Faculty

Institution

Unit

Venue

Pankaj Desai

Professor and Chair Division of Pharmaceutical Sciences

University of Cincinnati

Affiliations

College of Pharmacy

Pharmaceutical Sciences

Pankaj Desai is currently serving as a College Of Pharmacy Professor and Chair Division of Pharmaceutical Sciences at University of Cincinnati.

Honors

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Experiences

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Education

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Pankaj Desai

University of Cincinnati

Professor and Chair Division of Pharmaceutical Sciences

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pharmacology oncology medicine cancer treatment cancer research medicinal research pharmacokinetics pharmacotherapy cancer care radiation oncology brain tumor research cancer biology anti-cancer agents drug metabolism tumor targeting tumor biology drug delivery enzyme inhibition drug discovery clinical research clinical pharmacology pharmacological research drug development cellular therapy health sciences hepatology molecular cancer liver physiology laboratory medicine cancer management drug targeting primary human hepatocytes blood purification antiviral therapy vascular access food science antiviral drug development translational pharmacology drug safety advanced solid malignancies respiratory medicine vascular biology pharmaceutical sciences comparative analysis antiviral drugs therapeutic efficacy neonatology melanoma novel therapies fungal sphingolipids targeted delivery brain pharmacokinetics receptor activation clinical nutrition nutritional biochemistry human nutrition medical nutrition nutritional sciences fungal biology redox signaling clinical radiation oncology pharmaceutical research intracerebral microdialysis lipid analysis nutrient bioavailability nutrient physiology dietary health pure isoflavones healthy humans healthy women dose-response effects soy isoflavones typical dietary intakes human hepatocytes clinical drug interactions excellent model hiv system pharmacology future medicinal chemistry applied pharmacology brain tumors

Notable Scholarly Works

Notable Federal Grants

Collaborators

Integrative Multi-Omics Analysis Identifies Nuclear Factor I as a Key Driver of Dysregulated Purine Metabolism in Dipg. bioRxiv (Cold Spring Harbor Laboratory) (2025)

gene expressionomicsproteomicsfunctional genomicsomics integrationsystems biologydysregulated purine metabolismgeneticskey drivermolecular cell biologymolecular metabolismgene functioncell metabolismpathway analysiscellular biochemistrycell biology

Vancomycin Dosing in Neonates: Enhancing Outcomes Using Population Pharmacokinetics and Simulation. Frontiers in Antibiotics (2025)

medicinetherapeutic drug monitoringpediatric anesthesiapharmacokineticspharmacotherapyapplied pharmacologydrug resistanceantibioticsneonatologypediatricsphysiologically-based pharmacokinetic modelingpopulation pharmacokinetics

Abstract 2119: Translational Research to Facilitate Development of Novel Therapeutic Combinations of Letrozole for the Treatment of Glioblastoma. Cancer Research (2024)

Aniruddha Sunil KarveBhavesh Babulal GabaniSidharth Nitin GadgilShravani Parag KulkarniGary A. GudelskyPankaj B. Desai

translational researchtreatment developmentnovel therapiesnovel therapeutic combinationsneuro-oncologydrug developmentneurologymedicinecancer carecancer biologycancer researchcancer treatmentenzyme inhibitionpharmacologybrain tumor researchpharmacotherapyoncologyclinical researchmedicinal research

Abstract 703: Gaba(a) Receptor Activation Drives Gabarap-Nix Mediated Autophagy to Radiosensitize Primary and Metastatic Lung Adenocarcinoma Tumors. Cancer Research (2024)

Debanjan BhattacharyaRiccardo BarrileDonatien Kamdem ToukamVaibhavkumar S. GawaliLaura KallayTaukir AhmedHawley BrownSepideh RezvanianAniruddha KarvePankaj B. DesaiMario MedvedovicKyle WangDan IonascuNusrat HarunChenran WangAndrew M. BaschnagelJoshua A. KritzerJames CookDaniel A. Pomeranz KrummelSoma Sengupta

receptor activationautophagytumor targetingcancer caremolecular canceranti-cancer agentscancer biologyhealth sciencescancer researchcancer growthcancer treatmenttumor biologyreceptorspharmacologythoracic oncologyradiation oncologyclinical researchoncologygabarap-nix mediated autophagymedicinal research

A Multimodal Drug–Diet–Immunotherapy Combination Restrains Melanoma Progression and Metastasis. Cancer Research (2024)

Nicole OatmanMruniya V. GawaliSunny CongroveRomán CáceresAbitha SukumaranNishtha GuptaNarmadha MurugesanPriyanka AroraSrividhya SubramanianKwangmin ChoiZalfa Abdel-MalekJulie A. ReiszDaniel StephensonRavi AmaravadiPankaj DesaiAngelo D’AlessandroKakajan KomurovBiplab Dasgupta

metastasismelanomatherapeutic efficacymedicinecancer carecancer managementvascular biologycancer biologydermatologyleukemiacancer researchcancer immunotherapymultimodal drug-diet-immunotherapy combinationcancer treatmentimmunotherapypharmacologymelanoma progressiononcologymedicinal researchcellular therapy

A Phase 0/I Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination With Standard Therapy in Recurrent High-Grade Gliomas. Clinical Cancer Research (2024)

neurologypharmacologygliomasstandard therapyfuture medicinal chemistryphase 0/ibrain tumor researchradiopharmaceutical therapypharmacotherapymetronomic therapyoncologyneuro-oncologycancer treatmentrecurrent high-grade gliomas

A Review of Approaches to Potentiate the Activity of Temozolomide Against Glioblastoma to Overcome Resistance. International Journal of Molecular Sciences (2024)

Aniruddha S. KarveJanki M. DesaiSidharth N. GadgilNimita DaveTrisha M. Wise-DraperGary A. GudelskyTimothy N. PhoenixBiplab DasGuptaLalanthica YogendranSoma SenguptaDavid R. PlasPankaj B. Desai

tumor targetingmedicinedrug safetypharmacologybrain tumor researchmolecular sciencepharmacotherapyneuropharmacologydrug resistanceanti-cancer agentsoncologyneuro-oncologymedicinal researchdrug targetingcancer treatmenttumor biologyneuroscience

Data From a Phase 0/I Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination With Standard Therapy in Recurrent High-Grade Gliomas. (2024)

Pankaj B. DesaiAniruddha S. KarveMisam ZawitPriyanka AroraNimita DaveJoy AwosikaNingjing LiBethany FuhrmanMario MedvedovicLarry SallansAdy KendlerBiplab DasGuptaDavid PlasRichard CurryMario ZuccarelloRekha ChaudharySoma SenguptaTrisha M. Wise-Draper

drug safetypharmacologygliomastolerability studystandard therapyradiation oncologybrain tumor researchneuropharmacologyoncologyrecurrent high-grade gliomas

Dipg-17. Dysregulated Purine Metabolism in a Lethal Childhood Brainstem Tumor Reveals New Treatment Strategies With Old Drugs. Neuro-Oncology (2024)

Ian MersichSunny CongroveMatthew HorcharRoman CaceresJanki DesaiPankaj DesaiLarry SallansJulie HainesRanjith MenonCharles StevensonPeter de BlankNatasha Pillay-SmileyTrent HummelAli TavassoliAngelo D’AlessandroTimothy PhoenixBiplab Dasgupta

nanomedicineold drugspurine metabolismneuro-oncologyneurologytumor targetingcancer caremolecular cancerneuropharmacologycancer biologymolecular evidencecancer researchurologycancer treatmentpharmacologybrain tumor researchredox biologydrug purityoncologymedicinal research

Exth-64. Mechanisms of Mitochondrial Complex-I Sensitivity in Gbm. Neuro-Oncology (2024)

Biplab DasguptaMatthew HorcharMruniya GawaliPankaj DesaiKwangmin ChoiAngelo D’Alessandro

neurologyneuropsychopharmacologygene expressionmitochondrial dynamicsneuroimagingsystems biologybrain tumor researchmitochondrial functionmolecular regulationmitochondrial complex-i sensitivitymolecular neurodegenerationneuro-oncologymitochondrial biogenesismitophagyoxidative stressneuroscienceneuroanatomy

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Pankaj Desai

Professor and Chair Division of Pharmaceutical Sciences

University of Cincinnati

Affiliations

College of Pharmacy

Pharmaceutical Sciences

Pankaj Desai is currently serving as a College Of Pharmacy Professor and Chair Division of Pharmaceutical Sciences at University of Cincinnati.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Pankaj Desai

University of Cincinnati

Professor and Chair Division of Pharmaceutical Sciences

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Integrative Multi-Omics Analysis Identifies Nuclear Factor I as a Key Driver of Dysregulated Purine Metabolism in Dipg. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Vancomycin Dosing in Neonates: Enhancing Outcomes Using Population Pharmacokinetics and Simulation. Frontiers in Antibiotics (2025)

Abstract 2119: Translational Research to Facilitate Development of Novel Therapeutic Combinations of Letrozole for the Treatment of Glioblastoma. Cancer Research (2024)

Aniruddha Sunil KarveBhavesh Babulal GabaniSidharth Nitin GadgilShravani Parag KulkarniGary A. GudelskyPankaj B. Desai

Abstract 703: Gaba(a) Receptor Activation Drives Gabarap-Nix Mediated Autophagy to Radiosensitize Primary and Metastatic Lung Adenocarcinoma Tumors. Cancer Research (2024)

A Multimodal Drug–Diet–Immunotherapy Combination Restrains Melanoma Progression and Metastasis. Cancer Research (2024)

A Phase 0/I Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination With Standard Therapy in Recurrent High-Grade Gliomas. Clinical Cancer Research (2024)

A Review of Approaches to Potentiate the Activity of Temozolomide Against Glioblastoma to Overcome Resistance. International Journal of Molecular Sciences (2024)

Aniruddha S. KarveJanki M. DesaiSidharth N. GadgilNimita DaveTrisha M. Wise-DraperGary A. GudelskyTimothy N. PhoenixBiplab DasGuptaLalanthica YogendranSoma SenguptaDavid R. PlasPankaj B. Desai

Data From a Phase 0/I Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination With Standard Therapy in Recurrent High-Grade Gliomas. (2024)

drug safetypharmacologygliomastolerability studystandard therapyradiation oncologybrain tumor researchneuropharmacologyoncologyrecurrent high-grade gliomas

Dipg-17. Dysregulated Purine Metabolism in a Lethal Childhood Brainstem Tumor Reveals New Treatment Strategies With Old Drugs. Neuro-Oncology (2024)

Exth-64. Mechanisms of Mitochondrial Complex-I Sensitivity in Gbm. Neuro-Oncology (2024)

Biplab DasguptaMatthew HorcharMruniya GawaliPankaj DesaiKwangmin ChoiAngelo D’Alessandro

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