Faculty

Institution

Unit

Venue

Min Gyu Lee

Professor

The University of Texas MD Anderson Cancer Center

Affiliations

Department Of Epigenetics And Molecular Carcinogenesis

Department Of Molecular And Cellular Oncology

Min Gyu Lee is currently serving as an Epigenetics And Molecular Carcinogenesis Professor at The University of Texas Md Anderson Cancer Center.

Honors

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Experiences

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Education

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Min Gyu Lee

The University of Texas MD Anderson Cancer Center

Professor

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molecular biology cell biology genetics cancer biology gene expression cancer research tumor biology oncogenes epigenetics cancer genetics biochemistry molecular cell biology cancer cells medicinal research cell signaling cell regulation chromatin molecular genetics epigenetic changes gene regulation molecular regulation molecular and cellular biology stem cell research molecular cancer thoracic oncology tumor suppressors protein science transcription regulation insect molecular biology structural molecular biology nucleic acids respiratory medicine mammalian biology gene function chromatin remodeling signaling pathways yeast medical genetics essential role experimental medicine clinical investigation natural product research chromosome biology functional modification protein chemistry protein function protein synthesis cellular biology clinical medicine molecular catalysis developmental genetics heme signaling histocompatibility phytochemistry protein genetics protein expression gene structure novel therapies oncogenic agent non-coding rna melanoma nonselective antidepressive medications polycomb-like protein deacetylase enzymes functional interplay histone demethylase glycolytic vulnerability tandem phd tumor suppressor genes metastasis-linked genes rna polymerase ii trithorax-group gene bivalent promoters tumor suppression pten self-regulates igf signaling

Notable Scholarly Works

Notable Federal Grants

Collaborators

Actin Dysregulation Induces Neuroendocrine Plasticity and Immune Evasion: A Vulnerability of Small Cell Lung Cancer. Nature Communications (2025)

lung cancertumor biologyactin dysregulation inducescytoskeletoncancer biologyimmune evasioncell biologycell signalingcancer cellsimmunologycell deathbronchial neoplasm

Figure S1 From the Lung Cancer Autochthonous Model Gene Expression Database Enables Cross-Study Comparisons of the Transcriptomic Landscapes Across Mouse Models. (2025)

Ling CaiFangjiang WuQinbo ZhouYing GaoBo YaoRalph J. DeBerardinisGeorge K. Acquaah-MensahVassilis AidinisJennifer E. BeaneShyam BiswalTing ChenCarla P. Concepcion-CrisolBarbara M. GrünerDeshui JiaRobert A. JonesJonathan M. KurieMin Gyu LeePer LindahlYonathan LissanuCorina LorzDavid MacPhersonRosanna MartinelliPawel K. MazurSarah A. MazzilliShinji MiiHerwig P. MollRoger A. MooreheadEdward E. MorriseySheng Rong NgMatthew G. OserArun R. PandiriCharles A. PowellGiorgio RamadoriMirentxu SantosEric L. SnyderRocio SotilloKang-Yi SuTetsuro TakiKekoa TaparraPhuoc T. TranYifeng XiaJ. Edward van VeenMonte M. WinslowGuanghua XiaoCharles M. RudinTrudy G. OliverYang XieJohn D. Minna

lung cancercancer genomicsgeneticsbioinformaticsoncogenessystems biologytranscriptomegene expression profilingfigure s1cancer discoverycancer genetics

Heterozygous Kmt2D Loss Diminishes Enhancers to Render Medulloblastoma Cells Vulnerable to Combinatory Inhibition of Lsd1 and Oxphos. Cell Reports (2025)

tumor biologycancer biologycell biologycancer cellsoncogenestherapeutic targetsmolecular biology

Kap1 Promotes Gastric Adenocarcinoma Progression by Activating Hippo/Yap1 Signaling via Binding to Hnrnpab. Cancer Letters (2025)

Shumei SongYibo FanGengyi ZouLongfei HuoJanani KumarYuan LiRuiping WangEnyu DaiJiankang JinAiling W ScottShan ShaoMelissa Pool PizziJody V VykoukalHiryuki KatayamaSamir HanashGeorge A CalinXing ZhangMin Gyu LeeZhenning WangYuan-Hung LoQiong GanRebecca E WatersFeng YinLinghua WangXiaodong ChengJaffer A AjaniShilpa S Dhar

cancer immunotherapytumor biologycancer researchoncologysystems biologycancer treatmentcancer discoverytumor microenvironmentdisease progressiongastric adenocarcinoma progressionmolecular cancergastrointestinal oncologytumoral pathologyimmunologymolecular gastroenterologysignaling pathwayscancer cellsoncogenespathology

Kdm4A Promotes Nepc Progression Through Regulation of Myc Expression. Cancer Letters (2025)

cell regulationmolecular cell biologycell biologycell signalingoncogenestranscription factorsnepc progressionsignal transduction

Kmt2D Temporally Activates Neuronal Transcriptional Factor Genes to Mediate Cerebellar Granule Cell Differentiation. Science Advances (2025)

developmental biologycellular differentiationmolecular neuroscienceneuronscellular neurobiologycell biologycell signalingmolecular cell biologytranscription factorsmolecular neurobiologycellular physiology

Abstract 1730: Unraveling the Oncogenic Potential of Kdm2A With Gastric Organoids. Cancer Research (2024)

molecular gastroenterologygastric organoidsgastrointestinal peptide hormonemolecular physiologyoncogenic potentialcell biologypharmacologyabstract 1730molecular pharmacologycarcinogenesisgastrointestinal pharmacologymolecular medicinepathology

A Lung Cancer Mouse Model Database. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Ling CaiYing GaoRalph J. DeBerardinisGeorge Acquaah-MensahVassilis AidinisJennifer E. BeaneShyam BiswalTing ChenCarla P. Concepcion-CrisolBarbara M. GrünerDeshui JiaRobert JonesJonathan M. KurieMin Gyu LeePer LindahlYonathan LissanuMaria Corina Lorz LopezRosanna MartinelliPawel K. MazurSarah A. MazzilliShinji MiiHerwig MollRoger MooreheadEdward E. MorriseySheng Rong NgMatthew G. OserArun R. PandiriCharles A. PowellGiorgio RamadoriMirentxu Santos LafuenteEric SnyderRocio SotilloKang-Yi SuTetsuro TakiKekoa TaparraYifeng XiaEd van VeenMonte M. WinslowGuanghua XiaoCharles M. RudinTrudy G. OliverYang XieJohn D. Minna

biomedical informaticslung cancertumor biologygeneticsmolecular diagnosticscancer genomicscomparative analysiscancer researchbioinformaticscell biologyoncogenesgenetic aberrationssystems biologycomputational biologygene expression profilingcancer geneticstumor heterogeneity

Abstract 3567: Cancer-Epigenetic Mouse Models for Medulloblastoma. Cancer Research (2023)

tumor biologyepigeneticscancer biologycell biologycancer discovery

Data From Cancer Stem Cells, Not Bulk Tumor Cells, Determine Mechanisms of Resistance to Smo Inhibitors. (2023)

Joshy GeorgeYaohui ChenNourhan AbdelfattahKeiko YamamotoThomas D. GallupScott I. AdamsonBrad RybinskiAnuj SrivastavaParveen KumarMin Gyu LeeDavid S. BaskinWen JiangJong Min ChoiWilliam FlavahanJeffrey H. ChuangBetty Y.S. KimJiaqiong XuSung Yun JungKyuson Yun

cancer immunotherapyoncologyradiation oncologycancer researchcancer biologydrug resistancebulk tumor cellsdata sciencepharmacologycancer treatmentdetermine mechanismscancer stem cellsdrug discoverymedicinal research

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Min Gyu Lee

Professor

The University of Texas MD Anderson Cancer Center

Affiliations

Department Of Epigenetics And Molecular Carcinogenesis

Department Of Molecular And Cellular Oncology

Min Gyu Lee is currently serving as an Epigenetics And Molecular Carcinogenesis Professor at The University of Texas Md Anderson Cancer Center.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Min Gyu Lee

The University of Texas MD Anderson Cancer Center

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Actin Dysregulation Induces Neuroendocrine Plasticity and Immune Evasion: A Vulnerability of Small Cell Lung Cancer. Nature Communications (2025)

lung cancertumor biologyactin dysregulation inducescytoskeletoncancer biologyimmune evasioncell biologycell signalingcancer cellsimmunologycell deathbronchial neoplasm

Figure S1 From the Lung Cancer Autochthonous Model Gene Expression Database Enables Cross-Study Comparisons of the Transcriptomic Landscapes Across Mouse Models. (2025)

lung cancercancer genomicsgeneticsbioinformaticsoncogenessystems biologytranscriptomegene expression profilingfigure s1cancer discoverycancer genetics

Heterozygous Kmt2D Loss Diminishes Enhancers to Render Medulloblastoma Cells Vulnerable to Combinatory Inhibition of Lsd1 and Oxphos. Cell Reports (2025)

tumor biologycancer biologycell biologycancer cellsoncogenestherapeutic targetsmolecular biology

Kap1 Promotes Gastric Adenocarcinoma Progression by Activating Hippo/Yap1 Signaling via Binding to Hnrnpab. Cancer Letters (2025)

Kdm4A Promotes Nepc Progression Through Regulation of Myc Expression. Cancer Letters (2025)

cell regulationmolecular cell biologycell biologycell signalingoncogenestranscription factorsnepc progressionsignal transduction

Kmt2D Temporally Activates Neuronal Transcriptional Factor Genes to Mediate Cerebellar Granule Cell Differentiation. Science Advances (2025)

Abstract 1730: Unraveling the Oncogenic Potential of Kdm2A With Gastric Organoids. Cancer Research (2024)

A Lung Cancer Mouse Model Database. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Abstract 3567: Cancer-Epigenetic Mouse Models for Medulloblastoma. Cancer Research (2023)

tumor biologyepigeneticscancer biologycell biologycancer discovery

Data From Cancer Stem Cells, Not Bulk Tumor Cells, Determine Mechanisms of Resistance to Smo Inhibitors. (2023)

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