Faculty

Institution

Unit

Venue

Robert J. Barsotti

Philadelphia College of Osteopathic Medicine

Affiliations

Department Of Biomedical Sciences

NoneRobert J. Barsotti is currently serving as a Biomedical Sciences faculty at Philadelphia College of Osteopathic Medicine.

Honors

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Experiences

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Education

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Robert J. Barsotti

Philadelphia College of Osteopathic Medicine

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pharmacology physiology cardiovascular research oxidative stress circulatory physiology cardiovascular disease cardiology free radical biology reperfusion injury cardiovascular pharmacology redox biology myocardial infarction cell biology reactive oxygen species cell death cellular physiology molecular physiology redox signaling cardiovascular function antioxidants mitochondrial function bioactive compounds cell metabolism respiratory medicine applied physiology cardiovascular physiology acute myocardial infarction medicine wound healing tissue (biology) cardiac muscle hemostasis molecular medicine anatomy ocular surface keratoconus ocular tissues ocular pathology corneal dystrophy ventilation respiration (physiology) mitochondrial dynamics redox regulator mechanical ventilation keratoconus cornea mitochondrial-targeted antioxidants intensive care ophthalmology retina respiratory neurobiology ocular surface physiology muscle function cardiovascular translational research h9c2 myoblast critical care nurse photomedicine respiratory toxicology mechanical circulatory support pulmonary pharmacology human physiology laser photochemistry cellular senescence biomedical research cerebrovascular disease toxicological mechanism atrophic akt-foxo signaling myosin depletion human diaphragm disuse vitamin c doxorubicin-induced damage transmission electron tomography collagen fibrils diaphragm muscle fibers unaffected contractility activation kinetics laser photolysis skinned cardiac muscle

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract Thu083: The Different Effects Between Trimethylamine and Trimethylamine N-Oxide on H9C2 Myoblast Cells. Circulation Research (2025)

abstract thu083biochemical sciencesdna repaircellular differentiationbiochemistryredox biologytrimethylamine n-oxideh9c2 myoblast cellscell biologymolecular and cellular biologycell and molecular biology

Game Changer: Navigating Between Challenges and Hopes in Geropharmacology. Advances in pharmacology (2025)

physical anthropologygame changergame designperformance studiesgame studies

Naltrindole Attenuates Superoxide Release in Polymorphonuclear Leukocytes by a Novel Mechanism Devoid of Opioid Receptors. Physiology (2025)

pharmacological researchpharmacologyreceptorsinflammationreactive oxygen speciespolymorphonuclear leukocytesanti-inflammatorynovel mechanism devoidbiochemistryoxidative stressfree radical biologyneuropsychopharmacologyneuropharmacologymolecular pharmacologyexperimental pharmacologyopioid receptorsphysiology

Aberrant Mitochondrial Dynamics Contributes to Diaphragmatic Weakness Induced by Mechanical Ventilation. Revue des Maladies Respiratoires (2024)

M. YehyaH. DridiR. BarsottiY. LiuS. ReikenL. AzriaQ. YuanL. BahlouliR. SoniA. MarksA. LacampagneS. Matecki

neurologydiaphragmatic weaknessrespiratory medicineapplied physiologymechanical ventilationrespiratory neurobiologyventilationrespiration (physiology)disabilitydermatologyphysiology

Abstract Tu140: Evaluation of the Effects of Mitoquinone on Doxorubicin-Induced Acute Cardiac Damage. Circulation Research (2024)

pharmacological researchpharmacologyapplied pharmacologyabstract tu140medicinecardiovascular researchcardiovascular toxicitycardiovascular pharmacologypharmacotherapyclinical researchcardiovascular disease

Abstract Tu145: Exploring Naltrindole’s Hypercontracture Attenuating Effects During Myocardial Ischemia via a Novel Mechanism That Produces Cardioprotective Effects in Myocardial Ischemia/Reperfusion Injury. Circulation Research (2024)

pharmacological researchpharmacologycardiovascular physiologycardioprotective effectscardiovascular researchcardiologyreperfusion injurycardiovascular pharmacologycirculatory physiologymyocardial ischemiacardiovascular diseaseabstract tu145cardiovascular functionphysiology

Abstract We092: Naltrindole Attenuates Superoxide Release in Polymorphonuclear Leukocytes by a Novel Mechanism Devoid of Delta Opioid Receptor Antagonism Related to Reduced Intracellular Calcium Levels. Circulation Research (2024)

biochemistryoxidative stresscellular physiologymolecular pharmacologyanti-inflammatoryreceptor antagonismabstract we092pharmacological researchpharmacologyreceptorsreactive oxygen speciesredox signalingredox biologyfree radical biologyneuropsychopharmacologyexperimental pharmacologynovel mechanism devoidneuropharmacologyphysiology

Redox State of Aging Skin: A Double-Edged Sword in Wound Healing. Advances in biogerontology (2024)

redox stateageingtissue (biology)cutaneous biologyoxidative stressfree radical biologydouble-edged swordaging celllongevitydermatologywound carewound healingphysiology

Abstract 15483: Mitoquinone Pretreatment Mitigates Dox-Induced Systolic Dysfunction in Isolated Rat Hearts. Circulation (2023)

pharmacological researchpharmacologycardiovascular physiologycardiovascular functioncardiovascular researchisolated rat heartscardiologycardiovascular toxicitycardiovascular pharmacologyabstract 15483cardiovascular interventionscirculatory physiologydisease pathophysiologycardiovascular diseaseheart failurephysiology

Abstract 17814: Naltrindole Mitigates Rigor During Myocardial Ischemia by a Novel Mechanism and Shows Translational Cardioprotection in Myocardial Ischemia-Reperfusion Injury Models. Circulation (2023)

pharmacological researchpharmacologyabstract 17814critical carecardiovascular researchcardiologyreperfusion injurycardiovascular pharmacologymyocardial infarctioncardiovascular interventionscardiovascular translational researchtranslational medicinecirculatory physiologynaltrindole mitigates rigormyocardial ischemiamolecular pharmacologycardiovascular diseasephysiology

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Robert J. Barsotti

Philadelphia College of Osteopathic Medicine

Affiliations

Department Of Biomedical Sciences

NoneRobert J. Barsotti is currently serving as a Biomedical Sciences faculty at Philadelphia College of Osteopathic Medicine.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Robert J. Barsotti

Philadelphia College of Osteopathic Medicine

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract Thu083: The Different Effects Between Trimethylamine and Trimethylamine N-Oxide on H9C2 Myoblast Cells. Circulation Research (2025)

Game Changer: Navigating Between Challenges and Hopes in Geropharmacology. Advances in pharmacology (2025)

physical anthropologygame changergame designperformance studiesgame studies

Naltrindole Attenuates Superoxide Release in Polymorphonuclear Leukocytes by a Novel Mechanism Devoid of Opioid Receptors. Physiology (2025)

Aberrant Mitochondrial Dynamics Contributes to Diaphragmatic Weakness Induced by Mechanical Ventilation. Revue des Maladies Respiratoires (2024)

M. YehyaH. DridiR. BarsottiY. LiuS. ReikenL. AzriaQ. YuanL. BahlouliR. SoniA. MarksA. LacampagneS. Matecki

neurologydiaphragmatic weaknessrespiratory medicineapplied physiologymechanical ventilationrespiratory neurobiologyventilationrespiration (physiology)disabilitydermatologyphysiology

Abstract Tu140: Evaluation of the Effects of Mitoquinone on Doxorubicin-Induced Acute Cardiac Damage. Circulation Research (2024)

Redox State of Aging Skin: A Double-Edged Sword in Wound Healing. Advances in biogerontology (2024)

redox stateageingtissue (biology)cutaneous biologyoxidative stressfree radical biologydouble-edged swordaging celllongevitydermatologywound carewound healingphysiology

Abstract 15483: Mitoquinone Pretreatment Mitigates Dox-Induced Systolic Dysfunction in Isolated Rat Hearts. Circulation (2023)

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