Faculty

Institution

Unit

Venue

Phillip Buckhaults

Professor

University of South Carolina

Affiliations

College of Pharmacy

Department of Drug Discovery and Biomedical Sciences (ddbs)

Phillip Buckhaults is currently serving as a College Of Pharmacy Professor at University of South Carolina.

Honors

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Experiences

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Education

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Phillip Buckhaults

University of South Carolina

Professor

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oncology cancer research cancer biology genetics tumor biology medicinal research cancer genomics molecular biology pharmacology health sciences cancer genetics colorectal cancer gene expression cancer care cancer treatment breast cancer molecular cancer genomics gastrointestinal oncology oncogenes human genetics leukemia cancer cells cellular therapy tumor targeting gastroenterology genome biology gene function breast oncology clinical gastroenterology biological chemistry redox biology protein science enzyme inhibition melanoma skin cancer medical genetics anti-cancer agents human breast somatic mutations molecular cell biology clinical investigation free radical biology mammalian biology genome sequencing transcription regulation protein expression cell regulation cancer prevention current views early-onset colorectal cancer dna damage response lysyl oxidase sequence analysis rna biology pancreatic cancer cytokines inflammatory markers clinical mycology drug targeting cancer growth signaling pathways protein genetics gene characterization classification method cytogenetics genomic landscapes sequence-specific transcription activators chemotherapy resistance activin signaling colorectal cancer cells frequent mutations mitf pathway tumor origin human breast cancers hedgehog pathways systems biology personalized medicine biostatistics molecular diagnostics precision medicine

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 6844: Discovery of a Novel Sialic Acid O-Acetyltransferase in Colon Tissue. Cancer Research (2024)

Bum Seok LeeAshley CookMaged ZeineldinSurojit SurLaura DobbynMaria PopoliSana KhaliliBert VogelsteinNickolas PapadopoulosShibin ZhouChetan BettegowdaPhillip BuckhaultsTatianna LarmanKathy GabrielsonKenneth W. KinzlerNicolas Wyhs

cancer genomicstumor biologyenzymescolon tissueoncologycancer researchmolecular cancercancer biologygastrointestinal oncologycancer carepharmacologycancer treatmentbiotechnologytumor targetingmolecular biologycancer discoveryhealth sciencesmedicinal research

Abstract 251: Identification of Therapeutic Vulnerabilities by Genome-Wide Crispr Knockout Library Screening of Colon Cancer Organoids. Cancer Research (2023)

Phillip J. BuckhaultsSana KhaliliCarolyn BanisterPrashanth R. GokareDave PocalykoKurtis Bachman

personalized medicinecancer genomicsgenome-wide crisprcancer researchoncologyradiation oncologybioinformaticscancer biologycrisprtherapeutic vulnerabilitiesgenomicscancer carepharmacologycancer treatmentcolon cancer organoidscancer screeninghealth sciencesmedicinal research

Abstract Lb162: A Multiplex Organoid Avatar Drug Testing Platform for Precision Medicine. Cancer Research (2023)

Shrey PatelSana KhaliliVictoria MoyEmma GraySawyer LyonsRiley BrentsCarolyn BanisterPhillip J. Buckhaults

drug testsmedicineoncologycancer researchprecision medicine

Data From Spindle Assembly Checkpoint Inhibition Can Resensitize P53-Null Stem Cells to Cancer Chemotherapy. (2023)

Changlong LiuCarolyn E. BanisterPhillip J. Buckhaults

cancer immunotherapycancer biologypharmacologytumor biologycellular therapycancer researchoncologycancer carecancer treatmentcancer genomicsanti-cancer agentsradiation oncologymolecular cancerimmunologytumor targetinggene therapymedicinal researchoncogenescancer chemotherapy

Data From Transcriptomes and Shrna Suppressors in a I Tp53 /I Allele–Specific Model of Early-Onset Colon Cancer in African Americans. (2023)

Charles C. WeigeMarc R. BirtwistleHimel MallickNengjun YiZuzana BerrongEmily CloessnerKeely DuffJosephine TidwellMegan ClendenningBrent WilkersonChristopher FarrellFred BunzHao JiMichael ShtutmanKim E. CreekCarolyn E. BanisterPhillip J. Buckhaults

cancer genomicscolorectal cancergeneticsmicroarray data analysisgene expressionhuman geneticsoncologyearly-onset colon cancercancer biologyafrican americansgenomicstranscriptomecancer geneticsmolecular biologyhealth sciencesshrna suppressors

Supplemental Figures From Biochemical and Epigenetic Insights Into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer. (2023)

Sandeep ShelarEun-Hee ShimGarrett J. BrinkleyAnirban KunduFrancesca CarobbioTyler PostonJubilee TanVishwas ParekhDaniel BensonDavid K. CrossmanPhillip J. BuckhaultsDinesh RakhejaRichard KirkmanYusuke SatoSeishi OgawaShilpa DuttaSadanandan E. VeluEthan EmberleyAlison PanJason ChenTony HuangDevin AbsherAnja BeckerConrad KunickSunil Sudarshan

leukemiapharmacologytherapeutic targetsprimary investigationcarcinogenesisoncologycancer researchcase studiespotential therapeutic targetcancer genomicsempirical case studiesbiochemistrysupplemental figuresmedicinal researchregulatory approvalepigeneticsoncogenespathologyrenal cancer

Supplementary Figures Legends From Spindle Assembly Checkpoint Inhibition Can Resensitize P53-Null Stem Cells to Cancer Chemotherapy. (2023)

Changlong LiuCarolyn E. BanisterPhillip J. Buckhaults

cancer biologytumor suppressorspharmacologytherapeutic targetstumor biologycellular therapystem cell researchcancer researchoncologyliver cancercancer carecancer treatmentcancer genomicsimmunologygene therapymedicinal researchdermatologycancer cellscancer chemotherapy

The Synthetic Food Dye, Red 40, Causes Dna Damage, Causes Colonic Inflammation, and Impacts the Microbiome in Mice. Toxicology Reports (2023)

Qi ZhangAlexander A. ChumanevichIvy NguyenAnastasiya A. ChumanevichNora SartawiJake HoganMinou KhazanQuinn HarrisBryson MasseyIoulia ChatzistamouPhillip J. BuckhaultsCarolyn E. BanisterMichael WirthJames R. HebertE. Angela MurphyLorne J. Hofseth

geneticsdna damagesynthetic food dyemicrobiomemammalian biologydna repaircolonic inflammationtoxicology

Secretory Pathway Ca2+-Atpase Spca2 Regulates Mitochondrial Respiration and Dna Damage Response Through Store-Independent Calcium Entry. Redox Biology (2022)

Monish Ram MakenaMyungjun KoAllatah X. MekileNanami SenooDonna K. DangJohn WarringtonPhillip BuckhaultsC. Conover TalbotSteven M. ClaypoolRajini Rao

enzymescell regulationsecretory pathwaystore-independent calcium entrymitochondrial respirationcell signalingredox biologydna damage responsebiochemistrymembrane biologyphysiologysignal transductiondna repairmolecular biologymolecular physiology

Tp53 Knockout in Mcf7 Breast Cancer Cells Induces Sensitivity to Fluoropyrimidine Drugs. bioRxiv (Cold Spring Harbor Laboratory) (2022)

JM WarringtonS MehtaVF MoyJR PatelC LiuAR RagoC McTigheI DelgadoCE BanisterWH GmeinerPJ Buckhaults

cancer genomicstumor biologyanti-cancer agentsgene expressiononcologycancer researchcancer biologycell biologycancer cellsoncogenespharmacologycancer treatmenttumor targetingmolecular biologybreast cancermedicinal research

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Phillip Buckhaults

Professor

University of South Carolina

Affiliations

College of Pharmacy

Department of Drug Discovery and Biomedical Sciences (ddbs)

Phillip Buckhaults is currently serving as a College Of Pharmacy Professor at University of South Carolina.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Phillip Buckhaults

University of South Carolina

Professor

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 6844: Discovery of a Novel Sialic Acid O-Acetyltransferase in Colon Tissue. Cancer Research (2024)

Abstract 251: Identification of Therapeutic Vulnerabilities by Genome-Wide Crispr Knockout Library Screening of Colon Cancer Organoids. Cancer Research (2023)

Phillip J. BuckhaultsSana KhaliliCarolyn BanisterPrashanth R. GokareDave PocalykoKurtis Bachman

Abstract Lb162: A Multiplex Organoid Avatar Drug Testing Platform for Precision Medicine. Cancer Research (2023)

Shrey PatelSana KhaliliVictoria MoyEmma GraySawyer LyonsRiley BrentsCarolyn BanisterPhillip J. Buckhaults

drug testsmedicineoncologycancer researchprecision medicine

Data From Spindle Assembly Checkpoint Inhibition Can Resensitize P53-Null Stem Cells to Cancer Chemotherapy. (2023)

Changlong LiuCarolyn E. BanisterPhillip J. Buckhaults

Data From Transcriptomes and Shrna Suppressors in a I Tp53 /I Allele–Specific Model of Early-Onset Colon Cancer in African Americans. (2023)

Supplemental Figures From Biochemical and Epigenetic Insights Into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer. (2023)

Supplementary Figures Legends From Spindle Assembly Checkpoint Inhibition Can Resensitize P53-Null Stem Cells to Cancer Chemotherapy. (2023)

Changlong LiuCarolyn E. BanisterPhillip J. Buckhaults

The Synthetic Food Dye, Red 40, Causes Dna Damage, Causes Colonic Inflammation, and Impacts the Microbiome in Mice. Toxicology Reports (2023)

geneticsdna damagesynthetic food dyemicrobiomemammalian biologydna repaircolonic inflammationtoxicology

Secretory Pathway Ca2+-Atpase Spca2 Regulates Mitochondrial Respiration and Dna Damage Response Through Store-Independent Calcium Entry. Redox Biology (2022)

Monish Ram MakenaMyungjun KoAllatah X. MekileNanami SenooDonna K. DangJohn WarringtonPhillip BuckhaultsC. Conover TalbotSteven M. ClaypoolRajini Rao

Tp53 Knockout in Mcf7 Breast Cancer Cells Induces Sensitivity to Fluoropyrimidine Drugs. bioRxiv (Cold Spring Harbor Laboratory) (2022)

JM WarringtonS MehtaVF MoyJR PatelC LiuAR RagoC McTigheI DelgadoCE BanisterWH GmeinerPJ Buckhaults

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