Faculty

Institution

Unit

Venue

Nour-Eddine Rhaleb

Professor

Wayne State University

Affiliations

Graduate School

School of Medicine

Physiology

Nour-eddine Rhaleb is currently serving as a Graduate School Professor at Wayne State University.

Honors

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Experiences

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Education

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Nour-Eddine Rhaleb

Wayne State University

Professor

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pharmacology physiology cardiology hypertension cardiovascular research medicine receptors neuroscience vascular biology cardiovascular physiology nephrology circulatory physiology neuropharmacology medicinal research mammalian biology respiratory medicine inflammation liver physiology blood pressure electrophysiology animal physiology cardiovascular function endocrinology myocardial infarction cytokines cellular physiology human physiology molecular physiology cardiovascular pharmacology renal function pharmacological research thrombosis enzyme inhibition applied physiology receptor (biochemistry) anti-inflammatory angiology pharmacotherapy mammalian physiology clinical physiology antihypertensive therapy functional modification cardiac function cardiac fibroblasts clinical lipidology inhibitory activity angiogenesis experimental biology cardiac remodeling in vivo systems clinical medicine renal care renal pathophysiology selective agonists biological activities prolyl oligopeptidase guinea pig ileum heme homeostasis fibrosis kin recognition physiological regulation fibroblast growth factors treatment and prevention cohort studies neuroprotection veterinary physiology clinical pharmacology neurokinin receptors kallikrein-kinin system structure-activity studies renovascular hypertension isolated vessels nitric oxide hypertensive rats structure-activity study vasoactive peptides

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract Tac275: Combined High-Fat and High-Salt Diet Induces Salt-Sensitive Hypertension, Upregulates Nkcc2 Expression and Decreases Renal Function in C57Bl/6J Mice. Hypertension (2025)

hypertensioninflammationrenal pathophysiologymetabolic syndromerenal functioncell signalingimmunologynephrologyphysiology

Ac-Sdkp and Eplerenone Confer Additive Cardioprotection Against Angiotensin II-Induced Cardiac Injury in C57Bl/6J Mice. Journal of Molecular and Cellular Cardiology Plus (2025)

pharmacologycardiovascular researchcardiologycardiovascular pharmacologycirculatory physiologycell biologyphysiology

Deletion of Chop in Beta Cell Protects Mice From Cardiovascular Complications in Type 2 Diabetes: Evidence From a Pre-Clinical Mouse Model. Journal of Molecular and Cellular Cardiology Plus (2025)

Endothelial Chop as a Central Mechanism in Renovascular Hypertension-Induced Vascular Endothelial Dysfunction and Cardiac Fibrosis. Cellular and Molecular Life Sciences (2025)

Novel Insights Into Beta Cell Er Stress Chop and Its Role in Hfpef Development. Cardiovascular Diabetology (2025)

Sex Differences in a Preclinical Model of Type II Cardiorenal Syndrome With Loop Diuretic Resistance. Physiology (2025)

cardiovascular researchcirculatory physiologycardiovascular diseasecardiovascular functionphysiology

Abstract 38: Loop Diuretic Resistance in a Preclinical Model of Cardiorenal Syndrome 2: Role of Enhanced Distal Convoluted Tubule Sodium Transport. Hypertension (2024)

Isaac BaidenMariela MendezPablo OrtizNourEddine RhalebTang-Dong LiaoJiang Xu

hypertensiontubule sodium transporthealth sciencespreclinical modelloop diuretic resistance

Ac-Sdkp Attenuates Er Stress-Stimulated Collagen Production in Cardiac Fibroblasts by Inhibiting Chop-Mediated Nf-κB Expression. Frontiers in Pharmacology (2024)

Hamid SuhailHongmei PengKhalid MatrouguiNour-Eddine Rhaleb

medicineliver physiologyhost specificitymolecular evidencestress-stimulated collagen productionregenerative medicinechop-mediated nf-kb expressioninhibitory activitymembrane biologyfunctional modificationdermatologypharmacological researchpharmacologyreceptorscardiologyconformational studiesmammalian biologyenzyme inhibitioncardiac fibroblastspersonalized medicinemedicinal research

Disruption of Er Stress Chop in Beta Cells Protects From Hfpef Pathogenesis. Physiology (2024)

Balaji SrinivasPaula FortunoSouad BelmadaniNour-Eddine RhalebKhalid Matrougui

geneticsbeta cellsmembrane biologyhfpef pathogenesispathogenesiser stress chopcellular physiologycell biologyphysiology

Alms1 Ko Rat: A New Model of Metabolic Syndrome With Spontaneous Hypertension. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Ankita B. JaykumarSumit R. MonuMariela MendezNour-Eddine RhalebPablo A. Ortiz

geneticsanimal physiologyspontaneous hypertensionhealth sciencesendocrinologymetabolic syndromephysiology

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Nour-Eddine Rhaleb

Professor

Wayne State University

Affiliations

Graduate School

School of Medicine

Physiology

Nour-eddine Rhaleb is currently serving as a Graduate School Professor at Wayne State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Nour-Eddine Rhaleb

Wayne State University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract Tac275: Combined High-Fat and High-Salt Diet Induces Salt-Sensitive Hypertension, Upregulates Nkcc2 Expression and Decreases Renal Function in C57Bl/6J Mice. Hypertension (2025)

hypertensioninflammationrenal pathophysiologymetabolic syndromerenal functioncell signalingimmunologynephrologyphysiology

Ac-Sdkp and Eplerenone Confer Additive Cardioprotection Against Angiotensin II-Induced Cardiac Injury in C57Bl/6J Mice. Journal of Molecular and Cellular Cardiology Plus (2025)

pharmacologycardiovascular researchcardiologycardiovascular pharmacologycirculatory physiologycell biologyphysiology

Deletion of Chop in Beta Cell Protects Mice From Cardiovascular Complications in Type 2 Diabetes: Evidence From a Pre-Clinical Mouse Model. Journal of Molecular and Cellular Cardiology Plus (2025)

Endothelial Chop as a Central Mechanism in Renovascular Hypertension-Induced Vascular Endothelial Dysfunction and Cardiac Fibrosis. Cellular and Molecular Life Sciences (2025)

Novel Insights Into Beta Cell Er Stress Chop and Its Role in Hfpef Development. Cardiovascular Diabetology (2025)

Sex Differences in a Preclinical Model of Type II Cardiorenal Syndrome With Loop Diuretic Resistance. Physiology (2025)

cardiovascular researchcirculatory physiologycardiovascular diseasecardiovascular functionphysiology

Abstract 38: Loop Diuretic Resistance in a Preclinical Model of Cardiorenal Syndrome 2: Role of Enhanced Distal Convoluted Tubule Sodium Transport. Hypertension (2024)

Isaac BaidenMariela MendezPablo OrtizNourEddine RhalebTang-Dong LiaoJiang Xu

hypertensiontubule sodium transporthealth sciencespreclinical modelloop diuretic resistance

Ac-Sdkp Attenuates Er Stress-Stimulated Collagen Production in Cardiac Fibroblasts by Inhibiting Chop-Mediated Nf-κB Expression. Frontiers in Pharmacology (2024)

Hamid SuhailHongmei PengKhalid MatrouguiNour-Eddine Rhaleb

Disruption of Er Stress Chop in Beta Cells Protects From Hfpef Pathogenesis. Physiology (2024)

Balaji SrinivasPaula FortunoSouad BelmadaniNour-Eddine RhalebKhalid Matrougui

geneticsbeta cellsmembrane biologyhfpef pathogenesispathogenesiser stress chopcellular physiologycell biologyphysiology

Alms1 Ko Rat: A New Model of Metabolic Syndrome With Spontaneous Hypertension. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Ankita B. JaykumarSumit R. MonuMariela MendezNour-Eddine RhalebPablo A. Ortiz

geneticsanimal physiologyspontaneous hypertensionhealth sciencesendocrinologymetabolic syndromephysiology

1
2
3
4
5
15
10 / page

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