Faculty

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Unit

Venue

Pamela Kozlowski

Louisiana State University Health Sciences Center, New Orleans

Affiliations

School of Graduate Studies

Pamela Kozlowski is a High Senior Professor at Louisiana State University Health Sciences Center, New Orleans. Her research focuses on HIV-1 vaccine development, mucosal immunology, and adjuvant-mediated immune responses, with particular emphasis on inducing polymeric IgA antibodies and Fc-mediated effector functions in nonhuman primate models. Her recent work demonstrates that intradermal modified vaccinia Ankara immunization protects against intravaginal tier 2 simian-human immunodeficiency virus challenges in female macaques, and that dmLT and alum adjuvants enhance HIV-1 vaccine immunogenicity. She also investigates SARS-CoV-2 booster vaccine efficacy against emerging variants, including mRNA-1273 and Novavax formulations, and has published extensively on vaccine-induced antibody persistence and Tfh profiles in rhesus macaques. Her contributions span public health and mammalian biology, advancing next-generation vaccine strategies against HIV and COVID-19.

Honors

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Education

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Pamela Kozlowski

Louisiana State University Health Sciences Center, New Orleans

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immunology vaccination vaccines hiv virology infectious diseases vaccine development immune responses vaccine research public health virus research general virology medical virology mammalian biology infection control microbiology immunity (medicine) clinical microbiology antiviral research virus-host interactions rhesus macaques sars-cov-2 adaptive immune system veterinary medicine virus eradication viral genetics mucosal immunology clinical immunology vaccine design viral pathogenesis vaccine efficacy mucosal vaccination innate immune system vaccine safety cellular immune responses infant macaques infant rhesus macaques communicable diseases viral persistence virus transmission antiviral responses human retrovirus viral evolution disease transmission medicinal research respiratory medicine avian biology venereology immunopathology antibody screening host response transplant infectious diseases antibody engineering t-regulatory cell viral replication diagnostic microbiology virus epidemiology oral cavity nonhuman primates non-human primates mucosal immune responses chlamydia trachomatis infection antibody responses humoral immunity gut microbes women's studies therapeutic vaccines menstrual cycle molecular microbiology mucosal vaccines genital tract secretions vaginal immunization differential induction systemic antibody responses wick method human rectal secretions

Notable Scholarly Works

Notable Federal Grants

Collaborators

Immunogenicity and Protection Mediated by Dmlt and Alum Adjuvants for an Hiv-1 Vaccine. Frontiers in Immunology (2026)

allergyvaccinesimmunity (medicine)virus eradicationinfectious diseasesmedical virologyvirologyreproductive immunologyvirus researchexperimental medicineimmunologyantiviral researchimmunotherapyimmune responsesvaccinationgeneral virologyhiv

A Modified Vaccinia Ankara Vaccine Expressing Spike and Nucleocapsid Protects Rhesus Macaques Against Sars-Cov-2 Delta Infection. UNC Libraries (2024)

vaccinesimmunity (medicine)virus eradicationsars-cov-2neurovirologymedical virologyvirologyinfectious diseasesinfectious diseases (medical specialty)avian medicinevirus researchcommunicable diseasesimmunologyantiviral researchvaccinationgeneral virology

Author Response: Tailoring Tfh Profiles Enhances Antibody Persistence to a Clade C Hiv-1 Vaccine in Rhesus Macaques. (2024)

Anil VermaChase E HawesSonny R ElizaldiJustin C SmithDhivyaa RajasundaramGabriel Kristian PedersenXiaoying ShenLaTonya D WilliamsGeorgia D TomarasPamela A KozlowskiRama Rao AmaraSmita S Iyer

vaccine developmentvaccinestailoring tfh profileshealth sciencesvirologymammalian biologyrhesus macaquesauthor responseimmunologypublic healthimmune responsesantibody persistencevaccinationhiv

Induction of Tier 2 Hiv-Neutralizing Iga Antibodies in Rhesus Macaques Vaccinated With Bg505.664 Sosip. Vaccines (2024)

Justin C. SmithPrabhu S. ArunachalamTraci H. LegereLisa A. CavaciniEric HunterBali PulendranRama R. AmaraPamela A. Kozlowski

vaccinesrhesus macaquesimmunologyvaccine researchvaccinationhiv-neutralizing iga antibodieshiv

Vaccine-Induced, High-Magnitude Hiv Env-Specific Antibodies With Fc-Mediated Effector Functions Are Insufficient to Protect Infant Rhesus Macaques Against Oral Shiv Infection. UNC Libraries (2024)

vaccinesimmunity (medicine)virus eradicationtransplant infectious diseasesneurovirologymedical virologyvirologyinfectious diseasesreproductive immunologyinfectious diseases (medical specialty)virus researchimmunologyantiviral researchvaccinationgeneral virologyhivepidemiology

Efficacy of Mrna-1273 and Novavax Ancestral or Ba.1 Spike Booster Vaccines Against Sars-Cov-2 Ba.5 Infection in Nonhuman Primates. Science Immunology (2023)

Nanda Kishore RouthuSamuel David StampferLilin LaiAkil AkhtarXin TongDansu YuanTaras M. ChiczRyan P. McNamaraKishor JakkalaMeredith E. Davis-GardnerE. Lovisa St PierreBrandon SmithKristyn Moore GreenNadia GoldenBreanna PicouSherrie M. JeanJennifer WoodJoyce CohenIan N. MooreNita PatelMimi Guebre-XabierGale SmithGreg GlennPamela A. KozlowskiGalit AlterRafi AhmedMehul S. SutharRama Rao Amara

vaccine developmentvaccinesnonhuman primatesinfection controlavian biologysars-cov-2infectious diseasescovid-19avian medicinearbovirusvaccine efficacyimmunologyvaccine researchimmune responsesvaccinationvaccine designepidemiology

Infant Rhesus Macaques Immunized Against Sars-Cov-2 Are Protected Against Heterologous Virus Challenge One Year Later. eScholarship (California Digital Library) (2023)

Intradermal but Not Intramuscular Modified Vaccinia Ankara Immunizations Protect Against Intravaginal Tier2 Simian-Human Immunodeficiency Virus Challenges in Female Macaques. Nature Communications (2023)

Venkata S. BollimpelliPradeep B. J ReddySailaja GangadharaTysheena P. CharlesSamantha L. BurtonGregory K. TharpTiffany M. StylesCelia C. LabrancheJustin C. SmithAmit A. UpadhyayAnusmita SahooTraci LegereAyalnesh ShiferawVijayakumar VeluTianwei YuMark TomaiJohn VasilakosSudhir P. KasturiGeorge M. ShawDavid MontefioriSteven E. BosingerPamela A. KozlowskiBali PulendranCynthia A. DerdeynEric HunterRama R. Amara

vaccinesviral evolutionfemale macaquesdiagnostic virologyimmune responsesvaccinia ankara immunizationsviral persistencegeneticsavian biologydermatologyvaccinationvaccine developmentvirologymedical virologyvirus researchimmunologyimmunopathologymammalian biologyhivgeneral virology

In Vivo Treatment With Insulin-Like Growth Factor 1 Reduces Ccr5 Expression on Vaccine-Induced Activated Cd4+ T-Cells. Vaccines (2023)

Massimiliano BissaVeronica GalliLuca SchifanellaMonica VaccariMohammad Arif RahmanGiacomo GoriniNicolò BinelloSarkis SarkisAnna GutowskaIsabela Silva de CastroMelvin N. DosterRamona MolesGuido FerrariXiaoying ShenGeorgia D. TomarasDavid C. MontefioriKombo F. N’guessanDominic Paquin-ProulxPamela A. KozlowskiDavid J. VenzonHyoyoung Choo-WosobaMatthew W. BreedJoshua KramerGenoveffa Franchini

vaccine developmentvaccinesadaptive immune systemmedicinegene expressioncellular immune responsesvaccine efficacycell signalingimmunologyvaccine researchimmune responsesvaccination

Reviewer #1 (Public Review): Tailoring Tfh Profiles Enhances Antibody Persistence to a Clade C Hiv-1 Vaccine in Rhesus Macaques. (2023)

Anil VermaChase E HawesSonny R ElizaldiJustin C. SmithDhivyaa RajasundaramGabriel Kristian PedersenXiaoying ShenLaTonya D WilliamsGeorgia D. TomarasPamela A. KozlowskiRama R. AmaraSmita S. Iyer

vaccine developmentvaccinesinfectious diseasestfh profilesrhesus macaquesvirus researchimmunologyantibody persistencevaccinationhiv

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Pamela Kozlowski

Louisiana State University Health Sciences Center, New Orleans

Affiliations

School of Graduate Studies

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Pamela Kozlowski

Louisiana State University Health Sciences Center, New Orleans

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Immunogenicity and Protection Mediated by Dmlt and Alum Adjuvants for an Hiv-1 Vaccine. Frontiers in Immunology (2026)

A Modified Vaccinia Ankara Vaccine Expressing Spike and Nucleocapsid Protects Rhesus Macaques Against Sars-Cov-2 Delta Infection. UNC Libraries (2024)

Author Response: Tailoring Tfh Profiles Enhances Antibody Persistence to a Clade C Hiv-1 Vaccine in Rhesus Macaques. (2024)

Anil VermaChase E HawesSonny R ElizaldiJustin C SmithDhivyaa RajasundaramGabriel Kristian PedersenXiaoying ShenLaTonya D WilliamsGeorgia D TomarasPamela A KozlowskiRama Rao AmaraSmita S Iyer

vaccine developmentvaccinestailoring tfh profileshealth sciencesvirologymammalian biologyrhesus macaquesauthor responseimmunologypublic healthimmune responsesantibody persistencevaccinationhiv

Induction of Tier 2 Hiv-Neutralizing Iga Antibodies in Rhesus Macaques Vaccinated With Bg505.664 Sosip. Vaccines (2024)

Justin C. SmithPrabhu S. ArunachalamTraci H. LegereLisa A. CavaciniEric HunterBali PulendranRama R. AmaraPamela A. Kozlowski

vaccinesrhesus macaquesimmunologyvaccine researchvaccinationhiv-neutralizing iga antibodieshiv

Vaccine-Induced, High-Magnitude Hiv Env-Specific Antibodies With Fc-Mediated Effector Functions Are Insufficient to Protect Infant Rhesus Macaques Against Oral Shiv Infection. UNC Libraries (2024)

Efficacy of Mrna-1273 and Novavax Ancestral or Ba.1 Spike Booster Vaccines Against Sars-Cov-2 Ba.5 Infection in Nonhuman Primates. Science Immunology (2023)

Infant Rhesus Macaques Immunized Against Sars-Cov-2 Are Protected Against Heterologous Virus Challenge One Year Later. eScholarship (California Digital Library) (2023)

In Vivo Treatment With Insulin-Like Growth Factor 1 Reduces Ccr5 Expression on Vaccine-Induced Activated Cd4+ T-Cells. Vaccines (2023)

vaccine developmentvaccinesadaptive immune systemmedicinegene expressioncellular immune responsesvaccine efficacycell signalingimmunologyvaccine researchimmune responsesvaccination

Reviewer #1 (Public Review): Tailoring Tfh Profiles Enhances Antibody Persistence to a Clade C Hiv-1 Vaccine in Rhesus Macaques. (2023)

Anil VermaChase E HawesSonny R ElizaldiJustin C. SmithDhivyaa RajasundaramGabriel Kristian PedersenXiaoying ShenLaTonya D WilliamsGeorgia D. TomarasPamela A. KozlowskiRama R. AmaraSmita S. Iyer

vaccine developmentvaccinesinfectious diseasestfh profilesrhesus macaquesvirus researchimmunologyantibody persistencevaccinationhiv

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