Faculty

Institution

Unit

Venue

Simone Krebs

The University of Texas MD Anderson Cancer Center

Affiliations

Center For Nuclear Receptors And Cell Signaling

Department Of Imaging Physics

Institute for Data Science in Oncology

Simone Krebs is a Senior Professor at The University of Texas MD Anderson Cancer Center. Her research integrates oncology, nuclear medicine, and neuro-oncology, focusing on advanced cancer imaging and radiotheranostics. Her recent work includes investigating lesion absorbed dose–response relationships in [177Lu]Lu-PSMA-617 therapy for metastatic castration-resistant prostate cancer, developing IL13Rα2-targeting antibodies for immuno-PET in solid malignancies, and exploring CAR T cell-derived exosomes for radiotheranostic applications. She also investigates tumor microenvironment modulation via epithelial-mesenchymal transition and contributes to multidisciplinary frameworks combining immunotherapy with radiotherapy, as highlighted in her 2025 Lancet Oncology proceedings.

Honors

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Experiences

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Education

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Simone Krebs

The University of Texas MD Anderson Cancer Center

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oncology radiation oncology nuclear medicine cancer imaging medical imaging medicine radiology brain tumor research neuro-oncology pharmacology cancer research cancer immunotherapy immunotherapy radiopharmaceutical therapy cellular therapy positron emission tomography molecular imaging medicinal research cancer treatment theranostics endocrine oncology radiation therapy therapeutic targets biomedical imaging cancer biology tumor targeting ct scan pet-mri oncologic imaging oncogenes cancer care computed tomography neuroendocrine disorders cancer discovery digestive diseases molecular diagnostics photomedicine dosimetry magnetic resonance imaging endocrine-related cancers clinical radiation oncology artemisia absinthium peptide science phytotherapy research histopathology nuclear science nuclear safety translational imaging inflammatory diseases mucosal immunology metastatic neuroendocrine tumors oncologic population clinical efficacy radioimmunotherapy applications well-differentiated neuroendocrine tumors pilot experiment tumor heterogeneity cancer growth anti-inflammatory ulcerative colitis synthetic immunology antibody engineering antibody screening lymphocyte development pharmacokinetics lymphoid neoplasia pilot study somatostatin receptor agonist epithelial-mesenchymal transition targeted cancer therapies crohn ’ double-blind placebo-controlled study steroid-sparing effect radiation dose estimates concomitant liver fat liver iron

Notable Scholarly Works

Notable Federal Grants

Collaborators

Case Report: Management of a Challenging Case Presenting With Dysphagia After Thyroidectomy Requiring Administration of Liquid 131I via Mic-Key Low-Profile Tube—a Multidisciplinary Approach. Frontiers in Medicine (2026)

surgerymedicinethyroidchallenging casecase reportliquid 131ithyroid disease

255 Noninvasive Tracking of Il13Rα2 Car-T Cells With Immunopet Reveals Spatiotemporal Dynamics and Persistence in a Melanoma Model. Regular and Young Investigator Award Abstracts (2025)

immunologymelanomacellular immune responsescancer immunotherapymelanoma modelnoninvasive trackingil13rα2 car-t cellsimmune responsescancer cellsimmunomodulationcellular therapyimmunotherapycell biology

Abstract 585: Utilizing Car T Cell-Derived Exosomes for Radiotheranostic Applications. Cancer Research (2025)

biophysicscell engineeringnanomedicineabstract 585cell researchcellular therapybiomolecular engineeringdrug deliveryextracellular microvesicles

Differential Clearance of [ 177 Lu]Lu-Psma-617 From Metastatic Prostate Cancer Lesions and Normal Tissues Creates a Window for Safe Application of Dna Repair Inhibitors. medRxiv (2025)

metastasisdna repairnormal tissuestheranosticsprostate cancercell biologymolecular cancerurologyradiopharmaceutical therapytherapeutic targetsdifferential clearanceradiation oncologydna repair inhibitorsprostatic diseasegenitourinary cancerscancer imagingoncologyoncogenescancer cells

Genioglossus Muscle Uptake on 18F-Fdg Pet/Ct, Secondary to Hypoglossal Nerve Stimulation. Clinical Nuclear Medicine (2025)

physiologyneurologygenioglossus muscle uptakemuscle function18f-fdg pet/ctperipheral nerveanatomyspinal cordhypoglossal nerve stimulationneuroscienceneurophysiology

Harnessing the Tumor Microenvironment: Targeted Cancer Therapies Through Modulation of Epithelial-Mesenchymal Transition. Journal of Hematology & Oncology (2025)

Antonino GlavianoHannah Si-Hui LauLukas M. CarterE. Hui Clarissa LeeHiu Yan LamElena OkinaDonavan Jia Jie TanWency TanHui Li AngDaniela CarboneMichelle Yi-Hui YeeMuthu K. ShanmugamXiao Zi HuangGautam SethiTuan Zea TanLina H. K. LimRuby Yun-Ju HuangHendrik UngefrorenElisa GiovannettiDean G. TangTullia C. BrunoPeng LuoMads Hald AndersenBin-Zhi QianJun IshiharaDerek C. RadiskySalem EliasSaurabh YadavMinah KimCaroline RobertPatrizia DianaKurt A. SchalperTao ShiTaha MerghoubSimone KrebsAnjali P. KusumbeMatthew S. DavidsJennifer R. BrownAlan Prem Kumar

tumor heterogeneitycell biologytumor targetingepithelial-mesenchymal transitionvascular biologymatrix biologytumor microenvironmenttargeted cancer therapiescancer biologycancer researchcancer immunotherapycancer growthcancer treatmenttumor biologybiomedical engineeringradiation oncologycancer discoveryoncologyoncogenescancer cells

Il13Rα2-Targeting Antibodies for Immuno-Pet in Solid Malignancies. Journal of Nuclear Medicine (2025)

Leah GajeckiIrina V LebedevaYu-Rou LiaoDaisy AmbrizLukas M CarterMelina KumpfSamantha LovibondJustin S HacheyMaya S GrahamMichael PostowJason S LewisDavid P AndrewManuel BacaHeiko SchöderSteven M LarsonDarren R VeachSimone Krebs

immunologysolid malignanciesclinical immunologycancer immunotherapynuclear medicine

Immunotheranostics in Solid Tumors: Longitudinal Tracking of Human Il13Rα2 Car-T Cells in Vivo. Journal of Nuclear Medicine (2025)

immunologysolid tumorscellular immune responseslongitudinal trackingcell researchcancer immunotherapyimmune responsescancer cellsimmunomodulationpathologycellular therapyimmunotherapy

Investigating Metabolic Connectivity in Patients With Multiple Myeloma Receiving Bcma Car T Cell Therapy.. Journal of Clinical Oncology (2025)

immunologyhematological malignanciesmedicinemyeloid neoplasiahematologycancer immunotherapyoncologycell transplantationtumor microenvironmentmultiple myelomacellular therapyhealth sciencesimmunotherapymetabolic connectivity

Lesion Absorbed Dose–Response Relationship in Patients With Metastatic Castration-Resistant Prostate Cancer Undergoing [ 177 Lu]Lu-Psma-617 Radiopharmaceutical Therapy. Journal of Nuclear Medicine (2025)

medicinemetastasiscancer careradiation oncologyurologypharmacotherapyprostatic diseasegenitourinary cancerscancer imagingoncologynuclear medicineradiation therapyradiationprostate cancer

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Simone Krebs

The University of Texas MD Anderson Cancer Center

Affiliations

Center For Nuclear Receptors And Cell Signaling

Department Of Imaging Physics

Institute for Data Science in Oncology

Honors

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Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Simone Krebs

The University of Texas MD Anderson Cancer Center

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

surgerymedicinethyroidchallenging casecase reportliquid 131ithyroid disease

255 Noninvasive Tracking of Il13Rα2 Car-T Cells With Immunopet Reveals Spatiotemporal Dynamics and Persistence in a Melanoma Model. Regular and Young Investigator Award Abstracts (2025)

Abstract 585: Utilizing Car T Cell-Derived Exosomes for Radiotheranostic Applications. Cancer Research (2025)

biophysicscell engineeringnanomedicineabstract 585cell researchcellular therapybiomolecular engineeringdrug deliveryextracellular microvesicles

Differential Clearance of [ 177 Lu]Lu-Psma-617 From Metastatic Prostate Cancer Lesions and Normal Tissues Creates a Window for Safe Application of Dna Repair Inhibitors. medRxiv (2025)

Genioglossus Muscle Uptake on 18F-Fdg Pet/Ct, Secondary to Hypoglossal Nerve Stimulation. Clinical Nuclear Medicine (2025)

physiologyneurologygenioglossus muscle uptakemuscle function18f-fdg pet/ctperipheral nerveanatomyspinal cordhypoglossal nerve stimulationneuroscienceneurophysiology

Harnessing the Tumor Microenvironment: Targeted Cancer Therapies Through Modulation of Epithelial-Mesenchymal Transition. Journal of Hematology & Oncology (2025)

Il13Rα2-Targeting Antibodies for Immuno-Pet in Solid Malignancies. Journal of Nuclear Medicine (2025)

immunologysolid malignanciesclinical immunologycancer immunotherapynuclear medicine

Immunotheranostics in Solid Tumors: Longitudinal Tracking of Human Il13Rα2 Car-T Cells in Vivo. Journal of Nuclear Medicine (2025)

immunologysolid tumorscellular immune responseslongitudinal trackingcell researchcancer immunotherapyimmune responsescancer cellsimmunomodulationpathologycellular therapyimmunotherapy

Investigating Metabolic Connectivity in Patients With Multiple Myeloma Receiving Bcma Car T Cell Therapy.. Journal of Clinical Oncology (2025)

medicinemetastasiscancer careradiation oncologyurologypharmacotherapyprostatic diseasegenitourinary cancerscancer imagingoncologynuclear medicineradiation therapyradiationprostate cancer

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