Faculty

Institution

Unit

Venue

J. Najjar

Professor

Ohio University

Affiliations

Heritage College of Osteopathic Medicine

Biomedical Sciences

J. Najjar is currently serving as a Biomedical Sciences Professor at Ohio University.

Honors

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Experiences

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Education

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J. Najjar

Ohio University

Professor

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endocrinology physiology pharmacology liver physiology hepatology biochemistry health sciences membrane biology gene expression molecular physiology mammalian biology endocrine research metabolism liver disease hematology cell signaling vascular biology insulin signaling cell adhesion obesity cellular physiology medicinal research biological chemistry protein science metabolic syndrome metabolic regulation cell regulation animal physiology experimental medicine respiratory medicine cardiovascular research cell metabolism comparative endocrinology renal function clinical biochemistry enzyme inhibition molecular regulation cancer biology receptor tyrosine kinases endocrine mechanisms insulin clearance male mice in vivo systems knockout mice gene function hepatic steatosis clinical medicine receptor (biochemistry) transcription regulation protein expression gene regulation functional regulation cellular biology host factors mammalian physiology protein phosphorylation angiogenesis host specificity secondary metabolism endogenous substrate low aerobic capacity glucose intolerance insulin receptor insulin sensitivity clinical physiology adaptive immune system biological function cancer genetics mitogenic action high-fat diet differential effects receptor-mediated insulin endocytosis null deletion artificial selection cardiovascular risk factors redefined nomenclature fatty liver disease metabolic remodeling molecular cancer cancer research lipid synthesis molecular metabolism

Notable Scholarly Works

Notable Federal Grants

Collaborators

12411 Trends in Metabolic Dysfunction-Associated Steatotic Liver Disease(Masld) by Race/Ethnicity: Data From Nhanes 1988 to 2018. Journal of the Endocrine Society (2024)

M ShaheenK SchrodeD PanS M NajjarT C Friedman

public healthmedical anthropologydigestive diseasesfatty liver diseaseliver transplantationepidemiologyendocrinologymetabolic syndromevascular biologyliver diseaseobesitymetabolic disordershepatotoxicityacute liver failureglobal healthhepatologyethnicityliver physiology

Carcinoembryonic Antigen‐Related Cell Adhesion Molecule 1 in Cancer: Blessing or Curse?. European Journal of Clinical Investigation (2024)

Lisa GötzUwe RueckschlossSonia M. NajjarSüleyman ErgünFlorian Kleefeldt

immunologytumor targetingmolecular cancercancer immunosurveillanceclinical investigationcancer immunotherapycancer discoverymolecular biologyclinical researchoncogenescancer cellstumor microenvironmentcell adhesioncancer biologyadhesiontumor biologytumor innervationcell biology

Cell-Specific Regulation of Insulin Action and Hepatic Fibrosis by Ceacam1. Metabolism and Target Organ Damage (2024)

Basel G AldroubiJohn A NajjarTya S YoussefCarl E RizkBasil A M AbuamrehKarl AramouniHilda E GhadiehSonia M Najjar

cell signalingmetabolismliver physiologycell biologyendocrinologyinsulin actionsignal transductioninflammationcell metabolisminsulin signalingcellular physiologyliver diseasecell regulationfibrosishepatic fibrosisfree radical biologysystems biologyredox biologymolecular biologycell-specific regulationgene regulation

Conditional Deletion of Ceacam1 Causes Hepatic Stellate Cell Activation. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Harrison T. MuturiHilda E. GhadiehSuman AsallaSumona G. LesterStefaan VerhulstHannah L. StankusSobia ZaidiRaziyeh AbdolahipourGetachew D. BelewLeo A van GrunsvenScott L. FriedmanRobert F. SchwabeTerry D. HindsSonia M. Najjar

immunologypharmacologyconditional deletioncell signalingmolecular biologyhepatologysignal transduction

Conditional Deletion of Ceacam1 in Hepatic Stellate Cells Causes Their Activation. Molecular Metabolism (2024)

Harrison T. MuturiHilda E. GhadiehSuman AsallaSumona G. LesterGetachew D. BelewSobia ZaidiRaziyeh AbdolahipourAbhishek P. ShresthaAgnes O. PortuphyHannah L. StankusRaghd Abu HelalStefaan VerhulstSergio DuarteAli ZarrinparLeo A. van GrunsvenScott L. FriedmanRobert F. SchwabeTerry D. HindsSivarajan KumarasamySonia M. Najjar

conditional deletionsystems biologycell signalingmolecular and cellular biologyvascular biologyliver diseasemolecular cell biologymolecular metabolismhepatotoxicityhost factorsmolecular biologyhepatic stellate cellshepatologymetabolismliver physiologybiochemistryinflammation

Current Investigation of Carcinoembryonic Antigen Cell Adhesion Molecule ( Ceacam ) Biology Summary of the 32Nd Cea Symposium: 20–23 September 2024. WüRzburg, Germany. European Journal of Clinical Investigation (2024)

James M. FleckensteinSonia M. NajjarWolfgang ZimmermannChristof R. HauckQuynh NguyenRaquel Mejias‐LuqueAsima BhattacharyyaAlex J. McCarthyArup SarkarMaciej KujawskiAnastasia KonievaFadi ElyateemIrina Kube‐GolovinGunther WennemuthRobert KammererKeith M. SkubitzJohn E. ShivelyKenneth J. DeryGabriela DvekslerLisa GötzFlorian KleefeldtSüleyman Ergün

immunologycurrent investigationkey sitebiology summarymolecular biologycell adhesionclinical investigationadhesioncell biology

Insights Into Circulating Ceacam1 in Insulin Clearance and Disease Progression: Evidence From the Portuguese Prevadiab2 Study. European Journal of Clinical Investigation (2024)

Rita S. PatarrãoMaria João MenesesHilda E. GhadiehLaura HerreraSérgio DuarteRogério T. RibeiroJoão F. RaposoVerena SchmittBernhard B. SingerAmalia GastaldelliCarlos Penha‐GonçalvesSonia M. NajjarM. Paula Macedo

diabetesepidemiologyclinical evidencediabetes managementinsulin clearancediabetes researchpublic healthdiabetes therapieshematologybiomarkersinsulin signalingdiabetes epidemiologymetabolic syndromecardiovascular diseasediabetes mellitusimmunologyclinical researchdiabetic medicineclinical investigation

Insulin Increases Type I Collagen Synthesis in Hepatic Stellate Cells via α5β1 Integrin. Metabolism and Target Organ Damage (2024)

Milan DodigMin LiSrinivasan DasarathySivarajan KumarasamyTakhar KasumovSonia M. NajjarArthur J McCullough

insulin signalinghepatic stellate cellsmetabolisminsulin increasesbiochemistry

Loss of Ceacam1 in Hepatocytes Causes Hepatic Fibrosis. European Journal of Clinical Investigation (2024)

Sobia ZaidiSuman AsallaHarrison T. MuturiLucia RussoRaziyeh AbdolahipourGetachew Debas BelewMaria Benitez IglesiasMary FeraudoLensay LeonEnoch KuoXiuli LiuSivarajan KumarasamyHilda E. GhadiehCara Gatto‐WeisAli ZarrinparSergio DuarteSonia M. Najjar

immunologyfibrosispharmacologyhematologyclinical reviewsexperimental medicinenephrologyclinical chemistryclinical evidenceclinical biochemistryclinical pathologyliver diseaseclinical researchhepatologyrespiratory medicineclinical investigationhealth sciencestranslational medicine

Mechanism and Function of Ceacam1 Splice Isoforms. European Journal of Clinical Investigation (2024)

Kenneth J. DerySonia M. NajjarNicole BeaucheminJohn E. ShivelyJerzy W. Kupiec‐Weglinski

gene expressiontranscription (biology)geneticsmolecular biologysplicing variantclinical investigation

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J. Najjar

Professor

Ohio University

Affiliations

Heritage College of Osteopathic Medicine

Biomedical Sciences

J. Najjar is currently serving as a Biomedical Sciences Professor at Ohio University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

J. Najjar

Ohio University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

12411 Trends in Metabolic Dysfunction-Associated Steatotic Liver Disease(Masld) by Race/Ethnicity: Data From Nhanes 1988 to 2018. Journal of the Endocrine Society (2024)

M ShaheenK SchrodeD PanS M NajjarT C Friedman

Carcinoembryonic Antigen‐Related Cell Adhesion Molecule 1 in Cancer: Blessing or Curse?. European Journal of Clinical Investigation (2024)

Lisa GötzUwe RueckschlossSonia M. NajjarSüleyman ErgünFlorian Kleefeldt

Cell-Specific Regulation of Insulin Action and Hepatic Fibrosis by Ceacam1. Metabolism and Target Organ Damage (2024)

Basel G AldroubiJohn A NajjarTya S YoussefCarl E RizkBasil A M AbuamrehKarl AramouniHilda E GhadiehSonia M Najjar

Conditional Deletion of Ceacam1 Causes Hepatic Stellate Cell Activation. bioRxiv (Cold Spring Harbor Laboratory) (2024)

immunologypharmacologyconditional deletioncell signalingmolecular biologyhepatologysignal transduction

Conditional Deletion of Ceacam1 in Hepatic Stellate Cells Causes Their Activation. Molecular Metabolism (2024)

immunologycurrent investigationkey sitebiology summarymolecular biologycell adhesionclinical investigationadhesioncell biology

Insights Into Circulating Ceacam1 in Insulin Clearance and Disease Progression: Evidence From the Portuguese Prevadiab2 Study. European Journal of Clinical Investigation (2024)

Insulin Increases Type I Collagen Synthesis in Hepatic Stellate Cells via α5β1 Integrin. Metabolism and Target Organ Damage (2024)

Milan DodigMin LiSrinivasan DasarathySivarajan KumarasamyTakhar KasumovSonia M. NajjarArthur J McCullough

insulin signalinghepatic stellate cellsmetabolisminsulin increasesbiochemistry

Loss of Ceacam1 in Hepatocytes Causes Hepatic Fibrosis. European Journal of Clinical Investigation (2024)

Mechanism and Function of Ceacam1 Splice Isoforms. European Journal of Clinical Investigation (2024)

Kenneth J. DerySonia M. NajjarNicole BeaucheminJohn E. ShivelyJerzy W. Kupiec‐Weglinski

gene expressiontranscription (biology)geneticsmolecular biologysplicing variantclinical investigation

1
2
3
4
5
15
10 / page

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