Faculty

Institution

Unit

Venue

Satish K Nair

Head and Gregorio Weber Chair

UIUC

Affiliations

College of Liberal Arts & Sciences

Department of Biochemistry

School of Molecular & Cellular Biology

Department of Biochemistry

Satish K Nair is currently serving as a College Of Liberal Arts & Sciences Head and Gregorio Weber Chair at Uiuc.

Honors

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Experiences

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Education

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Satish K Nair

UIUC

Head and Gregorio Weber Chair

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biochemistry enzymes molecular biology structural molecular biology biosynthesis biological chemistry biomolecular structure protein structure biomolecules structural biology chemical biology biomolecular engineering enzyme inhibition microbiology structure-function enzyme kinetics peptides protein science enzyme catalysis peptide synthesis natural product biosynthesis biocatalysis protein biosynthesis peptide science biochemical sciences molecular metabolism antimicrobial agents biological macromolecules crystal structures biophysical chemistry protein synthesis antibiotics molecular microbiology protein x-ray crystallography biotechnology biotransformation nucleic acids enzymatic modification active site applied microbiology molecular structure natural product synthesis microbial cell factory bacteriology protein chemistry modified peptides polysaccharides peptide engineering antimicrobial compounds carbohydrate-protein interactions protein assembly metalloproteins peptide library conformational studies protein function bioconjugation cellular enzymology altmetric attention score antibacterial agents enzyme specificity carbonic anhydrase ii escherichia coli dna analysis antibiotic resistance biomolecular interactions hemicelluloses cocrystal structure hydrophobic pocket ribosomal peptide biosynthesis leader peptide structural basis peptide substrate cyclic peptides linear peptides peptide natural products cyclization process xylan utilization infectious diseases microbial pathogenesis clinical microbiology drug discovery

Notable Scholarly Works

Notable Federal Grants

Collaborators

Combatting Virulent Gut Bacteria by Inhibiting the Biosynthesis of a Two-Component Lanthipeptide Toxin. Nature Communications (2025)

Ryan MoreiraBidisha ChakrabortyYi YangChandrashekhar PadhiMichael S GilmoreSatish K NairWilfred A van der Donk

antimicrobial agentsenzyme inhibitionmicrobial pathogenesispeptidesmicrobial toxinstoxinscrystal structuresdrug discoveryblock cytolysin maturationpeptide therapeuticsmicrobiologybiochemistrytoxin maturation

Genetic and Biochemical Characterization of a Radical Sam Enzyme Required for Post-Translational Glutamine Methylation of Methyl-Coenzyme M Reductase. mBio (2025)

Roy J. Rodriguez CarreroCody T. LloydJanhavi BorkarShounak NathLiviu M. MiricaSatish NairSquire J. BookerWilliam Metcalf

mcra peptidestructure-function enzyme kineticsbiomolecular engineeringenzymesbiocatalysisradical sam enzymebiological chemistryenzyme catalysisactive sitemetabolismbiochemical sciencesbiochemistry

Bacillus Subtilis Utilizes Decarboxylated S -Adenosylmethionine for the Biosynthesis of Tandem Aminopropylated Microcin C, a Potent Inhibitor of Bacterial Aspartyl-Trna Synthetase. Journal of the American Chemical Society (2025)

Alexey KulikovskyEldar YagmurovAnastasiia GrigorevaAleksandr PopovKonstantin SeverinovSatish K. NairGuy LippensMarina SerebryakovaSergei BorukhovSvetlana Dubiley

microbial cell factorynatural product synthesispeptide synthesisbiochemistrypolyamine biosynthesischemical biologyenzymesantibioticsbiomoleculesmetabolic engineeringbacillus subtilis mg27biochemical sciencesbiosynthesisantimicrobial agentsbsu-mcc biosynthesisprotein synthesisbiocatalysisenzyme inhibitionmicrobiologynatural product biosynthesis

The Redox Landscape of Pyruvate: Ferredoxin Oxidoreductases Reveals Often Conserved Fe–S Cluster Potentials. Journal of Biological Chemistry (2025)

Sheila C BonitatibusRyan V PhamAndrew C WeitzMadeline M Lopéz-MuñozBin LiWilliam W MetcalfSatish K NairSean J Elliott

microbial physiologystructure-function enzyme kineticsredox biologypfor enzymesredox chemistryenzymesmolecular metabolismmolecular biologyenzyme catalysisma pforredox landscapemetabolismbioenergeticsbiochemistry

Yerba Mate (Ilex Paraguariensis) Genome Provides New Insights Into Convergent Evolution of Caffeine Biosynthesis. eLife (2025)

Federico A VignaleAndrea Hernandez GarciaCarlos P ModenuttiEzequiel J SosaLucas A DefelipeRenato OliveiraGisele L NunesRaúl M AcevedoGerman F BurguenerSebastian M RossiPedro D ZapataDardo A MartiPedro SansberroGuilherme OliveiraEmily M CataniaMadeline N SmithNicole M DubsSatish NairTodd J BarkmanAdrian G Turjanski

genomicsgenome biologyprotein evolutiongenome structuregeneticsyerba matemolecular biologystructural molecular biologymolecular evolutioncaffeine biosynthesisbiomolecular structurecrystal structuresbiosynthesis

Biosynthesis of Peptide–Nucleobase Hybrids in Ribosomal Peptides. Nature Chemical Biology (2024)

Zeng-Fei PeiNatalia M ViorLingyang ZhuAndrew W TrumanSatish K Nair

biosynthesispeptidespeptide scienceenzymesprotein synthesismolecular biologybiological chemistryribosomal peptidesbiomoleculesprotein biosynthesispeptide synthesisnucleic acids

Epistasis Mediates the Evolution of the Receptor Binding Mode in Recent Human H3N2 Hemagglutinin. Nature Communications (2024)

Ruipeng LeiWeiwen LiangWenhao O. OuyangAndrea Hernandez GarciaChika KikuchiShengyang WangRyan McBrideTimothy J. C. TanYuanxin SunChunke ChenClaire S. GrahamLucia A. RodriguezIvana R. ShenDanbi ChoiRoberto BruzzoneJames C. PaulsonSatish K. NairChris K. P. MokNicholas C. Wu

immunologyvirus researchreceptorsreceptor-binding sitevirus structuregeneral virologyprotein structureviral geneticsvirologyviral evolutionmolecular biologystructural molecular biologyrecent evolutioninfluenzahemagglutinin receptor-binding sitestructural biologyviral structural proteinprotein science

Structural Organization of Pyruvate: Ferredoxin Oxidoreductase From the Methanogenic Archaeon Methanosarcina Acetivorans. Structure (2024)

Matteo CossuDaniel CatlinSean J ElliottWilliam W MetcalfSatish K Nair

structural organizationstructure-function enzyme kineticsredox biologyferredoxin oxidoreductasechemical biologyenzymesmolecular metabolismbiocatalysismolecular biologybiological chemistryenzyme catalysisbiochemistry

Tail-Tape-Fused Virion and Non-Virion Rna Polymerases of a Thermophilic Virus With an Extremely Long Tail. Nature Communications (2024)

Anastasiia ChabanLeonid MinakhinEkaterina GoldobinaBrain BaeYue HaoSergei BorukhovLeena PutzeysMaarten BoonFlorian KabingerRob LavigneKira S. MakarovaEugene V. KooninSatish K. NairShunsuke TagamiKonstantin SeverinovMaria L. Sokolova

virus researchp23-45 tmpvirus structuretranscription (biology)general virologybiologybiomolecular structureviral geneticsvirologymiddle phage genesmolecular biologystructural molecular biologymolecular evolutionstructural biologyviral replicationancestral phagemicrobiologynucleic acids

The Redox Landscape of the 2-Oxoacid: Ferredoxin Oxidoreductase Superfamily Reveals Universally Conserved Fe–S Cluster Potentials. SSRN Electronic Journal (2024)

Sheila BonitatibusAndrew WeitzMadeline M. Lopez-MuñozBin LiMatteo CossuWilliam MetcalfSatish K. NairSean Elliott

biophysical chemistryredox signalingfree radical biologyredox biologyredox chemistrychemical biologyenzymesmolecular biologybiological chemistrystructural molecular biologyredox landscapetransition metal chemistryoxidative stressbiochemistry

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Satish K Nair

Head and Gregorio Weber Chair

UIUC

Affiliations

College of Liberal Arts & Sciences

Department of Biochemistry

School of Molecular & Cellular Biology

Department of Biochemistry

Satish K Nair is currently serving as a College Of Liberal Arts & Sciences Head and Gregorio Weber Chair at Uiuc.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Satish K Nair

UIUC

Head and Gregorio Weber Chair

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Combatting Virulent Gut Bacteria by Inhibiting the Biosynthesis of a Two-Component Lanthipeptide Toxin. Nature Communications (2025)

Ryan MoreiraBidisha ChakrabortyYi YangChandrashekhar PadhiMichael S GilmoreSatish K NairWilfred A van der Donk

Genetic and Biochemical Characterization of a Radical Sam Enzyme Required for Post-Translational Glutamine Methylation of Methyl-Coenzyme M Reductase. mBio (2025)

Roy J. Rodriguez CarreroCody T. LloydJanhavi BorkarShounak NathLiviu M. MiricaSatish NairSquire J. BookerWilliam Metcalf

mcra peptidestructure-function enzyme kineticsbiomolecular engineeringenzymesbiocatalysisradical sam enzymebiological chemistryenzyme catalysisactive sitemetabolismbiochemical sciencesbiochemistry

Alexey KulikovskyEldar YagmurovAnastasiia GrigorevaAleksandr PopovKonstantin SeverinovSatish K. NairGuy LippensMarina SerebryakovaSergei BorukhovSvetlana Dubiley

The Redox Landscape of Pyruvate: Ferredoxin Oxidoreductases Reveals Often Conserved Fe–S Cluster Potentials. Journal of Biological Chemistry (2025)

Sheila C BonitatibusRyan V PhamAndrew C WeitzMadeline M Lopéz-MuñozBin LiWilliam W MetcalfSatish K NairSean J Elliott

Yerba Mate (Ilex Paraguariensis) Genome Provides New Insights Into Convergent Evolution of Caffeine Biosynthesis. eLife (2025)

Biosynthesis of Peptide–Nucleobase Hybrids in Ribosomal Peptides. Nature Chemical Biology (2024)

Zeng-Fei PeiNatalia M ViorLingyang ZhuAndrew W TrumanSatish K Nair

biosynthesispeptidespeptide scienceenzymesprotein synthesismolecular biologybiological chemistryribosomal peptidesbiomoleculesprotein biosynthesispeptide synthesisnucleic acids

Epistasis Mediates the Evolution of the Receptor Binding Mode in Recent Human H3N2 Hemagglutinin. Nature Communications (2024)

Structural Organization of Pyruvate: Ferredoxin Oxidoreductase From the Methanogenic Archaeon Methanosarcina Acetivorans. Structure (2024)

Matteo CossuDaniel CatlinSean J ElliottWilliam W MetcalfSatish K Nair

Tail-Tape-Fused Virion and Non-Virion Rna Polymerases of a Thermophilic Virus With an Extremely Long Tail. Nature Communications (2024)

The Redox Landscape of the 2-Oxoacid: Ferredoxin Oxidoreductase Superfamily Reveals Universally Conserved Fe–S Cluster Potentials. SSRN Electronic Journal (2024)

Sheila BonitatibusAndrew WeitzMadeline M. Lopez-MuñozBin LiMatteo CossuWilliam MetcalfSatish K. NairSean Elliott

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5
19
10 / page