Faculty

Institution

Unit

Venue

Terry J. Watt

Associate Professor

Xavier University of Louisiana

Affiliations

Department Of Chemistry

Department Of Institutional Advancement

Xavier University of Louisiana

Terry J. Watt is currently serving as a Chemistry Associate Professor at Xavier University of Louisiana.

Honors

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Experiences

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Education

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Terry J. Watt

Xavier University of Louisiana

Associate Professor

You can click a keyword to filter the displayed items

biochemistry enzymes molecular biology biological chemistry chemical biology enzyme specificity biochemical sciences enzymatic modification enzyme inhibition protein science enzyme catalysis biophysical chemistry structural biology protein chemistry structural molecular biology biochemical genetics cellular biochemistry structure-function enzyme kinetics biomolecular engineering biotechnology laboratory investigation molecular basis biological engineering biochemical engineering protein engineering molecular science inhibitory activity cellular enzymology laboratory methods metalloproteins protein function biomolecular interactions fluorophore conjugation gene expression biomolecules process biochemistry ima fungus microbial cell factory nucleic acids biomedical informatics bioenergetics biotechnology advance peptide engineering biomolecular tools analytical biotechnology yeast gene recognition sequence analysis food digestion laboratory protocols off-target effects biomedical research bioactive metal protein expression purification method protein purification catabolism protein transport structure elucidation project-based learning laboratory management substrate classes critical review label-free deacetylation assay t4 lysozyme activity activity profiles due large classes high basal velocity finding exact sequences restriction enzyme digests inquiry‐based experiments large‐scale introduction low selectivity lysine deacetylase inhibitors negative selection residues following acetyllysine

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 1636 Molecular Interactions Determining the Specificity of a Lysine Deacetylase. Journal of Biological Chemistry (2025)

structural molecular biologybiophysical chemistryenzymeschemical biologymolecular biologylysine deacetylaseabstract 1636biochemistrybiological chemistryprotein structuremolecular interactionsbiochemical geneticsenzymatic modificationenzyme specificitymolecular metabolismprotein chemistrybiochemical sciencesstructure-function enzyme kineticsenzyme inhibition

Abstract 2110 Catalytic Function of Lysine Deacetylase 6 is Critical for Cell Motility and Cell Division. Journal of Biological Chemistry (2025)

enzymatic modificationenzyme specificityenzymesabstract 2110molecular metabolismenzyme catalysiscell biologycatalytic functionbiochemistrycell divisionchemical biologybiological chemistrycellular enzymologyenzyme inhibitioncellular biochemistry

Lysine Deacetylase Inhibitors Have Low Selectivity in Cells and Exhibit Predominantly Off‐Target Effects. FEBS Open Bio (2024)

Kiara E. BornesMarcus A. MoodyThomas M. HuckabaMegan C. BenzEmily C. McConnellMaryam ForoozeshVan H. BarnesBridgette M. Collins‐BurowMatthew E. BurowTerry J. WattTasha B. Toro

lysine deacetylase inhibitorsoff-target effectsbiomedical researchlow selectivitybiochemistrypharmacologydrug discoveryenzyme inhibitionbiomolecular engineering

Abstract 2048: Enzyme-Substrate Interactions Driving Lysine Deacetylase Specificity. Journal of Biological Chemistry (2023)

enzymatic modificationenzyme specificityenzymesmolecular metabolismprotein scienceenzyme catalysisbiochemistryabstract 2048biochemical sciencesmolecular biologybiological chemistryenzyme inhibition

Abstract 2073: Resolving Substrate Specificity of Metal Dependent Lysine Deacetylases. Journal of Biological Chemistry (2023)

enzyme specificityenzymesprotein chemistryprotein scienceenzyme catalysisbiochemistryenzyme inhibitionchemical biologybiochemical sciencesmolecular biologybiological chemistryprotein structureabstract 2073metalloproteinsbiophysical chemistry

Abstract 2074: Kdac-Substrate Specificity in Cellular Context. Journal of Biological Chemistry (2023)

molecular and cellular biologycell biologyabstract 2074molecular cell biologyprotein transportmolecular biologysignal transductioncellular biochemistry

Abstract 2196: Determining the Substrates of Kdac4 and Kdac7. Journal of Biological Chemistry (2023)

abstract 2196biomolecular structuremolecular sciencebiochemistrystructure elucidationmolecular basisbiochemical sciencesprotein structuremolecular structurestructural biology

Endogenous Expression of Inactive Lysine Deacetylases Reveals Deacetylation-Dependent Cellular Mechanisms. PLoS ONE (2023)

molecular and cellular biologybiochemical geneticsinactive lysineenzymesmolecular metabolismcell signalingcell biologybiochemistrycell metabolismbiological chemistryenzyme inhibitioncellular biochemistrycatabolism

Lysine Deacetylase Substrate Selectivity: Distinct Interaction Surfaces Drive Positive and Negative Selection for Residues Following Acetyllysine. Biochemistry (2023)

enzymatic modificationenzyme specificityenzymesresidues following acetyllysineprotein chemistryprotein scienceenzyme catalysisnegative selectionbiochemistryenzyme inhibitionchemical biologymolecular biologybiophysical chemistry

Identifying Substrates of Kdac6. The FASEB Journal (2022)

molecular characterizationbiochemistrychemical biologymolecular basismolecular biologyprotein structurestructural molecular biologystructural biology

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Terry J. Watt

Associate Professor

Xavier University of Louisiana

Affiliations

Department Of Chemistry

Department Of Institutional Advancement

Xavier University of Louisiana

Terry J. Watt is currently serving as a Chemistry Associate Professor at Xavier University of Louisiana.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Terry J. Watt

Xavier University of Louisiana

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 1636 Molecular Interactions Determining the Specificity of a Lysine Deacetylase. Journal of Biological Chemistry (2025)

Abstract 2110 Catalytic Function of Lysine Deacetylase 6 is Critical for Cell Motility and Cell Division. Journal of Biological Chemistry (2025)

Lysine Deacetylase Inhibitors Have Low Selectivity in Cells and Exhibit Predominantly Off‐Target Effects. FEBS Open Bio (2024)

Kiara E. BornesMarcus A. MoodyThomas M. HuckabaMegan C. BenzEmily C. McConnellMaryam ForoozeshVan H. BarnesBridgette M. Collins‐BurowMatthew E. BurowTerry J. WattTasha B. Toro

lysine deacetylase inhibitorsoff-target effectsbiomedical researchlow selectivitybiochemistrypharmacologydrug discoveryenzyme inhibitionbiomolecular engineering

Abstract 2048: Enzyme-Substrate Interactions Driving Lysine Deacetylase Specificity. Journal of Biological Chemistry (2023)

enzymatic modificationenzyme specificityenzymesmolecular metabolismprotein scienceenzyme catalysisbiochemistryabstract 2048biochemical sciencesmolecular biologybiological chemistryenzyme inhibition

Abstract 2073: Resolving Substrate Specificity of Metal Dependent Lysine Deacetylases. Journal of Biological Chemistry (2023)

Abstract 2074: Kdac-Substrate Specificity in Cellular Context. Journal of Biological Chemistry (2023)

molecular and cellular biologycell biologyabstract 2074molecular cell biologyprotein transportmolecular biologysignal transductioncellular biochemistry

Abstract 2196: Determining the Substrates of Kdac4 and Kdac7. Journal of Biological Chemistry (2023)

abstract 2196biomolecular structuremolecular sciencebiochemistrystructure elucidationmolecular basisbiochemical sciencesprotein structuremolecular structurestructural biology

Endogenous Expression of Inactive Lysine Deacetylases Reveals Deacetylation-Dependent Cellular Mechanisms. PLoS ONE (2023)

Lysine Deacetylase Substrate Selectivity: Distinct Interaction Surfaces Drive Positive and Negative Selection for Residues Following Acetyllysine. Biochemistry (2023)

Identifying Substrates of Kdac6. The FASEB Journal (2022)

molecular characterizationbiochemistrychemical biologymolecular basismolecular biologyprotein structurestructural molecular biologystructural biology

1
2
3
4
5
10 / page