Faculty

Institution

Unit

Venue

Paul Lin

The University of Texas MD Anderson Cancer Center

Affiliations

Department Of Breast Surgical Oncology

Division Of Cancer Medicine

Department Of Stem Cell Transplantation

Institute for Cell Therapy Discovery & Innovation

The University of Texas MD Anderson Cancer Center

Paul Lin is a Senior Professor at The University of Texas MD Anderson Cancer Center. His research integrates hematology, oncology, and immunology, focusing on cellular therapy, clinical bone marrow transplantation, and hematological malignancies. His latest work centers on engineering CAR-NK cells to overcome immune evasion in acute myeloid leukemia and multiple myeloma, including targeting CD226 and CD70 pathways, and identifying regulatory checkpoints like CREM via genome-wide CRISPR screens. He also investigates lenalidomide maintenance and transplant outcomes for multiple myeloma patients with suboptimal responses or prior solid tumors. His publications appear in Nature, Cancer Cell, and Blood Cancer Discovery.

Honors

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Experiences

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Paul Lin

The University of Texas MD Anderson Cancer Center

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oncology hematology cellular therapy immunology medicine cell transplantation clinical transplantation bone marrow transplantation cell therapy hematological malignancies medicinal research cancer treatment stem cell transplantation multiple myeloma cancer research organ transplantation dermatology cancer immunotherapy regenerative medicine tumor biology transplantation medicine pharmacology cancer care cancer biology outcomes research leukemia cancer cells tumor targeting cellular immune responses stem-cell therapy cell death stem cell research cancer management adaptive immune system novel therapies transplant surgery multiple myeloma patients liver transplantation anti-cancer agents cord blood cancer genetics blood cells pharmacotherapy cell research oncogenes immune checkpoint inhibitors clinical immunology surgical oncology cellular physiology skin cancer innate immune system biological therapies cell replacement therapies immunohaematology tumor suppressors cancer immunosurveillance acute myeloid leukemia intraoperative consultation gynecological surgery science studies melanoma tumor heterogeneity therapeutic efficacy clinical efficacy braf-mutant melanoma surgical staging current status car-nk cell therapy cytokine engineering long-term outcome limited progression metabolic fitness gmp-compliant universal antigen antitumor activity regulatory checkpoint nk cells

Notable Scholarly Works

Notable Federal Grants

Collaborators

Lenalidomide Maintenance After Delayed or Salvage Autologous Stem Cell Transplantation. Leukemia & lymphoma/Leukemia and lymphoma (2026)

cell therapysurgerylenalidomide maintenancestem cellscell transplantationhematologybone marrow transplantationmedicinestem cell transplantation

Cd70-Targeting Car Nk Cells Overcome Bcma Downregulation and Improve Survival in High-Risk Multiple Myeloma Models. Blood Cancer Discovery (2025)

oncogenescancer immunotherapyimmunologycell biologycell transplantationimmunotherapycellular therapyhematological malignanciesimmune responsesimmunity (medicine)cancer cellsimmune checkpoint inhibitorsimprove survival

Crem is a Regulatory Checkpoint of Car and Il-15 Signalling in Nk Cells. Nature (2025)

Hind RafeiRafet BasarSunil AcharyaYu-Sung HsuPinghua LiuDeqiang ZhangToszka BohnQingnan LiangVakul MohantyRanjan UpadhyayPing LiPravin PhadatareMerve DedeDonghai XiongHuihui FanCorry Mathew JonesSebastian KunzMay DaherAna Karen Nunez CortesMayra ShanleyBin LiuSadie Mae MoseleyChenyu ZhangDexing FangPinaki BanerjeeNadima UpretyYe LiRejeena ShresthaXinhai WanHong ShenVernikka WoodsApril Lamour GilbertSeema RawalJinzhuang DouYukun TanJeong-Min ParkFrancia Reyes SilvaAlexander BiederstädtMecit KaplanXin Ru JiangInci BiederstädtBijender KumarSilvia TibertiMadison MooreJingling JinRyan Z YangLuis Muniz-FelicianoSamuel RosemorePaul LinGary M DeyterNatalie Wall FowlkesAbhinav K JainDavid MarinAnirban MaitraKen ChenTobias BoppElizabeth J ShpallKatayoun Rezvani

pathologyliver physiologystem cell researchgliomasdermatologypharmacologytherapeutic targetsnk cellsvascular biologytumor biologynovel therapiesgene expressionmedicinal researchcancer biologytumor heterogeneityinflammationviral persistenceleukemiatherapeutic efficacyregulatory checkpoint

Daratumumab-Based Second Line Therapy Improves Outcomes After Vrd Induction, Upfront Autologous Transplant and Lenalidomide Maintenance. Transplantation and Cellular Therapy (2025)

vrd inductionlenalidomide maintenanceimmunologycell transplantationnovel therapiesimmunotherapybone marrow transplantationimmune checkpoint inhibitorsmedicineclinical transplantationclinical trialsoncologyupfront autologous transplant

Genome-Wide Crispr Screens Identify Critical Targets to Enhance Car-Nk Cell Antitumor Potency. Cancer Cell (2025)

gene editinggenome editinggenome-wide crispr screenscancer immunotherapycrisprimmunologycell biologynovel therapiescritical targetscellular therapycancer cells

Optimizing Essential, Complex Hematologic Care for Patients Living With Disabilities. Blood (2025)

medical systemshealth carecare deliverypatient managementintegrated caredisabilitycomplex hematologic carehematologymultidisciplinary caremedicineinternal medicineemergency medicineintensive care

Outcomes of Multiple Myeloma Patients With Prior Solid Tumors Undergoing Autologous Transplantation. Transplantation and Cellular Therapy (2025)

prior solid tumorsradiation oncologyautologous transplantationsurgeryorgan transplantationhematological malignancieshematologybone marrow transplantationclinical transplantationgraft survivalmultiple myeloma patientscancer careoncologytransplantation medicine

Outcomes of Patients With Igd Multiple Myeloma Undergoing Autologous Hematopoietic Stem Cell Transplant. Transplantation and Cellular Therapy (2025)

radiation oncologycell transplantationhematological malignancieshematologybone marrow transplantationstem cell transplantationoncology

Outcomes of Patients With Multiple Myeloma Undergoing Autologous Transplant With Suboptimal Pretransplant Response. British Journal of Haematology (2025)

autologous transplantorgan transplantationimmunologycell transplantationhematological malignancieshematologybone marrow transplantationmedicineclinical transplantationsuboptimal pretransplant responsegraft survivaloncologymultiple myelomatransplantation medicine

Outcomes of Patients With Multiple Myeloma With Deletion 1P Following Autologous Stem Cell Transplant. Transplantation and Cellular Therapy (2025)

radiation oncologydeletion 1pcell transplantationhematological malignancieshematologybone marrow transplantationstem cell transplantationoncologymultiple myeloma

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Paul Lin

The University of Texas MD Anderson Cancer Center

Affiliations

Department Of Breast Surgical Oncology

Division Of Cancer Medicine

Department Of Stem Cell Transplantation

Institute for Cell Therapy Discovery & Innovation

The University of Texas MD Anderson Cancer Center

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Paul Lin

The University of Texas MD Anderson Cancer Center

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Lenalidomide Maintenance After Delayed or Salvage Autologous Stem Cell Transplantation. Leukemia & lymphoma/Leukemia and lymphoma (2026)

cell therapysurgerylenalidomide maintenancestem cellscell transplantationhematologybone marrow transplantationmedicinestem cell transplantation

Cd70-Targeting Car Nk Cells Overcome Bcma Downregulation and Improve Survival in High-Risk Multiple Myeloma Models. Blood Cancer Discovery (2025)

Crem is a Regulatory Checkpoint of Car and Il-15 Signalling in Nk Cells. Nature (2025)

Daratumumab-Based Second Line Therapy Improves Outcomes After Vrd Induction, Upfront Autologous Transplant and Lenalidomide Maintenance. Transplantation and Cellular Therapy (2025)

Genome-Wide Crispr Screens Identify Critical Targets to Enhance Car-Nk Cell Antitumor Potency. Cancer Cell (2025)

gene editinggenome editinggenome-wide crispr screenscancer immunotherapycrisprimmunologycell biologynovel therapiescritical targetscellular therapycancer cells

Optimizing Essential, Complex Hematologic Care for Patients Living With Disabilities. Blood (2025)

medical systemshealth carecare deliverypatient managementintegrated caredisabilitycomplex hematologic carehematologymultidisciplinary caremedicineinternal medicineemergency medicineintensive care

Outcomes of Multiple Myeloma Patients With Prior Solid Tumors Undergoing Autologous Transplantation. Transplantation and Cellular Therapy (2025)

Outcomes of Patients With Igd Multiple Myeloma Undergoing Autologous Hematopoietic Stem Cell Transplant. Transplantation and Cellular Therapy (2025)

radiation oncologycell transplantationhematological malignancieshematologybone marrow transplantationstem cell transplantationoncology

Outcomes of Patients With Multiple Myeloma Undergoing Autologous Transplant With Suboptimal Pretransplant Response. British Journal of Haematology (2025)

Outcomes of Patients With Multiple Myeloma With Deletion 1P Following Autologous Stem Cell Transplant. Transplantation and Cellular Therapy (2025)

radiation oncologydeletion 1pcell transplantationhematological malignancieshematologybone marrow transplantationstem cell transplantationoncologymultiple myeloma

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