Faculty

Institution

Unit

Venue

Rik Derynck

Professor Emeritus Cell and Tissue Biology

University of California, San Francisco

Affiliations

University of California San Francisco, Research

Rik Derynck is currently serving as a University Of California San Francisco, Research Professor Emeritus Cell and Tissue Biology at University of California, San Francisco.

Honors

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Experiences

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Education

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Rik Derynck

University of California, San Francisco

Professor Emeritus Cell and Tissue Biology

You can click a keyword to filter the displayed items

molecular biology cell biology cell signaling gene expression immunology vascular biology signal transduction signaling pathways tumor biology biochemistry stem cell research receptors oncogenes membrane biology molecular cell biology transcription factors bone research biological chemistry medicinal research mammalian biology cancer biology cell regulation molecular and cellular biology cancer cells fibroblast growth factors molecular physiology leukemia cell growth cellular biology protein science host specificity host factors receptor tyrosine kinases receptor (biochemistry) molecular cancer t-regulatory cell cellular physiology inhibitory activity molecular regulation cancer growth tissue development tgf-b family growth factor intermediate host cell proliferation enzyme inhibition redox biology functional regulation gene regulation bone remodeling epithelial-mesenchymal transition protein expression transcription regulation bone repair bone homeostasis developmental genetics tgf-b signaling growth factor-a molecular basis mesenchymal stem cells angiogenesis cancer genetics protein phosphorylation host response mammary gland tgf-b receptors cancer progression tgf-b response tgf-b receptor skeletal development growth factor-b tgf-b-induced epithelial-mesenchymal transition smad signaling biological activities growth factor-b receptors bone morphogenetic protein growth factor beta cell research tgf-beta signaling developmental biology

Notable Scholarly Works

Notable Federal Grants

Collaborators

New Progress in Roles of Tgf-β Signaling Crosstalks in Cellular Functions, Immunity and Diseases. Cell Regeneration (2024)

Shuchen GuRik DerynckYe-Guang ChenXin-Hua Feng

cellular functionsimmunity (medicine)cellular immune responsesimmune responsesmolecular biologycell signalingimmunologysignaling pathwayst-regulatory cellcell biologyregeneration (biology)

Virtual Screening for Small-Molecule Pathway Regulators by Image-Profile Matching. Cell Systems (2022)

MH RohbanAM FullerC TanJT GoldsteinD SyangtanA Gutnick...

image-profile matchingvirtual screeningmolecular biologypathway analysissystems biologysystems neurosciencecell biologysmall-molecule pathway regulators

Author Correction: Guidelines and Definitions for Research on Epithelial–Mesenchymal Transition. Nature Reviews Molecular Cell Biology (2021)

Jing YangParker AntinGeert BerxCédric BlanpainThomas BrabletzMarianne BronnerKyra CampbellAmparo CanoJordi CasanovaGerhard ChristoforiShoukat DedharRik DerynckHeide L FordJonas FuxeAntonio García de HerrerosGregory J GoodallAnna-Katerina HadjantonakisRuby Y J HuangChaya KalcheimRaghu KalluriYibin KangYeesim Khew-GoodallHerbert LevineJinsong LiuGregory D LongmoreSendurai A ManiJoan MassaguéRoberto MayorDavid McClayKeith E MostovDonald F NewgreenM Angela NietoAlain PuisieuxRaymond RunyanPierre SavagnerBen StangerMarc P StemmlerYoshiko TakahashiMasatoshi TakeichiEric TheveneauJean Paul ThieryErik W ThompsonRobert A WeinbergElizabeth D WilliamsJianhua XingBinhua P ZhouGuojun Sheng

molecular cell biologymolecular biologytumor biologycell biologyepithelial-mesenchymal transitionregenerative medicineauthor correction

Epithelial Plasticity, Epithelial-Mesenchymal Transition, and the Tgf-β Family. Developmental Cell (2021)

Yoko KatsunoRik Derynck

matrix biologycancer cellscell biologyepithelial-mesenchymal transitionstem cellstissue (biology)developmental biologydevelopmental celltgf-b familytumor biologyvascular biologymorphogenesislineage plasticityfibroblast growth factorsstem cell researchcell proliferationangiogenesisepithelial plasticitycellular biologyplasticitysystems biology

Tgf ‐β as a Driver of Fibrosis: Physiological Roles and Therapeutic Opportunities. The Journal of Pathology (2021)

Erine H BudiJohanna R SchaubMartin DecarisScott TurnerRik Derynck

pathologymatrix biologycystic fibrosisfibrosisvascular biologytherapeutic opportunitiesinflammationoncologypathogenesiskey sitefibroblast growth factorsimmunologyphysiological rolesoncogenesproximate causetranscription factorstissue developmentleukemiasystems biologybone research

Tgfβ Biology in Cancer Progression and Immunotherapy. Nature Reviews Clinical Oncology (2020)

Rik DerynckShannon J. TurleyRosemary J. Akhurst

tgfb biologycolorectal cancerlung cancerliver cancercancer lettertumor heterogeneitygliomascarcinogenesisdermatologyvascular biologyneurologycancer progressionstem cell researchprostate cancerurologydisease progressionleukemiatherapeutic efficacymedicinal researchtherapeutic targets

Chronic Tgf-β Exposure Drives Stabilized Emt, Tumor Stemness, and Cancer Drug Resistance With Vulnerability to Bitopic Mtor Inhibition. Science Signaling (2019)

Yoko KatsunoDominique Stephan MeyerZiyang ZhangKevan M. ShokatRosemary J. AkhurstKohei MiyazonoRik Derynck

tumor targetingcancer drug resistancedrug resistancehost specificitycancer biologycancer researchvascular biologycatalyst activationneurologypharmacologyoncologycellular therapysignaling pathwaysurologymtor inhibitionsignal transductionenzyme inhibitioncell signalingmedicinal researchexperimental medicinetumor stemness

Emt and Cancer: More Than Meets the Eye. Developmental Cell (2019)

Rik DerynckRobert A. Weinberg

cancer biologycancer imagingdevelopmental sciencecancer researchophthalmologyoncologytissue developmentradiation oncologydevelopmental biologydevelopmental celltumor biology

Enhanced Tgf-β Signaling Contributes to the Insulin-Induced Angiogenic Responses of Endothelial Cells. iScience (2019)

Erine H. BudiOns MamaiSteven HoffmanRosemary J. AkhurstRik Derynck

endothelial cellsinsulin-induced angiogenic responsesvascular biologyangiogenesisbiomedical engineering

Integration of Tgf-β-Induced Smad Signaling in the Insulin-Induced Transcriptional Response in Endothelial Cells. Scientific Reports (2019)

Erine H. BudiSteven HoffmanShaojian GaoYing E. ZhangRik Derynck

endothelial cellsgene expressiontgf-b-induced smadsignal transductionendocrinologytranscription factorsinsulin-induced transcriptional responsemolecular biologycellular physiologycell signalingimmunologyvascular biologysignaling pathwayscell biologyfunctional regulationinsulin signaling

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Rik Derynck

Professor Emeritus Cell and Tissue Biology

University of California, San Francisco

Affiliations

University of California San Francisco, Research

Rik Derynck is currently serving as a University Of California San Francisco, Research Professor Emeritus Cell and Tissue Biology at University of California, San Francisco.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Rik Derynck

University of California, San Francisco

Professor Emeritus Cell and Tissue Biology

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

New Progress in Roles of Tgf-β Signaling Crosstalks in Cellular Functions, Immunity and Diseases. Cell Regeneration (2024)

Shuchen GuRik DerynckYe-Guang ChenXin-Hua Feng

cellular functionsimmunity (medicine)cellular immune responsesimmune responsesmolecular biologycell signalingimmunologysignaling pathwayst-regulatory cellcell biologyregeneration (biology)

Virtual Screening for Small-Molecule Pathway Regulators by Image-Profile Matching. Cell Systems (2022)

MH RohbanAM FullerC TanJT GoldsteinD SyangtanA Gutnick...

image-profile matchingvirtual screeningmolecular biologypathway analysissystems biologysystems neurosciencecell biologysmall-molecule pathway regulators

Author Correction: Guidelines and Definitions for Research on Epithelial–Mesenchymal Transition. Nature Reviews Molecular Cell Biology (2021)

molecular cell biologymolecular biologytumor biologycell biologyepithelial-mesenchymal transitionregenerative medicineauthor correction

Epithelial Plasticity, Epithelial-Mesenchymal Transition, and the Tgf-β Family. Developmental Cell (2021)

Yoko KatsunoRik Derynck

Tgf ‐β as a Driver of Fibrosis: Physiological Roles and Therapeutic Opportunities. The Journal of Pathology (2021)

Erine H BudiJohanna R SchaubMartin DecarisScott TurnerRik Derynck

Tgfβ Biology in Cancer Progression and Immunotherapy. Nature Reviews Clinical Oncology (2020)

Rik DerynckShannon J. TurleyRosemary J. Akhurst

Chronic Tgf-β Exposure Drives Stabilized Emt, Tumor Stemness, and Cancer Drug Resistance With Vulnerability to Bitopic Mtor Inhibition. Science Signaling (2019)

Yoko KatsunoDominique Stephan MeyerZiyang ZhangKevan M. ShokatRosemary J. AkhurstKohei MiyazonoRik Derynck

Emt and Cancer: More Than Meets the Eye. Developmental Cell (2019)

Rik DerynckRobert A. Weinberg

cancer biologycancer imagingdevelopmental sciencecancer researchophthalmologyoncologytissue developmentradiation oncologydevelopmental biologydevelopmental celltumor biology

Enhanced Tgf-β Signaling Contributes to the Insulin-Induced Angiogenic Responses of Endothelial Cells. iScience (2019)

Erine H. BudiOns MamaiSteven HoffmanRosemary J. AkhurstRik Derynck

endothelial cellsinsulin-induced angiogenic responsesvascular biologyangiogenesisbiomedical engineering

Integration of Tgf-β-Induced Smad Signaling in the Insulin-Induced Transcriptional Response in Endothelial Cells. Scientific Reports (2019)

Erine H. BudiSteven HoffmanShaojian GaoYing E. ZhangRik Derynck

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