Faculty

Institution

Unit

Venue

Patricia Kane

Distinguished Teaching Professor of Biochemistry and Molecular Biology

Upstate Medical University

Affiliations

Norton College of Medicine

Department Of Anesthesiology

Department Of Neuroscience And Physiology

Institute Of Suny Upstate Cancer Research

Department Of Anesthesiology

Norton College Of Medicine

Upstate Medical University

Patricia Kane is currently serving as an Anesthesiology Distinguished Teaching Professor of Biochemistry and Molecular Biology at Upstate Medical University.

Honors

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Experiences

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Education

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Patricia Kane

Upstate Medical University

Distinguished Teaching Professor of Biochemistry and Molecular Biology

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biochemistry molecular biology enzymes yeast molecular and cellular biology biological chemistry cellular enzymology protein science cellular biochemistry molecular cell biology structural molecular biology cell biology cell and molecular biology membrane proteins membrane biology bioenergetics signal transduction structure-function enzyme kinetics molecular motors molecular metabolism biophysics protein structure fungal genetics biomolecular structure cell metabolism cellular physiology membrane transport fungal cell biology protein phosphorylation enzyme inhibition redox biology biochemical sciences molecular physiology biomolecular interactions immunoglobulin e secretory pathway proteinlipid interaction protein biosynthesis biological macromolecules molecular research protein assembly enzyme catalysis receptor (biochemistry) protein function yeast vacuolar h+-atpase cell physiology biochemical interaction molecular regulation molecular immunology cell surface organelle dynamics cellular biology functional modification redox signaling biochemical genetics mutagenesis molecular pathways cell regulation immunochemistry organelle acidification rave complex yeast v-atpase v-atpase activity saccharomyces cerevisiae vacuolar h+-atpase mutational analysis ige-receptor complexes omics integration pharmacogenomics pathway analysis target pathways yeast lysosome-like vacuole cytosolic ph homeostasis stable assembly atpase activity lipid pi fungal ecology biotechnology ima fungus biosystems microbial cell factory computational biology molecular informatics proteomics proteome research plo biology transcription factors metabolic engineering nucleic acids bioinformatics biosynthesis quantitative biology omics functional genomics transcription (biology) biology fungus chromatin biotechnology advance theoretical biology synthetic biology biological engineering medical mycology gene expression systems biology genetics biomolecular engineering molecular plant-microbe interactions molecular genetics metabolomics microbiology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Early Lipid-Mediated Responses to Hyperosmotic Stress at the Yeast Vacuole. Molecular Biology of the Cell (2026)

lipid sciencefungal cell biologymolecular metabolismmolecular and cellular biologyhyperosmotic stressyeastbiochemistryphysiologylipidscell metabolismcellular biochemistry

Mitochondrial Protein Import Stress Causes Lysosomal Damage and Progressive Tissue Atrophy. EMBO Reports (2026)

lysosomal damagemitochondrial functionneurodegenerative diseasesmuscular dystrophiescell biologymolecular cell biologyprogressive tissue atrophyautophagymitochondrial dynamicsmolecular neurodegenerationmolecular biologycell metabolism

Source Data for Saravanan and Kane," Early Responses to Hyperosmotic Stress at the Yeast Vacuole". Open MIND (2026)

metabolic pathwaysgene expressionmolecular and cellular biologymolecular geneticsmolecular metabolismyeasthyperosmotic stresssource datamolecular cell biologyphysiologycell and molecular biologymolecular biologystress (biology)cellular regulatory mechanismcellular biochemistry

Abstract 2474 Rogdi is the Homolog of Yeast Rav2 and a Novel Rabconnectin-3 Subunit. Journal of Biological Chemistry (2025)

molecular geneticsmolecular and cellular biologynovel rabconnectin-3 subunityeastfungal geneticssecretory pathwaymolecular cell biologyprotein scienceyeast rav2structural molecular biologyprotein structurebiomolecular structurebiochemistryabstract 2474molecular biologyfungal cell biologystructural biology

Abstract 2792 Metabolic Modulation of V-Atpase Proton Pump in the Aging Lysosome. Journal of Biological Chemistry (2025)

aging cellmetabolic modulationmolecular metabolismv-atpase proton pumpmembrane proteinsbioenergeticsbiochemistrymembrane biologyabstract 2792cellular senescencemolecular biologycell metabolismbiogerontology

Bps2025 - Structure of Yeast Rave Bound to a Partial V1 Complex. Biophysical Journal (2025)

yeastcrystallographyprotein structurephysicsmolecular biologyyeast rave boundpartial v1 complexstructural biology

Early Responses to Hyperosmotic Stress at the Yeast Vacuole. bioRxiv (Cold Spring Harbor Laboratory) (2025)

gene expressionmolecular and cellular biologyhyperosmotic stressyeastmolecular cell biologyfungal physiologyphysiologymolecular biologystress (biology)cellular physiologycellular biochemistry

Mdm38/Letm1 Couples Ion Homeostasis and Proteostatic Mechanisms in the Inner Mitochondrial Membrane. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Iryna BohovychGabriella Menezes da SilvaSaieeda Fabia AliEmma J. BergmeyerEdward M. GermanyAdarsh MayankJames A. WohlschlegelJason C. CaslerMuhammad Arifur RahmanTaras Y. NazarkoMaureen TarsioTakuya ShiotaLaura L. LacknerSteven M. ClaypoolPatricia M. KaneAntoni BarrientosOleh Khalimonchuk

biophysicsmitochondrial functionproteostatic mechanismsbiochemistrymembrane biologymolecular biologyinner mitochondrial membrane

The Rogdi Protein Mutated in Kohlschutter–Tonz Syndrome is a Novel Subunit of the Rabconnectin-3 Complex Implicated in V-Atpase Assembly. Journal of Biological Chemistry (2025)

rogdi proteinmolecular geneticsmolecular and cellular biologycell biologymolecular cell biologyprotein sciencev-atpase assemblykohlschutter–tonz syndromeprotein geneticsgenetic disorderscell and molecular biologymolecular biologyprotein functionmolecular researchmolecular medicinecellular biochemistry

V‐Atpase Disassembly at the Yeast Lysosome‐Like Vacuole is a Phenotypic Driver of Lysosome Dysfunction in Replicative Aging. Aging Cell (2025)

aging cellmolecular and cellular biologyyeastcellular enzymologyreplicative agingmolecular cell biologyprotein scienceautophagybiochemistrycell and molecular biologymolecular biologyorganelle dynamicsv‐atpase disassemblylysosome dysfunction

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Patricia Kane

Distinguished Teaching Professor of Biochemistry and Molecular Biology

Upstate Medical University

Affiliations

Norton College of Medicine

Department Of Anesthesiology

Department Of Neuroscience And Physiology

Institute Of Suny Upstate Cancer Research

Department Of Anesthesiology

Norton College Of Medicine

Upstate Medical University

Patricia Kane is currently serving as an Anesthesiology Distinguished Teaching Professor of Biochemistry and Molecular Biology at Upstate Medical University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Patricia Kane

Upstate Medical University

Distinguished Teaching Professor of Biochemistry and Molecular Biology

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Early Lipid-Mediated Responses to Hyperosmotic Stress at the Yeast Vacuole. Molecular Biology of the Cell (2026)

lipid sciencefungal cell biologymolecular metabolismmolecular and cellular biologyhyperosmotic stressyeastbiochemistryphysiologylipidscell metabolismcellular biochemistry

Mitochondrial Protein Import Stress Causes Lysosomal Damage and Progressive Tissue Atrophy. EMBO Reports (2026)

Source Data for Saravanan and Kane," Early Responses to Hyperosmotic Stress at the Yeast Vacuole". Open MIND (2026)

Abstract 2474 Rogdi is the Homolog of Yeast Rav2 and a Novel Rabconnectin-3 Subunit. Journal of Biological Chemistry (2025)

Abstract 2792 Metabolic Modulation of V-Atpase Proton Pump in the Aging Lysosome. Journal of Biological Chemistry (2025)

Bps2025 - Structure of Yeast Rave Bound to a Partial V1 Complex. Biophysical Journal (2025)

yeastcrystallographyprotein structurephysicsmolecular biologyyeast rave boundpartial v1 complexstructural biology

Early Responses to Hyperosmotic Stress at the Yeast Vacuole. bioRxiv (Cold Spring Harbor Laboratory) (2025)

gene expressionmolecular and cellular biologyhyperosmotic stressyeastmolecular cell biologyfungal physiologyphysiologymolecular biologystress (biology)cellular physiologycellular biochemistry

Mdm38/Letm1 Couples Ion Homeostasis and Proteostatic Mechanisms in the Inner Mitochondrial Membrane. bioRxiv (Cold Spring Harbor Laboratory) (2025)

biophysicsmitochondrial functionproteostatic mechanismsbiochemistrymembrane biologymolecular biologyinner mitochondrial membrane

The Rogdi Protein Mutated in Kohlschutter–Tonz Syndrome is a Novel Subunit of the Rabconnectin-3 Complex Implicated in V-Atpase Assembly. Journal of Biological Chemistry (2025)

V‐Atpase Disassembly at the Yeast Lysosome‐Like Vacuole is a Phenotypic Driver of Lysosome Dysfunction in Replicative Aging. Aging Cell (2025)

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