Faculty

Institution

Unit

Venue

David W. Piston

Edward J Mallinckrodt Jr Professor and Head of Cell Biology & Physiology

Washington University in St. Louis

Affiliations

Arts & Sciences

Physics

School of Medicine

Cell Biology & Physiology

David W. Piston is currently serving as an Arts & Sciences Edward J Mallinckrodt Jr Professor and Head of Cell Biology & Physiology at Washington University In St. Louis.

Honors

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Experiences

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Education

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David W. Piston

Washington University in St. Louis

Edward J Mallinckrodt Jr Professor and Head of Cell Biology & Physiology

You can click a keyword to filter the displayed items

cell biology membrane biology physiology endocrinology microscopy molecular biology biological imaging cellular physiology pharmacology biomedical imaging molecular physiology liver physiology protein science fluorescence experimental biophysics diabetes mammalian biology tissue imaging gene expression medical biophysics metabolism endocrine research insulin signaling metabolic regulation cell physiology microscopy methods microanalysis vascular biology biological chemistry redox biology renal function optical imaging insulin secretion electron microscopy medicinal research comparative endocrinology biomedical photonics cellular biochemistry animal physiology cell metabolism circulatory physiology mitochondrial function quantitative imaging glucagon secretion cellular biology living cells fluorescent proteins two-photon excitation microscopy cancer biology gene regulation cell regulation transcription regulation molecular regulation protein secretion pancreatic b-cells biochemical sciences clinical biochemistry laser science gene function optical metrology functional regulation pancreatic islets bioluminescence mammalian physiology green fluorescent protein pancreatic islet glucose metabolism near-field optical microscopy tissue physiology lipoprotein metabolism clinical physiology protein transport fluorescence polarization microscopy background rejection glucose-stimulated insulin secretion quantitative fluorescence microscopy diabetes mellitus diabetes research islet hormone secretion

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bps2025 - Role of Complexin 2 in the Regulation of Pancreatic Islet Cell Secretion. Biophysical Journal (2025)

molecular and cellular biologysecretory pathwaycell signalingprotein secretioncell biologycellular physiologysignaling pathwaysbiochemistrydiabetes researchmolecular physiologymolecular cell biologycomplexin 2molecular gastroenterologyinsulin signalingsignal transductioncell researchcellular biochemistrycell and molecular biology

Regulation of Type 1 Diabetes via Brown Adipocyte-Secreted Proteins and the Novel Glucagon Regulator Nidogen-2. Diabetes (2025)

diabetes caremetabolic syndromemetabolismdiabetes mellitusphysiologycell signalingmetabolic regulationbiochemistrydiabetes researchdiabetes managementdiabetic medicineinsulin signalingbrown adipocyte-secreted proteinsendocrinologydiabetestype 1diabetes therapies

The Response of Mitochondrial Position to Glucose Stimulation in a Model System of the Pancreatic Beta Cell. bioRxiv (Cold Spring Harbor Laboratory) (2025)

metabolismmolecular metabolismphysiologycell biologycellular physiologymodel systemdiabetes researchcell metabolismmitochondrial positionmitochondrial functioninsulin signalingsignal transductionpancreatic beta celldiabetescell and molecular biology

An Orally Available Compound Suppresses Glucagon Hypersecretion and Normalizes Hyperglycemia in Type 1 Diabetes. JCI Insight (2024)

Farzad AsadiSubhadra C GunawardanaRoland E DolleDavid W Piston

insulin managementnutraceutical ingredientglucagon hypersecretionsymptom managementhematologydiabetes managementavailable compounddiabetic medicinepharmacologyhealth sciencesdiabetesdiabetes therapies

Dual Role of Neuroplastin in Pancreatic β Cells: Regulating Insulin Secretion and Promoting Islet Inflammation. Proceedings of the National Academy of Sciences (2024)

Rie Asada KitamuraDevynn HummelAlessandro UstioneDavid W. PistonFumihiko Urano

inflammationregulating insulin secretioncell biologyneuroinflammationcell regulationislet inflammation

High Performance Imaging and Sensing Systems for Biomedical Applications Fabricated With 2-Photon Polymerization Based Additive Manufacturing.. (2024)

Tomasz S. TkaczykJiawei LuJinyun LiuDavid Piston

additive manufacturingadvanced imagingbiomedical applicationshigh performance imagingmedical imagingbiomedical imagingbiomedical engineeringmaterials science

Insulin-Independent Regulation of Type 1 Diabetes via Brown Adipocyte-Secreted Proteins and the Novel Glucagon Regulator Nidogen-2.. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Jeongmin LeeAlessandro UstioneEmily M WilkersonRekha BalakrishnanDebbie C. ThurmondDennis GoldfarbDavid W. Piston

insulin managementcell signalinginsulin-independent regulationbiochemistrydiabetes researchmolecular biologyinsulin signalingbrown adipocyte-secreted proteinssystems biologyendocrinologydiabetesdiabetes therapies

Loss of β-Cell Katp Reduces Ca2+ Sensitivity of Insulin Secretion and Trpm5 Expression. Diabetes (2024)

Nathaniel W. YorkZihan YanAnna B. OsipovichAbbie TateSumit PatelDavid W. PistonMark A. MagnusonMaria S. RemediColin G. Nichols

insulin secretiondiabetes researchb-cell katp reducesmolecular biologyinsulin signalinggene expressiondiabetes

Measuring G Protein Activation by Spectrally Resolved Imaging Fluorescence Fluctuation Spectroscopy. Biophysical Journal (2024)

Daniel J FoustDavid W Piston

biophysicsspectroscopybiophysical chemistrybiophysical modelingfluorescence fluctuation spectroscopyfluorescence

Role of Complexin 2 in the Regulation of Hormone Secretion From the Islet of Langerhans. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Xue Wen NgMichael R. DiGruccioChen KongJeongmin LeeDavid W. Piston

physiologyhormone secretioncell signalingcellular physiologybiochemistryendocrine mechanismscytoskeletonmolecular biologynervous systemendocrinology

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David W. Piston

Edward J Mallinckrodt Jr Professor and Head of Cell Biology & Physiology

Washington University in St. Louis

Affiliations

Arts & Sciences

Physics

School of Medicine

Cell Biology & Physiology

David W. Piston is currently serving as an Arts & Sciences Edward J Mallinckrodt Jr Professor and Head of Cell Biology & Physiology at Washington University In St. Louis.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

David W. Piston

Washington University in St. Louis

Edward J Mallinckrodt Jr Professor and Head of Cell Biology & Physiology

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bps2025 - Role of Complexin 2 in the Regulation of Pancreatic Islet Cell Secretion. Biophysical Journal (2025)

Regulation of Type 1 Diabetes via Brown Adipocyte-Secreted Proteins and the Novel Glucagon Regulator Nidogen-2. Diabetes (2025)

The Response of Mitochondrial Position to Glucose Stimulation in a Model System of the Pancreatic Beta Cell. bioRxiv (Cold Spring Harbor Laboratory) (2025)

An Orally Available Compound Suppresses Glucagon Hypersecretion and Normalizes Hyperglycemia in Type 1 Diabetes. JCI Insight (2024)

Farzad AsadiSubhadra C GunawardanaRoland E DolleDavid W Piston

Dual Role of Neuroplastin in Pancreatic β Cells: Regulating Insulin Secretion and Promoting Islet Inflammation. Proceedings of the National Academy of Sciences (2024)

Rie Asada KitamuraDevynn HummelAlessandro UstioneDavid W. PistonFumihiko Urano

inflammationregulating insulin secretioncell biologyneuroinflammationcell regulationislet inflammation

High Performance Imaging and Sensing Systems for Biomedical Applications Fabricated With 2-Photon Polymerization Based Additive Manufacturing.. (2024)

Tomasz S. TkaczykJiawei LuJinyun LiuDavid Piston

additive manufacturingadvanced imagingbiomedical applicationshigh performance imagingmedical imagingbiomedical imagingbiomedical engineeringmaterials science

Insulin-Independent Regulation of Type 1 Diabetes via Brown Adipocyte-Secreted Proteins and the Novel Glucagon Regulator Nidogen-2.. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Jeongmin LeeAlessandro UstioneEmily M WilkersonRekha BalakrishnanDebbie C. ThurmondDennis GoldfarbDavid W. Piston

Loss of β-Cell Katp Reduces Ca2+ Sensitivity of Insulin Secretion and Trpm5 Expression. Diabetes (2024)

Nathaniel W. YorkZihan YanAnna B. OsipovichAbbie TateSumit PatelDavid W. PistonMark A. MagnusonMaria S. RemediColin G. Nichols

insulin secretiondiabetes researchb-cell katp reducesmolecular biologyinsulin signalinggene expressiondiabetes

Measuring G Protein Activation by Spectrally Resolved Imaging Fluorescence Fluctuation Spectroscopy. Biophysical Journal (2024)

Daniel J FoustDavid W Piston

biophysicsspectroscopybiophysical chemistrybiophysical modelingfluorescence fluctuation spectroscopyfluorescence

Role of Complexin 2 in the Regulation of Hormone Secretion From the Islet of Langerhans. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Xue Wen NgMichael R. DiGruccioChen KongJeongmin LeeDavid W. Piston

physiologyhormone secretioncell signalingcellular physiologybiochemistryendocrine mechanismscytoskeletonmolecular biologynervous systemendocrinology

1
2
3
4
5
29
10 / page

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Similar Faculty Members

Colin G. Nichols

Institution

Washington University in St. Louis

membrane transport

electrophysiology

Alvin C. Powers

Institution

Vanderbilt University

developmental biology

pancreas transplantation

Scott E. Fraser, PhD

Institution

University of Southern California

biomedical imaging

morphogenesis

Mark A. Magnuson, MD

Institution

Vanderbilt University

endocrinology

cellular plasticity

Suresh C. Tyagi

Institution

University of Louisville

health science

cardiovascular translational research

Moshe Levi

Institution

Georgetown University

metabolic disorder

nephrology

Jin Zhang

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University of California, San Diego

molecular metabolism

signaling pathway

Michelle Digman

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University of California, Irvine

biophysics

cell biology

Enrico Gratton

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University of California, Irvine

biophysics

cell biology

Krzysztof Palczewski

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biomedical informatics

retinal diseases