Faculty

Institution

Unit

Venue

Ninian Blackburn

Oregon Health & Science University

Affiliations

OGI School of Science and Engineering

Department Of Chemistry, Biochemistry And Molecular Biology

NoneNinian Blackburn is currently serving as a Chemistry, Biochemistry And Molecular Biology faculty at Oregon Health & Science University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Ninian Blackburn

Oregon Health & Science University

You can click a keyword to filter the displayed items

biochemistry enzymes transition metal chemistry inorganic chemistry coordination chemistry chemistry biological inorganic chemistry molecular biology redox biology protein science structural biology chemical biology protein structure biophysical chemistry biological chemistry biophysics protein chemistry enzyme catalysis redox chemistry metalloproteins structural molecular biology catalysis chemical sciences biochemical sciences biomolecular structure enzyme inhibition structural chemistry bioactive metal structure-function enzyme kinetics peptidylglycine monooxygenase membrane biology biocatalysis free radical biology coordination complex molecular structure bioenergetics bioorganometallic chemistry x-ray absorption studies metals protein transport catalyst activation inorganic compounds exafs studies applied microbiology bacteriology bioelectrochemistry trace metals inorganic synthesis copper centers peptidylglycine a-hydroxylating monooxygenase human copper chaperone superoxide dismutase conformational studies carbonyl metabolism molecular catalysis surface reactivity spectroelectrochemistry protein function molecular complexes x-ray absorption spectroscopy type 1 dioxygen-copper reactivity peptide engineering peptide synthesis redox signaling dopamine heme transport heme trafficking structural studies periplasmic proteins catalytic core electron transfer active site protein scaffold key site lignin

Notable Scholarly Works

Notable Federal Grants

Collaborators

Metal-Mediated Peptide Processing. How Copper and Iron Catalyze Diverse Peptide Modifications Such as Amidation and Crosslinking. RSC Chemical Biology (2025)

peptidespeptide engineeringpeptide synthesiscatalysispeptide sciencemetal-mediated peptide processingchemical biologybiomolecular engineeringchemical scienceschemistrybiomoleculespeptide therapeuticstransition metal chemistryprotein engineeringchemical synthesisbiochemistry

The Binuclear Copper State of Peptidylglycine Monooxygenase Visualized Through a Selenium-Substituted Peptidyl-Homocysteine Complex. Dalton Transactions (2025)

binuclear copper stateenzyme inhibitionselenium-substituted peptidyl-homocysteine complexpeptidylglycine monooxygenasechemical biologyenzymesbiological inorganic chemistrymolecular biologybiological chemistrybioorganometallic chemistryenzyme catalysisbiochemical sciencesoxidative stressbiochemistry

Beyond the Coupled Distortion Model: Structural Analysis of the Single Domain Cupredoxin Acop, a Green Mononuclear Copper Centre With Original Features. Dalton Transactions (2024)

biophysicsstructural analysisprotein structurecoupled distortion modeloriginal featureschemistryinorganic chemistrycrystal engineeringstructural biologycrystallographychemical structure

Capturing the Binuclear Copper State of Peptidylglycine Monooxygenase Using a Peptidyl-Homocysteine Lure. Journal of the American Chemical Society (2024)

Katherine W. RushKarsten A. S. EastmanEvan F. WelchVahe BandarianNinian J. Blackburn

medicinal chemistrybiological chemistryenzyme catalysisbiochemistrybinuclear copper statepeptidylglycine monooxygenasecoordination chemistrychemical biologyenzymesprotein scienceprotein chemistrycatalysisbiocatalysisprotein engineeringbiological engineeringtransition metal chemistryenzyme inhibitionbiomolecular engineeringbiological inorganic chemistrypeptidyl-homocysteine lure

Mechanisms of Copper Selectivity and Release by the Metallochaperone Cusf: Insights From Co-Binding, Rapid-Freeze-Quench Exafs, and Unnatural Amino Acid Substitution. Inorganic Chemistry (2024)

Katherine W. RushKatherine B. AlwanA. Tamar ConnerEvan F. WelchNinian J. Blackburn

inorganic compoundscopper selectivitydrug metabolismmetal chain compoundmetalsbiochemistrychemical engineeringcoordination chemistrymetallochaperone cusfinorganic synthesischemical synthesistransition metal chemistrymolecular structurebiological inorganic chemistrymolecular biologystructural molecular biologyinorganic chemistrytrace metalsrapid-freeze-quench exafs

Pathogenic R 163 W Variant of the Copper Chaperone for Sod1 (Ccs) Functions as an Anti-Chaperone. Biochemistry (2024)

Bei ZhangStefanie D. BoydDannie ZhabilovMorgan UllrichNinian J. BlackburnDuane D. Winkler

pathogenesisresidual stressbiochemistrychemical biologyenzymesantiviral responsesbiomoleculesbioelectrochemistryprotein sciencemembrane biologymetalloproteinschemical pathologytransition metal chemistrypathogensenzyme inhibitionbiomolecular engineeringmolecular biologystructural molecular biologycopper chaperone

Ripping and Stitching With Copper. Nature Chemical Biology (2024)

industrial textilecomposite constructionmetal formingmechanical engineering

New Structures Reveal Flexible Dynamics Between the Subdomains of Peptidylglycine Monooxygenase. Implications for an Open to Closed Mechanism. Protein Science (2023)

Renee J. AriasEvan F. WelchNinian J. Blackburn

biological macromoleculesbiophysicspeptidespeptidylglycine monooxygenaseflexible dynamicsstructure-function enzyme kineticsprotein structurebiomolecular structurerelease mechanismenzymesmolecular biologystructural molecular biologyenzyme catalysisstructural biologyprotein scienceprotein foldingbiochemistry

Peptide Selenocysteine Substitutions Reveal Direct Substrate–Enzyme Interactions at Auxiliary Clusters in Radical S -Adenosyl- L -Methionine Maturases. Journal of the American Chemical Society (2023)

Katherine W. RushKarsten A. S. EastmanWilliam M. KincannonNinian J. BlackburnVahe Bandarian

peptidesprotein structureradical (chemistry)enzyme catalysisbiochemistryselenocysteine substitutionsenzymesstructural biologyprotein sciencemembrane biologyprotein chemistrymolecular substratesbiocatalysisauxiliary clustersbiophysicsfree radical biologyredox biologydirect substrate-enzyme interactionsmolecular biologystructural molecular biologyoxidative stress

Copper Monooxygenase Reactivity: Do Consensus Mechanisms Accurately Reflect Experimental Observations?. Journal of Inorganic Biochemistry (2022)

Evan F. WelchKatherine W. RushRenee J. AriasNinian J. Blackburn

copper monooxygenase reactivityenzymesbiological inorganic chemistrybiochemistrytransition metal chemistry

1
2
3
4
5
15
10 / page

Ninian Blackburn

Oregon Health & Science University

Affiliations

OGI School of Science and Engineering

Department Of Chemistry, Biochemistry And Molecular Biology

NoneNinian Blackburn is currently serving as a Chemistry, Biochemistry And Molecular Biology faculty at Oregon Health & Science University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Ninian Blackburn

Oregon Health & Science University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Metal-Mediated Peptide Processing. How Copper and Iron Catalyze Diverse Peptide Modifications Such as Amidation and Crosslinking. RSC Chemical Biology (2025)

The Binuclear Copper State of Peptidylglycine Monooxygenase Visualized Through a Selenium-Substituted Peptidyl-Homocysteine Complex. Dalton Transactions (2025)

Beyond the Coupled Distortion Model: Structural Analysis of the Single Domain Cupredoxin Acop, a Green Mononuclear Copper Centre With Original Features. Dalton Transactions (2024)

biophysicsstructural analysisprotein structurecoupled distortion modeloriginal featureschemistryinorganic chemistrycrystal engineeringstructural biologycrystallographychemical structure

Capturing the Binuclear Copper State of Peptidylglycine Monooxygenase Using a Peptidyl-Homocysteine Lure. Journal of the American Chemical Society (2024)

Katherine W. RushKarsten A. S. EastmanEvan F. WelchVahe BandarianNinian J. Blackburn

Mechanisms of Copper Selectivity and Release by the Metallochaperone Cusf: Insights From Co-Binding, Rapid-Freeze-Quench Exafs, and Unnatural Amino Acid Substitution. Inorganic Chemistry (2024)

Katherine W. RushKatherine B. AlwanA. Tamar ConnerEvan F. WelchNinian J. Blackburn

Pathogenic R 163 W Variant of the Copper Chaperone for Sod1 (Ccs) Functions as an Anti-Chaperone. Biochemistry (2024)

Bei ZhangStefanie D. BoydDannie ZhabilovMorgan UllrichNinian J. BlackburnDuane D. Winkler

Ripping and Stitching With Copper. Nature Chemical Biology (2024)

industrial textilecomposite constructionmetal formingmechanical engineering

New Structures Reveal Flexible Dynamics Between the Subdomains of Peptidylglycine Monooxygenase. Implications for an Open to Closed Mechanism. Protein Science (2023)

Renee J. AriasEvan F. WelchNinian J. Blackburn

Katherine W. RushKarsten A. S. EastmanWilliam M. KincannonNinian J. BlackburnVahe Bandarian

Copper Monooxygenase Reactivity: Do Consensus Mechanisms Accurately Reflect Experimental Observations?. Journal of Inorganic Biochemistry (2022)

Evan F. WelchKatherine W. RushRenee J. AriasNinian J. Blackburn

copper monooxygenase reactivityenzymesbiological inorganic chemistrybiochemistrytransition metal chemistry

1
2
3
4
5
15
10 / page