Faculty

Institution

Unit

Venue

Michael D Lynch

W H Gardner Jr Associate Professor

Duke University

Affiliations

Pratt School of Engineering

Biomedical Engineering

Trinity College of Arts & Sciences

Chemistry

Michael D Lynch is currently serving as a Biomedical Engineering W H Gardner Jr Associate Professor at Duke University.

Honors

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Experiences

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Education

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Michael D Lynch

Duke University

W H Gardner Jr Associate Professor

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biological engineering biotechnology biomolecular engineering molecular biology metabolic engineering biomedical engineering protein engineering genomics genome biology crispr synthetic biology applied microbiology bioinformatics protein science molecular biotechnology protein expression protein purification molecular microbiology gene expression biochemical engineering microbial genetics biocatalysis dynamic control gene editing genome analysis microbial physiology gene regulation nanobiotechnology benchmark studies enzyme catalysis purification performance controlled release sustainable chemistry thermal engineering peptides bioenergetics energy research bioresource technology biological chemistry antiviral research biochemical sciences virus research medicinal research multiscale analysis library science continual improvement process sustainable synthesis gene vector host specificity host genetics chemical biotechnology genotype-phenotype association drug development metabolic regulation metabolic control production engineering sustainable chemical production drug manufacture phase separation in-situ conversion antiviral responses large-scale bioprocess competitiveness dynamic metabolic control two-stage fermentations library enrichment adipic acid critical review cost competitive synthesis redox balance sos response transient inhibition host reca activity phosphate depletion recombinant protein expression biotechnological production process biochemistry pathway engineering genetic engineering energy biotechnology engineering microbes microbial cell factory bacteria biotechnology advance microbiology industrial chemicals

Notable Scholarly Works

Notable Federal Grants

Collaborators

2-Stage Microfermentations. Metabolic Engineering Communications (2024)

Shuai LiZhixia YeEirik A. MorebRomel Menacho-MelgarMaximillian GolovskyMichael D. Lynch

microbiologybiomedical engineeringmetabolic engineeringbiological engineering

Phase Separation Methods for Protein Purification: A Meta‐Analysis of Purification Performance and Cost‐Effectiveness. Biotechnology Journal (2024)

John S. DeckerUtsuki YanoRomel Menacho MelgarMichael D. Lynch

biomolecular engineeringphase separationbiological engineeringbiomedical engineeringprotein purificationphase separation methodsbiotechnologypurification performance

Scalable, Robust, High-Throughput Expression Purification of Nanobodies Enabled by 2-Stage Dynamic Control. Metabolic Engineering (2024)

Jennifer N HenniganRomel Menacho-MelgarPayel SarkarMaximillian GolovskyMichael D Lynch

biomolecular engineeringhigh-throughput expressionbiological engineeringbiochemical engineeringmetabolic engineeringnanobiotechnology

Two-Stage Dynamic Control Protocol for Cloning, Autoinduction, Autolysis, and Purification of Nanobodies From the E. Coli Cytoplasm V1. (2024)

Jennifer HenniganRomel Menacho MelgarPayel SarkarMaximillian GolovskyMichael Lynch

molecular biologynanobiotechnologybiotechnology

Precipitation and Extraction Methods for Protein Purification: A Meta-Analysis of Purification Performance and Cost-Effectiveness. bioRxiv (Cold Spring Harbor Laboratory) (2023)

John S. DeckerUtsuki YanoRomel Menacho MelgarMichael D. Lynch

performance evaluationextraction methodsprotein purificationpurification performancechemical engineering

Scalable, Robust, High-Throughput Expression, Purification Characterization of Nanobodies Enabled by 2-Stage Dynamic Control. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Jennifer N. HenniganRomel Menacho-MelgarPayel SarkarMichael D. Lynch

high-throughput expressionprotein purificationbiomedical engineeringnanoengineeringnanomedicinenanotechnology

A Meta-Analysis of Grna Library Screens Enables an Improved Understanding of the Impact of Grna Folding and Structural Stability on Crispr-Cas9 Activity. The CRISPR Journal (2022)

Eirik A. MorebMichael D. Lynch

geneticsgrna foldingbioinformaticsgrna library screenscrisprgenome biologymolecular biologystructural stability

Integrated Autolysis, Dna Hydrolysis and Precipitation Enables an Improved Bioprocess for Q-Griffithsin, a Broad-Spectrum Antiviral and Clinical-Stage Anti-Covid-19 Candidate. Biochemical Engineering Journal (2022)

John S. DeckerRomel Menacho-MelgarMichael D. Lynch

antiviral drug developmentviral diagnosticsbiochemical engineeringmolecular engineeringbiological chemistryantiviral responsesantiviral therapyvirus researchvirologybiochemical sciencesbiochemistrybiotechnologymedicinal researchimproved bioprocesscovid-19antiviral researchbiomolecular engineeringbiocatalysisbiological engineeringdna hydrolysis

Measuring Oligonucleotide Hydrolysis in Cellular Lysates via Viscosity Measurements. BIO-PROTOCOL (2022)

Romel Menacho-MelgarMichael D Lynch

biophysicsoligonucleotide hydrolysiscell biologyviscosity measurementscellular lysatesmolecular biologystructural biology

“Multiagent” Screening Improves Directed Enzyme Evolution by Identifying Epistatic Mutations. ACS Synthetic Biology (2022)

Tian YangZhixia YeMichael D. Lynch

enzyme evolutionbiological engineeringepistatic mutationssynthetic biology

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Michael D Lynch

W H Gardner Jr Associate Professor

Duke University

Affiliations

Pratt School of Engineering

Biomedical Engineering

Trinity College of Arts & Sciences

Chemistry

Michael D Lynch is currently serving as a Biomedical Engineering W H Gardner Jr Associate Professor at Duke University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Michael D Lynch

Duke University

W H Gardner Jr Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

2-Stage Microfermentations. Metabolic Engineering Communications (2024)

Shuai LiZhixia YeEirik A. MorebRomel Menacho-MelgarMaximillian GolovskyMichael D. Lynch

microbiologybiomedical engineeringmetabolic engineeringbiological engineering

Phase Separation Methods for Protein Purification: A Meta‐Analysis of Purification Performance and Cost‐Effectiveness. Biotechnology Journal (2024)

John S. DeckerUtsuki YanoRomel Menacho MelgarMichael D. Lynch

biomolecular engineeringphase separationbiological engineeringbiomedical engineeringprotein purificationphase separation methodsbiotechnologypurification performance

Scalable, Robust, High-Throughput Expression Purification of Nanobodies Enabled by 2-Stage Dynamic Control. Metabolic Engineering (2024)

Jennifer N HenniganRomel Menacho-MelgarPayel SarkarMaximillian GolovskyMichael D Lynch

biomolecular engineeringhigh-throughput expressionbiological engineeringbiochemical engineeringmetabolic engineeringnanobiotechnology

Two-Stage Dynamic Control Protocol for Cloning, Autoinduction, Autolysis, and Purification of Nanobodies From the E. Coli Cytoplasm V1. (2024)

Jennifer HenniganRomel Menacho MelgarPayel SarkarMaximillian GolovskyMichael Lynch

molecular biologynanobiotechnologybiotechnology

Precipitation and Extraction Methods for Protein Purification: A Meta-Analysis of Purification Performance and Cost-Effectiveness. bioRxiv (Cold Spring Harbor Laboratory) (2023)

John S. DeckerUtsuki YanoRomel Menacho MelgarMichael D. Lynch

performance evaluationextraction methodsprotein purificationpurification performancechemical engineering

Scalable, Robust, High-Throughput Expression, Purification Characterization of Nanobodies Enabled by 2-Stage Dynamic Control. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Jennifer N. HenniganRomel Menacho-MelgarPayel SarkarMichael D. Lynch

high-throughput expressionprotein purificationbiomedical engineeringnanoengineeringnanomedicinenanotechnology

A Meta-Analysis of Grna Library Screens Enables an Improved Understanding of the Impact of Grna Folding and Structural Stability on Crispr-Cas9 Activity. The CRISPR Journal (2022)

Eirik A. MorebMichael D. Lynch

geneticsgrna foldingbioinformaticsgrna library screenscrisprgenome biologymolecular biologystructural stability

John S. DeckerRomel Menacho-MelgarMichael D. Lynch

Measuring Oligonucleotide Hydrolysis in Cellular Lysates via Viscosity Measurements. BIO-PROTOCOL (2022)

Romel Menacho-MelgarMichael D Lynch

biophysicsoligonucleotide hydrolysiscell biologyviscosity measurementscellular lysatesmolecular biologystructural biology

“Multiagent” Screening Improves Directed Enzyme Evolution by Identifying Epistatic Mutations. ACS Synthetic Biology (2022)

Tian YangZhixia YeMichael D. Lynch

enzyme evolutionbiological engineeringepistatic mutationssynthetic biology

1
2
3
4
5
6
10 / page

Similar Faculty Members

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Similar Faculty Members

Kristala L. Jones Prather

Institution

Massachusetts Institute of Technology

biotechnology

biological engineering

Mark A. Eiteman

Institution

University of Georgia

applied microbiology

microbiology

Daniel Olson

Institution

Dartmouth College

cellulosic biofuel

molecular biology

Yajun Yan

Institution

University of Georgia

synthetic biology

metabolic engineering

James H. Clark

Institution

Stanford University

synthetic biology

biotechnology advance

Ian Wheeldon

Institution

University of California, Riverside

bioenergy

synthetic biology

Richard Willson

Institution

University of Houston

biomolecular recognition

biomolecular analysis

Janet Westpheling

Institution

University of Georgia

genomics

metabolic engineering

Christopher A. Voigt

Institution

Massachusetts Institute of Technology

biological engineering

synthetic biology

Ka-Yiu San

Institution

Rice University

biotechnology

biological engineering