Faculty

Institution

Unit

Venue

Sidney Strickland

Zachary and Elizabeth M Fisher Professor in Alzheimer’s and Neurodegenerative Disease

Rockefeller University

Affiliations

Heads of Laboratories

Sidney Strickland is currently serving as a Heads Of Laboratories Zachary and Elizabeth M Fisher Professor in Alzheimer’s and Neurodegenerative Disease at Rockefeller University.

Honors

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Experiences

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Education

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Sidney Strickland

Rockefeller University

Zachary and Elizabeth M Fisher Professor in Alzheimer’s and Neurodegenerative Disease

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neuroscience neurology molecular biology vascular biology cell biology alzheimer's disease neurodegenerative diseases neuroinflammation inflammation gene expression central nervous system stem cell research tissue plasminogen activator cellular differentiation membrane biology medicinal research molecular neurodegeneration cognitive impairment cerebral blood flow mammalian biology reproductive biology thrombosis neuroscience of aging vascular cognitive disorder bone research brain science fibrinolysis neurovascular diseases neuropsychopharmacology molecular cell biology hemostasis oocytes cell transplantation enzyme inhibition cell death cellular neurobiology vascular dementia peptides peripheral nervous system embryonic development inhibitory activity mouse model cell proliferation cellular biology cell migration cerebrovascular disease novel therapies key site rna processing developmental genetics protein expression brain function clinical neuroscience tissue development host factors cell motility neural science gene regulation peripheral nerve neuroregeneration experimental neuropathology cell regulation teratocarcinoma stem cells retinoic acid neuronal death plasminogen activator neuronal degeneration plasminogen activator production parietal endoderm early embryogenesis hormonal regulation mouse hippocampus schwann cell differentiation sciatic nerve injury coagulation factor xii cytoplasmic polyadenylation brain pathology neurovascular dysfunction blood flow

Notable Scholarly Works

Notable Federal Grants

Collaborators

Contactless Edema via Plasmin. Blood (2024)

Sidney StricklandErin H. Norris

immunologycontactless edemablood transfusionhematology

Lecanemab Blocks the Effects of the Aβ/Fibrinogen Complex on Blood Clots and Synapse Toxicity in Organotypic Culture. Proceedings of the National Academy of Sciences (2024)

Pradeep Kumar SinghElisa Nicoloso Simões-PiresZu-Lin ChenDaniel TorrenteMarissa CalvanoAnurag SharmaSidney StricklandErin H. Norris

organotypic cultureblood clotssynapse toxicitybiochemistry

A Possible Mechanism for the Enhanced Toxicity of Beta-Amyloid Protofibrils in Alzheimer’s Disease. Proceedings of the National Academy of Sciences (2023)

Zu-Lin ChenPradeep K. SinghMarissa CalvanoErin H. NorrisSidney Strickland

beta-amyloid protofibrilstoxicologyalzheimer's diseaseenhanced toxicityneurodegenerative diseasesbiochemistry

Fiberoptic Hemodynamic Spectroscopy Reveals Abnormal Cerebrovascular Reactivity in a Freely Moving Mouse Model of Alzheimer’s Disease. Frontiers in Molecular Neuroscience (2023)

Daniel S. GareauNicholas RochaKimArnab ChoudhuryMichael BamkoleMatija SnuderlJulia ZouAnna YaroslavskySteven L. JacquesSidney StricklandJames G. KruegerHyung Jin Ahn

brain scienceneurologymouse modelbiophysicscomputational neurosciencemolecular neurosciencemolecular neurobiologysystems neurosciencealzheimer's diseaseneuroscience

Striatal Fibrinogen Extravasation and Vascular Degeneration Correlate With Motor Dysfunction in an Aging Mouse Model of Alzheimer’s Disease. Frontiers in Aging Neuroscience (2023)

Hanna E. Berk-RauchArnab ChoudhuryAllison T. RichardsPradeep K. SinghZu-Lin ChenErin H. NorrisSidney StricklandHyung Jin Ahn

striatal fibrinogen extravasationaging-associated diseasesaging mouse modelmotor dysfunctionvascular degeneration correlatealzheimer's diseaseneuroscienceneurodegenerative diseases

Anti-Hk Antibody Inhibits the Plasma Contact System by Blocking Prekallikrein and Factor XI Activation in Vivo. Blood Advances (2022)

Zu-Lin ChenPradeep K. SinghKatharina HornMarissa R. CalvanoShigeru KanekiKeith R. McCraeSidney StricklandErin H. Norris

general virologyinhibitory activityantibody screeningtherapeutic efficacyfactor xi activationhematologyvascular biologyplasma contact systemtherapeutic targetsanti-hk antibodyantigen processingimmunity (medicine)immunotherapyhemostasisimmunologyenzyme inhibitionpharmacologybiomedical engineeringpharmacotherapyoncologymedicinal research

Anti-Hk Antibody Reveals Critical Roles of a 20-Residue Hk Region for Aβ-Induced Plasma Contact System Activation. Blood Advances (2022)

Zu-Lin ChenPradeep Kumar SinghKatharina HornSidney StricklandErin H. Norris

immunologyreceptorsbiomedical engineeringhematologythrombosisvascular biologyinnate immune systemtherapeutic targetsblood purificationadaptive immune systemmolecular immunologyantibody engineeringimmune responsesmedicinal researchantibody screeningcellular therapyimmunotherapycell biology

Contact and Intrinsic Coagulation Pathways Are Activated and Associated With Adverse Clinical Outcomes in Covid-19. Blood Advances (2022)

Michael W. HendersonFranciele LimaCarla Roberta Peachazepi MoraesAnton IlichStephany Cares HuberMayck Silva BarbosaIrene SantosAndre C. PalmaThyago Alves NunesRaisa Gusso UlafLuciana Costa RibeiroAna Flavia BernardesBruna BombassaroSergio San Juan DertkigilMaria Luiza MorettiSidney StricklandJoyce M. Annichino-BizzacchiFernanda Andrade OrsiEli MansourLicio A. VellosoNigel S. KeyErich Vinicius De Paula

pathogenesisclinical microbiologyviral pathogenesisinfectious diseasescohort studiespublic healthlong covidsars-cov-2thrombosisvascular biologyintrinsic coagulation pathwayscovid-19adverse clinical outcomesimmunologypathogensvirus researchdisease transmissioncovid-19 pandemicvirologyrespiratory medicine

Factor XII Plays a Pathogenic Role in Organ Failure and Death in Baboons Challenged With Staphylococcus Aureus. Blood (2021)

Robert SilasiRavi S. KeshariGirija RegmiCristina LupuConstantin GeorgescuJoe H. SimmonsMichael WallischTia C. L. KohsJoseph J. ShatzelSven R. OlsonChristina U. LorentzCristina PuyErik I. TuckerDavid GailaniSidney StricklandAndrás GruberOwen J. T. McCartyFlorea Lupu

pathogensdermatologycell deathmicrobial pathogenesispathogenesishematologyclinical microbiologyorgan failuregeneticsdeath studieshost factorspathogenic rolepathologyhost responsemortality

Fiberoptic Hemodynamic Spectroscopy: Validation in Glioma Model and Magnetic Probe to Study Cerebrovascular Dysregulation in Freely-Moving Alzheimer’s Disease Model Mice. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Daniel S. GareauMichael BamkoleMatija SnuderlCheddhi ThomasN. Sumru BayinDimitris G. PlacantonakisJulia ZouAnna YaroslavskyMichael P. DietzSteven L. JacquesSidney StricklandJames G. KruegerHyung Jin Ahn

neurologymagnetic probebiophysicsglioma modelfiberoptic hemodynamic spectroscopycerebrovascular dysregulationmammalian biologyfreely-moving alzheimeralzheimer's diseaseneuroscienceneuroanatomy

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Sidney Strickland

Zachary and Elizabeth M Fisher Professor in Alzheimer’s and Neurodegenerative Disease

Rockefeller University

Affiliations

Heads of Laboratories

Sidney Strickland is currently serving as a Heads Of Laboratories Zachary and Elizabeth M Fisher Professor in Alzheimer’s and Neurodegenerative Disease at Rockefeller University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Sidney Strickland

Rockefeller University

Zachary and Elizabeth M Fisher Professor in Alzheimer’s and Neurodegenerative Disease

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Contactless Edema via Plasmin. Blood (2024)

Sidney StricklandErin H. Norris

immunologycontactless edemablood transfusionhematology

Lecanemab Blocks the Effects of the Aβ/Fibrinogen Complex on Blood Clots and Synapse Toxicity in Organotypic Culture. Proceedings of the National Academy of Sciences (2024)

Pradeep Kumar SinghElisa Nicoloso Simões-PiresZu-Lin ChenDaniel TorrenteMarissa CalvanoAnurag SharmaSidney StricklandErin H. Norris

organotypic cultureblood clotssynapse toxicitybiochemistry

A Possible Mechanism for the Enhanced Toxicity of Beta-Amyloid Protofibrils in Alzheimer’s Disease. Proceedings of the National Academy of Sciences (2023)

Zu-Lin ChenPradeep K. SinghMarissa CalvanoErin H. NorrisSidney Strickland

beta-amyloid protofibrilstoxicologyalzheimer's diseaseenhanced toxicityneurodegenerative diseasesbiochemistry

Fiberoptic Hemodynamic Spectroscopy Reveals Abnormal Cerebrovascular Reactivity in a Freely Moving Mouse Model of Alzheimer’s Disease. Frontiers in Molecular Neuroscience (2023)

Daniel S. GareauNicholas RochaKimArnab ChoudhuryMichael BamkoleMatija SnuderlJulia ZouAnna YaroslavskySteven L. JacquesSidney StricklandJames G. KruegerHyung Jin Ahn

brain scienceneurologymouse modelbiophysicscomputational neurosciencemolecular neurosciencemolecular neurobiologysystems neurosciencealzheimer's diseaseneuroscience

Striatal Fibrinogen Extravasation and Vascular Degeneration Correlate With Motor Dysfunction in an Aging Mouse Model of Alzheimer’s Disease. Frontiers in Aging Neuroscience (2023)

Hanna E. Berk-RauchArnab ChoudhuryAllison T. RichardsPradeep K. SinghZu-Lin ChenErin H. NorrisSidney StricklandHyung Jin Ahn

striatal fibrinogen extravasationaging-associated diseasesaging mouse modelmotor dysfunctionvascular degeneration correlatealzheimer's diseaseneuroscienceneurodegenerative diseases

Anti-Hk Antibody Inhibits the Plasma Contact System by Blocking Prekallikrein and Factor XI Activation in Vivo. Blood Advances (2022)

Zu-Lin ChenPradeep K. SinghKatharina HornMarissa R. CalvanoShigeru KanekiKeith R. McCraeSidney StricklandErin H. Norris

Anti-Hk Antibody Reveals Critical Roles of a 20-Residue Hk Region for Aβ-Induced Plasma Contact System Activation. Blood Advances (2022)

Zu-Lin ChenPradeep Kumar SinghKatharina HornSidney StricklandErin H. Norris

Contact and Intrinsic Coagulation Pathways Are Activated and Associated With Adverse Clinical Outcomes in Covid-19. Blood Advances (2022)

Factor XII Plays a Pathogenic Role in Organ Failure and Death in Baboons Challenged With Staphylococcus Aureus. Blood (2021)

pathogensdermatologycell deathmicrobial pathogenesispathogenesishematologyclinical microbiologyorgan failuregeneticsdeath studieshost factorspathogenic rolepathologyhost responsemortality

neurologymagnetic probebiophysicsglioma modelfiberoptic hemodynamic spectroscopycerebrovascular dysregulationmammalian biologyfreely-moving alzheimeralzheimer's diseaseneuroscienceneuroanatomy

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Medical University of South Carolina

cell death

brain-immune interaction

Anna Csiszar

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University of Oklahoma Health Sciences Center

vascular aging

pulmonary vascular diseases

Raymond Swanson

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University of California, San Francisco

free radical biology

neuroprotection

Kunlin Jin

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University of North Texas Health Science Center

young adult

wounds and injuries

Gabriel G. Haddad

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respiratory medicine

pediatric pulmonology

Louis F. Reichardt

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cell biology

David Rowitch

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neurological progress

developmental neurobiology

J. Simard

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University of Maryland, Baltimore

neurovascular disease

acute cns diseases

David Spray

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neuroscience

cell biology

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degenerative pathology

neurodevelopmental disorder