Faculty

Institution

Unit

Venue

Paul E Phillips

Upstate Medical University

Affiliations

Norton College of Medicine

Department Of Medicine

Division Of Rheumatology

Department Of Rheumatology

Department Of Medicine

Division Of Rheumatology

Upstate Medical University

NonePaul E Phillips is currently serving as a Medicine faculty at Upstate Medical University.

Honors

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Experiences

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Education

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Paul E Phillips

Upstate Medical University

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immunology rheumatology medicine systemic lupus erythematosus pharmacology hematology clinical immunology health sciences virology immune responses clinical rheumatology cell signaling immunotherapy medicinal research experimental medicine cytokines signal transduction t-regulatory cell rheumatoid arthritis cellular therapy cellular immune responses mechanistic target mammalian biology pharmacotherapy enzyme inhibition internal medicine redox signaling mitochondrial function immunopathology vasculitis virus-host interactions immunological biomarkers mammalian target antiphospholipid syndrome disease activity cell death pharmacological research clinical investigation arthritis virus research medical virology diabetes therapies clinical microbiology inhibitory activity immunosuppressive therapy immunomodulation connective tissue disease biomedical research experimental pharmacology host factors experimental biology experimental therapeutics molecular immunology mitochondrial biogenesis immunogenetics haplotype determination viral pathogenesis antibody engineering signaling pathways endocrine diseases endocrine research celiac disease diabetes mellitus medical microbiology medical genetics placebo-controlled trial mitochondrial hyperpolarization atp depletion conventional medications n-acetylcysteine-responsive accumulation comprehensive metabolome analyses myxovirus antibody necrotic death oligodendrocyte-specific expression antibody reactivity overlap syndromes

Notable Scholarly Works

Notable Federal Grants

Collaborators

1203 Blockade of the Mechanistic Target of Rapamycin Elicits Rapid and Lasting Improvement of Disease Activity Through Restraining Pro-Inflammatory T Cell Lineage Specification in Patients With Active Sle. (2022)

Zhi-Wei LaiRyan KellyThomas WinansIvan MarchenaAshwini ShadakshariJulie YuMaha DawoodRicardo GarciaHajra TilyLisa FrancisStephen V FaraonePaul E PhillipsAndras Perl

chronic inflammationmedicinelasting improvementcell signalingdisease activitypharmacologytherapeutic targetscellular therapyrapamycin elicitsimmunotherapyclinical immunologyimmune responsesclinical transplantationimmunologyanti-inflammatorycytokinesactive slemedicinal researchmechanistic targetinflammationdrug targetingexperimental medicineenzyme inhibition

Sirolimus for Systemic Lupus Erythematosus – Authors' Reply. The Lancet (2018)

Andras PerlZhi-Wei LaiRyan KellyStephen V FaraonePaul E Phillips

immunologymedicineautoimmune diseasesrheumatology

Sirolimus in Patients With Clinically Active Systemic Lupus Erythematosus Resistant to, or Intolerant of, Conventional Medications: A Single-Arm, Open-Label, Phase 1/2 Trial. The Lancet (2018)

Zhi-Wei LaiRyan KellyThomas WinansIvan MarchenaAshwini ShadakshariJulie YuMaha DawoodRicardo GarciaHajra TilyLisa FrancisStephen V FaraonePaul E PhillipsAndras Perl

medicinepharmacologyrheumatologyconventional medicationsclinical trials

Induction of Systemic Lupus Erythematosus With Tumor Necrosis Factor. (2017)

Paul E. PhillipsAndras PerlEkaterina SoforoManfred BaumgartnerLisa FrancisFatme Allam

hematologytumor necrosis factorautoimmune diseasesimmunologypharmacologysystemic lupus erythematosusneurologyrheumatology

AI-29 Metabolome Checkpoints of Mtor Activation and Clinical Responsiveness in Sle. (2016)

Andras PerlZhiwei LaiZachary OaksJohn AsaraRobert HanczkoRyan KellyPaul Phillips

clinical responsivenessimmunologypharmacologymtor activationmetabolomics

Comprehensive Metabolome Analyses Reveal N-Acetylcysteine-Responsive Accumulation of Kynurenine in Systemic Lupus Erythematosus: Implications for Activation of the Mechanistic Target of Rapamycin. Metabolomics (2015)

Andras PerlRobert HanczkoZhi-Wei LaiZachary OaksRyan KellyRebecca BorsukJohn M. AsaraPaul E. Phillips

mechanistic targetdrug metabolismcomprehensive metabolome analysesn-acetylcysteine-responsive accumulationimmunologypharmacologybiochemistrysystemic lupus erythematosusmetabolomics

Mtor Activation Triggers Proinflammatory Expansion of Il-4-Producing and Necrosis-Prone Double-Negative T Cells, Precedes Flares, and Serves as Target for Treatment in Patients With Systemic Lupus Erythematosus. Arthritis Research & Therapy (2014)

Zhi-Wei LaiRebecca BorsukAshwini ShadakshariJianghong YuMaha DawoodRicardo GarciaLisa FrancisHajra TilyAdam BartosStephen V FaraonePaul PhillipsAndras Perl

chronic inflammationmedicinepharmacologyrheumatologypain researchimmunotherapyclinical immunologycellular immune responsesimmune responsesimmunologysystemic lupus erythematosusinflammatory markerscytokinesmedicinal researchhematologyinflammationpain medicineclinical rheumatologyexperimental medicine

Mechanistic Target of Rapamycin Activation Triggers Il-4 Production and Necrotic Death of Double-Negative T Cells in Patients With Systemic Lupus Erythematosus. The Journal of Immunology (2013)

Zhi-Wei LaiRebecca BorsukAshwini ShadakshariJianghong YuMaha DawoodRicardo GarciaLisa FrancisHajra TilyAdam BartosStephen V. FaraonePaul PhillipsAndras Perl

mechanistic targetimmune responsest-regulatory cellnecrotic deathdermatologycell signalingclinical immunologyimmunologypharmacologyimmunity (medicine)systemic lupus erythematosussignal transductioncytokinesimmunopathologyrheumatologycell deathcellular immune responses

N ‐Acetylcysteine Reduces Disease Activity by Blocking Mammalian Target of Rapamycin in T Cells From Systemic Lupus Erythematosus Patients: A Randomized, Double‐Blind, Placebo‐Controlled Trial. Arthritis & Rheumatism (2012)

Zhi‐Wei LaiRobert HanczkoEduardo BonillaTiffany N. CazaBrandon ClairAdam BartosGabriella MiklossyJohn JimahEdward DohertyHajra TilyLisa FrancisRicardo GarciaMaha DawoodJianghong YuIrene RamosIoana ComanStephen V. FaraonePaul E. PhillipsAndras Perl

immunomodulationmammalian targetmedicinet-regulatory celldisease activitypharmacologymammalian biologyinhibitory activityrheumatologyimmunosuppressive therapyimmunotherapyclinical immunologyclinical trialsimmunologymedicinal researchplacebo-controlled trialclinical rheumatologyexperimental medicineclinical researchpharmacotherapy

Expansion of Cd3+/Cd4+/Cd25+/Foxp3+ T Cells in Rapamycin-Treated Lupus Patients (143.52). The Journal of Immunology (2010)

Andras PerlZhi-Wei LaiTiffany TelaricoAdam BartosGabriella MiklossyRobert HanczkoLisa FrancisHajra TilyIrene RamosRicardo GarciaPaul PhillipsJohn JimahEdward Doherty

hematologyimmune responsesmedicinecellular therapycell therapyt-regulatory celladaptive immune systemimmunotherapyclinical immunologyimmunologypharmacologyrheumatologycellular immune responsesrapamycin-treated lupus patients

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Paul E Phillips

Upstate Medical University

Affiliations

Norton College of Medicine

Department Of Medicine

Division Of Rheumatology

Department Of Rheumatology

Department Of Medicine

Division Of Rheumatology

Upstate Medical University

NonePaul E Phillips is currently serving as a Medicine faculty at Upstate Medical University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Paul E Phillips

Upstate Medical University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Zhi-Wei LaiRyan KellyThomas WinansIvan MarchenaAshwini ShadakshariJulie YuMaha DawoodRicardo GarciaHajra TilyLisa FrancisStephen V FaraonePaul E PhillipsAndras Perl

Sirolimus for Systemic Lupus Erythematosus – Authors' Reply. The Lancet (2018)

Andras PerlZhi-Wei LaiRyan KellyStephen V FaraonePaul E Phillips

immunologymedicineautoimmune diseasesrheumatology

Sirolimus in Patients With Clinically Active Systemic Lupus Erythematosus Resistant to, or Intolerant of, Conventional Medications: A Single-Arm, Open-Label, Phase 1/2 Trial. The Lancet (2018)

Zhi-Wei LaiRyan KellyThomas WinansIvan MarchenaAshwini ShadakshariJulie YuMaha DawoodRicardo GarciaHajra TilyLisa FrancisStephen V FaraonePaul E PhillipsAndras Perl

medicinepharmacologyrheumatologyconventional medicationsclinical trials

Induction of Systemic Lupus Erythematosus With Tumor Necrosis Factor. (2017)

Paul E. PhillipsAndras PerlEkaterina SoforoManfred BaumgartnerLisa FrancisFatme Allam

hematologytumor necrosis factorautoimmune diseasesimmunologypharmacologysystemic lupus erythematosusneurologyrheumatology

AI-29 Metabolome Checkpoints of Mtor Activation and Clinical Responsiveness in Sle. (2016)

Andras PerlZhiwei LaiZachary OaksJohn AsaraRobert HanczkoRyan KellyPaul Phillips

clinical responsivenessimmunologypharmacologymtor activationmetabolomics

Andras PerlRobert HanczkoZhi-Wei LaiZachary OaksRyan KellyRebecca BorsukJohn M. AsaraPaul E. Phillips

mechanistic targetdrug metabolismcomprehensive metabolome analysesn-acetylcysteine-responsive accumulationimmunologypharmacologybiochemistrysystemic lupus erythematosusmetabolomics

Zhi-Wei LaiRebecca BorsukAshwini ShadakshariJianghong YuMaha DawoodRicardo GarciaLisa FrancisHajra TilyAdam BartosStephen V FaraonePaul PhillipsAndras Perl

Mechanistic Target of Rapamycin Activation Triggers Il-4 Production and Necrotic Death of Double-Negative T Cells in Patients With Systemic Lupus Erythematosus. The Journal of Immunology (2013)

Zhi-Wei LaiRebecca BorsukAshwini ShadakshariJianghong YuMaha DawoodRicardo GarciaLisa FrancisHajra TilyAdam BartosStephen V. FaraonePaul PhillipsAndras Perl

Expansion of Cd3+/Cd4+/Cd25+/Foxp3+ T Cells in Rapamycin-Treated Lupus Patients (143.52). The Journal of Immunology (2010)

Andras PerlZhi-Wei LaiTiffany TelaricoAdam BartosGabriella MiklossyRobert HanczkoLisa FrancisHajra TilyIrene RamosRicardo GarciaPaul PhillipsJohn JimahEdward Doherty

1
2
3
4
5
10 / page