Faculty

Institution

Unit

Venue

Ted S. Acott

Oregon Health & Science University

Affiliations

OHSU School of Medicine

Department Of Ophthalmology

Institute Of Casey Eye

Oregon Health & Science University

Ted S. Acott is a Senior Professor at Oregon Health & Science University. His research integrates ophthalmology, biomechanics, and cell biology, focusing on the trabecular meshwork and the mechanobiology of glaucoma. Recent work employs traction force microscopy and advanced imaging to elucidate how matrix stiffness, cytoskeletal dynamics, and actin-microtubule synergy drive collagen reorganization and aqueous humor outflow resistance. His 2025 publications also address aging effects on ocular biomechanics and develop iPSC-based protocols for trabecular meshwork cell replacement.

Honors

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Experiences

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Education

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Ted S. Acott

Oregon Health & Science University

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ophthalmology cell biology trabecular meshwork glaucoma matrix biology biomedical engineering cellular physiology mechanobiology extracellular matrix biomechanics visual science molecular biology tissue (biology) ocular surface molecular cell biology cell-matrix interactions ophthalmology retina cell biomechanics cell research trabecular meshwork cells ocular disease mechanotransduction retina ocular tissues experimental ophthalmology human genetics ocular pathology stem cell research vision research signaling pathways outflow facility neuro-ophthalmology visual system vascular biology reproductive biology human trabecular meshwork genetic disorders cell regulation reproductive science fertilisation medical genetics genome biology reproductive physiology protein expression aqueous humour anatomical model ocular surface physiology biomedical modeling oculoplastics tissue physiology human tissues matrix metalloproteinases age-related macular degeneration reproductive medicine biofabrication orthopaedic research disease gene identification semen analysis metalloproteins mechanical stretching mechanical science eye health treatment and prevention gametes tissue culture soft tissue reconstruction intraocular pressure regulation extracellular matrix turnover trabecular matrix metalloproteinases extended families caudal epididymal fluid bovine spermatozoa perfusion organ culture open-angle glaucoma segmental regions human retina

Notable Scholarly Works

Notable Federal Grants

Collaborators

3D Traction Force Microscopy in Human Trabecular Meshwork Tissues: Effects of Rock and Yap/Taz Inhibition in Normal and Glaucomatous Tissues. Tissue and Cell (2025)

biophysicsyap/taz inhibitionmatrix biologyocular tissuescell biomechanicsglaucomatous tissuesocular surfacetissue physiologybiomedical engineeringmechanobiologyophthalmology retinaophthalmologytissue (biology)traction force microscopytrabecular meshworkglaucoma

Actin-Microtubule Synergy Dominates Force Transmission and Collagen Strain in Human Trabecular Meshwork. Acta Biomaterialia (2025)

biophysicsactin-microtubule synergy dominatesmatrix biologycell biomechanicscell biologycellular physiologycellular structuremechanotransductionbiomedical engineeringmolecular motorsmechanobiologycytoskeletoncollagen straincell motilityhuman trabecular meshworkbiomechanics

Impact of Aging on Anterior Segment Morphology and Aqueous Humor Dynamics in Human Eyes: Advanced Imaging and Computational Techniques. Journal of Applied Biomedicine (2025)

aqueous humor dynamicsadvanced imagingretinaneuro-ophthalmologyocular tissuesvision researchanterior segment morphologybiomedical engineeringvisual systemophthalmology retinaaqueous humourophthalmologyvisual scienceglaucoma

Matrix Stiffness Regulates Traction Forces, Cytoskeletal Dynamics, and Collagen Reorganization in Trabecular Meshwork Cells in Glaucoma. Matter (2025)

collagen reorganizationmatrix biologycell-matrix interactionscell biomechanicscell biologycellular physiologymechanotransductioncytoskeletonmatrix stiffnessmechanobiologytraction forcesophthalmologytrabecular meshworkbiomechanics

Protocols for Tm Cell Replacement Using Differentiated Tm-Like Induced Pluripotent Stem Cells (Ipsc). BENTHAM SCIENCE PUBLISHERS eBooks (2025)

regenerative medicinecellular differentiationstem cell researchstem-cell therapystem cellscell biologycellular therapybiomedical engineeringcell engineeringinduced pluripotent stem cellstissue engineering

Quantitative Measurements of Stromal and Epithelial Riboflavin With a Novel Transepithelial High-Concentration Riboflavin Soak-And-Rinse Protocol. Translational Vision Science & Technology (2025)

epithelial riboflavinquantitative measurementschromatographybiochemistrybioanalysis

Response to “Scientific Concerns About Recent Fluid-Structure Interaction Models of the Aqueous Humor Outflow Pathway”. Investigative Ophthalmology & Visual Science (2025)

biophysicsfluid flowfluid dynamicsfluid-solid interactionsscientific concernsfluid mechanicsfluid sciencesystems biologybiofluid dynamics

Comparative Analysis of Traction Forces in Normal and Glaucomatous Trabecular Meshwork Cells Within a 3D, Active Fluid-Structure Interaction Culture Environment. Acta Biomaterialia (2024)

Alireza KarimiMini AgaTaaha KhanSiddharth Daniel D'costaOmkar ThawareElizabeth WhiteMary J. KelleyHaiyan GongTed S. Acott

cell biomechanicsmechanical engineeringmechanical sciencebiomedical engineeringmaterials sciencetraction forcesbiomaterialstissue engineeringbiomechanics

Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches. Investigative Ophthalmology & Visual Science (2024)

Ted S. AcottMichael P. FautschWeiming MaoC. Ross EthierAlex S. HuangMary J. KelleyMini AgaSanjoy K. BhattacharyaTerete BorrasDiane BovenkampUttio Roy ChowdhuryAbbot F. ClarkMohammed I. DibasYiqin DuMichael H. ElliottJennifer A. FaralliHaiyan GongSamuel HerbergMurray A. JohnstonePaul L. KaufmanKate E. KellerRuth A. KellyDavid KrizajMarkus H. KuehnHoi Lam LiRaquel LiebermanShan C. LinYutao LiuFiona S. McDonnellColleen M. McDowellGillian J. McLellanPhilip MzykKayarat Saidas NairDarryl R. OverbyDonna M. PetersVijayKrishna RaghunathanPonugoti Vasantha RaoGavin W. RoddyNajam A. SharifMyoung Sup ShimYang SunBenjamin R. ThomsonCarol B. TorisColin E. WilloughbyHao F. ZhangThomas F. FreddoRudolf FuchshoferKamisha R. HillAlireza KarimiKrishnakumar KizhatilCasey C. KopcyznskiPaloma LitonGaurang PatelMichael PengPadmanabhan P. PattabiramanGanesh PrasannaEster Reina-TorresE. Griffen SamplesJohn R. SamplesCynthia L. SteelClemens A. StrohmaierPreeti SubramanianChenna Kesavulu SugaliJoseph van Batenburg-SherwoodCydney WongHannah YoungbloodGulab S. ZodeElizabeth WhiteW. Daniel Stamer

medical optical imagingintraocular pressure regulationexperimental ophthalmologyocular tissuesocular surfacevision researchoutflow facilityocular surface physiologyophthalmologyvisual science

Consensus Recommendations for Trabecular Meshwork Cell Isolation, Characterization and Culture. UNC Libraries (2024)

biological engineeringmatrix biologyconsensus recommendationscell manipulationcell culturebiomedical engineeringcell researchtissue (biology)tissue engineeringtissue culture

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Ted S. Acott

Oregon Health & Science University

Affiliations

OHSU School of Medicine

Department Of Ophthalmology

Institute Of Casey Eye

Oregon Health & Science University

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Ted S. Acott

Oregon Health & Science University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

3D Traction Force Microscopy in Human Trabecular Meshwork Tissues: Effects of Rock and Yap/Taz Inhibition in Normal and Glaucomatous Tissues. Tissue and Cell (2025)

Actin-Microtubule Synergy Dominates Force Transmission and Collagen Strain in Human Trabecular Meshwork. Acta Biomaterialia (2025)

Impact of Aging on Anterior Segment Morphology and Aqueous Humor Dynamics in Human Eyes: Advanced Imaging and Computational Techniques. Journal of Applied Biomedicine (2025)

Matrix Stiffness Regulates Traction Forces, Cytoskeletal Dynamics, and Collagen Reorganization in Trabecular Meshwork Cells in Glaucoma. Matter (2025)

Protocols for Tm Cell Replacement Using Differentiated Tm-Like Induced Pluripotent Stem Cells (Ipsc). BENTHAM SCIENCE PUBLISHERS eBooks (2025)

Quantitative Measurements of Stromal and Epithelial Riboflavin With a Novel Transepithelial High-Concentration Riboflavin Soak-And-Rinse Protocol. Translational Vision Science & Technology (2025)

epithelial riboflavinquantitative measurementschromatographybiochemistrybioanalysis

Response to “Scientific Concerns About Recent Fluid-Structure Interaction Models of the Aqueous Humor Outflow Pathway”. Investigative Ophthalmology & Visual Science (2025)

biophysicsfluid flowfluid dynamicsfluid-solid interactionsscientific concernsfluid mechanicsfluid sciencesystems biologybiofluid dynamics

Comparative Analysis of Traction Forces in Normal and Glaucomatous Trabecular Meshwork Cells Within a 3D, Active Fluid-Structure Interaction Culture Environment. Acta Biomaterialia (2024)

Alireza KarimiMini AgaTaaha KhanSiddharth Daniel D'costaOmkar ThawareElizabeth WhiteMary J. KelleyHaiyan GongTed S. Acott

cell biomechanicsmechanical engineeringmechanical sciencebiomedical engineeringmaterials sciencetraction forcesbiomaterialstissue engineeringbiomechanics

Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches. Investigative Ophthalmology & Visual Science (2024)

medical optical imagingintraocular pressure regulationexperimental ophthalmologyocular tissuesocular surfacevision researchoutflow facilityocular surface physiologyophthalmologyvisual science

Consensus Recommendations for Trabecular Meshwork Cell Isolation, Characterization and Culture. UNC Libraries (2024)

biological engineeringmatrix biologyconsensus recommendationscell manipulationcell culturebiomedical engineeringcell researchtissue (biology)tissue engineeringtissue culture

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10 / page