Faculty

Institution

Unit

Venue

Micquel Downs

Louisiana State University Health Sciences Center, New Orleans

Affiliations

Cytogenetics Laboratory

Departments Of Microbiology And Immunology, Genetics And Medicine

Louisiana State University Health Sciences Center, New Orleans

NoneMicquel Downs is currently serving as a Cytogenetics Laboratory faculty at Louisiana State University Health Sciences Center, New Orleans.

Honors

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Experiences

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Education

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Micquel Downs

Louisiana State University Health Sciences Center, New Orleans

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protein science molecular biology protein function biochemistry molecular motors cytoskeleton enzymes molecular biophysics molecular cell biology biological chemistry biochemical sciences cell biology molecular and cellular biology cell division biophysical chemistry protein structure cellular biochemistry biomolecular structure mitophagy organelle dynamics inter-organelle interactions chemistry organic process research biomolecules biological macromolecules molecular neurodegeneration bioenergetics molecular informatics structural molecular biology structure-function enzyme kinetics biocatalysis enzyme catalysis conformational studies proton-coupled electron transfer proton transfer biomolecular interactions protein modeling protein bioinformatics multi-protein assembly mitotic spindle zika protease cleavage water use kinesin catalysis abstract 1858 abstract 2401 conformational changes allosteric uncoupling microtubule depolymerase activity distinct mitotic defects human kinesin-5 second proton transfer zundel cation polymorphic interruption molecular allosteric pathways

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 1858: Active and Allosteric Site Evolution Directs Ordered Water Use in Kinesin Catalysis. Journal of Biological Chemistry (2023)

biophysical chemistrywater usestructure-function enzyme kineticsenzymesbiocatalysiskinesin catalysisabstract 1858enzyme catalysischemistryorganic process researchbiomoleculesbiochemical sciencesbiochemistry

Abstract 2401: Applying the Brakes: Understanding the Role of Conformational Changes in Kinesin-5. Journal of Biological Chemistry (2023)

molecular motorsmolecular biophysicsbiophysicsbiological macromoleculesprotein functionabstract 2401protein scienceprotein structureconformational studiesmolecular biologybiomolecular structurebiochemical sciencesconformational changesbiochemistry

Polymorphic Interruption of Molecular Allosteric Pathways in Mitotic Kinesin-5: Comparison of Experiment and Algorithmic Prediction. Biophysical Journal (2022)

protein functionprotein structurepolymorphic interruptionbiological chemistrycomputational biologymolecular informaticsbiochemistrybiomolecular interactionsmolecular allosteric pathwayscytoskeletonmolecular cell biologybiomolecular structureprotein modelingprotein scienceprotein foldingmolecular motorsmolecular biophysicsmitotic kinesin-5systems biologyprotein bioinformaticsmolecular biologystructural molecular biologymulti-protein assembly

Inter-Organelle Interactions Between the Er and Mitotic Apparatus Facilitates Zika Protease Cleavage of Human Kinesin-5 and Contributes to Distinct Mitotic Defects. Biophysical Journal (2021)

distinct mitotic defectsprotein functioncytoskeletoncell signalingmolecular and cellular biologycell divisionmolecular cell biologymolecular biologymolecular neurodegenerationbiological chemistrymitophagyinter-organelle interactionsorganelle dynamicsprotein sciencehuman kinesin-5cellular biochemistrycell biology

Inter-Organelle Interactions Between the Er and Mitotic Spindle Facilitates Zika Protease Cleavage of Human Kinesin-5 and Results in Mitotic Defects. iScience (2021)

mitotic spindlemolecular motorsprotein functioncytoskeletonzika protease cleavagemolecular and cellular biologycell divisionmolecular cell biologymolecular biologybiological chemistrymitophagyinter-organelle interactionsorganelle dynamicsprotein sciencecellular biochemistrycell biology

Kinesin Atp Hydrolysis Requires Proton Tunneling Within the Zundel Cation and a Second Proton Transfer. Biophysical Journal (2021)

molecular motorsbiophysicsmolecular biophysicsbiophysical chemistrysecond proton transfercytoskeletonprotein scienceproton-coupled electron transferenzymesmolecular biologybiochemical sciencesbioenergeticsproton transferbiochemistryzundel cation

Allosteric Uncoupling of Microtubule Depolymerase Activity From Motility in Human Kinesin‐5. The FASEB Journal (2020)

Micquel DownsCatherine KimElizabeth KimLiqiong LiuSreeja ParameswaranSunyoung KimEdward Wojcik

biomechanicskinesiologyprotein functionallosteric uncouplinggeneticsmicrotubule depolymerase activityenzymesmembrane biologystructural biologyprotein scienceprotein engineeringneuroscience

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Micquel Downs

Louisiana State University Health Sciences Center, New Orleans

Affiliations

Cytogenetics Laboratory

Departments Of Microbiology And Immunology, Genetics And Medicine

Louisiana State University Health Sciences Center, New Orleans

NoneMicquel Downs is currently serving as a Cytogenetics Laboratory faculty at Louisiana State University Health Sciences Center, New Orleans.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Micquel Downs

Louisiana State University Health Sciences Center, New Orleans

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 1858: Active and Allosteric Site Evolution Directs Ordered Water Use in Kinesin Catalysis. Journal of Biological Chemistry (2023)

Abstract 2401: Applying the Brakes: Understanding the Role of Conformational Changes in Kinesin-5. Journal of Biological Chemistry (2023)

Polymorphic Interruption of Molecular Allosteric Pathways in Mitotic Kinesin-5: Comparison of Experiment and Algorithmic Prediction. Biophysical Journal (2022)

Inter-Organelle Interactions Between the Er and Mitotic Apparatus Facilitates Zika Protease Cleavage of Human Kinesin-5 and Contributes to Distinct Mitotic Defects. Biophysical Journal (2021)

Inter-Organelle Interactions Between the Er and Mitotic Spindle Facilitates Zika Protease Cleavage of Human Kinesin-5 and Results in Mitotic Defects. iScience (2021)

Kinesin Atp Hydrolysis Requires Proton Tunneling Within the Zundel Cation and a Second Proton Transfer. Biophysical Journal (2021)

Allosteric Uncoupling of Microtubule Depolymerase Activity From Motility in Human Kinesin‐5. The FASEB Journal (2020)

Micquel DownsCatherine KimElizabeth KimLiqiong LiuSreeja ParameswaranSunyoung KimEdward Wojcik

biomechanicskinesiologyprotein functionallosteric uncouplinggeneticsmicrotubule depolymerase activityenzymesmembrane biologystructural biologyprotein scienceprotein engineeringneuroscience

1
10 / page