Faculty

Institution

Unit

Venue

Steven Fliesler

SUNY Distinguished Professor; Meyer H Riwchun Endowed Chair Professor Vice-Chair and Director of Research Professor

University at Buffalo

Affiliations

Jacobs School of Medicine and Biomedical Sciences

Ophthalmology

Steven Fliesler is currently serving as a Jacobs School Of Medicine And Biomedical Sciences SUNY Distinguished Professor; Meyer H Riwchun Endowed Chair Professor Vice-Chair and Director of Research Professor at University At Buffalo.

Honors

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Experiences

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Education

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Steven Fliesler

University at Buffalo

SUNY Distinguished Professor; Meyer H Riwchun Endowed Chair Professor Vice-Chair and Director of Research Professor

You can click a keyword to filter the displayed items

ophthalmology genetics membrane biology retina vascular biology mammalian biology neuroscience smith-lemli-opitz syndrome molecular biology experimental ophthalmology visual science vision research gene expression protein science rat model neuro-ophthalmology lipids structural biology retinal degeneration experimental medicine avian biology liver physiology lipid science cardiovascular research molecular and cellular biology redox biology regenerative medicine molecular physiology lipoprotein metabolism medical genetics oxysterol membranes biological chemistry lipid analysis ocular disease biochemical sciences membrane science clinical lipidology cellular physiology cellular biology lipid disorders membrane transport lipid chemistry hyperlipidemia neurochemistry experiment design steroid metabolism photoreceptor cells genome biology proteinlipid interaction experimental testing protein expression experimental biology cellular neurobiology vertebrate retina retinal function rat retina glycosylation vertebrate vision photobiology cell regulation cholesterol homeostasis mouse model retinitis pigmentosa transgenic mice rodent model cerebrovascular disease dyslipidemia nanobiotechnology human sciences gene regulation endoplasmic reticulum stress membrane morphogenesis human retina loss-of-function phenotype cholesterol deficiency apoptosis cell biology autophagy glaucoma cholesterol metabolism molecular neurodegeneration cell metabolism cell death

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bottlenecks in the Investigation of Retinal Sterol Homeostasis. Biomolecules (2024)

Sriganesh Ramachandra RaoSteven J. Fliesler

biophysicscardiovascular researchvascular biologyretinaretinal sterol homeostasismembrane biologymolecular biologyophthalmology

Inherited Retinal Degeneration Caused by Dehydrodolichyl Diphosphate Synthase Mutation–Effect of an Alg6 Modifier Variant. International Journal of Molecular Sciences (2024)

Elisha MonsonArtur V. CideciyanAlejandro J. RomanAlexander SumarokaMalgorzata SwiderVivian WuIryna ViarbitskayaSamuel G. JacobsonSteven J. FlieslerSteven J. Pittler

genetic engineeringhematologymolecular sciencegenetic variationallelic variantocular diseasemolecular biologyretinal degenerationhuman geneticsophthalmologygenetics

The Subretinal Drusenoid Deposit (Sdd) of Age-Related Macular Degeneration (Amd) May Have a Specific and Strong Association With High-Risk Vascular Diseases (Hrvds). Asia-Pacific Journal of Ophthalmology (2024)

Steven J. Fliesler

clinical otolaryngologyimmunologystem cellsneuroscienceneuromuscular medicineage-related macular degenerationneurovascular diseasestrabecular meshworkvascular biologyalzheimer's diseasehigh-risk vascular diseasesatherosclerosisoculoplasticshealth sciencessubretinal drusenoid depositcorneal dystrophystrokecardiovascular researchaging cellocular tissuesvascular surgery

Transcriptomic Analysis of Genes Associated With Nucleic Acid and Histone Methylation and One-Carbon Metabolism in a Mouse Cone Photoreceptor-Derived Cell Line Treated With 7-Dehydrocholesterol-Derived Oxysterols. Essentials in ophthalmology/Essentials ophthalmology (2024)

Bruce A. PfefferSteven J. Fliesler

histone methylationvascular biologyphotoreceptor cellsexperimental ophthalmologyneuro-ophthalmologycell biologynucleic acidsmolecular evidencecell metabolismtranscriptomic analysismolecular cell biologymolecular biologychromatinone-carbon metabolismeye healthophthalmologygene expressiontranscriptome

Abstract 17196: Genetic and Acquired Dhcr7 Deficiency Upregulates 7β-Hydroxycholesterol to Drive Endothelial Apoptosis and Pulmonary Hypertension. Circulation (2023)

Rashmi J RaoHee-Jung KimSiyi JiangYi-Yin TaiBing WangYing TangWadih El KhouryAnna KirillovaYassmin Al AarajAnnie WatsonAnkit X SharmaJeffrey McDonaldKevin FrancisSriganesh Ramachandra RaoSteven J FlieslerThomas BerteroWei SunLloyd D HarveyStephen Y Chan

cardiovascular researchvascular biologycardiologyclinical lipidologycirculatory physiologyliver physiologyendothelial apoptosisimmunologyendothelial dysfunctionmembrane biologypulmonary hypertensionpharmacologyrenal pathophysiologyhuman geneticsendocrinologygenetic epidemiologygenetics

A Dhdds K42E Knock-in Rp59 Mouse Model Shows Inner Retina Pathology and Defective Synaptic Transmission. Cell Death and Disease (2023)

Mai N. NguyenDibyendu ChakrabortySriganesh Ramachandra RaoAgnieszka OnyskMariusz RadkiewiczLiliana SurmaczEwa SwiezewskaEric SoubeyrandTariq A. AkhtarTimothy W. KraftDavid M. SherrySteven J. FlieslerSteven J. Pittler

cell deathretinaneuroscienceneurophysiologyophthalmologymammalian biologyinner retina pathologydefective synaptic transmissiongenetics

A Simple, Rapid Fluorescent Reporter-Based Method for Detection of Ectopic Cre Recombinase Expression in Presumed Retinal Cell Type-Targeted Mouse Lines. Experimental Eye Research (2023)

Sriganesh Ramachandra RaoSteven J. Fliesler

biological imagingoptogeneticsexperimental ophthalmologycell researchcell biologycell detectionvision researchbiomedical imagingfluorescence spectroscopyretinamammalian biologyexperimental medicineophthalmology retinareporter gene assayophthalmologygene expressionfluorescencegenetics

Cells Special Issue: “the Molecular and Cellular Basis of Retinal Diseases”. Cells (2023)

Steven J. PittlerSteven J. Fliesler

molecular and cellular biologyretinal diseasesretinacells special issuecell biologycellular physiologymolecular cell biologycellular biologymolecular basismolecular biologyophthalmologycellular basiscell and molecular biology

In Memoriam: G. Stephen (Steve) Tint, Phd (1935–2022). Journal of Lipid Research (2023)

Steven J. FlieslerRobert D. Steiner

lipidsvascular biologydermatologylipid sciencebiologymaterials science

Map4Ks Inhibition Promotes Retinal Neuron Regeneration From MüLler Glia in Adult Mice. npj Regenerative Medicine (2023)

Houjian ZhangYuli GuoYaqiong YangYuqian WangYouwen ZhangJingbin ZhuangYuting ZhangMei ShenJiankai ZhaoRongrong ZhangYan QiuShiying LiJiaoyue HuWei LiJianfeng WuHaiwei XuSteven J. FlieslerYi LiaoZuguo Liu

regenerative medicineretinal neuron regenerationmuller gliaretinaneuro-ophthalmologydevelopmental neurobiologycellular neurobiologyneuroscienceneurophysiologyophthalmologymammalian biologyadult micecentral nervous systemgeneticsneuroregeneration

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Steven Fliesler

SUNY Distinguished Professor; Meyer H Riwchun Endowed Chair Professor Vice-Chair and Director of Research Professor

University at Buffalo

Affiliations

Jacobs School of Medicine and Biomedical Sciences

Ophthalmology

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Steven Fliesler

University at Buffalo

SUNY Distinguished Professor; Meyer H Riwchun Endowed Chair Professor Vice-Chair and Director of Research Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bottlenecks in the Investigation of Retinal Sterol Homeostasis. Biomolecules (2024)

Sriganesh Ramachandra RaoSteven J. Fliesler

biophysicscardiovascular researchvascular biologyretinaretinal sterol homeostasismembrane biologymolecular biologyophthalmology

Inherited Retinal Degeneration Caused by Dehydrodolichyl Diphosphate Synthase Mutation–Effect of an Alg6 Modifier Variant. International Journal of Molecular Sciences (2024)

Elisha MonsonArtur V. CideciyanAlejandro J. RomanAlexander SumarokaMalgorzata SwiderVivian WuIryna ViarbitskayaSamuel G. JacobsonSteven J. FlieslerSteven J. Pittler

genetic engineeringhematologymolecular sciencegenetic variationallelic variantocular diseasemolecular biologyretinal degenerationhuman geneticsophthalmologygenetics

Steven J. Fliesler

Bruce A. PfefferSteven J. Fliesler

Abstract 17196: Genetic and Acquired Dhcr7 Deficiency Upregulates 7β-Hydroxycholesterol to Drive Endothelial Apoptosis and Pulmonary Hypertension. Circulation (2023)

A Dhdds K42E Knock-in Rp59 Mouse Model Shows Inner Retina Pathology and Defective Synaptic Transmission. Cell Death and Disease (2023)

cell deathretinaneuroscienceneurophysiologyophthalmologymammalian biologyinner retina pathologydefective synaptic transmissiongenetics

A Simple, Rapid Fluorescent Reporter-Based Method for Detection of Ectopic Cre Recombinase Expression in Presumed Retinal Cell Type-Targeted Mouse Lines. Experimental Eye Research (2023)

Sriganesh Ramachandra RaoSteven J. Fliesler

Cells Special Issue: “the Molecular and Cellular Basis of Retinal Diseases”. Cells (2023)

Steven J. PittlerSteven J. Fliesler

In Memoriam: G. Stephen (Steve) Tint, Phd (1935–2022). Journal of Lipid Research (2023)

Steven J. FlieslerRobert D. Steiner

lipidsvascular biologydermatologylipid sciencebiologymaterials science

Map4Ks Inhibition Promotes Retinal Neuron Regeneration From MüLler Glia in Adult Mice. npj Regenerative Medicine (2023)

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membrane protein transport

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