Faculty

Institution

Unit

Venue

Seth Guller

Senior Research Scientist in Obstetrics Gynecology and Reproductive Sciences

Yale University

Affiliations

Obstetrics, Gynecology & Reproductive Sciences

Seth Guller is currently serving as an Obstetrics, Gynecology & Reproductive Sciences Senior Research Scientist in Obstetrics Gynecology and Reproductive Sciences at Yale University.

Honors

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Experiences

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Education

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Seth Guller

Yale University

Senior Research Scientist in Obstetrics Gynecology and Reproductive Sciences

You can click a keyword to filter the displayed items

immunology gynecology cell biology reproductive medicine obstetrics and gynaecology endocrinology reproductive biology pharmacology maternal health fetal medicine hematology maternal-fetal medicine immune responses reproductive immunology gene expression obstetrics membrane biology inflammation reproductive health reproductive science veterinary medicine human reproduction mammalian biology endocrine research cell regulation human placenta vascular biology growth hormone assisted reproduction glucocorticoids placental development cytokines liver physiology medicinal research comparative endocrinology reproductive physiology clinical immunology developmental endocrinology steroid metabolism hofbauer cells thrombosis innate immune system cell migration high-risk pregnancies hypoxia (medicine) human fetal membranes clinical biochemistry matrix biology respiratory medicine preterm birth virus-host interactions transcription regulation viral pathogenesis maternal-fetal interface human cytotrophoblasts protein science cell-matrix interactions immunopathology female reproductive system apoptosis mammalian physiology placental hofbauer cells endothelial cells preadipose cells fibronectin expression fas ligand cell lineage protein expression herbal medicine developmental immunology placental villi viral infection fetal survival human term placentas human decidua immune privilege

Notable Scholarly Works

Notable Federal Grants

Collaborators

Distinct Transcriptional and Epigenomic Programs Define Hofbauer Cells in Term Placenta. JCI Insight (2025)

developmental biologyplacental developmentepigeneticsreproductive immunologycell biologymolecular cell biologyepigenomicsgene expression

Extracellular Vesicles From M1 and M2 Macrophages Elicit Sexually Dimorphic Responses in the Human Placenta. Placenta (2025)

developmental biologyfemale reproductive systemreproductive scienceplacental developmentreproductive immunologycell biologyhuman placentareproductive medicinereproductive endocrinologyextracellular microvesiclesembryologyreproductive biologyextracellular vesiclesoogenesisphagocytes

Role of Serotonin on Gene Expression and Physiology in Human Cytotrophoblasts and Placenta. Endocrinology (2025)

developmental biologyplacental developmentneuropharmacologycell biologyneurosciencemolecular psychiatryneurogeneticshuman cytotrophoblastsgene expressionbiological psychiatry

Serotonin Impact in Human Trophoblast Cells: Serotonylation, Gene Regulation, Phenotype, and Potential Physiopathology. Placenta (2025)

developmental biologypotential physiopathologyneuropharmacologymolecular neurosciencecell biologyserotonin impactmolecular psychiatryhuman trophoblast cellsbiological psychiatry

Quantitative Proteomics Reveals Differential Extracellular Vesicle Cargo From M1 and M2 Monocyte-Derived Human Macrophages. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Paschalia PantaziToby ClementsHarriet T ParsonsMyrsini KaforouKate J HeesomPhillip R BennettSeth GullerVikki M AbrahamsBeth Holder

molecular biologyproteomicsextracellular microvesicles

Leptin-Mediated Induction of Il-6 Expression in Hofbauer Cells Contributes to Preeclampsia Pathogenesis. International Journal of Molecular Sciences (2023)

Asli OzmenChinedu NwabuobiZhonghua TangXiaofang GuoKellie LarsenSeth GullerJacqueline BlasMonica MooreUmit A. KayisliCharles J. LockwoodOzlem Guzeloglu-Kayisli

hofbauer cellsimmune responsesgene expressionreproductive immunologycell regulationleptin-mediated inductionmolecular sciencecell biologycell signalingimmunologyinnate immune systemsignal transductionmolecular biologymolecular medicinemedicinal research

Characterization of Extracellular Vesicles From Placental Macrophages (Hofbauer Cells) in Normal Physiology and Infection. Placenta (2022)

Paschalia PantaziMyrsini KaforouSeth GullerZhonghua TangToby ClementsBeth Holder

hematologyinfectious diseasescell biologynormal physiologyimmunologyextracellular vesiclesplacental macrophages

Contributors. Elsevier eBooks (2022)

Ron AltermanJeffrey E. ArleKerry BradleySergio CanaveroSteven M. FalowskiChad W. FarleyYakov GologorskyJianwen Wendy GuH. Louis JournéeJohn KastOlga KhazenJoachim K. KraussVignessh KumarMark LentRobert M. LevyAndres M. LozanoCharles MackelGeorge T. MandyburBryan L. McLaughlinDaniel R. MerrillAlon Y. MogilnerGabi MolnarGuillermo A. MonsalveRichard B. NorthYunseo Linda ParkJohn ParkerShrey PatelJulie G. PilitsisFrancisco A. PonceJason E. PopeAdolfo Ramirez-ZamoraLouis J. RasoJoshua M. RosenowJay L. ShilsPeter SingleKonstantin V. SlavinMichael D. StaudtMark M. SteckerHuy Q. Truong

Insulin Increases Placental Triglyceride as a Potential Mechanism for Fetal Adiposity in Maternal Obesity. Molecular Metabolism (2022)

Anika K. AnamKatherine M. CookeMilana Bochkur DratverJane V. O'BryanLauren E. PerleySeth M. GullerJanice J. HwangHugh S. TaylorLeigh GoedekeHarvey J. KlimanDaniel F. VatnerClare A. Flannery

drug metabolismpharmacologynutritional biochemistryfetal adipositymolecular nutritionmolecular physiologymetabolismliver physiologypotential mechanismmembrane biologymetabolic regulationredox biologylipid nutritionbiochemistryphysiologymaternal obesityinsulin signalingmolecular metabolismendocrinologynutritionenergy metabolism

Placental Macrophage (Hofbauer Cell) Response to Viral and Bacterial Ligands is Influenced by Fetal Sex. Research Square (2022)

Paschalia PantaziMyrsini KaforouZhonghua TangVikki AbrahamsAndrew McArdleSeth GullerBeth Holder

virologyimmune responsesbacterial ligandsdermatologyvirus-host interactionsimmunologyhofbauer cellviral pathogenesisplacental macrophagefetal sexhealth sciencesfetal medicinemedicinal researchvirus research

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Seth Guller

Senior Research Scientist in Obstetrics Gynecology and Reproductive Sciences

Yale University

Affiliations

Obstetrics, Gynecology & Reproductive Sciences

Seth Guller is currently serving as an Obstetrics, Gynecology & Reproductive Sciences Senior Research Scientist in Obstetrics Gynecology and Reproductive Sciences at Yale University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Seth Guller

Yale University

Senior Research Scientist in Obstetrics Gynecology and Reproductive Sciences

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Distinct Transcriptional and Epigenomic Programs Define Hofbauer Cells in Term Placenta. JCI Insight (2025)

developmental biologyplacental developmentepigeneticsreproductive immunologycell biologymolecular cell biologyepigenomicsgene expression

Extracellular Vesicles From M1 and M2 Macrophages Elicit Sexually Dimorphic Responses in the Human Placenta. Placenta (2025)

Role of Serotonin on Gene Expression and Physiology in Human Cytotrophoblasts and Placenta. Endocrinology (2025)

developmental biologyplacental developmentneuropharmacologycell biologyneurosciencemolecular psychiatryneurogeneticshuman cytotrophoblastsgene expressionbiological psychiatry

Serotonin Impact in Human Trophoblast Cells: Serotonylation, Gene Regulation, Phenotype, and Potential Physiopathology. Placenta (2025)

developmental biologypotential physiopathologyneuropharmacologymolecular neurosciencecell biologyserotonin impactmolecular psychiatryhuman trophoblast cellsbiological psychiatry

Quantitative Proteomics Reveals Differential Extracellular Vesicle Cargo From M1 and M2 Monocyte-Derived Human Macrophages. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Paschalia PantaziToby ClementsHarriet T ParsonsMyrsini KaforouKate J HeesomPhillip R BennettSeth GullerVikki M AbrahamsBeth Holder

molecular biologyproteomicsextracellular microvesicles

Leptin-Mediated Induction of Il-6 Expression in Hofbauer Cells Contributes to Preeclampsia Pathogenesis. International Journal of Molecular Sciences (2023)

Asli OzmenChinedu NwabuobiZhonghua TangXiaofang GuoKellie LarsenSeth GullerJacqueline BlasMonica MooreUmit A. KayisliCharles J. LockwoodOzlem Guzeloglu-Kayisli

Characterization of Extracellular Vesicles From Placental Macrophages (Hofbauer Cells) in Normal Physiology and Infection. Placenta (2022)

Paschalia PantaziMyrsini KaforouSeth GullerZhonghua TangToby ClementsBeth Holder

hematologyinfectious diseasescell biologynormal physiologyimmunologyextracellular vesiclesplacental macrophages

Contributors. Elsevier eBooks (2022)

Insulin Increases Placental Triglyceride as a Potential Mechanism for Fetal Adiposity in Maternal Obesity. Molecular Metabolism (2022)

Anika K. AnamKatherine M. CookeMilana Bochkur DratverJane V. O'BryanLauren E. PerleySeth M. GullerJanice J. HwangHugh S. TaylorLeigh GoedekeHarvey J. KlimanDaniel F. VatnerClare A. Flannery

Placental Macrophage (Hofbauer Cell) Response to Viral and Bacterial Ligands is Influenced by Fetal Sex. Research Square (2022)

Paschalia PantaziMyrsini KaforouZhonghua TangVikki AbrahamsAndrew McArdleSeth GullerBeth Holder

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