Faculty

Institution

Unit

Venue

Sue A. Aicher

Professor of Chemical Physiology and Biochemistry Neuroscience Graduate Program Graduate Program in Biomedical Sciences

Oregon Health & Science University

Affiliations

OHSU School of Medicine

Bob And Charlee Moore Institute For Nutrition And Wellness

Center Of The Amyloidosis

Division Of Cardiology

Department Of Physiology And Pharmacology

Oregon Health & Science University

Bob And Charlee Moore Institute For Nutrition And Wellness

School Of Medicine

Division Of Cardiology

School Of Medicine

Sue A. Aicher is a Professor of Chemical Physiology and Biochemistry at Oregon Health & Science University, affiliated with the Neuroscience Graduate Program and the Graduate Program in Biomedical Sciences. Her research integrates cellular neurobiology, neuroanatomy, and neurophysiology to investigate neural mechanisms underlying pain, sensory processing, and neurodegeneration. Recent work focuses on corneal innervation and ocular surface biology, including sex differences in photophobic behaviors following cortical spreading depression and tear proteome biomarkers for persistent post-refractive surgery pain. She also studies remyelination-mediated neuroprotection via DLK signaling, perineuronal nets in cocaine relapse memory, and cardiac sympathetic innervation in heart failure. Her contributions include leadership in a National Eye Institute U01-funded consortium on ocular surface innervation, reflecting her translational impact in ophthalmology and neuroscience.

Honors

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Experiences

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Education

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Sue A. Aicher

Oregon Health & Science University

Professor of Chemical Physiology and Biochemistry Neuroscience Graduate Program Graduate Program in Biomedical Sciences

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neuroscience neurophysiology neurology neuroanatomy physiology nervous system neurons pharmacology neuropharmacology central nervous system systems neuroscience neuropsychopharmacology ocular surface neurotransmission cellular neurobiology receptors pain research mammalian biology neurochemistry pain mechanism cellular physiology pharmacological research neural science brain circuitry pain medicine visual science spinal cord brain science experimental ophthalmology molecular neurobiology molecular physiology addiction biology brain function ocular tissues molecular cell biology circulatory physiology pharmacotherapy animal physiology neuromodulation (medicine) neurodynamics neurotransmitters opioid use disorder molecular pain neuropeptide receptors ocular disease rostral ventromedial medulla perineuronal nets nucleus tractus solitarii corneal abrasion addictive behaviors neuroinflammation clinical neuroscience behavioural pharmacology experimental pharmacology visual pathways lacrimal gland neurotology neuropathic pain mu-opioid receptors fast-spiking interneurons m-opioid receptors functional adaptations cocaine memory reactivation female rats cerebrovascular disease brain mechanisms brain modeling energy homeostasis hyperpolarization (biology) cancer biology cerebellar contribution global brain ischemia gabaergic neurons arcuate nucleus male mice optogenetic stimulation

Notable Scholarly Works

Notable Federal Grants

Collaborators

Corneal Innervation Research at a Crossroads: A Tool-Driven Roadmap for the Future Nbsp; Br I Consensus by the National Eye Institute, U01-Funded Consortium on Ocular Surface Innervation /I. SSRN Electronic Journal (2026)

keratoconusocular surface physiologyocular tissuesophthalmologyvision rehabilitationtissue (biology)confocal microscopyvisual systemvisual sciencecorneal innervation researchtool-driven roadmapocular surfacecorneal dystrophybiomedical engineeringocular surface innervation

Cornea Specialists Are the Highest Opioid Prescribers at a Large Academic Eye Institute in the USA. BMJ Open Ophthalmology (2025)

medicineophthalmologyvision rehabilitationoptometryocular surface

Differences in Pre-Surgical Baseline Tear Proteome Are Associated With Persistent Post-Refractive Surgery Pain. The Ocular Surface (2025)

pre-surgical baselineocular surface physiologyvitreous bodyocular surfaceophthalmologyophthalmology retinamicrosurgerysurgerypain managementwound healing

Sex Differences in Photophobic Behaviors Following Cortical Spreading Depression in Rats. Cephalalgia (2025)

Manvir KaurNicholas A. WardKelly L. KarlageCatherine W. MorgansSue A. AicherTally M. Largent-Milnes

biological psychiatryneurosciencepsychologyphotophobic behaviorsbehavioral sciencesdepressionbehavioral neuroscience

Activating Transcription Factor 3 (Atf3) and Calcitonin Gene-Related Peptide (Cgrp) Increase in Trigeminal Ganglion Neurons in Female Rats After Photorefractive Keratectomy (Prk)-Like Corneal Abrasion. Neurobiology of Pain (2024)

Clem GunterCody L JiangShae O ZeimantzDeborah M HegartyCatherine W MorgansTally M Largent-MilnesSue A Aicher

spinal cordcalcitonin gene-related peptideneuronsneurophysiologyphotorefractive keratectomyneuroradiologyneurosciencemolecular neurobiologymolecular physiologycentral nervous systemneuropeptidesmolecular neurosciencefemale ratsexperimental ophthalmologycorneal abrasionocular surfacecorneal dystrophyneurochemistrymolecular biologyneuroanatomysystems biologypeptidestrigeminal ganglion neurons

Hypertension-Induced Heart Failure Disrupts Cardiac Sympathetic Innervation. American Journal of Physiology-Heart and Circulatory Physiology (2024)

Arianna ScalcoEthan N. LeeMorgan A. JohnsonMichelle L. SorensenThomas N. HiltonRiley K. OmonakaShae ZeimantzSue A. AicherWilliam R. WoodwardBeth A. Habecker

cardiovascular physiologyhypertensionhypertension-induced heart failurecardiologycirculatory physiologycardiac sympathetic innervationheart failurephysiology

Perineuronal Nets in the Rat Medial Prefrontal Cortex Alter Hippocampal–Prefrontal Oscillations and Reshape Cocaine Self-Administration Memories. Journal of Neuroscience (2024)

Jereme C. WingertJonathan D. RamosSebastian X. ReynoldsAngela E. GonzalezR. Mae RoseDeborah M. HegartySue A. AicherLydia G. BaileyTravis E. BrownAtheir I. AbbasBarbara A. Sorg

pharmacologyneurologybrain circuitryneurodynamicsneuroscienceanimal cognitionbrain scienceneurochemistryperineuronal netsneuroanatomyneural sciencesystems neuroscienceneuropharmacologyneurophysiologycognitive neuroscience

Prospective Cohort Study Investigating Frequency and Risk Factors for Acute Pain 1 Day After Refractive Surgery. BMJ Open Ophthalmology (2024)

Jason BetzElyana Vittoria Tessa LocatelliBrooke M HarknessMaricarmen Perez-BlancoSteven J EveristSiting ChenRichard StutzmanWinston ChamberlainAfshan NanjiJodi LapidusSue A AicherAnat Galor

refractive surgeryprospective cohort studiesretrospective cohort studiesophthalmologyacute painrisk factorssurvival analysiscohort studies

Remyelination Protects Neurons From Dlk-Mediated Neurodegeneration. Nature Communications (2024)

Greg J. DuncanSam D. IngramKatie EmberleyJo HillChristian CordanoAhmed AbdelhakMichael McCaneJennifer E. JenksNora JabassiniKirtana AnanthSkylar J. FerraraBrittany StedelinBenjamin SivyerSue A. AicherThomas S. ScanlanTrent A. WatkinsAnusha MishraJonathan W. NelsonAri J. GreenBen Emery

dlk-mediated neurodegenerationneuroscienceneuronsneuroprotectionneurodegenerative diseasesremyelination protects neurons

Tear Proteins Altered in Patients With Persistent Eye Pain After Refractive Surgery: Biomarker Candidate Discovery. Journal of Proteome Research (2024)

Brooke M. HarknessSiting ChenKilsun KimAshok P. ReddyTrevor J. McFarlandDeborah M. HegartySteven J. EveristJulie A. SaugstadJodi LapidusAnat GalorSue A. Aicher

refractive surgeryocular diseasebiomarker discoverybiophysicspersistent eye painproteomicsophthalmologybiomarkersclinical proteomicsproteome researchbiomarker candidate discoverytear proteinsdermatologytranslational proteomicsprotein science

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Sue A. Aicher

Professor of Chemical Physiology and Biochemistry Neuroscience Graduate Program Graduate Program in Biomedical Sciences

Oregon Health & Science University

Affiliations

OHSU School of Medicine

Bob And Charlee Moore Institute For Nutrition And Wellness

Center Of The Amyloidosis

Division Of Cardiology

Department Of Physiology And Pharmacology

Oregon Health & Science University

Bob And Charlee Moore Institute For Nutrition And Wellness

School Of Medicine

Division Of Cardiology

School Of Medicine

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Sue A. Aicher

Oregon Health & Science University

Professor of Chemical Physiology and Biochemistry Neuroscience Graduate Program Graduate Program in Biomedical Sciences

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cornea Specialists Are the Highest Opioid Prescribers at a Large Academic Eye Institute in the USA. BMJ Open Ophthalmology (2025)

medicineophthalmologyvision rehabilitationoptometryocular surface

Differences in Pre-Surgical Baseline Tear Proteome Are Associated With Persistent Post-Refractive Surgery Pain. The Ocular Surface (2025)

pre-surgical baselineocular surface physiologyvitreous bodyocular surfaceophthalmologyophthalmology retinamicrosurgerysurgerypain managementwound healing

Sex Differences in Photophobic Behaviors Following Cortical Spreading Depression in Rats. Cephalalgia (2025)

Manvir KaurNicholas A. WardKelly L. KarlageCatherine W. MorgansSue A. AicherTally M. Largent-Milnes

biological psychiatryneurosciencepsychologyphotophobic behaviorsbehavioral sciencesdepressionbehavioral neuroscience

Clem GunterCody L JiangShae O ZeimantzDeborah M HegartyCatherine W MorgansTally M Largent-MilnesSue A Aicher

Hypertension-Induced Heart Failure Disrupts Cardiac Sympathetic Innervation. American Journal of Physiology-Heart and Circulatory Physiology (2024)

Arianna ScalcoEthan N. LeeMorgan A. JohnsonMichelle L. SorensenThomas N. HiltonRiley K. OmonakaShae ZeimantzSue A. AicherWilliam R. WoodwardBeth A. Habecker

cardiovascular physiologyhypertensionhypertension-induced heart failurecardiologycirculatory physiologycardiac sympathetic innervationheart failurephysiology

Perineuronal Nets in the Rat Medial Prefrontal Cortex Alter Hippocampal–Prefrontal Oscillations and Reshape Cocaine Self-Administration Memories. Journal of Neuroscience (2024)

Jereme C. WingertJonathan D. RamosSebastian X. ReynoldsAngela E. GonzalezR. Mae RoseDeborah M. HegartySue A. AicherLydia G. BaileyTravis E. BrownAtheir I. AbbasBarbara A. Sorg

Prospective Cohort Study Investigating Frequency and Risk Factors for Acute Pain 1 Day After Refractive Surgery. BMJ Open Ophthalmology (2024)

Jason BetzElyana Vittoria Tessa LocatelliBrooke M HarknessMaricarmen Perez-BlancoSteven J EveristSiting ChenRichard StutzmanWinston ChamberlainAfshan NanjiJodi LapidusSue A AicherAnat Galor

refractive surgeryprospective cohort studiesretrospective cohort studiesophthalmologyacute painrisk factorssurvival analysiscohort studies

Remyelination Protects Neurons From Dlk-Mediated Neurodegeneration. Nature Communications (2024)

dlk-mediated neurodegenerationneuroscienceneuronsneuroprotectionneurodegenerative diseasesremyelination protects neurons

Tear Proteins Altered in Patients With Persistent Eye Pain After Refractive Surgery: Biomarker Candidate Discovery. Journal of Proteome Research (2024)

Brooke M. HarknessSiting ChenKilsun KimAshok P. ReddyTrevor J. McFarlandDeborah M. HegartySteven J. EveristJulie A. SaugstadJodi LapidusAnat GalorSue A. Aicher

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