Faculty

Institution

Unit

Venue

Scott Landfear

Oregon Health & Science University

Affiliations

OGI School of Science and Engineering

Department Of Chemistry, Biochemistry And Molecular Biology

Oregon Health & Science University

NoneScott Landfear is currently serving as a Chemistry, Biochemistry And Molecular Biology faculty at Oregon Health & Science University.

Honors

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Experiences

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Education

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Scott Landfear

Oregon Health & Science University

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molecular biology biochemistry visceral leishmaniasis parasitology biological chemistry membrane biology protein transport microbiology membrane proteins parasitic protozoa molecular and cellular biology pharmacology membrane transport molecular genetics gene expression african trypanosomiasis protein science nucleic acids enzyme inhibition molecular metabolism cellular biochemistry cell metabolism biochemical sciences neglected tropical diseases molecular cell biology drug discovery cell and molecular biology molecular physiology intracellular trafficking invertebrate pathology parasite genomics host-parasite relationships bioenergetics structural molecular biology rna biology liver physiology cellular physiology biochemical genetics antiparasitic agent gene transfer microbial genetics molecular microbiology leishmania donovani energy metabolism gene delivery biomolecular interactions molecular regulation gene regulation lead identification secretory pathway plasmodium falciparum transport-deficient mutant leishmania enriettii functional expression leishmania mexicana antileishmanial agents biological inorganic chemistry gene characterization nutrient physiology gene vector host factors sequence analysis molecular biotechnology integrative biology receptor (biochemistry) protists treatment and prevention neglected diseases transporter gene functional characterization methylarsonous acid arsenic trioxide leishmania gene functional rescue arsenic transport zebrafish aquaglyceroporins

Notable Scholarly Works

Notable Federal Grants

Collaborators

Discovery and Optimization of Tambjamines as a Novel Class of Antileishmanial Agents. Journal of Medicinal Chemistry (2024)

Papireddy KancharlaDiana OrtizCorinne M. FargoXiaowei ZhangYuexin LiMarco SanchezAmrendra KumarMonish YeluguriRozalia A. DodeanDiana CaridhaMichael S. MadejczykMonica MartinXiannu JinCameron BlountRavi ChetreeKristina PannoneHieu T. DinhJesse DeLucaMartin EvansRobert NadeauChau VuongSusan LeedWilliam E. DennisNorma RoncalBrandon S. PybusPatricia J. LeeAlison RothKevin A. ReynoldsJane X. KellyScott M. Landfear

antileishmanial agentsmedicinal chemistrynovel classpharmacologydrug discovery

Synthesis and Biological Evaluation of 4,7,9-Trisubstituted Benzoxazepines as Antileishmanial Agents. Bioorganic & Medicinal Chemistry Letters (2024)

Tara Man KadayatStefan KwiatkowskiDiana OrtizGaurav ShoeranJared T HammillHo Shin KimJoanna CholewoScott M LandfearR Kiplin Guy

antileishmanial agentsbiological evaluationpharmaceutical chemistrybioactive compoundsmedicinal chemistrybioorganic chemistrybiological chemistrybiochemistrymedicinal research

Ties That Bind Us: Leishmania Grasps the Sandfly. Trends in Parasitology (2024)

parasitologyvisceral leishmaniasishost-parasite relationshipsinsect sciencebiologyevolutionary biologysocial parasitism

Optimization of Orally Bioavailable Antileishmanial 2,4,5-Trisubstituted Benzamides. Journal of Medicinal Chemistry (2023)

Ho Shin KimDiana OrtizTara Man KadayatCorinne M. FargoJared T. HammillYizhe ChenAmy L. RiceKristin L. BegleyGaurav ShoeranWilliam PistelPhillip A. YatesMarco A. SanchezScott M. LandfearR. Kiplin Guy

medicinal chemistrydrug discoverypharmacology

New Vistas in the Biology of the Flagellum—Leishmania Parasites. Pathogens (2022)

parasitologymicrobiologyparasitic protozoavisceral leishmaniasisinfectious diseaseshost-parasite relationshipsbiologypathogensveterinary parasitology

Amino-Substituted 3-Aryl- and 3-Heteroarylquinolines as Potential Antileishmanial Agents. Journal of Medicinal Chemistry (2021)

Jared T. HammillVitaliy M. SviripaLiliia M. KrilDiana OrtizCorinne M. FargoHo Shin KimYizhe ChenJonah RectorAmy L. RiceMalgorzata A. DomagalskaKristin L. BegleyChunming LiuVivek M. RangnekarJean-Claude DujardinDavid S. WattScott M. LandfearR. Kiplin Guy

medicinal chemistrypharmacology

A Cytoskeletal Protein Complex is Essential for Division of Intracellular Amastigotes of Leishmania Mexicana. Journal of Biological Chemistry (2020)

parasitic protozoacytoskeletonmolecular and cellular biologyvisceral leishmaniasisprotein structurebiological chemistrybiochemistrymolecular biologycellular biochemistry

Distinct Cis -Acting Elements Govern Purine-Responsive Regulation of the Leishmania Donovani Nucleoside Transporters, Ldnt1 and Ldnt2. bioRxiv (Cold Spring Harbor Laboratory) (2020)

parasitic protozoavisceral leishmaniasismolecular and cellular biologynucleic acidsbiochemical interactionmolecular cell biologymembrane proteinssystems biologybiochemistrymolecular biologyenzyme inhibition

Nutrient Sensing in Leishmania: Flagellum and Cytosol. Molecular Microbiology (2020)

microbiologyparasitic protozoavisceral leishmaniasisfungal ecologymicroorganisms

The Trypanosoma Brucei Cytoskeletal Protein Kharon Associates With Partner Proteins to Mediate Both Cytokinesis and Trafficking of Flagellar Membrane Proteins. bioRxiv (Cold Spring Harbor Laboratory) (2020)

microbiologyafrican trypanosomiasiscytoskeletoncell biologymolecular cell biologyprotein sciencemembrane proteinsintracellular traffickingmolecular biology

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Scott Landfear

Oregon Health & Science University

Affiliations

OGI School of Science and Engineering

Department Of Chemistry, Biochemistry And Molecular Biology

Oregon Health & Science University

NoneScott Landfear is currently serving as a Chemistry, Biochemistry And Molecular Biology faculty at Oregon Health & Science University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Scott Landfear

Oregon Health & Science University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Discovery and Optimization of Tambjamines as a Novel Class of Antileishmanial Agents. Journal of Medicinal Chemistry (2024)

antileishmanial agentsmedicinal chemistrynovel classpharmacologydrug discovery

Synthesis and Biological Evaluation of 4,7,9-Trisubstituted Benzoxazepines as Antileishmanial Agents. Bioorganic & Medicinal Chemistry Letters (2024)

Tara Man KadayatStefan KwiatkowskiDiana OrtizGaurav ShoeranJared T HammillHo Shin KimJoanna CholewoScott M LandfearR Kiplin Guy

antileishmanial agentsbiological evaluationpharmaceutical chemistrybioactive compoundsmedicinal chemistrybioorganic chemistrybiological chemistrybiochemistrymedicinal research

Ties That Bind Us: Leishmania Grasps the Sandfly. Trends in Parasitology (2024)

parasitologyvisceral leishmaniasishost-parasite relationshipsinsect sciencebiologyevolutionary biologysocial parasitism

Optimization of Orally Bioavailable Antileishmanial 2,4,5-Trisubstituted Benzamides. Journal of Medicinal Chemistry (2023)

Ho Shin KimDiana OrtizTara Man KadayatCorinne M. FargoJared T. HammillYizhe ChenAmy L. RiceKristin L. BegleyGaurav ShoeranWilliam PistelPhillip A. YatesMarco A. SanchezScott M. LandfearR. Kiplin Guy

medicinal chemistrydrug discoverypharmacology

New Vistas in the Biology of the Flagellum—Leishmania Parasites. Pathogens (2022)

parasitologymicrobiologyparasitic protozoavisceral leishmaniasisinfectious diseaseshost-parasite relationshipsbiologypathogensveterinary parasitology

Amino-Substituted 3-Aryl- and 3-Heteroarylquinolines as Potential Antileishmanial Agents. Journal of Medicinal Chemistry (2021)

medicinal chemistrypharmacology

A Cytoskeletal Protein Complex is Essential for Division of Intracellular Amastigotes of Leishmania Mexicana. Journal of Biological Chemistry (2020)

parasitic protozoacytoskeletonmolecular and cellular biologyvisceral leishmaniasisprotein structurebiological chemistrybiochemistrymolecular biologycellular biochemistry

Distinct Cis -Acting Elements Govern Purine-Responsive Regulation of the Leishmania Donovani Nucleoside Transporters, Ldnt1 and Ldnt2. bioRxiv (Cold Spring Harbor Laboratory) (2020)

Nutrient Sensing in Leishmania: Flagellum and Cytosol. Molecular Microbiology (2020)

microbiologyparasitic protozoavisceral leishmaniasisfungal ecologymicroorganisms

microbiologyafrican trypanosomiasiscytoskeletoncell biologymolecular cell biologyprotein sciencemembrane proteinsintracellular traffickingmolecular biology

1
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3
4
5
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10 / page