Faculty

Institution

Unit

Venue

Michaela Kollisch-Singule

Upstate Medical University

Affiliations

Department Of Golisano Pediatrics

Norton College of Medicine

Department Of Surgery

Departments Of Pediatrics And Microbiology And Immunology

Department Of Surgery

Division Of Pediatric Surgery

Michaela Kollisch-Singule is a Senior Professor at Upstate Medical University, specializing in respiratory medicine, critical care, and applied physiology. Her research focuses on optimizing mechanical ventilation strategies for injured lungs, particularly through time-controlled adaptive ventilation (TCAV) and the role of expiratory duration in preventing atelectrauma. Her recent work, published in Proceedings of the National Academy of Sciences and Critical Care, introduces computational and inverse modeling approaches to reduce injurious power and personalize lung protection in ARDS. She also explores biomedical engineering applications, including antimicrobial hemostatic polymer foams. Her interdisciplinary collaborations bridge clinical intensive care with translational physiology and resuscitation science.

Honors

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Experiences

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Education

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Michaela Kollisch-Singule

Upstate Medical University

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respiratory medicine critical care ventilation physiology medicine intensive care applied physiology biomedical engineering resuscitation pulmonary circulation ventilator-induced lung injury patient safety inflammation thoracic surgery respiration (physiology) exercise physiology acute care trauma cardiology experimental medicine human physiology time-controlled adaptive ventilation injured lung hospital medicine injury prevention cell death intensive care nursing pulmonary care neonatology clinical physiology mechanical circulatory support acute lung injury biomechanical engineering controlled release biomedical analysis medicinal research critical emergency medicine acute care surgery acute medicine cardiopulmonary resuscitation lung transplantation mammalian physiology advanced lung disease pulmonary pharmacology mechanical breath profile lung injury respiratory mechanics mechanical ventilation dynamic strain high airway pressure circulatory physiology thoracic oncology cellular physiology molecular physiology digestive diseases perioperative monitoring continuous monitoring translational physiology stabilization (medicine) interventional pulmonology gene delivery lung deposition porcine disease digestive tract pediatric surgery preterm birth veterinary physiology pediatric emergency medicine pediatric heart disease pediatric lung diseases broken lung dynamic alveolar heterogeneity extrapulmonary lung injury two-hit porcine model electroporation-mediated gene delivery ventilation-induced lung injury

Notable Scholarly Works

Notable Federal Grants

Collaborators

Computationally-Directed Mechanical Ventilation in a Porcine Model of Ards. Frontiers in Physiology (2025)

computational engineeringcomputational mechanicscomputational fluid dynamicsmodeling and simulationventilationnumerical simulationsporcine modelengineering

CORRECTION: Atelectrauma Can Be Avoided If Expiration is Sufficiently Brief: Evidence From Inverse Modeling and Oscillometry During Airway Pressure Release Ventilation. Critical Care (2025)

Jason H. T. BatesDavid W. KaczkaMichaela Kollisch‑SinguleGary F. NiemanDonald P. Gaver

medicinecritical careintensive careanesthesiologyinverse modeling

Mechanical Ventilation Energy Analysis: Recruitment Focuses Injurious Power in the Ventilated Lung. Proceedings of the National Academy of Sciences (2025)

respiration (physiology)ventilated lungkinesiologyapplied physiologyventilationrespiratory medicinecritical careinterstitial lung diseaseinjurious powercardiovascular fitnesslung transplantation

Toward Optimal Mechanical Ventilation of the Injured Lung: The Role of Expiratory Duration. Critical Care (2025)

injured lungpulmonary circulationemergency medicineexpiratory durationtraumaventilationrespiratory medicineintensive carecritical careinterstitial lung disease

Effects of Lung Injury and Abdominal Insufflation on Respiratory Mechanics and Lung Volume During Time-Controlled Adaptive Ventilation. Respiratory Care (2024)

Harry RamcharranGregory WetmoreScott CooperJacob HerrmannAndrea Fonseca da CruzDavid W KaczkaJoshua SatalinSarah BlairPenny L AndrewsNader M HabashiGary F NiemanMichaela Kollisch-Singule

respiratory mechanicslung volumelung injurytime-controlled adaptive ventilationabdominal insufflationrespiratory medicine

Mechanical Ventilation Modality Influences Intratidal Gas and Blood Volume Dynamics: Experimental Demonstration of Dynamic Dual-Energy Ct. (2024)

J. HerrmannA. Fonseca CruzS.E. GerardK.B. GhaghadaM. Kollisch-SinguleG.F. NiemanE.A. HoffmanD.W. Kaczka

biomedical engineeringmechanical engineeringct scanmedical imagingcomputed tomographyventilationintratidal gasexperimental demonstrationrespiratory medicinemechanical ventilation modalitycritical carebiomedical imagingblood volume dynamicsdynamic dual-energy ct

Meconium Influences Pulmonary Short-Chain Fatty Acid Concentration in Porcine Meconium Aspiration Model. Biomedicine Hub (2024)

Harry RamcharranAuyon GhoshQinghe MengGuanqun LiEvan Skakel ChernovMark LutzHeidi M MansourJoshua SatalinSarah SatalinDonald P GaverJason H T BatesGary NiemanMichaela Kollisch-Singule

biomedical researchmedicineclinical researchpulmonary circulation

Time-Controlled Adaptive Ventilation (Tcav): A Personalized Strategy for Lung Protection. Respiratory Research (2024)

Hassan Al-KhalisyGary F. NiemanMichaela Kollisch-SingulePenny AndrewsLuigi CamporotaJoseph ShiberToni ManougianJoshua SatalinSarah BlairAuyon GhoshJacob HerrmannDavid W. KaczkaDonald P. GaverJason H. T. BatesNader M. Habashi

lung protectionventilationtime-controlled adaptive ventilationrespiratory medicinepersonalized strategycritical care

Vanillic Acid-Based Pro-Coagulant Hemostatic Shape Memory Polymer Foams With Antimicrobial Properties Against Drug-Resistant Bacteria. Acta Biomaterialia (2024)

Changling DuDavid Anthony FikhmanErnest Emmanuel ObengSevde Nur CanKatheryn Shi DongEden Tess LeavittLeo Vikram SaldanhaMichaela HallJoshua SatalinMichaela Kollisch-SinguleMary Beth B Monroe

biomedical engineeringdrug-resistant bacteriaantimicrobial propertiesbiomaterialsbiomaterials design

Mechanical Power and Ventilator-Induced Lung Injury: What Does Physics Have to Say?. American Journal of Respiratory and Critical Care Medicine (2023)

Jason H. T. BatesDavid W. KaczkaMichaela Kollisch-SinguleGary F. NiemanDonald P. Gaver

physicsmechanicsventilator-induced lung injurymechanical powerrespiratory medicinecritical careapplied physics

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Michaela Kollisch-Singule

Upstate Medical University

Affiliations

Department Of Golisano Pediatrics

Norton College of Medicine

Department Of Surgery

Departments Of Pediatrics And Microbiology And Immunology

Department Of Surgery

Division Of Pediatric Surgery

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Michaela Kollisch-Singule

Upstate Medical University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Computationally-Directed Mechanical Ventilation in a Porcine Model of Ards. Frontiers in Physiology (2025)

computational engineeringcomputational mechanicscomputational fluid dynamicsmodeling and simulationventilationnumerical simulationsporcine modelengineering

CORRECTION: Atelectrauma Can Be Avoided If Expiration is Sufficiently Brief: Evidence From Inverse Modeling and Oscillometry During Airway Pressure Release Ventilation. Critical Care (2025)

Jason H. T. BatesDavid W. KaczkaMichaela Kollisch‑SinguleGary F. NiemanDonald P. Gaver

medicinecritical careintensive careanesthesiologyinverse modeling

Mechanical Ventilation Energy Analysis: Recruitment Focuses Injurious Power in the Ventilated Lung. Proceedings of the National Academy of Sciences (2025)

respiration (physiology)ventilated lungkinesiologyapplied physiologyventilationrespiratory medicinecritical careinterstitial lung diseaseinjurious powercardiovascular fitnesslung transplantation

Toward Optimal Mechanical Ventilation of the Injured Lung: The Role of Expiratory Duration. Critical Care (2025)

injured lungpulmonary circulationemergency medicineexpiratory durationtraumaventilationrespiratory medicineintensive carecritical careinterstitial lung disease

Effects of Lung Injury and Abdominal Insufflation on Respiratory Mechanics and Lung Volume During Time-Controlled Adaptive Ventilation. Respiratory Care (2024)

Harry RamcharranGregory WetmoreScott CooperJacob HerrmannAndrea Fonseca da CruzDavid W KaczkaJoshua SatalinSarah BlairPenny L AndrewsNader M HabashiGary F NiemanMichaela Kollisch-Singule

respiratory mechanicslung volumelung injurytime-controlled adaptive ventilationabdominal insufflationrespiratory medicine

Mechanical Ventilation Modality Influences Intratidal Gas and Blood Volume Dynamics: Experimental Demonstration of Dynamic Dual-Energy Ct. (2024)

J. HerrmannA. Fonseca CruzS.E. GerardK.B. GhaghadaM. Kollisch-SinguleG.F. NiemanE.A. HoffmanD.W. Kaczka

Meconium Influences Pulmonary Short-Chain Fatty Acid Concentration in Porcine Meconium Aspiration Model. Biomedicine Hub (2024)

Harry RamcharranAuyon GhoshQinghe MengGuanqun LiEvan Skakel ChernovMark LutzHeidi M MansourJoshua SatalinSarah SatalinDonald P GaverJason H T BatesGary NiemanMichaela Kollisch-Singule

biomedical researchmedicineclinical researchpulmonary circulation

Time-Controlled Adaptive Ventilation (Tcav): A Personalized Strategy for Lung Protection. Respiratory Research (2024)

lung protectionventilationtime-controlled adaptive ventilationrespiratory medicinepersonalized strategycritical care

Vanillic Acid-Based Pro-Coagulant Hemostatic Shape Memory Polymer Foams With Antimicrobial Properties Against Drug-Resistant Bacteria. Acta Biomaterialia (2024)

Changling DuDavid Anthony FikhmanErnest Emmanuel ObengSevde Nur CanKatheryn Shi DongEden Tess LeavittLeo Vikram SaldanhaMichaela HallJoshua SatalinMichaela Kollisch-SinguleMary Beth B Monroe

biomedical engineeringdrug-resistant bacteriaantimicrobial propertiesbiomaterialsbiomaterials design

Mechanical Power and Ventilator-Induced Lung Injury: What Does Physics Have to Say?. American Journal of Respiratory and Critical Care Medicine (2023)

Jason H. T. BatesDavid W. KaczkaMichaela Kollisch-SinguleGary F. NiemanDonald P. Gaver

physicsmechanicsventilator-induced lung injurymechanical powerrespiratory medicinecritical careapplied physics

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10 / page