Faculty

Institution

Unit

Venue

Michael Dee Gunn

Duke University

Affiliations

Duke University School of Medicine

Clinical Research Training Program

Pathology

NoneMichael Dee Gunn is currently serving as a Clinical Research Training Program faculty at Duke University.

Honors

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Experiences

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Michael Dee Gunn

Duke University

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immunology immune responses pharmacology respiratory medicine inflammation adaptive immune system cell biology hematology medicinal research mammalian biology medicine cancer immunotherapy clinical immunology oncology cytokines cellular therapy innate immune system cellular immune responses receptors membrane biology gene expression vascular biology experimental medicine liver physiology brain tumor research clinical microbiology molecular immunology host response cellular physiology cell death leukemia experimental biology cancer cells molecular physiology lymphatic system cancer biology cancer treatment lymph nodes enzyme inhibition apoptosis respiration (physiology) vaccine development vaccine efficacy vaccine research host factors inhalation toxicology laboratory medicine lymphocyte development cell adhesion immunopathology immunophenotyping chronic inflammation receptor (biochemistry) clinical pathology veterinary pathology medical genetics clinical medicine clinical physiology pulmonary diseases therapeutic efficacy immune checkpoint inhibitors noninfectious lung injury dendritic cell localization lymphocyte homing b-cell-homing chemokine lymphoid follicles brain tumours brain immunology mouse lymph nodes plasmacytoid dendritic cells stromal cell expression tumor necrosis factor tetanus toxoid dendritic cell vaccines glioblastoma patients exudate macrophages

Notable Scholarly Works

Notable Federal Grants

Collaborators

Altered Ontogeny and Transcriptomic Signatures of Tissue-Resident Pulmonary Interstitial Macrophages Ameliorate Allergic Airway Hyperresponsiveness. Frontiers in Immunology (2024)

Robert M. TigheAnastasiya BirukovaYuryi MalakhauYoshihiko KobayashiAaron T. VoseVidya ChandramohanJaime M. Cyphert-DalyR. Ian CummingHelene Fradin KirshnerPurushothama R. TataJennifer L. IngramMichael D. GunnLoretta G. QueYen-Rei A. Yu

molecular immunologyinflammationtranscriptomic signaturesimmunopathologyimmunologyrespiratory medicinedermatologyallergyimmune responsesmammalian biology

Recapitulation of Human Pathophysiology and Identification of Forensic Biomarkers in a Translational Model of Chlorine Inhalation Injury. American journal of physiology. Lung cellular and molecular physiology (2024)

Sven-Eric JordtMichael A. GentileCarolyn J. AlbertKevin A. SchulteBrooke G. PantazidesBrian S. CrowJennifer Quiñones-GonzálezJonas W. PerezDavid A. FordRakesh P. PatelThomas A. BlakeMichael D. GunnSatyanarayana Achanta

public healthhuman pathophysiologychlorine inhalation injuryforensic biomarkersphysiologyrespiratory medicinetranslational modelmolecular physiologymembrane biologyhealth sciences

Allergic Asthma Responses Are Dependent on Macrophage Ontogeny. bioRxiv (Cold Spring Harbor Laboratory) (2023)

asthmaimmunologyrespiratory medicinedermatologydevelopmental biologyallergic asthma responsesmacrophage ontogeny

A Novel Mhc-Independent Mechanism of Tumor Cell Killing by Cd8 + T Cells. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Emily LernerKarolina WoronieckaVincent D’AnniballeDaniel WilkinsonSelena LorreyJessica Waibl-PolaniaLucas WachsmuthAlexandra MiggelbrinkJude RajAditya MohanSarah CookWilliam TomaszewskiXiuyu CuiMustafa KhasrawMichael D. GunnPeter E. Fecci

cell deathimmunologynovel mhc-independent mechanismcarcinogenesiscellular immune responsesadaptive immune systemtumor biologycell signalingnon-host resistancecell biologymolecular biologycancer cellsoncogenestumor cellapoptosismedicinal researchmolecular cancerinflammationimmune responseshost factors

Antigen-Loaded Monocyte Administration and Flt3 Ligand Augment the Antitumor Efficacy of Immune Checkpoint Blockade in a Murine Melanoma Model. Journal of Immunotherapy (2023)

Vincent M. D’AnniballeMin-Nung HuangBenjamin D. LueckLowell T. NicholsonIan McFatridgeMichael D. Gunn

immune checkpoint blockadeantitumor efficacydermatologypharmacologytherapeutic targetstumor biologycancer immunotherapymelanomaimmunotherapymurine melanoma modeltumor suppressorscancer treatmentmolecular cancercellular therapyimmune checkpoint inhibitorscancer careantigen-loaded monocyte administrationtumor targetingmedicineclinical transplantationleukemiaoncology

Antigen Loaded Monocytes Prime Cd4+ T Cell Responses Through Notch2 Dependent Cdc2. The Journal of Immunology (2023)

Benjamin D LueckVincent M D’AnniballeMichael D Gunn

immunologycell biologycellular immune responsesimmune responsesadaptive immune systemgene expressioncytokines

Cd8+ T Cells Maintain Killing of Mhc-I-Negative Tumor Cells Through the Nkg2D–Nkg2Dl Axis. Nature Cancer (2023)

Emily C LernerKarolina I WoronieckaVincent M D'AnniballeDaniel S WilkinsonAditya A MohanSelena J LorreyJessica Waibl-PolaniaLucas P WachsmuthAlexandra M MiggelbrinkJoshua D JacksonXiuyu CuiJude A RajWilliam H TomaszewskiSarah L CookJohn H SampsonAnoop P PatelMustafa KhasrawMichael D GunnPeter E Fecci

apoptosistumor biologycancer immunotherapycell deathimmunologymhc-i-negative tumor cellscancer researchimmune responsescellular immune responsesadaptive immune systemcancer cellshost factorsoncologycancer biology

Immunotoxin-αCd40 Therapy Activates Innate and Adaptive Immunity and Generates a Durable Antitumor Response in Glioblastoma Models. Science Translational Medicine (2023)

Scott ParkerCharlotte McDowallLuis Sanchez-PerezCristina OsorioPatrick C. DunckerAaron BrileyAdam M. SwartzJames E. HerndonYen-Rei A. YuRoger E. McLendonThomas F. TedderAnnick DesjardinsDavid M. AshleyMichael Dee GunnDavid S. EnterlineDavid A. KnorrIra H. PastanSmita K. NairDarell D. BignerVidyalakshmi Chandramohan

immunotoxicologyimmunologyadaptive immune systemclinical immunologytumor biologycancer immunotherapyadaptive immunityimmunotherapydurable antitumor responsecancer treatmenthealth sciencesmedicinal researchcancer careglioblastoma modelsbrain tumor researchimmunomodulationmedicineexperimental medicineoncologyneuro-oncology

Abstract 1378: Cd8 T Cell Mediated Killing of Mhc Class 1 Negative Tumors Requires Antigen Presenting Myeloid Cells and Interferon Gamma. Cancer Research (2022)

Emily LernerVincent D'AnniballeWilliam TomaszewskiJonathan PereraXiuyu CuiJessica Waibl-PolaniaDaniel WilkinsonMichael D. GunnPeter E. FecciKarolina Woroniecka

pathologycell deathimmunologycellular immune responsesadaptive immune systemmyeloid neoplasiatumor biologycancer immunotherapycell biologycancer researchnegative tumorscancer treatmentcancer cellsmyeloid cellsinterferon gammamedicinal researchcellular therapycancer biologyimmune responsesleukemiaoncology

Lessons From the Pandemic: Responding to Emerging Zoonotic Viral Diseases—a Keystone Symposia Report. Annals of the New York Academy of Sciences (2022)

Jennifer CableAnthony FauciWilliam E. DowlingStephan GüntherDennis A. BentePragya Dhruv YadavLawrence C. MadoffLin‐Fa WangRahul K. AroraMaria Van KerkhoveMay C. ChuThomas JaenischJonathan H. EpsteinSimon David William FrostDaniel G. BauschLisa E. HensleyÉric BergeronIoannis SitarasMichael D. GunnThomas W. GeisbertCésar Muñoz‐FontelaFlorian KrammerEmmie de WitPontus NordenfeltErica Ollmann SaphireSarah C. GilbertKizzmekia S. CorbettLuis M. BrancoSylvain BaizeNeeltje van DoremalenMarco A. KriegerSue Ann Costa ClemensRenske HesselinkDan Hartman

public healthepidemiologyvirologyzoonotic viral diseasesglobal healthcovid-19 pandemic

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Michael Dee Gunn

Duke University

Affiliations

Duke University School of Medicine

Clinical Research Training Program

Pathology

NoneMichael Dee Gunn is currently serving as a Clinical Research Training Program faculty at Duke University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Michael Dee Gunn

Duke University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Altered Ontogeny and Transcriptomic Signatures of Tissue-Resident Pulmonary Interstitial Macrophages Ameliorate Allergic Airway Hyperresponsiveness. Frontiers in Immunology (2024)

molecular immunologyinflammationtranscriptomic signaturesimmunopathologyimmunologyrespiratory medicinedermatologyallergyimmune responsesmammalian biology

public healthhuman pathophysiologychlorine inhalation injuryforensic biomarkersphysiologyrespiratory medicinetranslational modelmolecular physiologymembrane biologyhealth sciences

Allergic Asthma Responses Are Dependent on Macrophage Ontogeny. bioRxiv (Cold Spring Harbor Laboratory) (2023)

asthmaimmunologyrespiratory medicinedermatologydevelopmental biologyallergic asthma responsesmacrophage ontogeny

A Novel Mhc-Independent Mechanism of Tumor Cell Killing by Cd8 + T Cells. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Antigen-Loaded Monocyte Administration and Flt3 Ligand Augment the Antitumor Efficacy of Immune Checkpoint Blockade in a Murine Melanoma Model. Journal of Immunotherapy (2023)

Vincent M. D’AnniballeMin-Nung HuangBenjamin D. LueckLowell T. NicholsonIan McFatridgeMichael D. Gunn

Antigen Loaded Monocytes Prime Cd4+ T Cell Responses Through Notch2 Dependent Cdc2. The Journal of Immunology (2023)

Benjamin D LueckVincent M D’AnniballeMichael D Gunn

immunologycell biologycellular immune responsesimmune responsesadaptive immune systemgene expressioncytokines

Cd8+ T Cells Maintain Killing of Mhc-I-Negative Tumor Cells Through the Nkg2D–Nkg2Dl Axis. Nature Cancer (2023)

Immunotoxin-αCd40 Therapy Activates Innate and Adaptive Immunity and Generates a Durable Antitumor Response in Glioblastoma Models. Science Translational Medicine (2023)

Abstract 1378: Cd8 T Cell Mediated Killing of Mhc Class 1 Negative Tumors Requires Antigen Presenting Myeloid Cells and Interferon Gamma. Cancer Research (2022)

Emily LernerVincent D'AnniballeWilliam TomaszewskiJonathan PereraXiuyu CuiJessica Waibl-PolaniaDaniel WilkinsonMichael D. GunnPeter E. FecciKarolina Woroniecka

Lessons From the Pandemic: Responding to Emerging Zoonotic Viral Diseases—a Keystone Symposia Report. Annals of the New York Academy of Sciences (2022)

public healthepidemiologyvirologyzoonotic viral diseasesglobal healthcovid-19 pandemic

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