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Robert A. Balk

Rush University

Affiliations

Department Of Pharmacology

Division Of Pulmonary And Critical Care Medicine

News & Events

Rush University

Robert A. Balk is a Senior Professor at Rush University, specializing in critical care, intensive care, respiratory medicine, and infectious diseases. His research focuses on sepsis diagnostics, including the validation of SeptiCyte RAPID for rapid blood culture positivity prediction and discrimination from non-infectious inflammation, as well as point-of-care biomarker detection. He has contributed to volatile organic compound analysis for infection detection, automated electronic medical record screening for pandemic surveillance, and guidelines on corticosteroid use in sepsis and ARDS. His work integrates epidemiology, patient safety, and public health to advance ICU outcomes.

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Robert A. Balk

Rush University

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critical care intensive care respiratory medicine sepsis patient safety emergency medicine public health medicine resuscitation hospital infections acute care acute medicine critical care clinic inflammation veterinary medicine hospital medicine clinical research thrombosis health care clinical epidemiology infection control clinical microbiology intensive care nursing community-acquired pneumonia critical emergency medicine pneumothorax septic shock respiratory infections clinical infection vascular biology pulmonary care clinical medicine clinical infectious disease cardiogenic shock pulmonary diseases infectious respiratory disease ventilation severe sepsis virus research laboratory medicine bioacoustics inflammatory markers experimental medicine community health emerging infectious diseases disease surveillance acute care surgery disease pathophysiology executive summary ventilator-associated events anesthesia general virology blood purification therapeutic efficacy health monitoring adverse events clinical immunology innate immune system pre-hospital emergency medicine diagnostic microbiology advanced lung disease biomedical technologies larynx clinical case presentation sound transmission somatic variant critical care medicine intensive care medicine united states breath sounds pneumothorax detection diagnostic applications computational study ill patients septicyte rapid acute respiratory failure

Notable Scholarly Works

Notable Federal Grants

Collaborators

866: Determining the Likelihood of Blood Culture Positivity in Sepsis in One Hour Using Septicyte Rapid. Critical Care Medicine (2026)

pathogenic bacteriapathogensinfection controlmicrobiologyinfectious diseasescritical careinfectious diseases (medical specialty)hospital infectionshealthcare-associated infectionslaboratory medicineclinical infectionplasma donationmicrobial diseasesepsisclinical laboratoryclinical microbiology

Diagnostic Performance of Point-Of-Care Immunoassay Measurements of Pancreatic Stone Protein for Sepsis Detection in Icu Patients: A Prospective, Multicenter, Biomarker-Blinded Study. Critical Care Medicine (2026)

innovative diagnosticsbioanalysisbiomarker discoverymedicinecritical carediagnostic performanceclinical chemistrybiomarkersbiomarker (medicine)pancreatic fluid collectionpancreatic stone proteindiagnosissepsis detectionsepsisclinical laboratory

1620: Septicyte Rapid Performance is Not Affected by Different Sites of Primary Infection in Sepsis. Critical Care Medicine (2025)

pathogensinfection controlmicrobiologyinfectious diseaseshospital infectionsinfectious diseases (medical specialty)healthcare-associated infectionscommunicable diseasesmicrobial diseasesepsisclinical microbiology

Automated Screening of Electronic Medical Records to Detect the Next Pandemic. American Journal of Respiratory and Critical Care Medicine (2025)

digital healthhealth information sciencehealth informaticshealth technologyclinical databasesinfectious diseasesinfectious diseases (medical specialty)electronic medical recordsepidemic intelligencecovid-19electronic health recordscommunicable diseasesdisease surveillancepublic health preparednessnext pandemicclinical dataautomated screeningepidemiology

Examination of Unique Volatile Organic Compound Signatures in Nasopharyngeal Test Swab Viral Transport Media Using an Electronic Nose. PLoS ONE (2025)

allergyelectronic nosesinfectious diseasesinfectious diseases (medical specialty)inhalation toxicologyanalytical chemistry

2024 Focused Update: Guidelines on Use of Corticosteroids in Sepsis, Acute Respiratory Distress Syndrome, and Community-Acquired Pneumonia. Critical Care Medicine (2024)

Dipayan ChaudhuriAndrea M. NeiBram RochwergRobert A. BalkKarim AsehnouneRhonda CadenaJoseph A. CarcilloRicardo CorreaKatherine DroverAnnette M. EsperHayley B. GershengornNaomi E. HammondNamita JayaprakashKusum MenonLama NazerTyler PitreZaffer A. QasimJames A. RussellAriel P. SantosAarti SarwalJoanna Spencer-SegalNejla TiloucheDjillali AnnaneStephen M. Pastores

pharmacologyrespiratory medicinecritical carecommunity-acquired pneumoniafocused updatesepsisemergency medicine

Association Between Dexmedetomidine Use and Mortality in Patients With Covid-19 Receiving Invasive Mechanical Ventilation: A U.S. National Covid Cohort Collaborative (N3C) Study. Journal of Clinical Medicine (2024)

John L. HamiltonRachel BaccileThomas J. BestPankaja DesaiAlan LandayJuan C. RojasMarkus A. WimmerRobert A. Balk

clinical effectivenessthrombosispatient safetyclinical researchintensive careclinical pharmacologycohort studiesinvasive mechanical ventilationinfectious diseasescritical carecovid-19pharmacotherapycritical emergency medicineclinical trialssars-cov-2hospital infectionsdexmedetomidine useclinical medicinepublic healthintensive care nursing

Executive Summary: Guidelines on Use of Corticosteroids in Critically Ill Patients With Sepsis, Acute Respiratory Distress Syndrome, and Community-Acquired Pneumonia Focused Update 2024. Critical Care Medicine (2024)

Dipayan ChaudhuriAndrea M. NeiBram RochwergRobert A. BalkKarim AsehnouneRhonda S. CadenaJoseph A. CarcilloRicardo CorreaKatherine DroverAnnette M. EsperHayley B. GershengornNaomi E. HammondNamita JayaprakashKusum MenonLama NazerTyler PitreZaffer A. QasimJames A. RussellAriel P. SantosAarti SarwalJoanna Spencer-SegalNejla TiloucheDjillali AnnaneStephen M. Pastores

respiratory medicineinfectious diseasescritical carecommunity-acquired pneumoniaexecutive summarysepsisemergency medicine

Major Publications in the Critical Care Pharmacotherapy Literature: 2023. Critical Care Explorations (2024)

Brian MurrayJanhavi AthaleRobert A. BalkMichael L. BehalJudah E. BrownTyler ChanasRoxana DumitruDalton C. GiffordBenjamin HohlfelderHoney M. JonesMary Beth F. MakicMichelle S. RausenAlicia J. SaccoBenjamin J. SinesPayal K. Gurnani

resuscitationcritical careintensive careclinical epidemiologypharmacotherapymajor publicationsscholarly communicationclinical researchpublic healthsepsisepidemiology

Rapid and Robust Identification of Sepsis Using Septicyte Rapid in a Heterogeneous Patient Population. Journal of Clinical Medicine (2024)

Robert BalkAnnette M. EsperGreg S. MartinRussell R. MillerBert K. LopansriJohn P. BurkeMitchell LevyRichard E. RothmanFranco R. D’AlessioVenkataramana K. SidhayeNeil R. AggarwalJared A. GreenbergMark YoderGourang PatelEmily GilbertJorge P. ParadaMajid AfsharJordan A. KempkerTom van der PollMarcus J. SchultzBrendon P. SciclunaPeter M. C. Klein KlouwenbergJanice LieblerEmily BlodgetSanthi KumarXue W. MeiKrupa NavalkarThomas D. YagerDayle SampsonJames T. KirkSilvia CermelliRoy F. DavisRichard B. Brandon

infection controlthrombosispatient safetyclinical researchrespiratory medicineintensive careclinical epidemiologysepticyte rapidemergency medicineinfectious diseasescardiologyrobust identificationdiagnostic microbiologyepidemiologyheterogeneous patient populationpathogen detectionclinical populationsclinical case presentationhospital infectionsclinical medicinesepsis

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Robert A. Balk

Rush University

Affiliations

Department Of Pharmacology

Division Of Pulmonary And Critical Care Medicine

News & Events

Rush University

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Robert A. Balk

Rush University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

866: Determining the Likelihood of Blood Culture Positivity in Sepsis in One Hour Using Septicyte Rapid. Critical Care Medicine (2026)

1620: Septicyte Rapid Performance is Not Affected by Different Sites of Primary Infection in Sepsis. Critical Care Medicine (2025)

Automated Screening of Electronic Medical Records to Detect the Next Pandemic. American Journal of Respiratory and Critical Care Medicine (2025)

Examination of Unique Volatile Organic Compound Signatures in Nasopharyngeal Test Swab Viral Transport Media Using an Electronic Nose. PLoS ONE (2025)

allergyelectronic nosesinfectious diseasesinfectious diseases (medical specialty)inhalation toxicologyanalytical chemistry

2024 Focused Update: Guidelines on Use of Corticosteroids in Sepsis, Acute Respiratory Distress Syndrome, and Community-Acquired Pneumonia. Critical Care Medicine (2024)

pharmacologyrespiratory medicinecritical carecommunity-acquired pneumoniafocused updatesepsisemergency medicine

John L. HamiltonRachel BaccileThomas J. BestPankaja DesaiAlan LandayJuan C. RojasMarkus A. WimmerRobert A. Balk

respiratory medicineinfectious diseasescritical carecommunity-acquired pneumoniaexecutive summarysepsisemergency medicine

Major Publications in the Critical Care Pharmacotherapy Literature: 2023. Critical Care Explorations (2024)

resuscitationcritical careintensive careclinical epidemiologypharmacotherapymajor publicationsscholarly communicationclinical researchpublic healthsepsisepidemiology

Rapid and Robust Identification of Sepsis Using Septicyte Rapid in a Heterogeneous Patient Population. Journal of Clinical Medicine (2024)

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