Faculty

Institution

Unit

Venue

Shabnam Shalapour

The University of Texas MD Anderson Cancer Center

Affiliations

Center For Rna Interference And Non-Coding Rna

Department Of Cancer Biology

Department Of Immunology

James P. Allison Institute

MD Anderson UTHealth Houston Graduate School

The University of Texas MD Anderson Cancer Center

NoneShabnam Shalapour is currently serving as a Center For Rna Interference And Non-Coding Rna faculty at The University of Texas Md Anderson Cancer Center.

Honors

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Experiences

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Education

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Shabnam Shalapour

The University of Texas MD Anderson Cancer Center

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immunology cancer immunotherapy tumor biology cancer cells cell biology oncogenes cancer biology systems biology tumor microenvironment molecular biology inflammation immune responses cancer research cancer discovery medicinal research immunotherapy immunity (medicine) molecular cancer cell metabolism cellular therapy cellular immune responses colorectal cancer liver cancer tumor heterogeneity hepatocellular carcinoma pancreatic cancer molecular gastroenterology adaptive immune system chronic inflammation anti-inflammatory mitochondrial function gastrointestinal oncology cancer treatment mucosal immunology stem cell research cell transplantation cell death liver transplantation digestive diseases cancer immunosurveillance cancer genetics disease progression liver disease immunosuppression inflammasome activation t-cell-dependent immunogenic chemotherapy anti-tumor immunity clinical investigation leukemia autophagy neuroinflammation inflammatory diseases innate immune system therapy resistance immunosuppressive therapy signaling pathways oral immunotherapy clinical immunology immune mediators immune dysregulation tumor suppressors hepatobiliary tumors malignant disease eternal fight immunosuppressive plasma cells injured liver hybrid periportal hepatocytes liver cancer progenitors malignant progression early colorectal tumorigenesis transformed enterocytes novo lipogenesis nash-driven hcc preclinical models cancer-associated inflammation tumor myofibroblasts

Notable Scholarly Works

Notable Federal Grants

Collaborators

Tu1967 Impact of Renin-Angiotensin-Aldosterone System Inhibitors on Survival in Hepatocellular Carcinoma Patients Receiving Immunotherapy. Gastrointestinal Endoscopy (2026)

gastrointestinal endoscopygastrointestinal oncologygastroenterologyhepatologyurologyhepatocellular carcinomaoncology

Tumor Microenvironment Transcriptional Activity Enables Robust Stratification of Chemotherapy Response in Triple-Negative Breast Cancer. Cell Reports Medicine (2026)

breast oncologybiological microenvironmentstumor biologycancer biologyrobust stratificationcell biologymolecular cancertriple-negative breast cancersystems biologycancer cellstumor microenvironmentbreast cancerchemotherapy response

Distinct Small Molecule Inhibitors of Kras Specifically Prime Ctla4 Blockade Therapy to Transcriptionally Reprogram Tregs and Overcome Resistance to Suppress Pancreas Cancer. bioRxiv (Cold Spring Harbor Laboratory) (2025)

oncogenespancreas cancercancer immunotherapydrug targetscell biologymolecular cancerpancreatic cancermolecular biologytherapeutic targetscancer cells

Abstract 3974: Macronutrient Composition Dictates Mash-Associated Hcc Immunosurveillance Through Microbiota Alteration and Metabolic Adaptation. Cancer Research (2024)

Nicolas T. RyujinJian HuangAlbert NguyenJared EdwardsYuhe ChengJessica WenAshish DamaniaNadim AjamiSpencer RosarioMark LongLudmil AlexandrovShabnam Shalapour

immunologymicrobiota alterationcancer researchmetabolic adaptationmacronutrient compositionhealth sciencesoncologycancer biology

Abstract B064: Antigen-Presenting Type-I Conventional Dendritic Cells Facilitate Curative Checkpoint Blockade Immunotherapy in Pancreatic Cancer. Cancer Research (2024)

Krishnan K MahadevanAllison M. DyevoichYang ChenBingrui LiHikaru SugimotoAmari SockwellKathleen McAndrewsHuamin WangShabnam ShalapourStephanie WatowichRaghu Kalluri

oncogenespathologytumor targetingoncologycancer immunotherapyimmunologymedicinal researchimmunotherapycellular therapycancer researchpancreatic cancersystems biologycancer cellscancer treatmentimmune checkpoint inhibitorstumor microenvironmentcancer biology

B Cells Spatial Organization Defines Their Phenotype and Function in Cancer “Tell Me With Whom You Consort, and I Will Tell You Who You Are” ― Goethe. Current Opinion in Immunology (2024)

cancer “ telltumor biologycell interactions” ―cell biologycarcinogenesiscancer researchsystems biologycancer cellscancer lettertumor microenvironmentcancer biologytumor heterogeneity

Development of an Engineered Extracellular Vesicles-Based Vaccine Platform for Combined Delivery of Mrna and Protein to Induce Functional Immunity. Journal of Controlled Release (2024)

Xin LuoKathleen M McAndrewsKent A ArianSami J MorseViktoria BoekerShreyasee V KumbharYingying HuKrishnan K MahadevanKaira A ChurchSriram ChittaNicolas T RyujinJanine HenselJianli DaiDara P DowlatshahiHikaru SugimotoMichelle L KirtleyValerie S LeBleuShabnam ShalapourJoe H SimmonsRaghu Kalluri

biological engineeringgene deliverycombined deliveryvaccine developmentimmunologyvaccinationfunctional immunitybiomedical engineeringprotein engineering

Il-22 Resolves Masld via Enterocyte Stat3 Restoration of Diet-Perturbed Intestinal Homeostasis. Cell Metabolism (2024)

Peng ZhangJunlai LiuAllen LeeIrene TsaurMasafumi OhiraVivian DuongNicholas VoKosuke WatariHua SuJu Youn KimLi GuMandy ZhuShabnam ShalapourMojgan HosseiniGautam BandyopadhyaySuling ZengCristina LlorenteHaoqi Nina ZhaoSantosh LamichhaneSiddharth MohanPieter C DorresteinJerrold M OlefskyBernd SchnablPejman SorooshMichael Karin

gut-organ axismetabolismenergy metabolismdiet-perturbed intestinal homeostasiscell biologydigestive diseasescell metabolisminflammatory bowel diseasemolecular biologysystems biology

Type I Conventional Dendritic Cells Facilitate Immunotherapy in Pancreatic Cancer. Science (2024)

Krishnan K. MahadevanAllison M. DyevoichYang ChenBingrui LiHikaru SugimotoAmari M. SockwellKathleen M. McAndrewsLakshmi Kavitha SthanamHuamin WangShabnam ShalapourStephanie S. WatowichRaghu Kalluri

oncogenestumor biologycancer immunotherapyimmunologycell biologycell transplantationimmunotherapymedicinal researchcellular therapysynthetic immunologycellular immune responsesimmunity (medicine)pancreatic cancerimmune checkpoint inhibitorssystems biologycancer cellsimmunoeditingtumor microenvironment

Angiotensin II Receptor Inhibition Ameliorates Liver Fibrosis and Enhances Hepatocellular Carcinoma Infiltration by Effector T Cells. Proceedings of the National Academy of Sciences (2023)

Li GuYahui ZhuMaiya LeeAlbert NguyenNicolas T. RyujinJian Yu HuangShusil K. PanditShadi ChamseddineLianchun XiaoYehia I. MohamedAhmed O. KasebMichael KarinShabnam Shalapour

fibrosiscancer immunotherapyliver fibrosisimmunologyhepatocellular carcinomacancer biology

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Shabnam Shalapour

The University of Texas MD Anderson Cancer Center

Affiliations

Center For Rna Interference And Non-Coding Rna

Department Of Cancer Biology

Department Of Immunology

James P. Allison Institute

MD Anderson UTHealth Houston Graduate School

The University of Texas MD Anderson Cancer Center

NoneShabnam Shalapour is currently serving as a Center For Rna Interference And Non-Coding Rna faculty at The University of Texas Md Anderson Cancer Center.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Shabnam Shalapour

The University of Texas MD Anderson Cancer Center

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Tu1967 Impact of Renin-Angiotensin-Aldosterone System Inhibitors on Survival in Hepatocellular Carcinoma Patients Receiving Immunotherapy. Gastrointestinal Endoscopy (2026)

gastrointestinal endoscopygastrointestinal oncologygastroenterologyhepatologyurologyhepatocellular carcinomaoncology

Tumor Microenvironment Transcriptional Activity Enables Robust Stratification of Chemotherapy Response in Triple-Negative Breast Cancer. Cell Reports Medicine (2026)

oncogenespancreas cancercancer immunotherapydrug targetscell biologymolecular cancerpancreatic cancermolecular biologytherapeutic targetscancer cells

Abstract 3974: Macronutrient Composition Dictates Mash-Associated Hcc Immunosurveillance Through Microbiota Alteration and Metabolic Adaptation. Cancer Research (2024)

Nicolas T. RyujinJian HuangAlbert NguyenJared EdwardsYuhe ChengJessica WenAshish DamaniaNadim AjamiSpencer RosarioMark LongLudmil AlexandrovShabnam Shalapour

immunologymicrobiota alterationcancer researchmetabolic adaptationmacronutrient compositionhealth sciencesoncologycancer biology

Abstract B064: Antigen-Presenting Type-I Conventional Dendritic Cells Facilitate Curative Checkpoint Blockade Immunotherapy in Pancreatic Cancer. Cancer Research (2024)

Krishnan K MahadevanAllison M. DyevoichYang ChenBingrui LiHikaru SugimotoAmari SockwellKathleen McAndrewsHuamin WangShabnam ShalapourStephanie WatowichRaghu Kalluri

B Cells Spatial Organization Defines Their Phenotype and Function in Cancer “Tell Me With Whom You Consort, and I Will Tell You Who You Are” ― Goethe. Current Opinion in Immunology (2024)

cancer “ telltumor biologycell interactions” ―cell biologycarcinogenesiscancer researchsystems biologycancer cellscancer lettertumor microenvironmentcancer biologytumor heterogeneity

Development of an Engineered Extracellular Vesicles-Based Vaccine Platform for Combined Delivery of Mrna and Protein to Induce Functional Immunity. Journal of Controlled Release (2024)

biological engineeringgene deliverycombined deliveryvaccine developmentimmunologyvaccinationfunctional immunitybiomedical engineeringprotein engineering

Il-22 Resolves Masld via Enterocyte Stat3 Restoration of Diet-Perturbed Intestinal Homeostasis. Cell Metabolism (2024)

gut-organ axismetabolismenergy metabolismdiet-perturbed intestinal homeostasiscell biologydigestive diseasescell metabolisminflammatory bowel diseasemolecular biologysystems biology

Type I Conventional Dendritic Cells Facilitate Immunotherapy in Pancreatic Cancer. Science (2024)

Krishnan K. MahadevanAllison M. DyevoichYang ChenBingrui LiHikaru SugimotoAmari M. SockwellKathleen M. McAndrewsLakshmi Kavitha SthanamHuamin WangShabnam ShalapourStephanie S. WatowichRaghu Kalluri

Angiotensin II Receptor Inhibition Ameliorates Liver Fibrosis and Enhances Hepatocellular Carcinoma Infiltration by Effector T Cells. Proceedings of the National Academy of Sciences (2023)

Li GuYahui ZhuMaiya LeeAlbert NguyenNicolas T. RyujinJian Yu HuangShusil K. PanditShadi ChamseddineLianchun XiaoYehia I. MohamedAhmed O. KasebMichael KarinShabnam Shalapour

fibrosiscancer immunotherapyliver fibrosisimmunologyhepatocellular carcinomacancer biology

1
2
3
4
5
10 / page