Faculty

Institution

Unit

Venue

Pedro Fernandez-Funez

University of Minnesota Duluth

Affiliations

Department Of Biomedical Sciences

University of Minnesota Duluth

NonePedro Fernandez-funez is currently serving as a Biomedical Sciences faculty at University of Minnesota Duluth.

Honors

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Experiences

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Education

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Pedro Fernandez-Funez

University of Minnesota Duluth

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neuroscience molecular biology insect molecular biology molecular neurodegeneration neurodegenerative diseases genetics prion diseases neurology alzheimer's disease protein science molecular neuroscience degenerative pathology protein misfolding molecular genetics gene expression neurogenetics molecular and cellular biology molecular cell biology proteomics neuroprotection prion protein molecular basis developmental genetics degenerative disease human prion protein avian biology cell death insect biochemistry developmental system cellular biochemistry brain pathology neurochemical biomarkers creutzfeldt-jakob disease drosophila models mammalian biology experimental medicine movement disorders animal science proteome research disease gene identification genomic mechanisms protein secretion protein genetics intracellular trafficking retina genetic mechanisms abnormal development drosophila model drosophila eye short ab peptides plo biology animal biotechnology gene characterization cell interactions protein phosphorylation organelle dynamics cell polarity evolutionary developmental biology gene structure experimental toxicology genetic disorders genetic basis neurochemistry aging-associated diseases animal genetics motor disorders amyloid-β neurotoxicity drosophila wing dorso-ventral compartmentalization relative expression amounts related disorders neurotoxic prion protein misfolded isoforms polyglutamine diseases genetic modifiers alzheimer brain

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bps2026 – Computational Mapping of Prion Protein Misfolding Hotspots: Insights From Entropy and Simulation. Biophysical Journal (2026)

prion proteinmolecular biophysicsbiophysicsprotein modelingprotein structurebiomolecular structuremolecular biologystructural molecular biologystructural biologycomputational biologyprotein scienceprion diseasesprotein folding

Bps2025 - Investigating Sequence Variability and Structural Determinants of Prion Protein Misfolding. Biophysical Journal (2025)

prion proteinproteomicssystems biologyprotein structurebiomolecular structuremolecular biologystructural molecular biologystructural bioinformaticsstructural biologystructural determinantsprotein sciencesequence variabilityprion diseasesbioinformatics

Conformational Dynamics as an Intrinsic Determinant of Prion Protein Misfolding and Neurotoxicity. Neural Regeneration Research (2023)

Alessandro CembranPedro Fernandez-Funez

neurologyintrinsic determinantprotein misfoldingsystems neuroscienceprion protein misfoldingneuroscienceconformational dynamics

Drosophila Models of Prion Diseases. (2023)

genetic mechanismsbiologymolecular geneticsinsect molecular biologydrosophila modelsprion diseases

Intrinsic Determinants of Prion Protein Neurotoxicity in Drosophila: From Sequence to (Dys)Function. Frontiers in Molecular Neuroscience (2023)

Alessandro CembranPedro Fernandez-Funez

neurologyprion protein neurotoxicitygeneticsmolecular neurosciencemolecular neurobiologyneuroscienceprion diseases

Mutations Affect the Conformational Plasticity of the β2-α2 Loop of Human Prion Protein. Biophysical Journal (2023)

Aliciarose JohnDavid KemperPedro Fernandez-FunezAlessandro Cembran

human prion proteinmolecular biophysicsbiophysicsconformational plasticity

Y225A Induces Long-Range Conformational Changes in Human Prion Protein That Are Protective in Drosophila. Journal of Biological Chemistry (2023)

Ryan R. MyersAliciarose JohnWeiguanliu ZhangWen-Quan ZouAlessandro CembranPedro Fernandez-Funez

protein sciencegeneticshuman prion proteinmolecular biologymolecular basisdevelopmental biologystructural biologyinsect molecular biology

New Drosophila Models to Uncover the Intrinsic and Extrinsic Factors That Mediate the Toxicity of the Human Prion Protein. Disease Models & Mechanisms (2022)

Ryan R. MyersJonatan Sanchez-GarciaDaniel C. LevingRichard G. MelvinPedro Fernandez-Funez

avian biologygeneticshuman prion proteintoxicologyinsect molecular biologyextrinsic factorsprion diseases

Effects of Mutations on Human Prion Protein Unfolding. Biophysical Journal (2020)

Aliciarose JohnRyan R. MyersPedro Fernandez-FunezAlessandro Cembran

genomicsbiophysicsmutagenesisgeneticshuman prion proteinmolecular biologymolecular basishuman geneticsprotein folding

Insight From Animals Resistant to Prion Diseases: Deciphering the Genotype – Morphotype – Phenotype Code for the Prion Protein. Frontiers in Cellular Neuroscience (2020)

Ryan MyersAlessandro CembranPedro Fernandez-Funez

prion proteinavian biologygeneticsanimal sciencemolecular geneticsmolecular basisanimal geneticsprion diseases

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Pedro Fernandez-Funez

University of Minnesota Duluth

Affiliations

Department Of Biomedical Sciences

University of Minnesota Duluth

NonePedro Fernandez-funez is currently serving as a Biomedical Sciences faculty at University of Minnesota Duluth.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Pedro Fernandez-Funez

University of Minnesota Duluth

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bps2026 – Computational Mapping of Prion Protein Misfolding Hotspots: Insights From Entropy and Simulation. Biophysical Journal (2026)

Bps2025 - Investigating Sequence Variability and Structural Determinants of Prion Protein Misfolding. Biophysical Journal (2025)

Conformational Dynamics as an Intrinsic Determinant of Prion Protein Misfolding and Neurotoxicity. Neural Regeneration Research (2023)

Alessandro CembranPedro Fernandez-Funez

neurologyintrinsic determinantprotein misfoldingsystems neuroscienceprion protein misfoldingneuroscienceconformational dynamics

Drosophila Models of Prion Diseases. (2023)

genetic mechanismsbiologymolecular geneticsinsect molecular biologydrosophila modelsprion diseases

Intrinsic Determinants of Prion Protein Neurotoxicity in Drosophila: From Sequence to (Dys)Function. Frontiers in Molecular Neuroscience (2023)

Alessandro CembranPedro Fernandez-Funez

neurologyprion protein neurotoxicitygeneticsmolecular neurosciencemolecular neurobiologyneuroscienceprion diseases

Mutations Affect the Conformational Plasticity of the β2-α2 Loop of Human Prion Protein. Biophysical Journal (2023)

Aliciarose JohnDavid KemperPedro Fernandez-FunezAlessandro Cembran

human prion proteinmolecular biophysicsbiophysicsconformational plasticity

Y225A Induces Long-Range Conformational Changes in Human Prion Protein That Are Protective in Drosophila. Journal of Biological Chemistry (2023)

Ryan R. MyersAliciarose JohnWeiguanliu ZhangWen-Quan ZouAlessandro CembranPedro Fernandez-Funez

protein sciencegeneticshuman prion proteinmolecular biologymolecular basisdevelopmental biologystructural biologyinsect molecular biology

New Drosophila Models to Uncover the Intrinsic and Extrinsic Factors That Mediate the Toxicity of the Human Prion Protein. Disease Models & Mechanisms (2022)

Ryan R. MyersJonatan Sanchez-GarciaDaniel C. LevingRichard G. MelvinPedro Fernandez-Funez

avian biologygeneticshuman prion proteintoxicologyinsect molecular biologyextrinsic factorsprion diseases

Effects of Mutations on Human Prion Protein Unfolding. Biophysical Journal (2020)

Aliciarose JohnRyan R. MyersPedro Fernandez-FunezAlessandro Cembran

genomicsbiophysicsmutagenesisgeneticshuman prion proteinmolecular biologymolecular basishuman geneticsprotein folding

Insight From Animals Resistant to Prion Diseases: Deciphering the Genotype – Morphotype – Phenotype Code for the Prion Protein. Frontiers in Cellular Neuroscience (2020)

Ryan MyersAlessandro CembranPedro Fernandez-Funez

prion proteinavian biologygeneticsanimal sciencemolecular geneticsmolecular basisanimal geneticsprion diseases

1
2
3
4
5
6
10 / page