognitive neuroscience

Or04-01-23 Low Vitamin K Intake Negatively Affects Cognition and Hippocampal Neurogenesis in C57 Bl6 Mice. Current Developments in Nutrition (2023)

Shannon MarschallTong ZhengXueyan FuXiaohua ShenDonald SmithAndrew TarrKathryn MykytenThomas BiedererBarbara Shukitt-HaleSarah Booth

hippocampal neurogenesisgeneticsclinical nutritionnutritionnutrient physiologyhuman nutritionneurosciencephysiologyanimal nutritionnutritional neurosciencenutritional sciencescognitive neuroscienceexperimental nutrition

P27-026-23 in Vitro Effects of Myo-Inositol Supplementation on Adult Human Neural Progenitor Cells. Current Developments in Nutrition (2023)

Kathryn MykytenThomas BiedererDerek FisherTong Zheng

clinical nutritionin vitro toxicologycell biologynutritionfood sciencenutrient physiologyvitro effectspharmacologymyo-inositol supplementationanimal nutritionnutritional biochemistrynutritional sciencespersonalized nutritionagricultural economicsexperimental nutrition

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Thomas Biederer

Senior Scientist

Tufts University

Affiliations

Graduate School of Biomedical Sciences

Neuroscience

Thomas Biederer is currently serving as a Graduate School Of Biomedical Sciences Senior Scientist at Tufts University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Thomas Biederer

Tufts University

Senior Scientist

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Compendium of Human Gene Functions Derived From Evolutionary Modelling. Nature (2025)

High-Content Image-Based Pooled Screens Reveal Regulators of Synaptogenesis. Cell Reports (2025)

A Complex of the Lipid Transport Er Proteins Tmem24 and C2Cd2 With Band 4.1 at Cell–Cell Contacts. The Journal of Cell Biology (2024)

Ben JohnsonMaria IulianoTuKiet T. LamThomas BiedererPietro V. De Camilli

Cortical Synaptic Vulnerabilities Revealed in a α-Synuclein Aggregation Model of Parkinson′S Disease. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Transcardial Perfusion in Mice for Synaptic Evaluation and Quantification by Imaging Nanostructure (Sequin) Analysis V1. (2024)

Saroj Kumar SahThomas Biederer

transcardial perfusionsynaptic evaluationbiological imagingneuroscience

Transient Impairment in Microglial Function Causes Sex-Specific Deficits in Synaptic Maturity and Hippocampal Function in Mice Exposed to Early Adversity. Brain Behavior and Immunity (2024)

Sahabuddin AhmedBaruh PolisSumit JamwalBasavaraju G. SanganahalliZoe MacDowell KaswanRafiad IslamDana KimChristian BowersLauryn GiulianoThomas BiedererFahmeed HyderArie Kaffman

Cadm2 is Implicated in Impulsive Personality and Numerous Other Traits by Genome- and Phenome-Wide Association Studies in Humans and Mice. Translational Psychiatry (2023)

Concerted Roles of Lrrtm1 and Syncam 1 in Organizing Prefrontal Cortex Synapses and Cognitive Functions. Nature Communications (2023)

prefrontal cortex synapsessystems neurosciencecognitive functionsbrain organizationneurosciencecentral nervous systemcognitive neuroscience

Or04-01-23 Low Vitamin K Intake Negatively Affects Cognition and Hippocampal Neurogenesis in C57 Bl6 Mice. Current Developments in Nutrition (2023)

Shannon MarschallTong ZhengXueyan FuXiaohua ShenDonald SmithAndrew TarrKathryn MykytenThomas BiedererBarbara Shukitt-HaleSarah Booth

P27-026-23 in Vitro Effects of Myo-Inositol Supplementation on Adult Human Neural Progenitor Cells. Current Developments in Nutrition (2023)

Kathryn MykytenThomas BiedererDerek FisherTong Zheng

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