Faculty

Institution

Unit

Venue

Ranmal Samarasinghe

Assistant Professor

University of California, Los Angeles

Affiliations

School of Medicine

Neurology

Ranmal Samarasinghe is currently serving as a Neurology Assistant Professor at University of California, Los Angeles.

Honors

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Experiences

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Education

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Ranmal Samarasinghe

University of California, Los Angeles

Assistant Professor

You can click a keyword to filter the displayed items

neuroscience neurology signal transduction systems neuroscience cell biology pharmacology central nervous system cell signaling neurophysiology stem cells stem cell research brain organization persistent changes glutamatergic stimulation neuroimaging human brain protein science vascular biology mammalian biology cellular physiology molecular physiology hearing research peptides intellectual disability liver physiology intercellular communication cellular neurobiology in vivo systems cell interactions molecular neurobiology anti-inflammatory cytokines cell cycle glucocorticoids dopamine protein phosphorylation neurochemistry neuroprotection brain function single-cell analysis brain circuitry brain modeling signaling pathways gene function human brain organoids epileptiform changes neural oscillations toll-like receptor anti-inflammatory cytokine dendritic cells functional purkinje cells human cerebellar organoids novel therapeutic target traumatic brain injury transient muscarinic glucocorticoid receptors lipid rafts md-phd student fellowships epilepsy neurorehabilitation neurophysiological biomarkers electrophysiology brain organoids eeg signal processing neurophysiologic intraoperative monitoring child neurology neurostimulation

Notable Scholarly Works

Notable Federal Grants

Collaborators

Functional Exploration of Epilepsy Genes in Patient-Derived Cells. Oxford University Press eBooks (2024)

Maria C. VarelaRanmal SamarasingheJack M. Parent

functional explorationepilepsy genesgene functionepilepsypatient-derived cellsgenetics

Human Cerebellar Organoids With Functional Purkinje Cells. Cell stem cell (2024)

Alexander AtamianMarcella BirteleNegar HosseiniTuan NguyenAnoothi SethAshley Del DossoSandeep PaulNeil TedeschiRyan TaylorMarcelo P. CobaRanmal SamarasingheCarlos LoisGiorgia Quadrato

human cerebellar organoidsstem cell researchcell biologystem cellsneurosciencebiologyhearing researchfunctional purkinje cells

Modeling Cortical Versus Hippocampal Network Dysfunction in a Human Brain Assembloid Model of Epilepsy and Intellectual Disability. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Colin M. McCrimmonDaniel TokerMarie PahosKevin LozanoJack J. LinJack ParentAndrew TidballJie ZhengLászló MolnárIstvan ModyBennett G. NovitchRanmal A. Samarasinghe

neurologysystems neurosciencecognitive neuroscienceneurosciencebrain organizationepilepsyintellectual disabilitybrain modelingcomputational neurosciencecentral nervous systembrain circuitry

Defining the Nature of Human Pluripotent Stem Cell-Derived Interneurons via Single-Cell Analysis. Stem Cell Reports (2021)

Thomas AllisonJustin LangermanShan SabriMarcos Otero-GarciaAndrew LundJohn HuangXiaofei WeiRanmal A. SamarasingheDamon PolioudakisIstvan ModyInma CobosBennett G. NovitchDaniel H. GeschwindKathrin PlathWilliam E. Lowry

stem cellssingle-cell analysisneurosciencestem cell research

Identification of Neural Oscillations and Epileptiform Changes in Human Brain Organoids. Nature Neuroscience (2021)

Ranmal A. SamarasingheOsvaldo A. MirandaJessie E. ButhSimon MitchellIsabella FerandoMomoko WatanabeThomas F. AllisonArinnae KurdianNamie N. FotionMichael J. GandalPeyman GolshaniKathrin PlathWilliam E. LowryJack M. ParentIstvan ModyBennett G. Novitch

neurologyneural oscillationshuman brain organoidssystems neuroscienceepileptiform changesbrain organizationneurosciencehuman brainneuroimaging

Corrigendum to “Transient Muscarinic and Glutamatergic Stimulation of Neural Stem Cells Triggers Acute and Persistent Changes in Differentiation” [Neurobiol. Dis. 70 (2014) 252–261]. Neurobiology of Disease (2014)

Ranmal A. SamarasinghePrasad S. KanuparthiJ. Timothy GreenamyreDonald B. DeFrancoRoberto DiMaio

neurologypersistent changesglutamatergic stimulationneuroscience

Transient Muscarinic and Glutamatergic Stimulation of Neural Stem Cells Triggers Acute and Persistent Changes in Differentiation. Neurobiology of Disease (2014)

Ranmal A. SamarasinghePrasad S. KanuparthiJ. Timothy GreenamyreDonald B. DeFrancoRoberto Di Maio

neurologyneurosciencetransient muscarinicglutamatergic stimulationpersistent changescentral nervous system

Cooperativity and Complementarity: Synergies in Non-Classical and Classical Glucocorticoid Signaling. Cell Cycle (2012)

Ranmal A. SamarasingheSelma F. WitchellDonald B. DeFranco

glucocorticoidscell cyclecell signalingcooperationcell biologyneurosciencepharmacologysignal transductionendocrinology

Glucocorticoid Receptors Within Lipid Rafts Activate a Mapk-Dependent, Nongenomic Signaling Pathway to Limit Gap Junction Intercellular Communication and Proliferation in Neural Stem Cells. (2011)

Ranmal SamarasingheMarcia LewisDaniela VolonteFerruccio GalbiatiDonald B DeFranco

glucocorticoid receptorssystems neuroscienceliver physiologyphysiologylipid raftscell signalingneurosciencesignaling pathwaysmembrane biologymolecular biologysignal transductiongene expression

Nongenomic Glucocorticoid Receptor Action Regulates Gap Junction Intercellular Communication and Neural Progenitor Cell Proliferation. Proceedings of the National Academy of Sciences (2011)

Ranmal Aloka SamarasingheRoberto Di MaioDaniela VolonteFerruccio GalbiatiMarcia LewisGuillermo RomeroDonald B. DeFranco

vascular biologysystems neurosciencecell interactionsphysiologyprotein sciencecellular neurobiologycell biologycellular physiologyneurosciencemolecular neurobiologymolecular physiologymembrane biologyneurophysiologyintercellular communicationin vivo systemssignal transductionmammalian biologycentral nervous system

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Ranmal Samarasinghe

Assistant Professor

University of California, Los Angeles

Affiliations

School of Medicine

Neurology

Ranmal Samarasinghe is currently serving as a Neurology Assistant Professor at University of California, Los Angeles.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Ranmal Samarasinghe

University of California, Los Angeles

Assistant Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Functional Exploration of Epilepsy Genes in Patient-Derived Cells. Oxford University Press eBooks (2024)

Maria C. VarelaRanmal SamarasingheJack M. Parent

functional explorationepilepsy genesgene functionepilepsypatient-derived cellsgenetics

Human Cerebellar Organoids With Functional Purkinje Cells. Cell stem cell (2024)

Alexander AtamianMarcella BirteleNegar HosseiniTuan NguyenAnoothi SethAshley Del DossoSandeep PaulNeil TedeschiRyan TaylorMarcelo P. CobaRanmal SamarasingheCarlos LoisGiorgia Quadrato

human cerebellar organoidsstem cell researchcell biologystem cellsneurosciencebiologyhearing researchfunctional purkinje cells

Modeling Cortical Versus Hippocampal Network Dysfunction in a Human Brain Assembloid Model of Epilepsy and Intellectual Disability. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Colin M. McCrimmonDaniel TokerMarie PahosKevin LozanoJack J. LinJack ParentAndrew TidballJie ZhengLászló MolnárIstvan ModyBennett G. NovitchRanmal A. Samarasinghe

neurologysystems neurosciencecognitive neuroscienceneurosciencebrain organizationepilepsyintellectual disabilitybrain modelingcomputational neurosciencecentral nervous systembrain circuitry

Defining the Nature of Human Pluripotent Stem Cell-Derived Interneurons via Single-Cell Analysis. Stem Cell Reports (2021)

stem cellssingle-cell analysisneurosciencestem cell research

Identification of Neural Oscillations and Epileptiform Changes in Human Brain Organoids. Nature Neuroscience (2021)

neurologyneural oscillationshuman brain organoidssystems neuroscienceepileptiform changesbrain organizationneurosciencehuman brainneuroimaging

Ranmal A. SamarasinghePrasad S. KanuparthiJ. Timothy GreenamyreDonald B. DeFrancoRoberto DiMaio

neurologypersistent changesglutamatergic stimulationneuroscience

Transient Muscarinic and Glutamatergic Stimulation of Neural Stem Cells Triggers Acute and Persistent Changes in Differentiation. Neurobiology of Disease (2014)

Ranmal A. SamarasinghePrasad S. KanuparthiJ. Timothy GreenamyreDonald B. DeFrancoRoberto Di Maio

neurologyneurosciencetransient muscarinicglutamatergic stimulationpersistent changescentral nervous system

Cooperativity and Complementarity: Synergies in Non-Classical and Classical Glucocorticoid Signaling. Cell Cycle (2012)

Ranmal A. SamarasingheSelma F. WitchellDonald B. DeFranco

glucocorticoidscell cyclecell signalingcooperationcell biologyneurosciencepharmacologysignal transductionendocrinology

Glucocorticoid Receptors Within Lipid Rafts Activate a Mapk-Dependent, Nongenomic Signaling Pathway to Limit Gap Junction Intercellular Communication and Proliferation in Neural Stem Cells. (2011)

Ranmal SamarasingheMarcia LewisDaniela VolonteFerruccio GalbiatiDonald B DeFranco

glucocorticoid receptorssystems neuroscienceliver physiologyphysiologylipid raftscell signalingneurosciencesignaling pathwaysmembrane biologymolecular biologysignal transductiongene expression

Nongenomic Glucocorticoid Receptor Action Regulates Gap Junction Intercellular Communication and Neural Progenitor Cell Proliferation. Proceedings of the National Academy of Sciences (2011)

Ranmal Aloka SamarasingheRoberto Di MaioDaniela VolonteFerruccio GalbiatiMarcia LewisGuillermo RomeroDonald B. DeFranco

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