Faculty

Institution

Unit

Venue

Minglei Bian

Assistant Professor

Eastern Virginia Medical School

Affiliations

Doctoral Programs

Eastern Virginia Medical School, Research

Education

Minglei Bian is currently serving as a Doctoral Programs Assistant Professor at Eastern Virginia Medical School.

Honors

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Experiences

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Education

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Minglei Bian

Eastern Virginia Medical School

Assistant Professor

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cancer research cancer biology tumor biology medicinal research oncogenes oncology molecular cancer metastasis oncogenic agent enzyme inhibition cancer care signaling pathways health sciences breast cancer pancreatic cancer cancer genetics cancer treatment cell regulation cancer cells cancer management anti-cancer agents cancer growth focal adhesion immunology medicine developmental biology biomarkers computational biology machine learning cancer imaging cancer discovery cell death molecular cell biology leukemia cellular therapy genome biology surgical oncology breast oncology prognosis prognostic biomarkers pathway analysis hyperparameter estimation apoptosis cancer genomics receptor tyrosine kinases tumor targeting medical genetics cancer prevention hepatocellular carcinoma localized excited state ras pathway biomarkers metastatic breast cancer core principles molecular insights trigger timing random search hyperparameter minimal ovarian stimulation cancer cell dissemination oncogenic k-ras addiction cellular stress human cancer cells late-stage tumor growth triple-negative breast cancer siah-dependent proteolytic machinery control metastasis infertility reproductive health cancer risk urology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Optimizing Trigger Timing in Minimal Ovarian Stimulation for in Vitro Fertilization Using Machine Learning Models With Random Search Hyperparameter Tuning. Computers in Biology and Medicine (2024)

Nayeli Areli Pérez-PadillaRodolfo Garcia-SanchezOmar AvalosJorge GálvezMinglei BianLiang YuYimin ShuMing FengFrank D Yelian

computational biologyhyperparameter estimationtrigger timingrandom search hyperparameterbiologyminimal ovarian stimulationmachine learning

A New Strategy to Control and Eradicate “Undruggable” Oncogenic K-Ras-Driven Pancreatic Cancer: Molecular Insights and Core Principles Learned From Developmental and Evolutionary Biology. Cancers (2018)

Robert Van SciverMichael LeeCaroline LeeAlex LafeverElizaveta SvyatovaKevin KandaAmber CollierLauren Siewertsz van ReesemaAngela Tang-TanVasilena ZhelevaMonicah BwayiMinglei BianRebecca SchmidtLynn MatrisianGloria PetersenAmy Tang

oncogenescore principlestumor biologymolecular cancerdevelopmental biologycancer researchcancer discoverypancreatic cancermolecular biologyoncogenic agentmolecular insightscancer geneticsoncologycancer biology

Abstract 3498: Increased Cellular Stress and Apoptosis Induced by Anti-Siah2 Therapy in Human Cancer Cells With Oncogenic K-Ras Addiction. Cancer Research (2016)

Monicah M. NjoguCaroline LeeJamie EisnerMinglei BianRobert VansciverAmy H. Tang

oncogenic k-ras addictionapoptosiscell biologycancer researchcellular stresshuman cancer cellscancer treatmentoncology

Abstract 5049: Siah2 E3 Ligase Targets Lim-Domain Proteins for Degradation to Modulate Focal Adhesion and Cell Motility. Cancer Research (2016)

Minglei BianYang LiaoMonicah NjoguRebecca SchmidtRie TakahashiZandra WaltonAmy H. Tang

cancer researchmolecular biologycancer biologyfocal adhesion

Siah and Egfr, Two Ras Pathway Biomarkers, Are Highly Prognostic in Locally Advanced and Metastatic Breast Cancer. EBioMedicine (2016)

Lauren L. Siewertsz van ReesemaVasilena ZhelevaJanet S. WinstonRick J. JansenCarolyn F. O’ConnorAndrew J. IsbellMinglei BianRui QinPatricia T. BassettVirginia J. HinsonKimberly A. DorschBrad W. KirbyRobert E. Van SciverAngela M. Tang-TanElizabeth A. HardenDavid Z. ChangCynthia A. AllenRoger R. PerryRichard A. HoeferAmy H. Tang

breast oncologyprognosisprognostic biomarkerstumor biologycancer biologyras pathway biomarkersimmunologymedicinal researchcancer imagingcancer researchpathway analysismedicinemetastatic breast cancerbiomarkershealth sciencesoncologybreast cancer

Abstract 4366: Inhibition of Late-Stage Tumor Growth of Human Pancreatic and Triple-Negative Breast Cancer by Blocking the Most Downstream “Gatekeeper” Signaling Module, Siah E3 Ligase, in the Oncogenic Erbb/ K-Ras Signaling Pathway. Cancer Research (2015)

Minglei BianVasilena ZhelevaXiaofei GaoJustin OdangaMonica NjoguZena UrbanBruce KnudsenRichard A. HoeferRoger R. PerryAmy H. Tang

pharmacologylate-stage tumor growthbreast cancertumor biologycell signalingcell biologyenzyme inhibitioncancer researchmolecular biologytriple-negative breast canceroncogenesmedicinal researchmolecular cancercell regulationcancer managementcancer carecancer biologyclinical researchcancer geneticscancer genomics

Abstract B70: Developing a New and Potent Anti-K-Ras Strategy by Inhibiting Siah E3 Ligase, the Most Downstream “Gatekeeper” in the Oncogenic K-Ras Signal Pathway, to Block Well-Established Pancreatic Tumor Growth. Cancer Research (2015)

Vasilena ZhelevaMinglei BianXiaofei GaoJustin J. OdangaMonicah M. NjoguZena M. UrbanBruce E. KnudsenRichard A. HoeferRoger R. PerryAmy H. Tang

anti-cancer agentscarcinogenesispharmacologypotent anti-k-ras strategytumor biologymolecular biologyhepatocellular carcinomahealth sciencesoncogenesmedicinal researchmolecular cancerprostate canceroncogenic agentcell regulationcancer caresarcomacancer growthclinical researchenzyme inhibition

Abstract 4442: Inhibition of Siah E3 Ligase Function Leads to Increased Cell Death in Metastatic Human Cancer Cells. Cancer Research (2014)

Zena M. UrbanLauren van ReesemaMinglei BianThomas C. SmyrkGloria PetersonAmy H. Tang

metastasiscell deathcell biologycancer researchcancer biology

Abstract A26: Attacking the Most Downstream “Gatekeeper,” the Siah-Dependent Proteolytic Machinery, in the Oncogenic Erbb/K-Ras Signaling Pathway to Block Tumorigenesis and Control Metastasis in Human Cancer. Molecular Cancer Research (2014)

Minglei BianYang LiaoVasilena ZhelevaZena UrbanMonicah NjoguJustin J. OdangaAndrew J. IsbellRoger R. PerryRichard A. HoeferThomas C. SmyrkGloria M. PetersenAmy H. Tang

proteomicsanti-cancer agentspharmacologycell and molecular biologytumor biologycell biologycancer researchmolecular biologysiah-dependent proteolytic machinerycancer cellsoncogenesreceptor tyrosine kinasesmolecular canceroncogenic agentcell regulationcontrol metastasistumor targetingmolecular medicinehuman cancermolecular cell biologyleukemia

Inhibition of Established Pancreatic and Triple Negative Breast Tumor Growth by Blocking the Most Downstream Signaling Module, Siah, in the Oncogenic Erbb/K-Ras Signaling Pathway. Journal of the American College of Surgeons (2014)

Vasilena ZhelevaMinglei BianXiaofei GaoJustin OdangaZena UrbanMonicah NjoguBruce KnudsenRichard A. HoeferRoger R. PerryAmy H. Tang

surgical oncologypharmacologybreast cancersurgerycell signalingcancer researchpancreatic cancercancer cellsoncogenesmedicinal researchsignaling pathwaysoncogenic agentcancer biologyneurologymetastasisdownstream signaling modulecancer growthenzyme inhibitiononcology

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Minglei Bian

Assistant Professor

Eastern Virginia Medical School

Affiliations

Doctoral Programs

Eastern Virginia Medical School, Research

Education

Minglei Bian is currently serving as a Doctoral Programs Assistant Professor at Eastern Virginia Medical School.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Minglei Bian

Eastern Virginia Medical School

Assistant Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Optimizing Trigger Timing in Minimal Ovarian Stimulation for in Vitro Fertilization Using Machine Learning Models With Random Search Hyperparameter Tuning. Computers in Biology and Medicine (2024)

Nayeli Areli Pérez-PadillaRodolfo Garcia-SanchezOmar AvalosJorge GálvezMinglei BianLiang YuYimin ShuMing FengFrank D Yelian

computational biologyhyperparameter estimationtrigger timingrandom search hyperparameterbiologyminimal ovarian stimulationmachine learning

Abstract 3498: Increased Cellular Stress and Apoptosis Induced by Anti-Siah2 Therapy in Human Cancer Cells With Oncogenic K-Ras Addiction. Cancer Research (2016)

Monicah M. NjoguCaroline LeeJamie EisnerMinglei BianRobert VansciverAmy H. Tang

oncogenic k-ras addictionapoptosiscell biologycancer researchcellular stresshuman cancer cellscancer treatmentoncology

Abstract 5049: Siah2 E3 Ligase Targets Lim-Domain Proteins for Degradation to Modulate Focal Adhesion and Cell Motility. Cancer Research (2016)

Minglei BianYang LiaoMonicah NjoguRebecca SchmidtRie TakahashiZandra WaltonAmy H. Tang

cancer researchmolecular biologycancer biologyfocal adhesion

Siah and Egfr, Two Ras Pathway Biomarkers, Are Highly Prognostic in Locally Advanced and Metastatic Breast Cancer. EBioMedicine (2016)

Minglei BianVasilena ZhelevaXiaofei GaoJustin OdangaMonica NjoguZena UrbanBruce KnudsenRichard A. HoeferRoger R. PerryAmy H. Tang

Vasilena ZhelevaMinglei BianXiaofei GaoJustin J. OdangaMonicah M. NjoguZena M. UrbanBruce E. KnudsenRichard A. HoeferRoger R. PerryAmy H. Tang

Abstract 4442: Inhibition of Siah E3 Ligase Function Leads to Increased Cell Death in Metastatic Human Cancer Cells. Cancer Research (2014)

Zena M. UrbanLauren van ReesemaMinglei BianThomas C. SmyrkGloria PetersonAmy H. Tang

metastasiscell deathcell biologycancer researchcancer biology

Minglei BianYang LiaoVasilena ZhelevaZena UrbanMonicah NjoguJustin J. OdangaAndrew J. IsbellRoger R. PerryRichard A. HoeferThomas C. SmyrkGloria M. PetersenAmy H. Tang

Vasilena ZhelevaMinglei BianXiaofei GaoJustin OdangaZena UrbanMonicah NjoguBruce KnudsenRichard A. HoeferRoger R. PerryAmy H. Tang

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