Faculty

Institution

Unit

Venue

Jun Song

Founder Professor in Physics

UIUC

Affiliations

The Grainger College of Engineering

Department of Physics

Physics

Jun Song is currently serving as a Physics Founder Professor in Physics at Uiuc.

Honors

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Experiences

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Education

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Jun Song

UIUC

Founder Professor in Physics

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cell biology genetics molecular cell biology genome biology systems biology molecular cancer gene expression oncogenes cancer cells epigenetics tumor biology bioinformatics transcription factors cancer genetics cancer genomics functional genomics chromatin genomics nucleic acids molecular informatics developmental biology biomedical informatics cancer discovery developmental cell brain tumor research cancer biology stem cell research chromatin remodeling molecular diagnostics epigenetic changes transcription regulation cell regulation epigenomics tumor suppressors cell research computational genomics single-cell analysis variant interpretation somatic variant genome structure genome-wide association studies tumor heterogeneity melanoma cellular physiology structural molecular biology high throughput sequencing nuclear organization dna analysis gene regulation sequence analysis dna methylation cancer susceptibility hormonal receptor small rna microrna detection neural stem cells embryonic stem cells gene regulatory networks gene expression profiling next-generation sequencing cell detection translational bioinformatics human genome histone modifications categorical spectral analysis clustering engine genome-wide analysis recurrent tumors brain tumor recurrent glioma mirna promoter nucleosome mapping incomplete dna methylation human ips cells transcriptional memory specific transcription factor

Notable Scholarly Works

Notable Federal Grants

Collaborators

The Immortality Mechanism of Tert Promoter Mutant Cancers is Self-Reinforcing and Reversible. Molecular Cell (2025)

Nicholas O SteversSomang KimJimmy Bo YuanCarter J BargerChibo HongOlivia LenzoAndrew M McKinneySamuel H WuYu Jin LeeDarwin W KwokAbigail K SuwalaChristina L AppinJohn D GordanAnnette M MolinaroJun S SongJoseph F Costello

oncogenesradiation oncologytumor biologyimmortality mechanismtranscription factorscell biologymolecular cancercarcinogenesismolecular cell biologycancer cellsgene expressioncancer geneticscancer genomics

Abstract 3020: The Tumor Suppressive Role of Methylthioadenosine Phosphorylase in Melanoma. Cancer Research (2024)

Jennifer J. HsiaoPedro Andreu-PerezLajos V. KeményMiroslav HejnaJérémie NsengimanaJennifer AlloucheAbdullah Al EmranD. Timothy BishopGöran B. JönssonJulia Newton-BishopJun SongDavid E. Fisher

pathologycarcinogenesismtap deficiencymta accumulationtumor biologyepigeneticscell biologymelanomamtap genecancer researchtumor suppressorscancer cellsgene expressiononcogenesmolecular cancercell metabolismcancer biologymolecular metabolismcancer genetics

CORRIGENDUM: Chromatin Structure and Context-Dependent Sequence Features Control Prime Editing Efficiency. Frontiers in Genetics (2024)

Somang KimJimmy B. YuanWendy S. WoodsDestry A. NewtonPablo Perez-PineraJun S. Song

gene editinggenome editingchromatin remodelingnucleic acidsepigeneticsfunctional genomicsgenome biologymolecular cell biologychromatin structuretranscription (biology)molecular biologychromatintranscription regulationgene expressioncontext-dependent sequence featuresgenetics

A Unified and Self-Reinforcing Mechanism of Tumor Cell Immortality. Research Square (Research Square) (2023)

Nicholas SteversCarter BargerJimmy YuanSomang KimChibo HongOlivia LenzoAndrew McKinneySamuel WuYu-Jin LeeDarwin KwokAbigail SuwalaChristina AppinJohn D. GordanAnnette MolinaroJun SongJoseph Costello

oncogenestumor biologytranscription factorscell biologycarcinogenesiscancer researchtelomerase reverse transcriptasesystems biologycancer cellsgene expressioncancer geneticsgabp dimerscancer biology

Ccrg-05. a Unifying and Self-Reinforcing Mechanism of Tumor Immortality in Tert Promoter Mutant Cancers. Neuro-Oncology (2023)

Nicholas SteversCarter BargerJimmy YuanSomang KimChibo HongOlivia LenzoAndrew McKinneySamuel WuYu-Jin LeeSara CollinsGeorgios BatsiosDarwin KwokAbigail SuwalaChristina AppinPavithra ViswanathNoriyuki KasaharaJohn GordanAnnette MolinaroJun SongJoseph Costello

oncogenesradiation oncologytumor biologydominant negative gabpb1transcription factorscell biologymolecular cancergabp tetramercancer researchmolecular cell biologycancer cellsgene expressioncancer geneticsgabp dimerscancer biology

Leveraging Epigenomes and Three-Dimensional Genome Organization for Interpreting Regulatory Variation. PLoS Computational Biology (2023)

Brittany BaurJunha ShinJacob SchreiberShilu ZhangYi ZhangMohith ManjunathJun S. SongWilliam Stafford NobleSushmita Roy

regulatory snpsregulatory variantsbiomedical informaticsgenomicsgenome biologygenome-wide association studiessystems biologyregulatory network modellingcomputational genomicsregulatory variationstatistical geneticsgenetics

Path-02. Novel Sox10 Indel Mutations Drive Schwannomas Through Impaired Transactivation of Myelination Gene Programs. Neuro-Oncology (2023)

Erik WilliamsAjay RavindranathanRohit GuptaNicholas SteversAbigail SuwalaChibo HongSomang KimJimmy YuanJasper WuJairo BarretoCalixto-Hope LucasEmily ChanMelike PekmezciPhilip LeboitThaddeus MullyArie PerryAndrew BollenJessica Van ZiffleW Patrick DevineAlyssa T ReddyNalin GuptaKristen BasnetRobert MacaulayPatrick MalafronteHan LeeWilliam YongKevin Jon WilliamsTareq JuratliDouglas MataRichard HuangMatthew HiemenzDean PavlickGarrett FramptonTyler JanovitzJeffrey RossSusan ChangMitchel BergerLine JacquesJun SongJoseph CostelloDavid Solomon

somatic variantpathologyneurogeneticssox10 genesox10 transcription factorcell biologymolecular cancerbrain tumor researchdisease gene identificationindel mutationsmolecular diagnosticscancer discoverycancer geneticsmolecular neurosciencecancer cellstumor innervationcancer genomicsneuro-oncology

Predicting the Molecular Functions of Regulatory Genetic Variants Associated With Cancer. Oncotarget (2023)

Jun S. SongMohith Manjunath

oncogenessomatic variantmolecular functionsregulatory genetic variantsmolecular cancervariant interpretationcarcinogenesiscancer discoverymolecular diagnosticssystems biologyhuman geneticscancer geneticsgenetics

Spectral Clustering of Single-Cell Multi-Omics Data on Multilayer Graphs. Bioinformatics (2022)

Shuyi ZhangJacob R LeisticoRaymond J ChoJeffrey B ChengJun S Song

biostatisticsgraph theorycomputational biologybiomedical data scienceclusteringbiomedical analysismultilayer graphssingle-cell analysismolecular informaticsdata sciencecell heterogeneitysystems biologyomicscell researchhamiltonian operatorsingle cell sequencingbioinformaticsmultiomics

Chd1 Protects Genome Integrity at Promoters to Sustain Hypertranscription in Embryonic Stem Cells. Nature Communications (2021)

Aydan Bulut-KarsliogluHu JinYun-Kyo KimBrandon ChoMarcela Guzman-AyalaAndrew J. K. WilliamsonMiroslav HejnaMaximilian StötzelAnthony D. WhettonJun S. SongMiguel Ramalho-Santos

stem cell researchstem cellsdevelopmental biologygeneticstranscription factorscell biologyepigeneticstranscription (biology)transcription regulationgene expressiondna repairgenome instabilitydevelopmental cellnucleic acidsgene regulationcell regulationchromatin remodelingmolecular cell biologychromatingenome integritychromatin remodeler chd1

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Jun Song

Founder Professor in Physics

UIUC

Affiliations

The Grainger College of Engineering

Department of Physics

Physics

Jun Song is currently serving as a Physics Founder Professor in Physics at Uiuc.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jun Song

UIUC

Founder Professor in Physics

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

The Immortality Mechanism of Tert Promoter Mutant Cancers is Self-Reinforcing and Reversible. Molecular Cell (2025)

Abstract 3020: The Tumor Suppressive Role of Methylthioadenosine Phosphorylase in Melanoma. Cancer Research (2024)

Jennifer J. HsiaoPedro Andreu-PerezLajos V. KeményMiroslav HejnaJérémie NsengimanaJennifer AlloucheAbdullah Al EmranD. Timothy BishopGöran B. JönssonJulia Newton-BishopJun SongDavid E. Fisher

CORRIGENDUM: Chromatin Structure and Context-Dependent Sequence Features Control Prime Editing Efficiency. Frontiers in Genetics (2024)

Somang KimJimmy B. YuanWendy S. WoodsDestry A. NewtonPablo Perez-PineraJun S. Song

A Unified and Self-Reinforcing Mechanism of Tumor Cell Immortality. Research Square (Research Square) (2023)

Nicholas SteversCarter BargerJimmy YuanSomang KimChibo HongOlivia LenzoAndrew McKinneySamuel WuYu-Jin LeeDarwin KwokAbigail SuwalaChristina AppinJohn D. GordanAnnette MolinaroJun SongJoseph Costello

oncogenestumor biologytranscription factorscell biologycarcinogenesiscancer researchtelomerase reverse transcriptasesystems biologycancer cellsgene expressioncancer geneticsgabp dimerscancer biology

Ccrg-05. a Unifying and Self-Reinforcing Mechanism of Tumor Immortality in Tert Promoter Mutant Cancers. Neuro-Oncology (2023)

Leveraging Epigenomes and Three-Dimensional Genome Organization for Interpreting Regulatory Variation. PLoS Computational Biology (2023)

Brittany BaurJunha ShinJacob SchreiberShilu ZhangYi ZhangMohith ManjunathJun S. SongWilliam Stafford NobleSushmita Roy

Path-02. Novel Sox10 Indel Mutations Drive Schwannomas Through Impaired Transactivation of Myelination Gene Programs. Neuro-Oncology (2023)

Predicting the Molecular Functions of Regulatory Genetic Variants Associated With Cancer. Oncotarget (2023)

Jun S. SongMohith Manjunath

Spectral Clustering of Single-Cell Multi-Omics Data on Multilayer Graphs. Bioinformatics (2022)

Shuyi ZhangJacob R LeisticoRaymond J ChoJeffrey B ChengJun S Song

Chd1 Protects Genome Integrity at Promoters to Sustain Hypertranscription in Embryonic Stem Cells. Nature Communications (2021)

Aydan Bulut-KarsliogluHu JinYun-Kyo KimBrandon ChoMarcela Guzman-AyalaAndrew J. K. WilliamsonMiroslav HejnaMaximilian StötzelAnthony D. WhettonJun S. SongMiguel Ramalho-Santos

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