Nahum Puebla-Osorio

Nahum Puebla-Osorio is an Assistant Professor at The University of Texas MD Anderson Cancer Center. His research focuses on cancer immunotherapy, radiation oncology, and immunology, with particular emphasis on immune checkpoint inhibitors, cellular therapy, and tumor microenvironment interactions. Recent work explores immuno-metabolic interactions in cancer progression, mechanisms by which cancer cells evade ferroptosis via fatty acid binding proteins, and synergistic low-dose radiation to enhance immunotherapy efficacy in metastatic melanoma. He has also investigated nanomechanical signatures predicting response to combination immunotherapy and radiation, and B-cell receptor/AKT signaling in diffuse large B-cell lymphoma. His publications span Frontiers in Immunology, Molecular Cancer, and Blood, integrating AI and animal models for precision oncology.