Faculty

Institution

Unit

Venue

Nancy Carrasco

Professor Adjunct

Yale University

Affiliations

Cellular & Molecular Physiology

Nancy Carrasco is currently serving as a Cellular & Molecular Physiology Professor Adjunct at Yale University.

Honors

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Experiences

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Education

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Nancy Carrasco

Yale University

Professor Adjunct

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endocrinology molecular biology pharmacology physiology thyroid membrane biology genetics endocrine research protein science oncology mammalian biology protein transport molecular physiology tumor biology gene expression metabolism breast cancer medicinal research redox biology membrane transport cancer research biological chemistry thyroid disease cancer biology molecular cancer comparative endocrinology cellular physiology cancer treatment oncogenes animal physiology vascular biology endocrine oncology cancer genomics nutrient physiology endocrine mechanisms molecular regulation transcription regulation intracellular trafficking iodide transport cancer care molecular metabolism geriatric endocrinology clinical medicine tumor targeting breast oncology thyroid gland cellular biochemistry nucleic acids mammary gland thyroid hormone physiological research immunochemistry cancer genetics cellular biology developmental endocrinology endocrine disruptors key site genetic disorders gene function cell trafficking human physiology science studies thyroid iodide transporter molecular analysis post-transcriptional regulation thyroid cancer lactose permease medical significance acute wolff-chaikoff effect extrathyroid pathophysiology medical impact conventional sections clinical applications iodide symporter repression increased malignancy upstream enhancer

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 5814: Towards Treating Prostate Cancer With188Reo4-Using an Engineered Human Sodium/Iodide Symporter (Nis) Protein. Cancer Research (2026)

future medicinal chemistrymolecular medicinemedicinal researchprotein designmolecular cancerprostate cancerbiochemistrychemical biologycancer discoveryprotein engineeringbiochemical sciencestherapeutic targetsbiological chemistrydrug discoveryurologycancer letterbiomolecular engineering

Bps2026 – Engineering Novel Mutant Proteins of the Na+/I− Symporter (Nis) to Broaden Radioiodide Therapy Beyond Thyroid Cancer. Biophysical Journal (2026)

future medicinal chemistryoncogenestumor biologymolecular medicinemedicinal researchcell biologymolecular cancerbiochemistrymedicinal chemistrychemical biologybiochemical sciencesmolecular biologybiological chemistrytherapeutic targetsdrug discoverysignal transductionenzyme inhibition

Overnutrition in Mice Impairs Thyroid Hormone Biosynthesis and Utilization, Causing Hypothyroidism, Despite Remarkable Thyroidal Adaptations. Journal of Clinical Investigation (2026)

reproductive endocrinologymetabolic syndromemetabolismphysiologynutritional biochemistryclinical nutritionnutritionpsychoneuroendocrinologycell metabolismmetabolic pathwaysendocrinologymammalian biologythyroid

Abstract 4698: Towards Treating Prostate Cancer Using an Engineered Sodium/Iodide Symporter (Nis) Protein. Cancer Research (2025)

Haswitha SabbineniAlejandro LlorenteTodd D GiorgioNancy Carrasco

protein scienceprostate cancercancer researchprotein engineeringcancer treatmentbiomolecular engineering

Deep Learning Insights on Na+/I− Symporter (Nis) Transport Cycle. Structural Dynamics (2025)

transport phenomenachemical physicsphysicscomputational physicsdiffusionneural network (machine learning)applied physics

Engineering Substrate Selectivity in the Human Sodium/Iodide Symporter (Nis). bioRxiv (Cold Spring Harbor Laboratory) (2025)

chemical sciencesanalytical chemistrybiochemistrychemical biologybiochemical scienceschemistrybiophysical chemistry

12611 the Thyroid Adapts Remarkably to Overnutrition to Mitigate Hypothyroidism. Journal of the Endocrine Society (2024)

Jessica RampyAlejandra Paola Torres ManzoKendra HoffsmithMatthew Aaron LobergHuiying WangVivian L WeissNancy Carrasco

public healthnutritionthyroid diseaseendocrinologythyroid

Systemic Inhibition of De Novo Purine Biosynthesis Prevents Weight Gain and Improves Metabolic Health by Increasing Thermogenesis and Decreasing Food Intake. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Jacob W. MyersWoo Yong ParkAlexander M. EddieAbhijit B. ShindePraveena PrasadAlexandria C. MurphyMichael Z. LeonardJulia A. PinetteJessica J. RampyClaudia MontufarZayedali ShaikhTara T. HickmanGarrett N. ReynoldsNathan C. WinnLouise LantierSun H. PeckKatie C. CoateRoland W. SteinNancy CarrascoErin S. CalipariMelanie R. McReynoldsElma Zaganjor

metabolic syndromemetabolismenergy metabolismmolecular metabolismsystemic inhibitionmetabolic regulationpurine biosynthesis preventsmetabolic pathwaysbiochemistryfood intakemolecular biologysystems biologyobesitybiosynthesisweight disorders

Data From Iodide Transporter Nis Regulates Cancer Cell Motility and Invasiveness by Interacting With the Rho Guanine Nucleotide Exchange Factor Larg. (2023)

Claire LacosteJulie HervéMyriam Bou NaderAlexandre Dos SantosNicolas MoniauxYannick ValogneRodrick MontjeanOlivier DorseuilDidier SamuelDoris CassioCarla PortulanoNancy CarrascoChristian BréchotJamila Faivre

transport phenomenacharge carrier transportneuroscienceprotein transportpharmacologydata sciencetumor biologyiodide transporter niscell motilitycancer cellscancer cell motilitymembrane transportmolecular cancercancer biologymolecular physiologymembrane biologyredox biologyoncologyneuro-oncology

Structural Insights Into the Mechanism of the Sodium/Iodide Symporter. Nature (2022)

Silvia RaveraJuan Pablo NicolaGlicella Salazar-De SimoneFred J. SigworthErkan KarakasL. Mario AmzelMario A. BianchetNancy Carrasco

biophysicsphysiologystructural biologyneuroscience

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Nancy Carrasco

Professor Adjunct

Yale University

Affiliations

Cellular & Molecular Physiology

Nancy Carrasco is currently serving as a Cellular & Molecular Physiology Professor Adjunct at Yale University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Nancy Carrasco

Yale University

Professor Adjunct

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 5814: Towards Treating Prostate Cancer With188Reo4-Using an Engineered Human Sodium/Iodide Symporter (Nis) Protein. Cancer Research (2026)

Bps2026 – Engineering Novel Mutant Proteins of the Na+/I− Symporter (Nis) to Broaden Radioiodide Therapy Beyond Thyroid Cancer. Biophysical Journal (2026)

Overnutrition in Mice Impairs Thyroid Hormone Biosynthesis and Utilization, Causing Hypothyroidism, Despite Remarkable Thyroidal Adaptations. Journal of Clinical Investigation (2026)

Abstract 4698: Towards Treating Prostate Cancer Using an Engineered Sodium/Iodide Symporter (Nis) Protein. Cancer Research (2025)

Haswitha SabbineniAlejandro LlorenteTodd D GiorgioNancy Carrasco

protein scienceprostate cancercancer researchprotein engineeringcancer treatmentbiomolecular engineering

Deep Learning Insights on Na+/I− Symporter (Nis) Transport Cycle. Structural Dynamics (2025)

transport phenomenachemical physicsphysicscomputational physicsdiffusionneural network (machine learning)applied physics

Engineering Substrate Selectivity in the Human Sodium/Iodide Symporter (Nis). bioRxiv (Cold Spring Harbor Laboratory) (2025)

chemical sciencesanalytical chemistrybiochemistrychemical biologybiochemical scienceschemistrybiophysical chemistry

12611 the Thyroid Adapts Remarkably to Overnutrition to Mitigate Hypothyroidism. Journal of the Endocrine Society (2024)

Jessica RampyAlejandra Paola Torres ManzoKendra HoffsmithMatthew Aaron LobergHuiying WangVivian L WeissNancy Carrasco

public healthnutritionthyroid diseaseendocrinologythyroid

Data From Iodide Transporter Nis Regulates Cancer Cell Motility and Invasiveness by Interacting With the Rho Guanine Nucleotide Exchange Factor Larg. (2023)

Structural Insights Into the Mechanism of the Sodium/Iodide Symporter. Nature (2022)

Silvia RaveraJuan Pablo NicolaGlicella Salazar-De SimoneFred J. SigworthErkan KarakasL. Mario AmzelMario A. BianchetNancy Carrasco

biophysicsphysiologystructural biologyneuroscience

1
2
3
4
5
12
10 / page

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