Faculty

Institution

Unit

Venue

Sajish Mathew

Assistant Professor

University of South Carolina

Affiliations

College of Pharmacy

Department of Drug Discovery and Biomedical Sciences (ddbs)

Sajish Mathew is currently serving as a College Of Pharmacy Assistant Professor at University of South Carolina.

Honors

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Experiences

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Education

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Sajish Mathew

University of South Carolina

Assistant Professor

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pharmacology medicinal research health sciences signal transduction neuroscience inflammation cancer research oncology molecular neuroscience neuropharmacology peptide science protein science molecular neurobiology global health gastroenterology hepatology enzyme inhibition brain tumor research vascular biology molecular science molecular physiology biological chemistry cancer care peptides free radical biology redox biology colorectal cancer anti-inflammatory therapeutic efficacy neurochemistry clinical neuroscience dopamine cellular neurobiology treatment and prevention enzyme specificity inhibitory activity tumor heterogeneity molecular evidence in vivo systems cutaneous biology mast cell disorders redox signaling localized excited state metabolic regulation cannabis use cancer management cancer treatment cancer biology breast oncology gene function neuroinflammation receptor tyrosine kinases rna biology current views early-onset colorectal cancer anti-inflammatory properties genomic remodeling histone serine-adp-ribosylation skin inflammation mast cell short-term administrations neuronal dendrites arc stability ubiquitin-independent pathway camp-ros-dna damage axis tyrrs-mediated dna repair energy metabolism metabolic remodeling metabolic syndrome molecular metabolism molecular biology metabolism metabolic dysfunction biochemistry

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract Po4-23-10: Restoring the Efficacy of Standard of Care in Treatment-Refractory Er+ Breast Cancer by Re-Activation of Camp-Ros-Dna Damage Axis. Cancer Research (2024)

Ozge SaatciMetin CetinMeral UnerUnal Metin TokatIoulia ChatzistamouPelin Gulizar ErsanElodie MontaudonAytekin AkyolSercan AksoyAysegul UnerElisabetta MarangoniSajish MathewOzgur Sahin

breast oncologyradiation oncologycamp-ros-dna damage axiscancer biologymedicinal researchcancer researchmedicinepharmacologycancer managementclinical researchcancer treatmentcancer careoncologybreast cancer

Tau Regulates Arc Stability in Neuronal Dendrites via a Proteasome-Sensitive but Ubiquitin-Independent Pathway. Journal of Biological Chemistry (2024)

Dina W YakoutAnkit ShroffWei WeiVishrut ThakerZachary D AllenMathew SajishTaras Y NazarkoAngela M Mabb

ubiquitin-independent pathwayarc stabilitybiochemistryneuronal dendritesbiological chemistry

Resveratrol Protects Against Skin Inflammation Through Inhibition of Mast Cell, Sphingosine Kinase-1, Stat3 and Nf-κB P65 Signaling Activation in Mice. International Journal of Molecular Sciences (2023)

Christopher D. CarlucciYvonne HuiAlena P. ChumanevichPiper A. RobidaJohn W. FuselerMathew SajishPrakash NagarkattiMitzi NagarkattiCarole A. Oskeritzian

redox signalingdermatologypharmacologymast cell disordersvascular biologylocalized excited statephysiologymolecular scienceskin inflammationcutaneous biologyreceptorsmedicinal researchinflammationregenerative medicinepeptide sciencemast cellmolecular physiologymembrane biologyin vivo systemssignal transduction

Cis- and Trans-Resveratrol Have Opposite Effects on Histone Serine-Adp-Ribosylation and Tyrosine Induced Neurodegeneration. Nature Communications (2022)

Megha JhanjiChintada Nageswara RaoJacob C. MasseyMarion C. HopeXueyan ZhouC. Dirk KeeneTao MaMichael D. WyattJason A. StewartMathew Sajish

neurologyenzyme specificityscientific communicationinhibitory activitytumor biologyhistone serine-adp-ribosylationprotein sciencetreatment and preventionmedicinal researchpeptide sciencebrain tumor researchpharmacologygene expressionenzyme inhibitionhealth sciencesmolecular evidencetumor heterogeneity

Tyrosine Inhibits Tyrrs-Mediated Dna Repair and Induces Neuronal Oxidative Dna Damage. Research Square (Research Square) (2021)

Megha JhanjiChintada Nageswara RaoXueyan ZhouC KeeneTao MaJason StewartMathew Sajish

neuropharmacologymolecular neurobiologyneurosciencepharmacologyphysiologyneuroinflammationpeptidesmolecular neurosciencedna repairreceptor tyrosine kinasesmedicinal researchtyrrs-mediated dna repairrna biologyprotein sciencemembrane biologygene functionfree radical biologysignal transductionredox biology

Early-Onset Colorectal Cancer: Initial Clues and Current Views. Nature Reviews Gastroenterology & Hepatology (2020)

Lorne J. HofsethJames R. HebertAnindya ChandaHexin ChenBryan L. LoveMaria M. PenaE. Angela MurphyMathew SajishAmit ShethPhillip J. BuckhaultsFranklin G. Berger

colorectal cancergastroenterologyhepatologyglobal healthcancer researchcurrent viewsearly-onset colorectal cancerhealth sciencesoncology

Acute and Short-Term Administrations of Delta-9-Tetrahydrocannabinol Modulate Major Gut Metabolomic Regulatory Pathways in C57Bl/6 Mice. Scientific Reports (2019)

Megha OzaWilliam BeckerPhani M. GummadidalaTravis DiasMayomi H. OmebeyinjeLi ChenChandrani MitraRubaiya JesminParamita ChakrabortyMathew SajishLorne J. HofsethKoyeli BanerjeeQian WangPeter D. R. MoellerMitzi NagarkattiPrakash NagarkattiAnindya Chanda

metabolismcell signalingmetabolic regulationcannabis useshort-term administrationsmetabolomicspharmacology

Nicotinamide Augments the Anti-Inflammatory Properties of Resveratrol Through Parp1 Activation. Scientific Reports (2019)

Maria YanezMegha JhanjiKendall MurphyR. Michael GowerMathew SajishEhsan Jabbarzadeh

inflammationanti-inflammatorymedicinal researchanti-inflammatory propertiespharmacologyhealth sciencestherapeutic efficacy

Dopamine Triggers Ctcf-Dependent Morphological and Genomic Remodeling of Astrocytes. Journal of Neuroscience (2018)

Ashley GallowayAdewale AdeluyiBernadette O'DonovanMiranda L. FisherChintada Nageswara RaoPeyton CritchfieldMathew SajishJill R. TurnerPavel I. Ortinski

neurochemistryneuropharmacologyneuroanatomycellular neurobiologycell biologydevelopmental neurobiologyneurosciencedopaminemolecular neurobiologygenomic remodelingpharmacologyclinical neurosciencemolecular neurosciencesignal transduction

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Sajish Mathew

Assistant Professor

University of South Carolina

Affiliations

College of Pharmacy

Department of Drug Discovery and Biomedical Sciences (ddbs)

Sajish Mathew is currently serving as a College Of Pharmacy Assistant Professor at University of South Carolina.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Sajish Mathew

University of South Carolina

Assistant Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract Po4-23-10: Restoring the Efficacy of Standard of Care in Treatment-Refractory Er+ Breast Cancer by Re-Activation of Camp-Ros-Dna Damage Axis. Cancer Research (2024)

Ozge SaatciMetin CetinMeral UnerUnal Metin TokatIoulia ChatzistamouPelin Gulizar ErsanElodie MontaudonAytekin AkyolSercan AksoyAysegul UnerElisabetta MarangoniSajish MathewOzgur Sahin

Tau Regulates Arc Stability in Neuronal Dendrites via a Proteasome-Sensitive but Ubiquitin-Independent Pathway. Journal of Biological Chemistry (2024)

Dina W YakoutAnkit ShroffWei WeiVishrut ThakerZachary D AllenMathew SajishTaras Y NazarkoAngela M Mabb

ubiquitin-independent pathwayarc stabilitybiochemistryneuronal dendritesbiological chemistry

Christopher D. CarlucciYvonne HuiAlena P. ChumanevichPiper A. RobidaJohn W. FuselerMathew SajishPrakash NagarkattiMitzi NagarkattiCarole A. Oskeritzian

Cis- and Trans-Resveratrol Have Opposite Effects on Histone Serine-Adp-Ribosylation and Tyrosine Induced Neurodegeneration. Nature Communications (2022)

Megha JhanjiChintada Nageswara RaoJacob C. MasseyMarion C. HopeXueyan ZhouC. Dirk KeeneTao MaMichael D. WyattJason A. StewartMathew Sajish

Tyrosine Inhibits Tyrrs-Mediated Dna Repair and Induces Neuronal Oxidative Dna Damage. Research Square (Research Square) (2021)

Megha JhanjiChintada Nageswara RaoXueyan ZhouC KeeneTao MaJason StewartMathew Sajish

Early-Onset Colorectal Cancer: Initial Clues and Current Views. Nature Reviews Gastroenterology & Hepatology (2020)

Lorne J. HofsethJames R. HebertAnindya ChandaHexin ChenBryan L. LoveMaria M. PenaE. Angela MurphyMathew SajishAmit ShethPhillip J. BuckhaultsFranklin G. Berger

colorectal cancergastroenterologyhepatologyglobal healthcancer researchcurrent viewsearly-onset colorectal cancerhealth sciencesoncology

Acute and Short-Term Administrations of Delta-9-Tetrahydrocannabinol Modulate Major Gut Metabolomic Regulatory Pathways in C57Bl/6 Mice. Scientific Reports (2019)

metabolismcell signalingmetabolic regulationcannabis useshort-term administrationsmetabolomicspharmacology

Nicotinamide Augments the Anti-Inflammatory Properties of Resveratrol Through Parp1 Activation. Scientific Reports (2019)

Maria YanezMegha JhanjiKendall MurphyR. Michael GowerMathew SajishEhsan Jabbarzadeh

inflammationanti-inflammatorymedicinal researchanti-inflammatory propertiespharmacologyhealth sciencestherapeutic efficacy

Dopamine Triggers Ctcf-Dependent Morphological and Genomic Remodeling of Astrocytes. Journal of Neuroscience (2018)

Ashley GallowayAdewale AdeluyiBernadette O'DonovanMiranda L. FisherChintada Nageswara RaoPeyton CritchfieldMathew SajishJill R. TurnerPavel I. Ortinski

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