Faculty

Institution

Unit

Venue

Robert P. Searles

Oregon Health & Science University

Affiliations

Center Of Knight Cancer

OHSU School of Medicine

Center Of Portland Alcohol Research

Department of Medicine

Division Of Hematology/Medical Oncology

Institute Of Knight Cancer Insitute

Institute Of University Knight Cancer

OHSU Knight Cancer Institute

Oregon Health & Science University

NoneRobert P. Searles is currently serving as a Center Of Knight Cancer faculty at Oregon Health & Science University.

Honors

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Experiences

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Education

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Robert P. Searles

Oregon Health & Science University

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genetics gene expression neuroscience molecular biology genomics genome biology physiology behavioral neuroscience addiction biology alcohol (drug) alcohol dependence cancer research bioinformatics neurogenetics neuropsychopharmacology functional genomics leukemia medical virology addictive behaviors molecular diagnostics nucleic acids myeloid neoplasia hematological malignancies cancer genomics microarray data analysis transcriptomics technology next-generation sequencing rna biology brain transcriptome chronic ethanol consumption rhesus macaques oncogenes general virology virus research heredity reproductive biology reproductive medicine substance use molecular physiology anti-cancer agents cancer genetics medical genetics endocrine mechanisms reproductive hormones receptor (biochemistry) knockout mice molecular neurobiology brain science alcohol misuse alcohol-related liver disease acute myeloid leukemia nucleus accumbens ethanol preference molecular virology viral evolution anticoagulants therapeutic efficacy regulatory network modelling genome analysis cytogenetics animal virus lymphatic disease lymphoid neoplasia ovarian hormones oogenesis opioid use disorder functional genomic landscape drug response integrative analysis kaposi ’ rhesus macaque rhadinovirus genomic analysis molecular mechanisms clinical resistance rna-seq data genomic landscape

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Cebpb/Il-1β/Tnf-α Feedback Loop Drives Drug Resistance to Venetoclax and Mdm2 Inhibitors in Monocytic Leukemia. Blood (2025)

anti-cancer agentscancer researchhematological malignanciesdrug resistancecell biologycancer cellsleukemiadrug resistance analysisimmunologypharmacologytherapeutic targetsmonocytic leukemiamdm2 inhibitorsdrug discoverymyeloid neoplasia

In Vitro Evidence for Bisphenol a as a Human Liver Carcinogen: Environmentally Relevant Doses Inhibit Cancer-Protective Esr1 Signaling in a Human Liver Cell Line. bioRxiv (Cold Spring Harbor Laboratory) (2025)

cancer lettertoxicological mechanismchemoprevention strategiesliver physiologycancer researchdrug-induced liver injurybioactive compoundsin vitro toxicologycell biologycancer cellshuman liver carcinogenbisphenol ahepatocellular carcinomabiochemistrycancer-protective esr1 signalingcancer discoveryhepatotoxicitycarcinogenesis

Metabolomic and Transcriptomic Remodeling of Bone Marrow Myeloid Cells in Response to Maternal Obesity. American Journal of Physiology-Endocrinology and Metabolism (2025)

Yem J AlharithiElysse A. PhillipsTim D. WilsonSneha P. CouvillionCarrie D. NicoraPriscila DarakjianShauna RaksheSuzanne S. FeiBrittany CountsThomas O. MetzRobert SearlesSushil KumarAlina Maloyan

maternal obesitymetabolismendocrinologymetabolic remodelingtranscriptomic remodelingmetabolomics

Effects of Repeated Alcohol Abstinence on Within-Subject Prefrontal Cortical Gene Expression in Rhesus Macaques. Advances in Drug and Alcohol Research (2024)

alcohol abstinencerhesus macaquessubstance abusealcohol (drug)substance use disordersalcohol misuseneurosciencebehavioral sciencesaddictionbehavioral neuroscienceaddictive behaviorsalcohol dependencesubstance useaddiction biology

Integrative Analysis of Drug Response and Clinical Outcome in Acute Myeloid Leukemia. Cancer Cell (2022)

Daniel BottomlyNicola LongAnna Reister SchultzStephen E. KurtzCristina E. TognonKara JohnsonMelissa AbelAnupriya AgarwalSammantha AvaylonErik BentonAurora BlucherUma BorateTheodore P. BraunJordana BrownJade BryantRussell BurkeAmy CarlosBill H. ChangHyun Jun ChoStephen ChristyCody CoblentzAaron M. CohenAmanda d’AlmeidaRachel CookAlexey DanilovKim-Hien T. DaoMichie DegninJames DibbChristopher A. EideIsabel EnglishStuart HaglerHeath HarrelsonRachel HensonHibery HoSunil K. JoshiBrian JunioAndy KaempfYoko KosakaTed LaderasMatt LawheadHyunjung LeeJessica T. LeonardChenwei LinEvan F. LindSelina Qiuying LiuPierrette LoMarc M. LoriauxSamuel LutyJulia E. MaxsonTara MaceyJacqueline MartinezJessica MinnierAndrea MonteblancoMotomi MoriQuinlan MorrowDylan NelsonJustin RamsdillAngela RofeltyAlexandra RogersKyle A. RominePeter RyabininJennifer N. SaultzDavid A. SampsonSamantha L. SavageRobert SchuffRobert SearlesRebecca L. SmithStephen E. SpurgeonTyler SweeneyRonan T. SwordsAashis ThapaKarina Thiel-KlareElie TraerJake WagnerBeth WilmotJoelle WolfGuanming WuAmy YatesHaijiao ZhangChristopher R. CogleRobert H. CollinsMichael W. DeiningerChristopher S. HouriganCraig T. JordanTara L. LinMicaela E. MartinezRachel R. PallapatiDaniel A. PollyeaAnthony D. PomicterJustin M. WattsScott J. WeirBrian J. DrukerShannon K. McWeeneyJeffrey W. Tyner

cancer genomicstumor biologymolecular diagnosticsoncologyradiation oncologycancer researchmolecular cancerdrug responsecell biologyleukemiafunctional genomicsoncogenessystems biologyintegrative analysiscancer discoveryacute myeloid leukemiamyeloid neoplasia

Effect of Chronic Ethanol Consumption in Rhesus Macaques on the Nucleus Accumbens Core Transcriptome. Addiction Biology (2021)

rhesus macaquesalcohol (drug)neurosciencechronic ethanol consumptionbehavioral neurosciencephysiologyalcohol dependencenucleus accumbensalcohol-related liver diseaseneuropsychopharmacologyaddiction biology

Identifying Rna Biomarkers and Molecular Pathways Involved in Multiple Subtypes of Uveitis. American Journal of Ophthalmology (2021)

James T. RosenbaumChristina A. HarringtonRobert P. SearlesSuzanne S. FeiAmr ZakiSruthi ArepalliMichael A. PaleyLynn M. HassmanAlbert T. VitaleChristopher D. ConradyPuthyda KeathClaire MitchellLindsey WatsonStephen R. PlanckTammy M. MartinDongseok Choi

pathway analysisocular diseasegeneticsdermatologygenomicsrna biomarkersrna biologymultiple subtypesophthalmology

Phenotypic and Gene Expression Features Associated With Variation in Chronic Ethanol Consumption in Heterogeneous Stock Collaborative Cross Mice. Genomics (2020)

gene expression featuresmetabolic pathwaysgeneticsmetabolismalcohol (drug)alcohol misusechronic ethanol consumptionphysiologyaddictive behaviorsalcohol-related liver diseaseaddiction biology

Revising the Diagnosis of Idiopathic Uveitis by Peripheral Blood Transcriptomics. American Journal of Ophthalmology (2020)

veterinary medicinedermatologyperipheral blood transcriptomicsophthalmologyidiopathic uveitisepidemiology

Rna-Seq of Human Whole Blood: Evaluation of Globin Rna Depletion on Ribo-Zero Library Method. PubMed Central (2020)

hematologymolecular diagnosticsgene expressionblood cellsnucleic acidsribo-zero library methodtranscription (biology)systems biologytranscriptomeheme homeostasisrna biologyglobin rna depletionmolecular biologyhuman whole blood

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Robert P. Searles

Oregon Health & Science University

Affiliations

Center Of Knight Cancer

OHSU School of Medicine

Center Of Portland Alcohol Research

Department of Medicine

Division Of Hematology/Medical Oncology

Institute Of Knight Cancer Insitute

Institute Of University Knight Cancer

OHSU Knight Cancer Institute

Oregon Health & Science University

NoneRobert P. Searles is currently serving as a Center Of Knight Cancer faculty at Oregon Health & Science University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Robert P. Searles

Oregon Health & Science University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Cebpb/Il-1β/Tnf-α Feedback Loop Drives Drug Resistance to Venetoclax and Mdm2 Inhibitors in Monocytic Leukemia. Blood (2025)

Metabolomic and Transcriptomic Remodeling of Bone Marrow Myeloid Cells in Response to Maternal Obesity. American Journal of Physiology-Endocrinology and Metabolism (2025)

Yem J AlharithiElysse A. PhillipsTim D. WilsonSneha P. CouvillionCarrie D. NicoraPriscila DarakjianShauna RaksheSuzanne S. FeiBrittany CountsThomas O. MetzRobert SearlesSushil KumarAlina Maloyan

maternal obesitymetabolismendocrinologymetabolic remodelingtranscriptomic remodelingmetabolomics

Effects of Repeated Alcohol Abstinence on Within-Subject Prefrontal Cortical Gene Expression in Rhesus Macaques. Advances in Drug and Alcohol Research (2024)

Integrative Analysis of Drug Response and Clinical Outcome in Acute Myeloid Leukemia. Cancer Cell (2022)

Effect of Chronic Ethanol Consumption in Rhesus Macaques on the Nucleus Accumbens Core Transcriptome. Addiction Biology (2021)

Identifying Rna Biomarkers and Molecular Pathways Involved in Multiple Subtypes of Uveitis. American Journal of Ophthalmology (2021)

pathway analysisocular diseasegeneticsdermatologygenomicsrna biomarkersrna biologymultiple subtypesophthalmology

Phenotypic and Gene Expression Features Associated With Variation in Chronic Ethanol Consumption in Heterogeneous Stock Collaborative Cross Mice. Genomics (2020)

gene expression featuresmetabolic pathwaysgeneticsmetabolismalcohol (drug)alcohol misusechronic ethanol consumptionphysiologyaddictive behaviorsalcohol-related liver diseaseaddiction biology

Revising the Diagnosis of Idiopathic Uveitis by Peripheral Blood Transcriptomics. American Journal of Ophthalmology (2020)

veterinary medicinedermatologyperipheral blood transcriptomicsophthalmologyidiopathic uveitisepidemiology

Rna-Seq of Human Whole Blood: Evaluation of Globin Rna Depletion on Ribo-Zero Library Method. PubMed Central (2020)

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10 / page