Sharon Cheryll Francis

Morehouse School of Medicine

Affiliations

Department Of Cardiovascular Disease

Department Of Cardiovascular Medicine

Division Of Cardiovascular Medicine

MSM External Event Request Form

Morehouse School of Medicine

Physiology

NoneSharon Cheryll Francis is currently serving as a Cardiovascular Disease faculty at Morehouse School of Medicine.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Sharon Cheryll Francis

Morehouse School of Medicine

You can click a keyword to filter the displayed items

physiology cell metabolism cell signaling vascular biology molecular physiology cellular physiology metabolic regulation mitochondrial function pharmacology obesity obesity medicine metabolic remodeling metabolic syndrome hypertension health sciences medicine gene therapy cardiovascular research molecular cell biology mitochondrial dynamics cardiology diabetes research endothelial dysfunction energy homeostasis energy metabolism genomics mechanobiology cellular networks cell research clinical nutrition respiratory medicine medicinal research molecular science pediatric obesity public health nutrition antihypertensive therapy blood pressure glucocorticoids neovascularization cellular regulatory mechanism cell regulation intercellular communication nutrient physiology clinical immunology adaptive immune system human nutrition medical nutrition vascular pharmacology cardiovascular translational research human polymorphisms obesity management metabolic complications signaling pathways angiogenesis vascular adaptation photoreceptor cells metabolic disorders insulin signaling elevated blood pressure glucose intolerance insulin-resistant model hypertension therapy antisense gene therapy renin-angiotensin system cardiovascular therapeutics b-catenin dynamics brain g-adducin hypertension-linked decrease acute inflammatory conditions activated b-lymphocytes diet‐induced obesity mitochondrial connexins gap junction structure us research program

Notable Scholarly Works

Notable Federal Grants

Collaborators

1713-P: Deletion of Sgk1 in Smooth Muscle Cells Induces Adipose Tissue Beiging and Differential Secretion of Vasokines. Diabetes (2025)

physiologysignaling pathwayscellular physiologydifferential secretionmetabolic regulationcell signalingcell metabolismsignal transductioncellular differentiationtissue (biology)molecular physiologycell biology

Bmal1 Deletion Alters Mitochondrial Microstructure and Function in Mouse Cone Photoreceptors. iScience (2025)

photoreceptor cellscellular physiologycell signalingmitochondrial functionmolecular neurosciencemolecular and cellular biologymouse cone photoreceptorsmolecular cell biologymolecular biologycell metabolismmolecular physiologycellular biochemistrycell biology

Association Between Mcu Gene Polymorphisms With Obesity: Findings From the All of Us Research Program. Genes (2024)

public healthobesity medicinehuman polymorphismsus research programobesity managementpediatric obesitymetabolic complicationsobesitymcu gene polymorphismshuman geneticshealth sciencespublic health nutrition

Deletion of Sgk1 in Smooth Muscle Cells Induces Sex-Specific Differences in Obesity-Mediated Metabolic Dysfunction and Adipose Tissue Remodeling. Physiology (2024)

physiologycellular physiologymetabolic remodelingmetabolic regulationcell signalingmetabolic syndromemetabolic disordersobesitymetabolismsex-specific differencesadipose tissue remodelingmetabolic pathwayscell metabolismcellular differentiationsmooth muscle cellscell biology

Inverse Regulation of Sgk1 and the Mitochondrial Calcium Uniporter Complex in Aortic Smooth Muscle Cells From Mice and Humans With Obesity and Type 2 Diabetes. Physiology (2023)

obesity medicinediabetescell signalingmetabolismdiabetes researchinverse regulationcell biologymetabolic remodelingmetabolic regulationvascular biologycell metabolisminsulin signalingcellular physiologytype 2metabolic syndromemolecular physiologyphysiologymetabolic pathwayssignal transduction

Mitochondrial Connexins and Mitochondrial Contact Sites With Gap Junction Structure. International Journal of Molecular Sciences (2023)

Selma Cetin-FerraSharon C. FrancisAnthonya T. CooperKit NeikirkAndrea G. MarshallAntentor HintonSandra A. Murray

mitochondrial connexinsbiophysicsmolecular sciencemolecular biologystructural biologygap junction structure

Abstract P3038: Upregulation of the Mitochondrial Calcium Uniporter Abolishes Mitochondrial Dysfunction Associated With Obesity in Vascular Smooth Muscle Cells. Circulation Research (2022)

obesity medicinemitochondrial dynamicsmetabolismcell biologymetabolic remodelingmetabolic regulationvascular biologyobesitycell metabolismmetabolic syndromemolecular metabolismmolecular physiologyabstract p3038physiologypharmacologymitochondrial functionmetabolic pathwayscirculatory physiologyblood vessels

Abstract P430: Vsmcs Increase Glutamine Utilization for Energy Metabolism During Obesity. Circulation Research (2021)

physiologyobesity medicineenergy homeostasisabstract p430energy metabolismobesitymolecular metabolismmetabolismbiochemistrycell metabolism

#3 - Inhibition of the Mitochondrial Calcium Uniporter Reduces Oxidative Phosphorylation in Sgk1-Knockout Vsmc Upon Dietinduced Obesity. (2019)

physiologyobesity medicineenergy homeostasispharmacologymetabolic remodelingmetabolic regulationcell signalingmetabolic syndromemitochondrial functionobesitymolecular metabolismmetabolismmetabolic pathwayscell metabolismoxidative stresscell biology

Abstract 862: Sgk-1 Metabolically Reprograms Vsmc Energy Metabolism by Modulation of Substrate Utilization and Mitochondrial Structure. Circulation Research (2019)

energy metabolismmetabolic remodelingmitochondrial functionabstract 862molecular metabolismsubstrate utilizationmitochondrial structuremolecular biologymetabolismmetabolic engineeringmetabolic pathwaysbiochemistrycell metabolism